A debate between world-leading experts reveals conflicting views on blood pressure control, with some arguing the kidneys play a key role and others pointing to the brain's influence. The discussion highlights major issues in blood pressure control and will guide future studies.
A new study published in Journal of Human Hypertension demonstrates RESPeRATE's effectiveness in reducing office systolic blood pressure by -10.0 mm Hg in non-insulin dependent diabetics, with a full 88% of patients experiencing significant blood pressure reduction.
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A systematic review of eight trials found that lowering blood pressure with medication reduced cardiovascular complications, all-cause mortality, and cardiovascular deaths among dialysis patients. The protective effects were similar across different drug classes and were well-tolerated.
A combination of two antihypertensive drugs lowers the risk of kidney disease in diabetics, even among those with normal blood pressure. The study found a 21% lower rate of kidney disease events in patients receiving the combination therapy.
A study by UC Irvine researchers found that individuals with high systolic and low diastolic blood pressures are at a greater risk of heart attack and stroke. The combination of these two blood pressure components is a superior predictor of future adverse cardiovascular events.
Researchers have identified two common gene variants associated with increased blood pressure levels, which may lead to new therapies. The study, published in Nature Genetics, found that these variants affect proteins involved in cardiovascular response to stress, influencing blood pressure levels.
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A study of 1900 Chinese participants found that individuals with metabolic syndrome are more sensitive to salt intake, leading to increased blood pressure responses. This finding suggests that reducing sodium intake could be a crucial component in managing blood pressure for patients with multiple risk factors for metabolic syndrome.
A study published in Hypertension: Journal of the American Heart Association shows that high blood pressure control increased significantly in England between 2003 and 2006. In 2006, 53% of women and 52% of men achieved control, with awareness and treatment rates also increasing.
Researchers at Louisiana State University Health Sciences Center have found a potential new target for hypertension treatment in the brain's Angiotensin-converting enzyme 2 (ACE2). By blocking one of its receptors, AT1Rs, ACE2 activity increased, normalizing impaired baroreceptor reflex function and blood pressure.
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A new study found that increasing potassium intake and reducing sodium consumption can significantly lower the risk of cardiovascular disease. Researchers analyzed 24-hour urine samples from over 2,900 participants and discovered a strong correlation between the ratio of sodium-to-potassium in urine and cardiovascular disease.
A French study of 8801 elderly participants found significant seasonal variations in systolic and diastolic blood pressure according to outdoor temperature. The authors advise careful monitoring and antihypertensive treatment during extreme temperatures, particularly in the elderly, who are at higher risk of cardiovascular events.
A new study published in the American Journal of Clinical Nutrition suggests that reducing salt intake can have cardioprotective effects beyond lowering blood pressure. The research found benefits for people with normal blood pressure and those who are overweight or obese, starting as early as a few weeks after sodium reduction.
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A study found that elderly individuals have a higher risk of hypertension during colder months, with average systolic blood pressure 5 millimeters of mercury higher in winter than summer. Blood pressure decreases over time are also strongly correlated with outdoor temperature, particularly in participants aged 80 and older.
Researchers at OHSU School of Dentistry discovered a molecule, BDNF, that plays a critical role in the development and regulation of blood pressure. The finding may contribute to the prevention of Sudden Infant Death Syndrome (SIDS) and high blood pressure.
A new study by Yale University researchers identifies a mechanism behind stroke in patients with sleep apnea, revealing impaired cerebral autoregulation and increased risk of death. Symptoms of sleep apnea include loud snoring, pauses in breathing and excessive daytime fatigue.
A recent study published in JAMA found that skipping one hour of sleep per night can increase the risk of coronary artery calcification, a precursor to cardiovascular disease. The study, which followed 495 healthy volunteers, found that those who slept less than five hours per night were more likely to develop calcified arteries.
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A study found that continuous blood pressure monitoring can help predict heart disease and related deaths among individuals with treatment-resistant hypertension. In contrast, blood pressure readings taken in a medical office do not appear to predict future heart risks.
Young African-American men have higher central blood pressure and stiffer blood vessels compared to their white counterparts, indicating early signs of hypertension. Central blood pressure is a key factor in detecting the problem, suggesting that it may be developing undetected in young African-American men.
A study found that pay for performance schemes improved coronary heart disease management across ethnic groups, with fewer disparities in care. The scheme also led to increased blood pressure control and statin prescriptions among South Asians and whites, but not among blacks.
A European study found that 24% of participants had high blood pressure, with 56% of those unaware of their condition. Less than half of aware individuals had controlled blood pressure. The study suggests a call for better hypertension management and prevention.
A new study finds that air pollution has a significant impact on heart health, with personal exposure leading to increased blood pressure and systolic blood pressure. Community-level exposure is also associated with impaired blood vessel functioning, potentially contributing to sudden heart attacks, strokes, and heart failure.
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A study by University of Rochester Medical Center researchers found that black Americans have a higher risk of death from heart disease and stroke due to uncontrolled blood pressure. The researchers concluded that reducing mean blood pressure among blacks could prevent 5,480 deaths annually.
A new UK study found that black and south Asian people are less likely to benefit from doctors' interventions to reduce their blood pressure. The study, which looked at over 8,800 patients with high blood pressure, found significant differences in treatment outcomes between white, black, and south Asian groups.
A recent study published at the American Society of Nephrology's annual meeting found that low potassium levels are strongly linked to high blood pressure in African Americans. The research suggests that consuming more potassium-rich foods, such as fruits and vegetables, may help lower blood pressure.
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A study led by Ercan Ok found that overnight hemodialysis reduced mortality rates by 78% and improved blood pressure control, appetite, weight gain, and cognitive functioning among patients. The results suggest longer dialysis regimens as a promising alternative to addressing high risk of death among dialysis patients.
A new University of Michigan Cardiovascular Center study suggests that grapes can lower blood pressure and signs of heart muscle damage, and improve heart function in lab rats. The effect is thought to be due to the high level of phytochemicals - naturally occurring antioxidants - found in grapes.
Hydrogen sulfide is produced in the endothelial lining of blood vessels and regulates blood pressure by relaxing blood vessels. The discovery has potential applications for designing drug therapies to enhance its formation as an alternative to current hypertension treatments.
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Researchers will examine genomes of 4,000 participants in the CARDIA Study to determine how genes influence rising blood pressure with age. The study aims to discover pathways for targeted therapeutic intervention and could lead to new treatments for cardiovascular disease.
The study found that liraglutide improved blood glucose control compared to glimepiride, with significant reductions in HbA1c levels. Participants receiving liraglutide also experienced weight loss and decreases in systolic blood pressure, making it a promising treatment for type 2 diabetes.
A study found that an audio relaxation program lowered blood pressure more than listening to Mozart music in a group of elderly people with high blood pressure. The program used binaural sound and guided relaxation techniques to lower systolic blood pressure by 6.4% compared to a 5% reduction from Mozart music.
Researchers found no significant differences in adverse events or outcomes between patients who received antihypertensive treatments and those who didn't. Patients requiring blood pressure lowering therapy had more severe strokes and higher blood glucose levels, but still benefited from clot-busting treatment.
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Low-birth-weight children may develop hypertension later in life, and measuring blood pressure is crucial to identify this condition early. Automated devices might overstate systolic blood pressure, so manual methods are recommended to confirm results.
A new study found that rapid weight gain in early childhood is associated with higher systolic and diastolic blood pressure in adulthood. The research, published in the American Heart Association journal, suggests that changes in post-natal weight gain and childhood weight gain are linked to small but significant increases in blood pre...
The TRANSCEND study found that telmisartan modestly reduced the outcome of cardiovascular death, heart attack, stroke, and hospitalization for heart failure. Additionally, fewer patients receiving telmisartan were hospitalized for any cardiovascular reason compared to placebo.
The TRANSCEND study enrolled nearly 6,000 people worldwide who are intolerant to ACE inhibitors and found that telmisartan reduced the outcome of cardiovascular death, heart attack, or stroke by a significant 13% compared to placebo. Fewer patients receiving telmisartan were hospitalized for any cardiovascular reason.
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A study by Baylor College of Medicine found that reducing uric acid levels in teens with high blood pressure lowered blood pressure to normal in most cases. Allopurinol, a medication typically used for gout, showed promise as a potential treatment for high blood pressure.
Women who don't drink coffee can experience a significant caffeine boost, improving mental alertness and heart rate, according to new research. The study found that consuming a large cup of coffee had more than enough caffeine to induce these changes.
Researchers found that teenagers with low sleep efficiency and short sleep duration are at a higher risk of elevated blood pressure and pre-hypertension. The study suggests that optimizing sleep quality is essential for preventing high blood pressure and other health problems in adolescents.
A new study suggests that ventilator-induced lung injury still occurs even with lower breath volumes, highlighting the need for more accurate assessments of lung stress and strain. The researchers recommend routine assessment of esophageal pressure and lung volumes to improve patient outcomes.
A study explores how daily stress affects blood pressure regulation and how genetics, obesity, and oxidative stress contribute to this process. The research aims to develop personalized treatments by identifying factors that make individuals respond differently to stress and therapy.
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A recent study published in Diabetes Care found that losing weight soon after a type 2 diabetes diagnosis can lead to better blood pressure and blood sugar control. The study followed over 2,500 adults with type 2 diabetes for four years and showed that those who lost weight were up to twice as likely to achieve their targets.
A new OSU study finds that exposure to bad air can significantly spike blood pressure in those already predisposed to high blood pressure. Researchers exposed rats to everyday human-breathed pollutants and observed a direct link between air pollution and cardiovascular disease.
Research found that exhausted individuals experience larger blood pressure increases when attempting tasks, even if they perceive success as achievable. Chronic fatigue can amplify effort and lead to elevated blood pressure, increasing the risk of hypertension and heart disease.
A new online care program for hypertension has shown promising results, nearly doubling the percentage of patients with controlled blood pressure. The 'e-BP' study used web-based care and at-home blood pressure checks to improve treatment outcomes.
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A study by Johns Hopkins Bloomberg School of Public Health researchers found a consistent relationship between childhood blood pressure levels and adult blood pressure. Children with elevated blood pressure often grow up to become adults with elevated blood pressure.
A study published in Nutrition Research shows Pycnogenol improves diabetes control and reduces antihypertensive medications. The extract lowered blood sugar, LDL cholesterol, and blood pressure in patients with type II diabetes, suggesting it may serve as a potent adjunct to prescription medications.
A special diabetes care package for UK residents of south Asian ethnic origin has delivered some benefits, including reduced blood pressure and cholesterol levels. However, improving glycaemic control remains a major challenge, and further measures are needed to address health inequalities in this population.
A study found that even when patients with diabetes present with high blood pressure, there's only a 50-50 chance of receiving treatment. Uncertainty about the patient's blood pressure and other medical issues contribute to this 'clinical inertia'. More systematic guidelines for monitoring blood pressure in people with diabetes are needed
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The milk-derived dietary supplement AmealPeptide has been shown to significantly reduce daytime ambulatory systolic blood pressure by 3.6 mmHg and 24-hr systolic blood pressure by 6.2 mmHg in two placebo-controlled trials, confirming its safety and efficacy for patients with Stage I and Stage II hypertension.
Researchers at Thomas Jefferson University discovered that a protective heart failure protein also regulates blood pressure. Lowering this protein's levels in animal models increased blood pressure. The study suggests S100A1 could be a novel therapeutic target for treating hypertension and heart failure.
A study at the American Heart Association’s Scientific Forum on Quality of Care and Outcomes Research in Cardiovascular Disease and Stroke found that focused measures improved high blood pressure control among veterans. The proportion of patients reaching their blood pressure goal increased from 61.8% to 64.3%, with an estimated 1,349 ...
Despite widespread awareness of high blood pressure's dangers, a Stanford study found major shortfalls in screening, treatment, and control of the disease even with doctor care. Only 39% of treated patients achieved recommended blood pressure levels, highlighting the need for increased routine screenings and personalized treatment plans.
Researchers have identified a role for hydrogen sulphide in regulating blood pressure, which works by relaxing vascular tissue and improving blood flow. A slow-releasing H2S donor molecule has been synthesised to study the effects of naturally produced H2S in the body.
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Research by Johns Hopkins Medicine found that African-American patients with chronic kidney disease continue to lose kidney function despite strict blood pressure control. The study suggests that treating CKD in this population may require a more comprehensive approach, considering other factors beyond just blood pressure.
A University of Illinois study found that eating two CocoaVia dark chocolate bars daily lowered total cholesterol by 2% and LDL cholesterol by 5.3%. The drop in cholesterol numbers is attributed to plant sterols added to the bar and flavanols found in dark chocolate.
A large randomized drug trial found statins significantly reduce systolic and diastolic blood pressure, contributing to a reduced risk of stroke and cardiovascular events. The study involved 973 participants taking either simvastatin or pravastatin or a placebo for six months.
Research found people with high blood pressure are up to 40% less likely to have a headache or migraine compared to those with healthier blood pressure rates. Higher pulse pressure was linked to reduced headache and migraine frequency in both men and women.
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Researchers found that statins can modestly reduce systolic and diastolic blood pressure in individuals with hypertension. The study showed a significant decrease in blood pressure at six months of treatment, but not at one month.
A clinical trial found that patients with diabetes who reduced their blood pressure and LDL-cholesterol to below standard target levels had a greater decrease in carotid artery wall thickness, but no significant difference in cardiovascular disease events. Targeted treatment of these conditions improved surrogate measures of cardiovasc...
A three-year study found that participants with type 2 diabetes who lowered their LDL cholesterol and systolic blood pressure levels below current targets experienced a partial reversal of hardening of the arteries. The results suggest that aggressively managing these risk factors can help prevent heart disease in adults with diabetes.