The combination of aliskiren and valsartan significantly lowers blood pressure in patients with hypertension, with a mean drop of 12.2mm Hg compared to 9.0mm Hg for monotherapy. However, the treatment is limited by potential life-threatening side effects, including hyperkalemia.
A study found that consuming small amounts of dark chocolate daily reduced systolic and diastolic blood pressure without adverse effects. The findings suggest that adopting flavanol-rich cocoa into one's diet may be a promising approach to lower blood pressure in individuals with above-optimal blood pressure levels.
A study by the American Academy of Neurology found that more women than men experience a mid-life stroke between the ages of 45-54. The researchers identified increased waist size and coronary artery disease as predictors of stroke among women in this age group, with no sex differences observed in other age groups.
Patients who experience a significant drop in blood pressure during bypass surgery may be at risk for early difficulties in thinking, learning, and memory. Those with higher pre-surgery blood pressure levels were more likely to have decreased cognitive scores after the procedure.
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Substituting soy nuts for protein sources improves blood pressure and cholesterol levels in postmenopausal women. The study found significant reductions in systolic and diastolic blood pressure, as well as decreased 'bad' cholesterol levels, in women with high blood pressure.
A new international study involving over 10,700 people with high blood pressure found that single-tablet combinations of drugs can bring blood pressure under control for up to 80% of US patients. The six-month treatment period saw a near-doubling of the proportion of patients achieving controlled blood pressure.
A study found that even low levels of physical activity, such as 75 minutes a week, can significantly improve fitness levels and reduce cardiovascular disease risks in postmenopausal women. The research suggests that sedentary adults who struggle to find time for exercise may benefit from even small amounts of physical activity.
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Researchers found that employees who participated in a workplace health program improved their blood pressure control and diabetes management, with significant reductions in absenteeism and workplace accidents. The program's comprehensive wellness system, which included coaching, incentives, and health screenings, was key to its success.
Research suggests that chunky adolescents are headed in the wrong direction regarding cardiovascular health, with increased blood pressure and sodium intake found across all weight categories.
The review of six large-scale clinical trials found that aliskiren was not more effective than existing antihypertensive drugs in controlling blood pressure. The drug's inability to effectively lower blood pressure was attributed to its stimulation of kidney renin secretion, which can counteract its antihypertensive capabilities.
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A Penn State study found that eating pistachios reduced the body's response to stress in individuals with high cholesterol but normal blood pressure. The 3-ounce pistachio diet was most effective in reducing systolic blood pressure and improving vascular relaxation.
A University of Georgia study found that giving commonly prescribed blood pressure medications within 24 hours of a stroke can significantly reduce brain damage. The finding may revolutionize emergency stroke care by adding these medications to clot-busting and blood thinners as front-line treatments.
A study published in Neurology found that blood pressure rates during periodic leg movements rose significantly in people with untreated RLS, increasing cardiovascular risk. The study also showed that age and disease history are key factors contributing to these increased blood pressure changes.
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A meta-analysis of 10 previous studies found that consuming cocoa products reduces systolic and diastolic blood pressure, comparable to the effects of blood pressure-lowering medications. However, drinking tea was not associated with a reduction in blood pressure in any of the trials.
The program, which teaches healthy habits and offers hope for a healthier future, has been successful in lowering diastolic blood pressure, total cholesterol, and LDL cholesterol levels among participants. With a significant drop in systolic blood pressures and blood glucose levels, the program aims to fight childhood obesity.
Researchers found clevidipine to be more effective in controlling blood pressure compared to nitroglycerin and nicardipine. Measuring pro-B-type natriuretic peptide levels can help diagnose cardiac versus pulmonary dyspnea.
Researchers have identified promising new drug combinations that can improve survival rates among patients with severe heart disease. Studies show that using imaging technologies like PET-guided therapy can also help doctors make more accurate decisions about therapies for these high-risk patients.
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A combination of aliskiren and valsartan showed improved blood pressure control compared to individual treatments or placebo. The dual renin system blocking drug combo reduced systolic and diastolic blood pressure, achieving a goal blood pressure of 140/90 mmHg in 49.3% of patients.
New implantable device stimulates body's regulatory systems to control high blood pressure; computerized angioplasty protocol reduces risk of renarrowing and complications after coronary stenting.
A study by the University of Chicago Medical Center found that a specialized chiropractic adjustment can lower blood pressure significantly in individuals with a misaligned Atlas vertebra and high blood pressure. The results showed a decrease equal to taking two blood-pressure drugs at once, with no change in heart rate.
Researchers found that a core clock gene regulates stress response and blood pressure, providing a novel link to the diurnal variation in heart attack risk. The study suggests modifying the molecular clock using drugs could be a treatment for people with high blood pressure.
Researchers at UT Southwestern Medical Center have found that C-Reactive Protein (CRP) directly induces hypertension in mice. The study, which manipulated CRP levels in mice with an engineered gene, showed a direct correlation between CRP and blood pressure elevation.
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Adolescents with parents in the military experience increased stress and physiological changes during wartime, including higher blood pressure and heart rates. Researchers found that these effects were particularly pronounced in children of deployed parents.
Researchers found a strong association between high blood pressure during pregnancy and increased coronary calcification later in life. Women who developed hypertension during pregnancy were at a 57% higher risk of cardiovascular disease, including type-2 diabetes and heart disease.
A recent study of 4,500 American adolescents found that sedentary activities and higher body mass index (BMI) are associated with higher systolic blood pressure. Encouraging adolescents to reduce their sedentary activity may improve their blood pressure and lower their later risk of cardiovascular disease.
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US physicians tend to start treatment sooner and are more aggressive in controlling blood pressure, with 63% of patients having their blood pressure under control. However, vast room for improvement exists, with less than two-thirds of patients reaching guideline-set goals.
Individuals with diagnosed hypertension in the US have lower blood pressure readings and better control compared to those in five Western European countries. The study found that treatment thresholds are more aggressive in the US, resulting in higher rates of hypertension control.
A new study finds that tanshinone IIA, an active ingredient in the Chinese herb danshen, significantly reduces blood pressure in hamsters. The treatment also enhances expression of endothelial nitric oxide synthase and increases production of nitric oxide.
A study found that switching patients to more affordable cholesterol and blood pressure medications saved the UK's National Health Service £26,000 annually. The switch was made without adverse events and was successful for the majority of patients.
Research suggests that inflammatory genes may play a key role in salt-sensitive hypertension, which affects nearly one-third of Americans. The study investigates the connection between stress, inflammation, and sodium handling, with potential therapeutic implications for high blood pressure management.
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A $1.7 billion North American study aims to answer whether reopening narrowed kidney arteries benefits patients. Researchers will compare medical management with medicines coupled with stents, stainless steel scaffolds inserted into blood vessels.
Researchers found that genetic variations impact blood pressure differently in men and women, suggesting a need to consider gender when diagnosing and treating hypertension. The study identified six genes with varying frequency of variation between sexes and extreme blood pressure levels.
A device implanted in US patients with severe hypertension shows significant reduction in blood pressure, averaging 22mmHg systolic and 18mmHg diastolic. The Rheos System activates the body's baroreflex system to lower blood pressure through electrical stimulation.
Researchers found that pioglitazone reduced carotid artery intima-media thickness by .001 millimeters and improved blood glucose control, while increasing HDL cholesterol levels. These findings suggest pioglitazone may be a new approach to further reduce cardiovascular risk in patients with type 2 diabetes.
A study found that heart failure patients with higher systolic blood pressures had lower death rates compared to those with lower pressures. Lower systolic pressures may indicate more advanced disease and a poorer prognosis.
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Researchers highlight the importance of understanding risk factors for heel ulcers, which are often linked to peripheral neuropathy and diminished vascular function. Additionally, studies demonstrate the effectiveness of lateral-wedge insoles in relieving pain and stiffness in people with knee osteoarthritis. The study also explores th...
Hydrogen sulfide gas induces a state of suspended animation in mice, maintaining normal blood pressure, which may help treat critically ill patients. The gas reduces metabolic rate and body temperature, but surprisingly does not decrease blood pressure.
A new multicenter research consortium, called Protocolized Care for Early Septic Shock (ProCESS), is beginning a large-scale study to determine whether specific interventions can halt the progression to severe sepsis and septic shock. The project aims to establish standard procedures to diagnose and treat sepsis in emergency departments.
A University of Alberta study found that walking alone is unlikely to produce marked health benefits compared to more intense exercise programs. Regular moderate activity and occasional vigorous periods are crucial for optimal health outcomes.
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A recent study reveals that older women have as many risk factors for heart disease as men in their 60s and more by their 70s. The research, led by USC demographers, shows a shift from previous decades where older men were at greater risk.
A new study published in the Lancet found that aggressive treatment to lower blood pressure significantly reduces the risk of stroke and heart attack. The research, which involved over 160,000 individuals in 50 countries, highlights the importance of driving blood pressure down to very low levels rather than choosing specific medications.
A study published in the Journal of Gerontology found that higher blood pressure is associated with a decline in walking ability in older persons. The research, led by Dr. Raj Shah, suggests that controlling blood pressure may help prevent gait difficulties in older adults.
A study compares kidney transplant outcomes in the US and Spain, finding similar one-year and five-year graft survival rates for heart-beating and non-heart-beating donors. Living kidney donors also experience higher blood pressure years after donation, highlighting implications for informed consent and follow-up care.
A Mayo Clinic study found that patients with widely fluctuating blood pressure during the first three hours in the emergency room were much less likely to survive more than 90 days after a stroke. The study suggests that managing blood pressure acutely after ischemic stroke is crucial to improve survival rates.
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A study found that increased nighttime blood pressure may be associated with a higher risk of developing congestive heart failure. Analyzing data from 951 elderly men, researchers discovered that a 9–mm Hg increase in nighttime ambulatory diastolic blood pressure and non-dipping blood pressure patterns were significant predictors of CHF.
Researchers found that healthy black girls experience a significant drop in estrogen levels during stress, leading to increased blood pressure and elevated risk of heart disease. In contrast, white teens maintain consistent estrogen levels, reducing their blood pressure response to stress.
Researchers investigate sodium channel genes to identify genetic predictors of hypertension and develop screening methods for high blood pressure in the general population. A study involving 300 healthy youth will measure sodium handling after environmental stress and analyze their genes to correlate with impaired natriuresis.
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Researchers found that a combination of beta-blockers, calcium antagonists, and ACE inhibitors effectively lowers blood pressure in Hispanic patients while reducing their risk of developing diabetes. The study showed a 19% increased risk of diabetes in Hispanic patients but a 15% decreased risk with the verapamil-trandolapril strategy.
A new study found that a nighttime breathing mask can significantly reduce blood pressure in individuals with moderate to severe sleep apnea. The researchers also discovered that correcting oxygen levels alone may not be enough to lower blood pressure.
A study using RESPeRATE, a device-guided paced breathing system, found significant reductions in blood pressure and peripheral resistance in hypertensive patients. The treatment group showed a greater systolic BP reduction correlated with the total time spent in slow breathing.
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The World Hypertension League is calling for better awareness of high blood pressure patients reaching the internationally-recognised goal of 140/90mmHg or lower. Despite this, around 50-70% of people with high blood pressure worldwide remain above this goal, leaving them at significant risk of cardiovascular disease.
Scientists used RNA interference to block a mineralocorticoid receptor, which signals the body to absorb sodium and water into the bloodstream. The treatment kept blood pressure from worsening but did not eliminate it, and significantly reduced kidney damage in rats.
A University of Chicago study found that lonely individuals have significantly higher blood pressures than non-lonely people, even after accounting for other factors. The researchers discovered a strong link between loneliness and increased blood pressure in aging adults, with the greatest differences observed among older participants.
A recent study by UC Davis researchers found that grape seed extract can significantly reduce blood pressure in individuals with metabolic syndrome. The one-month study involved 24 patients, who experienced an average drop of 12 millimeters in systolic and 8 millimeters in diastolic blood pressure.
A study of 347 patients who underwent bariatric surgery between 1992 and 2001 found a significant reduction in blood pressure 18 months post-surgery. Systolic and diastolic blood pressures decreased, with those without hypertension or taking antihypertensive medications experiencing smaller drops.
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The study found that patients with extreme obesity who underwent gastric bypass surgery experienced significant reductions in blood pressure. The majority of these patients were able to reduce or eliminate their blood pressure medications after surgery, while those with normal blood pressure showed no significant changes.
A four-year study of 772 people with pre-hypertension found that early blood pressure treatment can postpone true hypertension by 15.6%. The study suggests that drug treatment interrupted blood-vessel processes that raise blood pressure, reducing the risk of heart disease and stroke.
Researchers found that a low-sodium, high-potassium salt substitute significantly lowered blood pressure in rural China residents at risk of heart complications. The study suggests this simple approach could cut stroke and cardiovascular disease risks.
A study of 72 children in Ecuador found that prenatal pesticide exposure was associated with higher systolic blood pressure and decreased ability to copy shapes. The effects of prenatal exposure may last into childhood, with stunting also linked to impaired cognitive function.
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Researchers found that four major parameters return to normal after one day, and all changes recover within three days. Blood pressure variability is a key predictor of competition time, with low frequency variability being the most significant factor.