Articles tagged with Oral Cancer
A study published in General Dentistry has found that the VELscope device can detect oral HPV lesions, allowing for early detection and treatment of oral cancer. Regular dental check-ups and screenings are crucial in preventing and detecting oral cancer.
A new study published in the Journal of Prosthodontics found that the absence of Human calmodulin-like protein (CLP) in oral epithelial cells may indicate oral cancer. The researchers used staining to compare CLP expression in normal and cancerous tissues, revealing a significant decrease or complete lack of CLP in malignant regions.
The majority of oral cancers are found late, causing high mortality rates, but early diagnosis improves survivability to 95% and reduces morbidity. Prosthodontists must change their practice paradigm by performing regular oral cancer screening examinations on all patients.
A new Cornell study found a strong relationship between allergies and cancer in tissues exposed to environmental factors, such as eczema, hives, and hay fever. Allergies linked to these conditions were most strongly associated with lower rates of cancers in exposed tissues.
A comprehensive assessment of HPV-associated cancers found significant racial disparities, with higher rates among African American women and Hispanic men. The study also identified the most common types of HPV-related cancers, including cervical, anal, and oral cancers.
A recent study found that HPV vaccination can reduce the incidence of HPV-caused cancers, particularly oral and anal cancers, which are rising in incidence. Researchers propose a simple oral screening test using 'swish and spit' rinses to detect high-risk infections.
A large population study found a significant association between incense use and an increased risk of upper respiratory tract cancers, including squamous cell carcinomas. The study also suggested that incense smoke may add to the cancer risk in smokers, but not in non-smokers.
Research finds that smokeless tobacco products carry a lower cancer risk compared to smoking, particularly for oral and oesophageal cancers. However, users are still at increased risk of other types of cancer, such as lung cancer, especially in countries with high STP use.
A phase II study found that adding cetuximab to chemotherapy improves response rates in head and neck cancer patients, with 86% of patients responding to induction treatment. The addition also led to significant tumor reduction and improved cancer-free survival rates over two years.
Researchers have developed novel approaches to analyze proteins in human saliva and diseased heart tissue, potentially leading to earlier diagnoses of heart disease and oral cancer. By tracking changes in protein profiles over time, scientists may identify key biomarkers for therapeutic intervention.
A new robotic surgery technique called transoral robotic surgery (TORS) has been shown to be effective in removing tonsil cancer with minimal complications and improved patient outcomes. In a study of 27 patients, surgeons successfully removed all cancerous tissues in 93% of cases, with an average surgery time of one hour and 43 minutes.
Research presents findings on plant-derived cancer medicines, highlighting the potential of black raspberry gel in preventing or slowing the growth of oral premalignant tumors. The study demonstrates that the gel slows or reduces lesion progression in about two-thirds of study participants, with no reported side effects.
Researchers discovered that different ethnic groups living in California manifest the disease very differently, with African Americans and Caucasians developing tongue cancer at higher rates. Cultural habits such as cigarette smoking and areca nut chewing contribute to the prevalence of oral cancer in certain groups.
Researchers at Ohio State University found that extracts from Hass avocados kill or stop the growth of pre-cancerous cells leading to oral cancer. The study highlights the potential health benefits of consuming phytonutrient-rich foods like avocados.
A large prospective study confirmed strong associations between current and past cigarette smoking and malignancies of the head and neck in both genders. Smoking plays a greater role in developing head and neck cancer in women than men, with higher incidence rates and relative increases in risk.
A growing trend in oropharyngeal cancers is attributed to HPV infection, especially in younger males. This emerging epidemic warrants the exploration of HPV vaccine efficacy and safety in male populations.
A University of Illinois Chicago study found that over 92% of Illinois dentists perform oral cancer examinations, but many lack proper training and techniques, leading to incomplete screenings. The study emphasizes the need for additional training and increased vigilance in detecting oral cancers.
A study found that men with chronic gum disease were at higher risk for tongue cancer, regardless of smoking status. Periodontitis was significantly associated with an increased risk of tongue cancer in a study of 51 white men.
Researchers at the University at Buffalo have discovered a significant association between chronic gum disease and the risk of tongue cancer. The study found that every millimeter of alveolar bone loss increases the risk five-fold, with no effect from other conditions.
Researchers found that oral HPV infection is the strongest risk factor for throat cancers in both men and women. Consistent condom use may reduce risk, while tobacco and alcohol use do not increase the risk of HPV-linked cancer.
Dr. Kenneth Stephen has made a major international contribution to the field of dental public health, with over 30 years of groundbreaking research on caries prevention and oral health promotion. His work has led to significant advancements in fluoride delivery methods and oral cancer screening.
Researchers developed a new screening process using chemiluminescent light and toluidine blue dye to improve diagnosis accuracy for early-stage oral cancer. The study found that this approach can reduce unnecessary biopsies and false negatives, leading to better patient outcomes.
Researchers investigated nutritional links between smoking and oral cancer, finding folate levels lower in smokers' blood and cheek cells. Smokers also had altered forms of folate distribution, while antioxidants like carotenoids and vitamin E showed similar trends. More studies are needed to clarify these findings.
The Mayo Clinic has pioneered a novel method of jaw reconstruction for oral cancer patients, utilizing distraction osteogenesis after tumor removal surgery. This approach enables patients to receive both radiation therapy and reconstruction concurrently, minimizing scar tissue and improving patient tolerance.
Cysteine-containing chewing gum may help eliminate acetaldehyde, a carcinogenic compound found in saliva and upper digestive tract. Long-term randomized controlled trials are needed to prove its potential cancer-preventive effects.
The VELScope device emits blue light, causing cells to absorb energy and re-emit fluorescence, helping dentists detect abnormal tissue. The device correctly identified all normal biopsies and 98% of cancers, offering a promising solution for early oral cancer detection.
Scientists have developed a standardized saliva RNA test for oral cancer detection, showing high accuracy rates in detecting oral cancer. The test has been confirmed to be highly accurate in identifying four saliva oral cancer RNA biomarkers, reducing mortality and morbidity for oral cancer patients.
Researchers at Virginia Tech have developed a new bone tissue engineering material using amorphous calcium phosphates, which they believe could lead to faster and higher quality bone formation. The team's work, in collaboration with the American Dental Association, is currently in press for several scientific journals.
Researchers found that NSAIDs reduced oral cancer risk by 53% in smokers and active users. However, long-term use of NSAIDs doubled the relative risk of death due to heart disease.
Despite declining overall mortality, US cancer incidence rose slightly among women in 2002 compared to the previous decade. The study also found that some cancers, like leukemia and non-Hodgkin lymphoma, experienced increased incidence.
Researchers found that lesions stained with toluidine blue were six times more likely to become oral cancers and contained molecular alterations linked to high risk. The dye-staining lesions had characteristic molecular changes that predicted higher risk for oral cancers, even at early stages.
Researchers at Forsyth Institute have identified three bacteria associated with oral squamous cell carcinoma (OSCC), a deadly form of cancer. The study found that elevated levels of these bacteria in saliva can indicate the presence of OSCC, raising hopes for an early diagnostic marker and potentially saving lives.
A study found six common bacteria in OSCC patients at significantly higher levels than controls. Three species were found to correctly predict over 80% of oral cancer cases, offering a potential non-invasive diagnostic test.
A pooled analysis of 15,000 individuals found that current drinkers had a 27% lower risk of non-Hodgkin's lymphoma compared to non-drinkers. The risk did not vary with alcohol consumption type or age of onset, but was lowest for Burkitt's lymphoma subtype.
A new study suggests that regular oral visual screening can significantly reduce mortality from mouth cancer, particularly among tobacco/alcohol users. The research found a 50% increase in 5-year survival rates and a 34% reduction in mortality for those screened, highlighting the potential of this simple yet effective procedure to save...
A population-based study found that long-term NSAID use significantly reduced the risk of developing oral cancer in light to moderate smokers, with a 65% decrease observed compared to non-NSAID users. The most effective NSAIDs were those used by smokers with low pack-year tobacco consumption.
Researchers found that zinc supplements reversed precancerous conditions in the esophagus and tongue of zinc-deficient rats. The study suggests that zinc supplements may prevent the development of esophageal or oral cancers, which are associated with nutritional zinc deficiency.
Researchers discovered distinct patterns of mRNA in saliva that can indicate developing oral cancer. The study found that a salivary test could identify cancer patients with high accuracy, potentially replacing current diagnostic tests.
A large study of over 400 oral cancer cases and 600 healthy controls found no link between marijuana use and increased risk of oral cancer. Marijuana users with certain genetic variations were also not at higher risk than those with normal genes.
A recent survey conducted by Case Western Reserve University found that most dental hygienists prioritize oral cancer screening but often fall short in performing head and neck examinations and counseling patients about tobacco use. The study emphasizes the crucial role of dental professionals in early detection and treatment.
Dr. Gutkind received the IADR Oral Medicine/Pathology Research Award for his seminal research on normal and oncogenic functions of non-receptor protein-tyrosine kinases. He has published over 200 scientific papers and contributed to developing molecular markers of disease progression in oral malignancies.
Researchers found that calcium supplements reduced the risk of colorectal cancer recurrence only among individuals with baseline vitamin D levels above the median. Serum vitamin D levels were also associated with reduced adenoma recurrence among individuals taking calcium supplements.
Researchers analyzed data from NHANES III to find that serious periodontal disease doubles the risk of pre-cancerous lesions and quadruples the risk of oral tumors. The study suggests a potential link between gum disease and oral cancer, with implications for early detection and prevention.
Researchers developed new techniques to improve both quality of life and surgical outcomes for patients with oral cancer. The study involved 43 patients, who received tongue reconstruction after half or more of the tongue was removed.
A study found that long-term oral contraceptive use is associated with a 33% increase in breast cancer risk among women with BRCA1 mutations, particularly those who started using contraceptives before age 30. In contrast, no significant increase in breast cancer risk was observed in women with BRCA2 mutations.
A Norwegian study demonstrates that COX-2 inhibitors (coxibs) can be effective in preventing oral cancer by targeting high-risk individuals. The study's results suggest that coxibs may be a promising approach to chemoprevention, particularly for head and neck cancer patients.
A comprehensive periodontal examination can save lives by detecting undiagnosed protein S deficiency, a condition that causes thrombotic disorders and increases the risk of strokes and heart attacks. Early diagnosis is key to successful treatment outcomes and improved survival rates for patients with this condition.
Researchers mapped the 11q13 amplicon, a common genetic defect in oral and head and neck cancers. A new gene, TAOS1, was identified as overexpressed in cell lines with 11q13 amplification, suggesting its potential as a biomarker for diagnosis and prognosis.
A study found that young users of smokeless tobacco lack awareness of its health risks, with only 74% knowing it's harmful to their health. The survey also revealed that users often describe themselves as 'cool' and 'macho', reflecting the tobacco industry's marketing efforts.
The study shows how chromosomes are distributed unevenly during cancer cell division, leading to genetic defects and abnormal growth. The researchers also discovered a breakage-fusion-bridge cycle that can amplify gene copies contributing to cancer growth.
A University of Iowa research team discovered that DNA methylation can contribute to oral cancer by silencing tumor suppressor genes. The study found that aberrant cytosine methylation patterns were present in oral cancer cells but not in normal human cells, suggesting a potential mechanism for cancer progression.