Scientists at University of Cincinnati discover a hormone that regulates blood pressure and is linked to preeclampsia, a leading cause of fetal complications. By understanding how this hormone interacts with the sodium pump, researchers aim to develop a treatment for preeclampsia.
Researchers discovered a significant link between a genetic variation in the DRD4 gene and high blood pressure, which could help explain individual risk factors. The study also sheds light on how this gene affects kidney function and blood pressure regulation.
Researchers have discovered that two low-cost diuretics, amiloride and spironolactone, can significantly lower blood pressure in African-American patients. The study's findings suggest that these alternative drugs may be a more effective treatment option for patients who have not responded well to standard therapy.
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Researchers develop gene therapy that increases atrial natriuretic peptide production to control blood pressure without severely reducing it. The therapy successfully maintained healthy blood pressure levels for 125 days in mice.
A Canadian study found that job strain increases systolic blood pressure by 2.8 mmHg, while high marital cohesion in the presence of job strain decreases it by 2.5 mmHg over a year. The study suggests people with high job strain and low marital cohesion should see their doctor for a blood pressure check.
African-Americans experience more pronounced cognitive decline with higher blood pressure compared to whites, even among non-demented individuals. The study found significant associations between blood pressure and cognitive performance in African-American subjects, particularly in abstract reasoning and visual organization skills.
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Researchers found that estrogen depletion exacerbates diastolic dysfunction and increases blood pressure in rats fed a high salt diet. The study suggests that estrogen may protect against hypertension and renal damage caused by excess salt intake.
Two 'ephedra-free' supplements, Advantra Z and Xenadrine EFX, increased heart rate by an average of 11-16 beats per minute and blood pressure by 7-12 percent. The study calls for further research on the safety and effectiveness of bitter orange-containing supplements.
A study by the Framingham Heart Study found that despite increasing rates of high blood pressure with age, treatment rates for older adults remain low. Seventy-four percent of people aged 80 and older have high blood pressure, but only a minority receive treatment.
A study found that inhaling salt particles causes significant increases in blood pressure, putting factory workers at risk. Wearing protective gear can mitigate this effect.
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Researchers found that cobblestone walking improved balance, mobility, and reduced blood pressure in older adults. The activity, rooted in traditional Chinese medicine, has been shown to be therapeutic and can be done at home with manufactured mats.
A new scoring system, ABCD, predicts the risk of stroke within 7 days of a 'mini-stroke'. The system helps identify high-risk individuals who require emergency investigation and treatment. Most strokes in the UK occur in patients who have been referred to hospital clinics but not seen.
African-American patients have a higher rate of increased heart weight, or left-ventricular hypertrophy, than whites regardless of their differences in body fat and overall body composition. Elevated blood pressure is the best indicator of why African-Americans in the study had a higher rate of left-ventricular hypertrophy.
Benicar-based treatment algorithms significantly reduced mean systolic blood pressure in Stage 2 hypertensive populations. In Stage 1 patients, 89% reached the aggressive blood pressure goal of less than 130/85 mmHg.
A new combination of irbesartan and hydrochlorothiazide reduced systolic blood pressure by an average of 21.5 points in 77% of patients, with 83% achieving acceptable diastolic blood pressure levels. The study included diverse patient groups and showed significant results.
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A new analysis found that a non-drug device-guided slow breathing treatment reduced the white-coat effect by ~80% in patients, compared to ~40% for controls. The treatment was also effective across different patient groups, including pre-hypertensives and resistant hypertensive patients.
Researchers found that non-dippers had higher fasting glucose levels and were more likely to develop diabetes. Monitoring glucose levels is crucial for these patients to prevent cardiovascular problems.
Older adults with mild hypertension did not experience significant reductions in blood pressure through exercise alone, according to a new study. However, those who lost fat and gained muscle showed more substantial benefits.
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Researchers at Yale University identified a novel human kidney protein called renalase that regulates both heart contraction and blood pressure. The protein is a strong candidate for easily administered treatment of advanced kidney and cardiovascular disease.
Researchers identified a new protein called renalase, which regulates heart rate and blood pressure. Reduced levels of renalase have been linked to increased cardiovascular risk in patients with end-stage kidney disease.
The Rheos System uses low-level electrical stimulation to activate the brain's control mechanisms, promoting fluid excretion and reducing blood pressure. The device has shown promise in lowering blood pressure in patients who have not responded to medications.
Researchers found no causative MEF2A mutations in patients with premature coronary heart disease, contradicting previous findings. The study suggests that another gene may be responsible for the heart disease, casting doubt on the role of MEF2A in CAD.
Research reveals kidneys and other systemic tissues have distinct roles in controlling blood pressure, challenging the dominant view that kidneys play a central role. The findings suggest that maximal efficacy of hypertension drugs requires complete blockade of receptors in both kidney and outside of kidney.
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Researchers are investigating early changes in the heart's function that may lead to congestive heart failure. Studying 15-18-year-olds on video games and measuring blood pressure, they hope to identify factors triggering diastolic dysfunction.
Research reveals employees with diabetes can be valuable workers in a favorable environment. The burden of fatigue is largely determined by the individual's self-management capabilities and outlook on their disease and work situation.
A 15-year study in rural Greece found that living in a mountainous area was associated with lower death rates and healthier heart profiles compared to lowland areas. Higher blood lipids and blood pressure were linked to increased risk, but other protective factors may be at play.
A Mayo Clinic study found that spit tobacco use can cause dramatic increases in heart rate and blood pressure, blunting the body's natural protective mechanisms. This raises concerns for both short-term users and individuals with established heart disease, suggesting a link to long-term cardiovascular risks.
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A Medical College of Georgia study found that individuals with higher lean body mass can better regulate their blood pressure in response to stress. This is because fitness allows the body to efficiently excrete sodium, which helps lower blood pressure back to normal.
A study found that the renin-angiotensin system may be associated with physical function in older adults, and that ACE gene variants can affect exercise response. Additionally, researchers discovered a potential link between this system and cognitive impairment, suggesting new avenues for intervention.
The study found that amlodipine reduced the risk of cardiovascular events by 31% compared to placebo, while enalapril showed no significant reduction. A subset of patients also showed slowing of progression of coronary artery atherosclerosis with amlodipine.
A multi-center randomized controlled study found that 45 minutes of weekly self-treatment with RESPeRATE significantly reduces systolic blood pressure, with greater reductions in medicated and non-medicated patients. The device's effectiveness was correlated with slow breathing time, making it easy to use at home.
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A study of 162 Japanese patients with mild to moderate Alzheimer's disease and high blood pressure found that brain-penetrating ACE inhibitors slowed cognitive decline. The medications declined thinking and memory skills by only 0.6 points, compared to 4.9 points for calcium channel blockers.
African-American communities benefit from education programs that lower blood pressure readings. Researchers also found that changing sleeping positions can alter blood pressure, with stomach-lying positions leading to a significant drop in systolic blood pressure. Furthermore, impaired kidney function significantly increases the risk ...
Researchers warn of potential cardiovascular risks associated with the use of modafinil, a new alertness medication. A low-salt diet has also been shown to protect arteries in people with resistant hypertension, according to the study.
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Researchers at Mayo Clinic found that pyridostigmine improved patients' standing blood pressure and reduced symptoms without elevating blood pressure while lying down. The study showed significant results in reducing the need for other medications, particularly in those over age 70 with common causes like diabetes and Parkinson's disease.
A 20-year study found that high blood pressure is associated with a decline in cognitive function in both younger and older adults. The research emphasizes the importance of reducing blood pressure levels in younger individuals to prevent cognitive decline.
A study led by Mount Sinai School of Medicine researchers found that imidazole-4-acetic acid-ribotide may be a primary cause of high blood pressure and a molecular link to diabetes. The molecule binds to receptors in the brain, leading to elevated blood pressure, which can also impair insulin release.
A recent study published in the Journal of Dental Education found that nearly half of patients with high blood pressure at a dental clinic had never been diagnosed. The researchers advocate for regular blood pressure screening in dental offices, which could help identify hypertension early and prevent related health issues.
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Yale researchers found strong clinical evidence to support treating systolic blood pressure of at least 160 mm Hg in older adults. Treatment decisions should prioritize patient preferences and tolerance of therapy due to limited evidence on benefits.
Researchers found that angiotensin-(1-7) significantly slows the growth of three human lung cancer cells in laboratory tests. The hormone is thought to regulate cell growth by reducing rapid proliferation and increasing cancer cell death, offering a potential new treatment approach for lung cancer.
A study of 676 individuals with PAD found that those with lower ABI levels had greater declines in walking endurance and speed. Leg symptoms, particularly pain on exertion, also predicted rates of functional decline.
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Researchers at Vanderbilt University Medical Center found that chronic high-dose consumption of Vioxx raises blood pressure and increases the risk of serious heart problems. A substantial number of patients continue to receive high doses of the drug, despite evidence suggesting its potential harm.
A study of 5,115 young adults found that those who react to psychological stress with spikes in blood pressure are more likely to develop high blood pressure in their 40s. The research suggests that assessing blood pressure changes in response to stress may be a useful tool for determining future risk.
The VALUE trial found no difference in cardiac disease between valsartan and amlodipine, but patients on valsartan had lower rates of hospitalization for heart failure and type 2 diabetes. Early blood pressure control was associated with improved cardiovascular outcomes.
The study found that BENICAR and Benicar HCT helped patients reach aggressive blood pressure goals, with nearly 69.3% achieving less than or equal to 130/85 mmHg after 16 weeks. Additionally, BENICAR was found to be more effective in reaching blood pressure goals compared to other ARBs like Cozaar and Diovan.
The US Preventive Services Task Force recommends against routine ovarian cancer screening due to no evidence that it reduces mortality. In contrast, they support regular eye exams for children under 5 to detect amblyopia and other causes of visual impairment. Early detection can improve visual acuity and prevent long-term harm.
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New guidelines from Thomas Jefferson University offer more precise classification of blood pressure in children and adolescents based on gender, age, and height. Pediatricians are encouraged to recommend diet, exercise, and weight control counseling for children with prehypertension.
A recent study found that average blood pressure levels among American children and teenagers have increased over the past two decades. The new clinical practice guidelines will provide updated recommendations for lifestyle and drug therapies to address this trend.
A study found significant increases in blood pressure levels among children and adolescents between 1988-1994 and 1999-2000, with systolic levels increasing by 1.4mmHg and diastolic levels by 3.3mmHg. The researchers suggest that effective primary and secondary hypertension prevention programs are needed to address this trend.
A new study has found a significant link between caffeine consumption and increased blood pressure in black adolescents. Adolescents who drank the most caffeinated beverages had higher systolic pressures, with black adolescents showing a greater impact. The researchers suggest that further research is needed to explore this relationship.
Researchers found that a blood pressure-lowering regimen in stroke patients can stop or delay further ischemic brain damage. The study showed that patients who received the medication had significantly fewer new white matter lesions compared to those who took placebo.
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Researchers investigate protein regulators of inflammation and hypertension, aiming to find direct cause-and-effect relationship between the two. The study could lead to new targets for treating high blood pressure, a major risk factor for heart disease.
A new study published in the American Journal of Hypertension demonstrates that 15 minutes of daily RESPeRATE treatment significantly reduces home blood pressure in both medicated and non-medicated patients. The study also shows high patient compliance, with many patients continuing treatment after the trial ended.
Researchers found that repeated pregnancies in rats increased blood pressure response to stress and phenylephrine infusion, due to enhanced total peripheral resistance. Vascular sensitivity was also altered, with reduced compliance and sensitivity to phenylephrine.
Researchers found that radiation damages key receptors impacting blood pressure, leading to faulty repair of DNA breaks and cell death. A new study examines three cases where symptomatic baroreflex failure occurred as a late consequence of neck irradiation.
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Researchers found that exercise-induced high blood pressure may be caused by cells failing to relax and expand blood vessels. This impairment can be a common factor among various risk factors for heart disease, including aging, menopause, and diabetes.
The UPMC Community Medicine initiative improved HbA1c levels by 0.83 percent and reduced blood pressure and cholesterol below target ranges in a large proportion of patients. Physician compliance with evidence-based guidelines was significantly increased through data tracking and education.
A study found that 156 inner-city black adolescents who practiced transcendental meditation twice daily for four months lowered their daytime blood pressures, with an average drop of 3.5 millimeters in systolic pressure and 3.4 millimeters in diastolic pressure.
A gain-of-function mutation in the KCNMB1 potassium channel subunit is associated with a lower prevalence of diastolic hypertension. The beta1 subunit of the Ca2+-sensitive K+ channel protects against hypertension, as outlined in an accompanying commentary.
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A study of 4,939 elderly patients with hypertension found that home blood pressure testing was more accurate than office tests in predicting cardiovascular events. Home blood pressure testing showed a 17.2% increased risk of cardiovascular events for each 10-mm Hg increase in systolic blood pressure.