Articles tagged with Disease Control
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Researchers have discovered that zinc ions tune the ability of human serum albumin to prevent α-synuclein aggregation, a process linked to Parkinson's disease. Zinc binding alters HSA's chaperone function, blunting fibril formation and slowing down protein deposition that can lead to neurodegeneration.
A new platform has been created using 214,000 microbiome samples to track antibiotic-resistant bacteria globally. The data can be used to tailor guidelines on combating resistance in different regions.
Scientists at the University of Bath have discovered a novel polyamine that destroys MRSA superbug Staphylococcus aureus by disrupting its cell membrane, rendering it susceptible to antibiotics. The compound is also effective against biofilm and has shown promise as a potential new treatment option for antibiotic-resistant infections.
Researchers at Rice University have received National Science Foundation support to speed up the analysis of wastewater for coronaviruses from hours to seconds. The team will develop bioelectric sensors that deliver immediate notice about the presence of viruses like SARS-CoV-2.
The Independent Task Force Report emphasizes the need for a One Health approach to prevent or respond adequately to the next pandemic. Key findings highlight the importance of 'Smart Surveillance' to identify high-threat pathogens and invest in R&D for innovative diagnostics, antiviral strategies, and therapeutic research.
The article highlights the need for a unified approach to prevent and respond to pandemics by adopting a One Health strategy. This involves targeted preparedness, drug and vaccine research, and worldwide cooperation on surveillance and stopping disease spread.
The American College of Physicians recommends increasing funding for health services and prioritizing health promotion in Indigenous communities. Community-driven public policy is also necessary to address historical trauma, social determinants of health, and inadequate access to healthcare services.
A WVU biomedical engineer is working on a rapid diagnostic tool that can detect tick-borne infections such as Lyme disease via a blood sample on a single chip. The tool uses dielectrophoresis and machine-learning to detect diseases within one to two weeks after onset, reducing the risk of hospitalization and chronic conditions.
Researchers found that individuals with high allostatic load, a measure of chronic stress, were 2.4 times more likely to die from cancer than those with low loads. Adjusting for age, sex, and race, the risk increased to 28% for those with high allostatic load.
Researchers found that elderly Japanese individuals show a low immune response to the third mRNA COVID-19 booster vaccine. The study revealed that nearly 10% of participants had negligible antibody production despite receiving an additional dose. The findings suggest that elderly people may require specialized serological testing proto...
Rescue Biomedical's technology detects opioid overdoses and delivers naloxone to reverse them. The NIH grant will help the company complete milestones, including regulatory approval and scaling up manufacturing.
A new study found that younger women hospitalized with heart attacks had a significantly higher prevalence of cardiac risk factors and comorbidities compared to younger men. This led to higher rehospitalization rates and all-cause readmission rates, emphasizing the need for ongoing efforts to improve prevention strategies.
Global liver cancer cases are estimated to rise by more than 55% by 2040 unless preventive measures are strengthened. Countries must achieve at least a 3% annual decrease in liver cancer incidence and mortality rates to avoid this increase, according to a new report.
The study found a significant need for stable and durable diagnostics to differentiate infected animals from vaccinated ones. The researchers propose five priorities: vaccinology, antimicrobial resistance, climate mitigation, digital health, and epidemic preparedness.
A nationwide U.S. study found that mRNA booster immunizations extend COVID-19 protection for four to five months, but immunity begins to wane after this period. The study recommends additional booster doses to maintain high immunity levels against severe COVID.
A cross-sectional study of over 70,000 Asian Americans found significant variation in obesity prevalence among subgroups, with Filipino Americans having the highest rate at 28.7% and Chinese Americans the lowest at 13.2%. The study highlights the need for tailored strategies to address obesity disparities among Asian American populations.
A Rutgers-led study statistically evaluated government data to determine if COVID-19 vaccination increases the incidence of Guillain-Barré syndrome. The results show no significant association between any COVID-19 vaccinations and the disease.
Cleveland researchers reveal a new strategy to prevent blood clots by targeting overactive neutrophils, reducing clotting risk while minimizing bleeding risk. The findings may be especially impactful for cancer patients who experience blood clot complications.
A Johns Hopkins Medicine study found that COVID-19 booster shots are essential for maintaining long-term immunity against infection, particularly among older adults. The results support the CDC vaccination guidelines recommending COVID-19 boosters and highlight the importance of continued research on factors affecting immunity.
Researchers identified a specific gut bacterium responsible for antibiotic-induced GVHD after stem cell transplants. A sugar supplement was found to improve gut health by distracting the bacteria from attacking mucin in the intestinal lining, reducing complications such as GVHD.
Researchers at the University of Arizona have identified a protein called Ait1 that regulates cell growth in yeasts. This discovery presents new targets for developing antifungal drugs that can attack disease-causing yeasts while sparing human immune cells.
Researchers developed a highly effective and safe Zika vaccine technology that prevents systemic infection in pregnant mice and stimulates an immunogenic reaction. The vaccine was tested in various mouse models, proving safe and protective against the virus.
A new study led by Erika Pearce at Johns Hopkins Medicine found that the shape and function of mitochondria in Th17 cells play a crucial role in controlling their autoimmune activity. The researchers identified several molecules, including LKB1, that can influence this process, paving the way for potential therapeutic modifications.
A new method, EPISENS-S, has been developed to measure SARS-CoV-2 in wastewater with high sensitivity. This allows for the estimation of COVID-19 prevalence, including asymptomatic cases. The method was found to be approximately 100 times more sensitive than existing methods.
Researchers have isolated a new fungus, Beauveria caledonica, that can be used for biological control of banana borers and Fusarium wilt, two major threats to tropical and subtropical crops. The fungus produces a secondary compound called oosporein, which intensifies its action against the disease.
The use of voice control smart devices in children may impede critical thinking, empathy, and compassion. Devices can't teach children how to behave politely and lack non-verbal communication skills.
The USPSTF recommends screening for syphilis in asymptomatic, nonpregnant individuals who have ever been sexually active. Syphilis cases increased from a record low in 2000 to 11.9 cases per 100,000 population in 2019.
The TTUHSC team will provide no-cost colorectal cancer screening and colonoscopies to underinsured and uninsured people living in South Plains region counties. The FIT-STOP program aims to find signs of early-stage colorectal cancer to prevent treatment needs, leveraging existing relationships with partners.
Researchers are studying the interaction between obesity and nitric oxide synthase in triple-negative breast cancer, aiming to develop a new treatment strategy. Another team is investigating the role of NHE6 protein in multiple myeloma resistance to daratumumab treatment, with the goal of improving therapy outcomes for patients.
A cohort study of nearly 200,000 people found that intentional weight loss reduces the risk of type 2 diabetes for those who are overweight or obese. However, for lean individuals, weight loss attempts are associated with longer-term weight gain and higher risks of type 2 diabetes.
Mathematical models suggest that only 1 in 5 COVID-19 cases were counted worldwide, resulting in an estimated 600 million to 2.4 billion actual cases globally. The wide range of estimated cases highlights the problems with accuracy of reported numbers due to data tampering, inconsistent reporting, and lack of uniformity.
The University of Exeter team identified a 'master regulator' that controls the formation of invasive hyphae in the fungus Zymoseptoria tritici. This discovery provides a crucial target for developing new control strategies against Septoria tritici blotch, a destructive fungal disease affecting wheat yields worldwide.
Researchers found that symbiotic fungi in reared ambrosia beetles differed from those in wild beetles, potentially leading to a new biocontrol method for preventing wilt disease. The study identified nine filamentous fungi and one yeast as symbionts, including previously undescribed species.
A study found that the 2021/22 influenza vaccine had only 36% effectiveness against A(H3N2) in Canada, with a mismatch between the vaccine strain and the circulating virus. This suggests that the replacement of the vaccine strain for the upcoming season is necessary.
Researchers at Georgia State University have discovered a way to prevent and treat gonorrhea by generating a mutation in a key molecule. The study found that inhibiting the bacterial pathogen's ability to hijack human immunity proteins could block gonorrhea infection.
A new study found that only around half of older adults with hypertension regularly check their blood pressure at home. Those who received a healthcare provider's recommendation to do so were three and a half times more likely to monitor their blood pressure regularly.
Researchers developed a faster, more affordable method to analyze serological data and predict COVID-19 wave behavior. The study showed that vaccination boosted immunity, with hybrid immunity producing higher protection levels. Antibody levels rose quickly after the first dose, especially in cities where case numbers were highest.
Research from UVA Cancer Center finds that an unhealthy gut microbiome can trigger changes in normal breast tissue, facilitating cancer's spread to other parts of the body. The study suggests that targeting the gut-mast cell relationship could help prevent breast cancer recurrence and metastasis.
A literature review suggests a significant increase in monkeypox cases globally, with human-to-human transmission now the primary mode of transmission. The study highlights the need for improved surveillance and investigation into potential risk factors and treatments.
A study at the University of Helsinki found that periodontitis has a particular link with diabetes and accelerates its progression. The research highlights the importance of considering general and oral health as a whole in healthcare to achieve better treatment outcomes.
A new study from the University of Maryland cautions that delayed interventions make it harder to eliminate monkeypox. The research suggests that stronger and better-adapted variants may evolve if case numbers are low, making it challenging to control outbreaks.
Women with a history of gestational diabetes are at substantially higher risk of cardiovascular and cerebrovascular diseases, including coronary artery disease, heart attack, and stroke. Continuous monitoring is crucial to mitigate these risks.
Researchers engineered mosquitoes to produce compounds that stunt malaria parasite growth, reducing the risk of disease transmission. The technique could be combined with gene drive technology to drastically cut malaria transmission in real-world settings.
Numerous gaps between dietary intake and recommended guidelines are found, particularly among vulnerable families, with race and ethnicity disparities persisting. A unified plan can improve nutritional outcomes by strengthening federal policies and programs.
A systematic review of children and teens with type 1 diabetes found that girls have poorer metabolic control, are more likely to be hospitalized with serious complications, and require higher insulin doses. The study highlights the need for targeted efforts to improve awareness and care for young females with type 1 diabetes.
Tel Aviv University researchers discovered that skin cancer cells interact with astrocytes in the brain, promoting metastasis. By inhibiting this interaction using existing treatments, they delayed the spread of melanoma to the brain by 60-80%. This breakthrough has implications for treating advanced-stage melanoma.
Cancer cells become resistant to chemotherapies by slowing down DNA replication forks, allowing them to avoid collisions with chemotherapy drugs. A kinase called DNA-PKcs acts as a sensor when a fork is stressed and promotes slowing of the fork and chemo-resistance.
A new study by the University of Maryland found that white-tailed deer in suburban environments often bed down and spend the night within 50 meters of residential properties. This revelation has significant implications for tick management and reducing the risk of human exposure to diseases like Lyme disease and anaplasmosis.
A new study published in PLOS Medicine found that people with hospital-treated infections in early- and mid-life had a higher risk of developing Alzheimer's disease (AD) and Parkinson's disease (PD). The research analyzed data on over 291,000 cases and matched controls to identify the association between infections and neurodegenerativ...
A new study published in the Journal of the American Heart Association found that individuals with autoimmune diseases are at a higher risk of complications after a heart attack. The research emphasizes the importance of controlling cardiovascular disease risk factors and developing personalized treatment plans for this population.
The Society for Healthcare Epidemiology of America highlights the need to strengthen antibiotic stewardship programs to address overuse of antibiotics in early stages of viral epidemics. The guidance provides strategies for hospitals and healthcare personnel to improve antibiotic prescribing and diagnostic testing.
A cercarial dermatitis outbreak occurred in Chana district, South Thailand, affecting rice farmers, due to ruminant parasites like Schistosoma indicum. The study identified two snail species as intermediate hosts for flatworms causing the disease.
A recent study published in Ear, Nose & Throat Journal found that twice-daily nasal irrigation with saline solution significantly reduced hospitalizations and deaths among patients with COVID-19, particularly those aged 55 and older. The technique is safe, effective, and inexpensive, offering a vital public health impact.
A study in the Netherlands found that restricting flights from countries where COVID-19 variants of concern emerge is not enough to halt their spread. The researchers analyzed nearly 40,000 genome sequences and found that all four VOCs had already been introduced into the country by the time flight restrictions were implemented.
The US Preventive Services Task Force (USPSTF) states that screening for type 2 diabetes in asymptomatic children and adolescents under 18 has insufficient evidence to support a recommendation. As of 2018, approximately 23,000 children and adolescents had type 2 diabetes, with incidence rates rising.
A review article suggests that retinol-binding protein-4 (RBP4) may be a potential target for clinical intervention in non-alcoholic fatty liver disease. The study highlights the importance of RBP4 in the pathogenesis of NAFLD, including its role in inducing hepatic de novo lipogenesis and impairing fatty acid oxidation.
A study led by Arizona State University Professor Gabriel Shaibi found that a community-based program combining education and exercise significantly improves the health of Latino children at risk for diabetes. The program, which included 117 families from around the Valley, provided culturally focused lessons on healthy eating and phys...
Researchers from Johns Hopkins Medicine and Dana Farber Cancer Institute found that irisin reduces levels of a protein linked to Parkinson's disease and halts movement problems in mice. Irisin also speeds up the transport and degradation of alpha synuclein via fluid-filled sacs called lysosomes in brain cells.
The University of California, Davis has received a $10 million grant to continue its work on managing and preventing mosquito- and tick-borne diseases. Researchers will focus on finding effective methods to stop these diseases while training the next generation of public-health scientists.
A study published in JAMA Internal Medicine found that COVID-19-associated hospitalizations among unvaccinated adults were significantly higher than those with booster doses. The study suggests continued vaccination efforts for eligible persons to mitigate hospitalization rates.