Articles tagged with Blood Pressure
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Researchers at UT Southwestern Medical Center have found that C-Reactive Protein (CRP) directly induces hypertension in mice. The study, which manipulated CRP levels in mice with an engineered gene, showed a direct correlation between CRP and blood pressure elevation.
Researchers found that a core clock gene regulates stress response and blood pressure, providing a novel link to the diurnal variation in heart attack risk. The study suggests modifying the molecular clock using drugs could be a treatment for people with high blood pressure.
Adolescents with parents in the military experience increased stress and physiological changes during wartime, including higher blood pressure and heart rates. Researchers found that these effects were particularly pronounced in children of deployed parents.
A recent study of 4,500 American adolescents found that sedentary activities and higher body mass index (BMI) are associated with higher systolic blood pressure. Encouraging adolescents to reduce their sedentary activity may improve their blood pressure and lower their later risk of cardiovascular disease.
Researchers found a strong association between high blood pressure during pregnancy and increased coronary calcification later in life. Women who developed hypertension during pregnancy were at a 57% higher risk of cardiovascular disease, including type-2 diabetes and heart disease.
Individuals with diagnosed hypertension in the US have lower blood pressure readings and better control compared to those in five Western European countries. The study found that treatment thresholds are more aggressive in the US, resulting in higher rates of hypertension control.
US physicians tend to start treatment sooner and are more aggressive in controlling blood pressure, with 63% of patients having their blood pressure under control. However, vast room for improvement exists, with less than two-thirds of patients reaching guideline-set goals.
A new study finds that tanshinone IIA, an active ingredient in the Chinese herb danshen, significantly reduces blood pressure in hamsters. The treatment also enhances expression of endothelial nitric oxide synthase and increases production of nitric oxide.
A study found that switching patients to more affordable cholesterol and blood pressure medications saved the UK's National Health Service £26,000 annually. The switch was made without adverse events and was successful for the majority of patients.
Research suggests that inflammatory genes may play a key role in salt-sensitive hypertension, which affects nearly one-third of Americans. The study investigates the connection between stress, inflammation, and sodium handling, with potential therapeutic implications for high blood pressure management.
A $1.7 billion North American study aims to answer whether reopening narrowed kidney arteries benefits patients. Researchers will compare medical management with medicines coupled with stents, stainless steel scaffolds inserted into blood vessels.
Researchers found that genetic variations impact blood pressure differently in men and women, suggesting a need to consider gender when diagnosing and treating hypertension. The study identified six genes with varying frequency of variation between sexes and extreme blood pressure levels.
A device implanted in US patients with severe hypertension shows significant reduction in blood pressure, averaging 22mmHg systolic and 18mmHg diastolic. The Rheos System activates the body's baroreflex system to lower blood pressure through electrical stimulation.
Researchers found that pioglitazone reduced carotid artery intima-media thickness by .001 millimeters and improved blood glucose control, while increasing HDL cholesterol levels. These findings suggest pioglitazone may be a new approach to further reduce cardiovascular risk in patients with type 2 diabetes.
A study found that heart failure patients with higher systolic blood pressures had lower death rates compared to those with lower pressures. Lower systolic pressures may indicate more advanced disease and a poorer prognosis.
Researchers highlight the importance of understanding risk factors for heel ulcers, which are often linked to peripheral neuropathy and diminished vascular function. Additionally, studies demonstrate the effectiveness of lateral-wedge insoles in relieving pain and stiffness in people with knee osteoarthritis. The study also explores th...
Hydrogen sulfide gas induces a state of suspended animation in mice, maintaining normal blood pressure, which may help treat critically ill patients. The gas reduces metabolic rate and body temperature, but surprisingly does not decrease blood pressure.
A new multicenter research consortium, called Protocolized Care for Early Septic Shock (ProCESS), is beginning a large-scale study to determine whether specific interventions can halt the progression to severe sepsis and septic shock. The project aims to establish standard procedures to diagnose and treat sepsis in emergency departments.
A University of Alberta study found that walking alone is unlikely to produce marked health benefits compared to more intense exercise programs. Regular moderate activity and occasional vigorous periods are crucial for optimal health outcomes.
A recent study reveals that older women have as many risk factors for heart disease as men in their 60s and more by their 70s. The research, led by USC demographers, shows a shift from previous decades where older men were at greater risk.
A new study published in the Lancet found that aggressive treatment to lower blood pressure significantly reduces the risk of stroke and heart attack. The research, which involved over 160,000 individuals in 50 countries, highlights the importance of driving blood pressure down to very low levels rather than choosing specific medications.
A study published in the Journal of Gerontology found that higher blood pressure is associated with a decline in walking ability in older persons. The research, led by Dr. Raj Shah, suggests that controlling blood pressure may help prevent gait difficulties in older adults.
A study compares kidney transplant outcomes in the US and Spain, finding similar one-year and five-year graft survival rates for heart-beating and non-heart-beating donors. Living kidney donors also experience higher blood pressure years after donation, highlighting implications for informed consent and follow-up care.
A study found that increased nighttime blood pressure may be associated with a higher risk of developing congestive heart failure. Analyzing data from 951 elderly men, researchers discovered that a 9–mm Hg increase in nighttime ambulatory diastolic blood pressure and non-dipping blood pressure patterns were significant predictors of CHF.
A Mayo Clinic study found that patients with widely fluctuating blood pressure during the first three hours in the emergency room were much less likely to survive more than 90 days after a stroke. The study suggests that managing blood pressure acutely after ischemic stroke is crucial to improve survival rates.
Researchers found that healthy black girls experience a significant drop in estrogen levels during stress, leading to increased blood pressure and elevated risk of heart disease. In contrast, white teens maintain consistent estrogen levels, reducing their blood pressure response to stress.
Researchers investigate sodium channel genes to identify genetic predictors of hypertension and develop screening methods for high blood pressure in the general population. A study involving 300 healthy youth will measure sodium handling after environmental stress and analyze their genes to correlate with impaired natriuresis.
Researchers found that a combination of beta-blockers, calcium antagonists, and ACE inhibitors effectively lowers blood pressure in Hispanic patients while reducing their risk of developing diabetes. The study showed a 19% increased risk of diabetes in Hispanic patients but a 15% decreased risk with the verapamil-trandolapril strategy.
A new study found that a nighttime breathing mask can significantly reduce blood pressure in individuals with moderate to severe sleep apnea. The researchers also discovered that correcting oxygen levels alone may not be enough to lower blood pressure.
A study using RESPeRATE, a device-guided paced breathing system, found significant reductions in blood pressure and peripheral resistance in hypertensive patients. The treatment group showed a greater systolic BP reduction correlated with the total time spent in slow breathing.
The World Hypertension League is calling for better awareness of high blood pressure patients reaching the internationally-recognised goal of 140/90mmHg or lower. Despite this, around 50-70% of people with high blood pressure worldwide remain above this goal, leaving them at significant risk of cardiovascular disease.
Scientists used RNA interference to block a mineralocorticoid receptor, which signals the body to absorb sodium and water into the bloodstream. The treatment kept blood pressure from worsening but did not eliminate it, and significantly reduced kidney damage in rats.
A University of Chicago study found that lonely individuals have significantly higher blood pressures than non-lonely people, even after accounting for other factors. The researchers discovered a strong link between loneliness and increased blood pressure in aging adults, with the greatest differences observed among older participants.
A recent study by UC Davis researchers found that grape seed extract can significantly reduce blood pressure in individuals with metabolic syndrome. The one-month study involved 24 patients, who experienced an average drop of 12 millimeters in systolic and 8 millimeters in diastolic blood pressure.
The study found that patients with extreme obesity who underwent gastric bypass surgery experienced significant reductions in blood pressure. The majority of these patients were able to reduce or eliminate their blood pressure medications after surgery, while those with normal blood pressure showed no significant changes.
A study of 347 patients who underwent bariatric surgery between 1992 and 2001 found a significant reduction in blood pressure 18 months post-surgery. Systolic and diastolic blood pressures decreased, with those without hypertension or taking antihypertensive medications experiencing smaller drops.
A four-year study of 772 people with pre-hypertension found that early blood pressure treatment can postpone true hypertension by 15.6%. The study suggests that drug treatment interrupted blood-vessel processes that raise blood pressure, reducing the risk of heart disease and stroke.
Researchers found that a low-sodium, high-potassium salt substitute significantly lowered blood pressure in rural China residents at risk of heart complications. The study suggests this simple approach could cut stroke and cardiovascular disease risks.
Researchers found that four major parameters return to normal after one day, and all changes recover within three days. Blood pressure variability is a key predictor of competition time, with low frequency variability being the most significant factor.
A study of 72 children in Ecuador found that prenatal pesticide exposure was associated with higher systolic blood pressure and decreased ability to copy shapes. The effects of prenatal exposure may last into childhood, with stunting also linked to impaired cognitive function.
Researchers studied over 500 pairs of twins, finding that changes in gene expression between ages 14 and 18 accounted for up to one-third of the blood pressure variation by age 18. Novel genetic influences emerged during this period, suggesting new genes play a role in regulating blood pressure.
A community-wide health program in Limburg, Netherlands, reduced the worsening of health status among residents aged 25-70, particularly for BMI and waist circumference. The study found significant differences in systolic blood pressure between the intervention group and a control group.
A study of 470 Dutch men aged 65-84 found that regular cocoa consumption was associated with lower blood pressure and a significantly reduced risk of death from all causes, including cardiovascular disease. The benefits were not attributed to lowering blood pressure alone but may be related to flavan-3-ols and antioxidants in cocoa.
A new genetic test has been developed with a 78% accuracy in predicting individuals with low renin levels and salt sensitivity. The test is based on the number of variations found in salt-regulating genes, with more gene variants associated with bigger health problems.
Researchers examined treatment to maintain blood pressure in patients with orthostatic hypotension (OH) caused by a neurological disease. Pyridostigmine bromide, approved for other uses, showed promise in improving symptoms and reducing standing blood pressure. The medication was found to be beneficial with minimal side effects.
A new study published in Psychophysiology found that mental stress increases blood pressure, which can lead to heart disease. The research used fMRI to correlate changes in brain activity with blood pressure during stress, providing new insights into the physiological effects of mental stress.
A study analyzing data from the INTERMAP study found a significant association between higher vegetable protein intake and lower blood pressure levels. The researchers suggest that amino acids in vegetable proteins may play a role in this effect, and other dietary components like magnesium may also contribute.
A study by the American Society of Plastic Surgeons found that men with high blood pressure after undergoing a facelift had a significantly lower incidence of hematoma. To minimize this risk, patients should have their blood pressure controlled before surgery and manage it with their primary care physician.
A randomized feeding study found that diets partially replacing carbohydrates with protein or monounsaturated fat lowered blood pressure and improved serum lipid levels. These findings suggest that macronutrient substitution can further reduce cardiovascular disease risk in the general population.
Researchers found two biomarkers, sVCAM-1 and NT-proBNP, significantly predict recurrent ischemic stroke risk in patients. High levels of these markers are associated with a 3.6 times increased risk, indicating potential new therapeutic targets for blood pressure-lowering therapies.
Researchers discovered a significant link between a genetic variation in the DRD4 gene and high blood pressure, which could help explain individual risk factors. The study also sheds light on how this gene affects kidney function and blood pressure regulation.
Scientists at University of Cincinnati discover a hormone that regulates blood pressure and is linked to preeclampsia, a leading cause of fetal complications. By understanding how this hormone interacts with the sodium pump, researchers aim to develop a treatment for preeclampsia.
Researchers have discovered that two low-cost diuretics, amiloride and spironolactone, can significantly lower blood pressure in African-American patients. The study's findings suggest that these alternative drugs may be a more effective treatment option for patients who have not responded well to standard therapy.
Researchers develop gene therapy that increases atrial natriuretic peptide production to control blood pressure without severely reducing it. The therapy successfully maintained healthy blood pressure levels for 125 days in mice.
A Canadian study found that job strain increases systolic blood pressure by 2.8 mmHg, while high marital cohesion in the presence of job strain decreases it by 2.5 mmHg over a year. The study suggests people with high job strain and low marital cohesion should see their doctor for a blood pressure check.
African-Americans experience more pronounced cognitive decline with higher blood pressure compared to whites, even among non-demented individuals. The study found significant associations between blood pressure and cognitive performance in African-American subjects, particularly in abstract reasoning and visual organization skills.
Researchers found that estrogen depletion exacerbates diastolic dysfunction and increases blood pressure in rats fed a high salt diet. The study suggests that estrogen may protect against hypertension and renal damage caused by excess salt intake.
Two 'ephedra-free' supplements, Advantra Z and Xenadrine EFX, increased heart rate by an average of 11-16 beats per minute and blood pressure by 7-12 percent. The study calls for further research on the safety and effectiveness of bitter orange-containing supplements.
A study by the Framingham Heart Study found that despite increasing rates of high blood pressure with age, treatment rates for older adults remain low. Seventy-four percent of people aged 80 and older have high blood pressure, but only a minority receive treatment.
A study found that inhaling salt particles causes significant increases in blood pressure, putting factory workers at risk. Wearing protective gear can mitigate this effect.