Articles tagged with Monkeypox
A large contact tracing investigation found no secondary cases of monkeypox, informing estimates of exposure risk and postexposure prophylaxis recommendations. The framework's ease of application and cross-setting use has important applications for future infection prevention efforts.
A case study presents a 30-year-old man with painful itchy skin lesions primarily in the genital region, which evolved into centrally indented papules and hemorrhagic crusts. PCR analysis confirmed the diagnosis of West African variant monkeypox, highlighting the importance of considering clinical courses during outbreaks.
A new assessment of monkeypox infections in the Democratic Republic of the Congo shows rising transmission rates, approaching the point where outbreaks are likely to be larger and more frequent. The study highlights the potential for sustained local outbreaks and increased risks of new outbreaks globally.
Researchers identified specific monkeypox mutations that contribute to its continued infectiousness. The virus is accumulating mutations where drugs and antibodies from vaccines are supposed to bind, making it smarter and more infectious.
A UK study found substantial monkeypox transmission before symptoms appear, with 53% of cases occurring pre-symptomatically. The study's findings have important implications for infection control globally and may affect isolation and contact tracing policies.
According to a review by Petra Zimmermann and Nigel Curtis, children under 8 are at higher risk of complications from monkeypox disease. The authors emphasize the need for smallpox vaccination as an effective way to prevent the spread of monkeypox among young children.
The Annenberg Science and Public Health Knowledge Monitor assesses public knowledge on climate, maternal health, vaccination, and more. The quarterly survey reports aim to highlight strengths and weaknesses in public knowledge and inform public health strategies.
A survey among European gay-dating app users found a 82% crude vaccination acceptance rate. Willingness to vaccinate increased with factors like perceived severity of monkeypox, transmission risk, and existing health links. Higher acceptance rates were seen in northern and western Europe compared to southern and eastern regions.
Nurses play a key role in combating stigma by educating healthcare professionals about safe spaces for affected individuals, regardless of sexual behavior or co-infections. Accurate messaging is crucial to prevent misinformation and promote proper care and counseling.
The study will gather data from over 500 adults with monkeypox to determine the effectiveness and safety of tecovirimat. Participants with severe disease or high risk of severe disease will receive open-label tecovirimat, while others will be randomly assigned to receive either tecovirimat or placebo.
Scientists have detected monkeypox virus in the testes of macaques during acute infection and found preliminary evidence of persistent infection in two convalescent animals. The study highlights the potential for sexual transmission of the virus in humans, particularly in convalescent male patients.
Researchers from Boston University have developed novel compounds that can inhibit the replication of multiple poxviruses, including smallpox and monkeypox. These findings hold promise for a new class of antipoxviral agents as broad-spectrum small molecules with significant potential as an antiviral therapy.
A clinical trial begins in the Democratic Republic of Congo to evaluate tecovirimat's safety and effectiveness in treating monkeypox. The trial will enroll up to 450 participants, comparing those who receive tecovirimat to placebo, and gather data on disease severity, mortality, and recovery.
A new scoring tool prioritizes countries with higher vaccination rates and vulnerable populations, aiming to allocate Covid-19 vaccines more fairly. The tool considers a broader range of factors than current global COVAX facilities, which have been criticized for insufficient access.
The current global monkeypox outbreak emphasizes the importance of a preventative One Health approach to minimize the risk of future emergence of known and unknown zoonotic pathogens. This is particularly crucial with the majority of people worldwide living in high population densities in cities, facilitating the spread of infectious d...
A new study from the University of Maryland cautions that delayed interventions make it harder to eliminate monkeypox. The research suggests that stronger and better-adapted variants may evolve if case numbers are low, making it challenging to control outbreaks.