Articles tagged with Disease Control
Researchers discovered antibiotic-resistant bacteria can travel from the gut to the lungs in a patient, highlighting the importance of preventing pathogenic bacteria from translocating to vital organs. The study's findings suggest eliminating resistant bacteria from the gut microbiome could help prevent serious infections.
The American College of Physicians recommends policies to improve healthcare access and quality for incarcerated patients, including adequate funding and timely access to necessary services. The organization also supports treating substance use disorders as an alternative to incarceration.
A recent study found that MRI-guided adaptive radiation therapy, also known as SMART, has shown promising safety and patient outcomes data for treating locally advanced and borderline resectable pancreatic cancer. The study, led by Henry Ford Health, reported no incidence of acute grade 3 or higher gastrointestinal toxicity, with preli...
A new study from Mount Sinai Hospital finds a strong association between age-related macular degeneration and severe forms of heart disease, including heart failure, heart attacks, and stroke. The study highlights the importance of increased screening for eye disorders to diagnose undetected heart disease.
A 30-year follow-up study of patients with early breast cancer found that radiotherapy does not improve overall survival rates after 10 years but reduces the risk of recurrence in the same breast. The study's findings challenge traditional concepts of long-term anti-cancer benefits of radiotherapy.
A study of 3,110 US counties found that residential segregation is associated with increased cancer mortality. The findings highlight opportunities for targeted cancer prevention and control efforts at the county level.
The number of Candida auris cases in the EU/EEA nearly doubled between 2020 and 2021, with 11% of cases having no available information on carriage or infection. Early detection is crucial to prevent the spread of this healthcare-associated pathogen.
Researchers at the University of Ottawa have discovered that patients with electrolyte abnormalities are twice as likely to be diagnosed with an eating disorder. This study analyzed Ontario health data between 2008 and 2020, identifying a potential preventative treatment for approximately 1 million Canadians.
Researchers found that habitat loss and climate-induced food shortages drive pathogen spillover, but preserving and restoring natural habitats can prevent these events. By analyzing data from Australia, the study predicts when viruses like Hendra and Nipah will spill over from bats to humans.
Research finds that increased body weight is associated with higher levels of inflammation, signs of gut permeability, and poorer asthma control. The study suggests that targeting the gut could be an effective treatment target for improving asthma control in patients with obesity. Weight loss may also improve symptoms for these patients.
A new study by Weill Cornell Medicine investigators discovered that error-prone DNA replication and repair may lead to mutations and cancer in individuals with BRCA1 gene mutations. The team identified a faulty DNA repair mechanism called microhomology-mediated break-induced replication (MMBIR) as a key contributor to genomic instabili...
A cross-sectional study found that at least one post-COVID-19 symptom occurred in 59.7% of hospitalized patients and 67.5% of non-hospitalized patients two years after infection. The study suggests that small differences in symptoms at the onset of COVID-19 existed between hospitalization status.
A new study finds that children with severe forms of epilepsy, such as Dravet syndrome, are at high risk of seizures triggered by the flu. The seasonal influenza vaccine is recommended for these children to protect them from complications and prolong their survival.
Research at Tel Aviv University found that high-intensity aerobic exercise increases glucose consumption in internal organs, reducing energy availability for tumors. The study reduced the risk of metastatic cancer in humans and animal models by up to 72%.
A research team developed a vaccine targeting synthetic opioid fentanyl to block its entry into the brain, preventing fatal effects. The breakthrough could have major implications for treating Opioid Use Disorder, with potential relapse prevention capabilities.
A Rutgers study of 86,964 adults with obesity and NAFLD found that bariatric surgery reduced the risk of major cardiovascular events by 49% compared to nonsurgical care. This is significant because heart disease is a leading cause of death in the US, and NAFLD can lead to liver damage and inflammation.
A handheld diagnostic lab developed by UCLA researchers can fully automate pooled testing and detect multiple diseases, reducing costs and usage of scarce supplies. The technology can be easily manufactured, deployed, and performed at a doctor's office or mass testing sites, helping authorities prepare for future pandemics.
A new study published in PLOS Medicine found significant long-term morbidity in children, adolescents, and adults after COVID-19 infection. Children and adolescents are at risk of post-COVID-19 syndrome, with rates of malaise, cough, and headache increased compared to controls.
Between 2000 and 2020, malaria infections fell globally, but a significant increase occurred in sub-Saharan Africa, with 52.4 million pregnancies at risk from Plasmodium falciparum and vivax infection. Control initiatives failed to mitigate this trend.
The West Texas Pharmacology Core laboratory at TTUHSC will focus on two primary areas: drug development and pediatric cancer. The core aims to address obstacles in drug development, including limited pharmacology expertise for small biotech companies and low profitability for pediatric cancer drugs.
Researchers at the University of Helsinki have identified a promising drug candidate, TYK2 inhibitor, for preventing type 1 diabetes. The study found that inhibiting TYK2 expression reduces the destruction of pancreatic beta cells, but may also reduce beta cell production in earlier stages.
A new study confirms that COVID-19 deaths among children and young people are rare, with most fatalities occurring in those with severe neurodisability or compromised immune systems. The analysis of detailed data showed that half of COVID-19 deaths occurred within 30 days of infection.
Researchers investigated Aicardi-Goutières syndrome and found that viral RNA recognition drives uncontrolled interferon production. The immune system mistakenly attacks healthy cells due to the failure of safety mechanisms to distinguish between viral and host genetic material.
A new controlled-release device has been tested at UMass Amherst for its effectiveness in preventing tick bites. The device uses synthetic pyrethroids to create a spatial repellent that alters the behavior of ticks, making them less likely to climb and more likely to detach or fall off. The results show promising promise in reducing th...
A large contact tracing investigation found no secondary cases of monkeypox, informing estimates of exposure risk and postexposure prophylaxis recommendations. The framework's ease of application and cross-setting use has important applications for future infection prevention efforts.
Eczema affects 10-20% of Canadian infants, making it a common condition to manage. Optimally managing atopic dermatitis in infants is crucial, as it impacts the whole family.
Regular use of cholesterol-lowering and diabetes-control drugs may lessen the risk of age-related macular degeneration (AMD) in European populations. The pooled data analysis involved 38,694 participants and showed a 15% lower prevalence of any type of AMD with these medications.
A new study found that a personalized 'precision' testing approach for people with stable chest pain led to more efficient evaluations and improved diagnosis of coronary artery disease. The approach involved assessing cardiovascular risk factors to identify low-risk individuals who may not benefit from further testing.
A customized mindfulness program that incorporates skills like attention control and self-awareness has been shown to lead to lower systolic blood pressure measures in participants. The intervention, which also focuses on health behavior change, is promising as a novel way to improve blood pressure control.
A research team developed a smart mask integrating an ultrathin soundwave sensor that detects breathing, coughing, and speaking sounds. The mask uses machine-learning algorithms to identify respiratory diseases and improve public health by enabling prolonged monitoring.
A new metric estimates cumulative exposure to PFAS chemicals, enabling comparisons across studies and applications. The calculator takes into account patterns of exposure to multiple chemicals, providing a robust tool for biomonitoring and disease assessment.
Researchers from McGill University found that pneumococcal vaccination uptake is low among adults at high risk in Canada. Despite the importance of pneumococcal vaccination to prevent pneumonia and other forms of pneumococcal disease, many people missed opportunities for vaccination.
Amanda Woerman's research aims to disrupt tau misfolding, a common thread in fatal neurodegenerative disorders PSP and CBD. The grant-funded study seeks to test a proof-of-concept gene therapy for these conditions, potentially leading to personalized medicine breakthroughs.
A strain of yeast called Candida auris is causing persistent and difficult-to-treat infections globally. The fungus has been found in hospitals on multiple continents, with cases registered in Denmark, where it has spread through hospital equipment and patient contact.
A UK study found substantial monkeypox transmission before symptoms appear, with 53% of cases occurring pre-symptomatically. The study's findings have important implications for infection control globally and may affect isolation and contact tracing policies.
Researchers at the University of Bonn have identified a new signaling pathway that triggers inflammatory responses in the skin after UV damage. This pathway involves the activation of p38 molecularly modifying NLRP1, a critical switch for inflammation, and initiates the assembly of inflammasomes.
Dr. Ralph L. Sacco, a top stroke neurologist, has advanced understanding of cardiovascular and cerebrovascular diseases through his research on race-related stroke risk. He is recognized for his work in creating targeted stroke prevention programs.
Researchers at MIT have developed a new control system for synthetic genes that can precisely regulate protein production in mammalian cells. The system uses CRISPR proteins to activate target genes and can be tuned to produce specific quantities of proteins, such as monoclonal antibodies.
A specialized triage algorithm, ROCA test, enables earlier stage diagnosis in women deferring preventive surgery, saving NHS costs. The approach results in fewer major surgical interventions and lower risk of wider disease spread.
During the early months of the COVID-19 pandemic, patients with hypertension took less frequent blood pressure measurements and reported higher readings. Blood pressure control worsened due to disruptions in healthcare access, including telemedicine and home monitoring.
Researchers tracked participants for almost 30 years and found a link between past exposure to intimate partner violence and future cardiovascular health. The study suggests that intimate partner violence is associated with a higher risk of heart attacks, strokes, and heart failure hospitalizations.
Research found social vulnerabilities such as poverty and minority status linked to increased cardiometabolic risk during pregnancy. The study analyzed nearly 19 million pregnancies in US counties from 2016-2020 and found that four leading cardiometabolic risk factors were associated with some social vulnerability.
Researchers found a significant increase in heart disease deaths among adults in the US during the COVID-19 pandemic. The study attributed this rise to factors such as lockdowns, lack of physical activity, increased smoking and alcohol use.
Neighborhood walkability is associated with lower cardiovascular disease burden and risk, according to two preliminary studies. The analysis found that even after considering other factors, walkability alone was linked to a 0.1% decrease in cardiovascular disease for each one-point increase in walkability score.
Researchers found that changing gloves and instruments just before closing wounds can prevent as many as 1 in 8 cases of Surgical Site Infection. A new toolkit also helps hospitals prepare for pandemics, heatwaves, and natural disasters.
Researchers evaluated 116 adults' diets and found most underestimated their own diet quality, with a significant gap between self-assessment and objective measurements. The study suggests that people trying to lose weight or health professionals should provide concrete information on improving diet quality.
FAU's nurse-led mobile health unit will provide technology-assisted, culturally aligned health promotion, disease prevention, and primary care services in underserved communities. The project targets high-risk populations with limited access to healthcare.
Mount Sinai researchers created a cloud-based digital framework, Employee Health COVID-19 REDCap Registry, to track employee health data and mitigate COVID-19 spread. The platform reduced case follow-up times from days to hours and helped identify occupational and non-occupational risk factors.
A new experimental drug has shown promising results in treating liver cancer, with two patients experiencing a partial response to the treatment. The drug, NMS-01940153E, targets an enzyme that plays a critical role in cell division and growth, and its side effects are manageable.
Dr. Bibbins-Domingo's research focuses on racial disparities in cardiovascular disease prevention, incidence, and outcomes. She explores long-term effects of early and poorly treated high blood pressure and develops strategies to prevent and manage CVD.
Dr. Paul Muntner receives the 2022 Joseph A. Vita Award for his work on identifying cardiovascular disease risk factors and improving hypertension prevention and treatment. He is recognized for his studies on environmental factors, blood pressure measurements, and African American adults.
Researchers have developed a pioneering gene editing strategy that can repair faulty genes in immune cells, offering new hope for patients with conditions like CTLA-4 insufficiency. The technique uses CRISPR/Cas9 to target and correct the faulty gene, preserving important regulatory mechanisms.
Researchers found that sapanisertib can kill the malaria parasite at several stages during its life cycle, including in the liver and red blood cells. The study's findings offer new hope against a disease that kills over half a million people annually.
Researchers found a significant association between NTM infection and increased mortality in patients with end-stage renal disease. Early diagnosis and treatment may improve survival. NTM can cause nonspecific symptoms like fever and weight loss, and patients with compromised immune systems are at higher risk.
Researchers developed a small peptide that can directly kill bacteria and trigger plant defense tactics to prevent diseases like almond leaf scorch. The treatment significantly reduces pathogen population and disease symptoms, making it a promising approach for sustainable crop protection.
A phase II trial suggests that radiation can reduce painful complications and hospitalizations, and possibly extend overall survival in patients with advanced cancers. The study found that treating asymptomatic lesions with radiation reduced skeletal-related events and extended overall survival compared to those who received no radiation.
Scientists have discovered a way to control Panama disease in bananas using specialized anti-fungal chemistries, providing hope for the global banana supply. The study's findings reveal that these chemistries can suppress the disease and maintain plant health, opening new avenues for efficient control strategies.
Scientists used a noninvasive tool of chewed plants to monitor mountain gorillas for human herpesviruses, finding no evidence of infection among the free-ranging gorillas. This study demonstrates the effectiveness of personalized health care for endangered mountain gorillas using this relatively new technique.
USC Norris Comprehensive Cancer Center is partnering with the Chinatown Service Center to address disparities in cervical cancer screening and treatment. The partnership aims to optimize access, shorten diagnosis-to-treatment timeframes, and enhance quality of care for Chinese and Latina women in Los Angeles.
A Rutgers University study has revealed that spice containers are a common source of cross-contamination in kitchens, with nearly half of samples showing evidence of contamination. The study's findings highlight the importance of proper handwashing and sanitizing of kitchen surfaces to prevent the spread of foodborne illnesses.