Articles tagged with Disease Control
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Researchers at UCLA Health have found that masks can prevent not only COVID-19 but also whooping cough, while obesity is linked to an increased risk of stroke and cognitive impairment. The institute has also designed a clinical trial to reduce the use of low-value treatments for Alzheimer's disease.
A study analyzed the potential of a bacterium to combat coffee rust, a major challenge for Brazilian coffee growers. The researchers found that the bacterium produces antibacterial and antifungal compounds, as well as proteins associated with protection against water stress, making it a promising candidate for biological control.
Researchers developed a method to estimate seroprevalence using blood donation samples, offering insights into the first year of the COVID-19 epidemic in Brazil. The study found significant differences among regions and subgroups, highlighting the need for real-time tracking and forecasting of future waves.
A multi-state study found that bivalent booster vaccines significantly reduce COVID-19-related emergency department or urgent care visits and hospitalization rates. The study showed a 57% reduction in COVID-19 related emergency department or urgent care visits compared to unvaccinated adults.
A new study published in The Journal of Rural Health found that urban men who have sex with men (MSM) are more likely to get vaccinated and tested for Mpox than their rural counterparts. The study also revealed that rural MSM perceived themselves as less susceptible to the disease and had lower intention to be vaccinated.
Researchers at Kyoto University have discovered a vital role of two proteins, ABCA1 and Aster-A, in maintaining the asymmetric distribution of cholesterol within cells. This process allows for selective control over substances entering and leaving cells.
A global registry for gene-drive modified organisms could facilitate transparent communication, monitor ecological impacts, and inform local decision-making. Experts agree that a registry is necessary for the fair development, testing, and use of gene-drive technologies.
A study by Kaiser Permanente found that physically active individuals had a lower risk of severe COVID-19 outcomes. The research showed an association between physical activity and improved COVID-19 outcomes across major demographic groups, including black, Hispanic, and Asian patients.
A large VA clinical trial found that chlorthalidone (CTD) was not superior to hydrochlorothiazide (HCTZ) for preventing cardiovascular disease or non-cancer death. The study enrolled over 13,500 Veterans with high blood pressure and showed no difference between the two drugs in terms of effectiveness.
The Tokyo 2020 Paralympic Games reported a lower overall injury rate of 8% compared to previous Games, but injuries sustained were more severe. Newly introduced sports of taekwondo and badminton had high injury rates, prompting calls for prevention measures.
A study of 390 participants found that involvement in patient-facing dental activities did not increase the risk of COVID-19 infection when controlled measures were in place. The study suggests that intensive control measures can mitigate the risk of SARS-CoV-2 transmission in dental clinical settings.
A randomized controlled trial found that a low-carbohydrate, high-fat diet helped patients with type 2 diabetes achieve better weight loss and glucose control over a 6-month intervention compared to a high-carb, low-fat diet. However, changes were not sustained 3 months after the intervention.
MIT researchers have identified molecules found in mucus that can block cholera infection by interfering with the genes that cause the microbe to switch into a harmful state. The protective molecules, known as glycans, prevent Vibrio cholerae from producing the toxin that usually leads to severe diarrhea.
A new study published in JAMA Network Open found that patients with depression are less likely to adhere to essential medical therapies following percutaneous coronary intervention (PCI). The study examined over 124,000 patients who underwent PCI and were diagnosed with depression, revealing a significant proportion of individuals with...
A pilot study conducted at Brigham and Women's Hospital found that a low-cost computer vision system was feasible and well-received by employees. The system accurately detected mask adherence 100% of the time, with most participants experiencing a positive interaction.
A survey study found adolescents who received routine childhood vaccines were more likely to receive a COVID-19 vaccine dose. This may indicate that addressing hesitancy about routine vaccinations can reduce concerns about COVID-19 vaccines.
Dr. Keith Chan joins Houston Methodist to enhance chemoimmunotherapy responses in bladder cancer, while also expanding research into pancreatic and skin cancers. He will lead translational research and mentor next-generation cancer researchers.
Researchers identified two molecularly distinct subsets of long COVID symptoms with opposing gene expression patterns during acute COVID-19. These findings suggest multiple independent processes leading to different long COVID symptoms, which are already present during the acute infection.
A study found that antibodies to common antibiotic gentamicin are associated with an increased risk of progression to type 1 diabetes in children already genetically at risk. The researchers also identified an association between the FUT2 gene and the production of these antibodies, which may be compounding risks for type 1 diabetes.
A recent study has unveiled how nucleotide excision repair (NER) is controlled at the molecular level, shedding light on its role in cancer treatment. The research revealed that TFIIH uses XPG to stimulate motor activity and locate damaged DNA, licensing XPG nuclease activity to excise it.
Insulin pump use has grown over two decades but disparities persist among racial, ethnic, and socioeconomic groups. Youth from lower-income backgrounds and minority groups are less likely to use insulin pumps.
Researchers found that a vaccine against the toxin produced by E. coli protects infant mice from intestinal damage, suggesting it could boost global efforts to combat childhood malnutrition. Vaccinating kids against E. coli diarrhea may prevent long-term effects like stunting and micronutrient deficiencies.
Researchers discovered that RNA interference, a viral defence mechanism, also prevents overproduction of body's own proteins in intestinal cells, promoting ER quality control. This interplay is crucial for maintaining protein balance and overall intestinal health.
Administration of vaccine boosters to nursing home residents significantly reduces SARS-CoV-2 infections and hospitalizations. The study suggests that booster vaccination may play a crucial role in preventing COVID-19-related morbidity and mortality among vulnerable populations.
A national study confirms that vaccination significantly reduces disease severity and hospitalization risk for COVID-19, even among individuals who develop breakthrough cases. Hospital stays are shorter, ICU admissions are less common, and hospital deaths are lower among vaccinated adults compared to unvaccinated individuals.
A large international study found that adopting and maintaining a healthy lifestyle may prevent up to 60% of Crohn's disease and ulcerative colitis cases. The study analyzed data from over 300,000 participants and estimated that a low risk score for inflammatory bowel disease could have prevented a significant proportion of cases if an...
A self-service vending machine filled with harm reduction supplies such as naloxone helped prevent overdoses and contributed to a decrease in Hamilton County's overdose deaths in 2021. Nearly 900 people used the machine since its installation, with nearly 16% of users reporting they had never used harm reduction services before.
A large study found that most Canadian children and adults younger than 60 had been exposed to SARS-CoV-2 through a combination of vaccination and infection. The study, conducted in British Columbia, shows a dramatic change in the proportion of the population with antibodies over the first 2.5 years of the pandemic.
Researchers investigated neuronal response to excessive iron accumulation associated with age-related neurodegenerative diseases. They identified two genes, CLU and HERPUD1, that responded to aging-related iron accumulation, highlighting potential preventative strategies.
A recent study found that consuming the most vegetables, including leafy greens and cruciferous veggies, was associated with a lower risk of developing Type 2 diabetes. Meanwhile, potatoes may not have the same benefits but aren't bad if prepared in a healthy way.
Researchers have developed a polymeric carrier for mRNA vaccines that reduces inflammation and maintains efficiency, potentially offering better cancer treatment options. The new carrier, tested in preclinical studies, shows promise for low-side-effect cancer therapy.
Research suggests that long COVID patients share similar lingering negative effects on physical, mental, and social well-being with individuals who have other illnesses. The study found moderate-to-severe residual symptoms in 40% of COVID-positive participants and 54% of those who tested negative.
A study conducted in Brazil reveals that only 75.8% of under-fifteen children in São Paulo have antibodies against measles, falling short of the ideal 94% target to prevent outbreaks. The finding is a warning sign that Brazilian children are not achieving herd immunity, making them susceptible to infection.
Researchers have identified optimal blood tests to detect Alzheimer's disease at its earliest stages. The study found that phospho-tau217 is a reliable marker for monitoring disease progression and selecting individuals for novel trials.
A study published in PLOS Medicine suggests that primary vaccination provides moderate protection against Omicron infection regardless of prior infection history. However, the additional benefit of an original booster dose is unclear in people who have previously experienced COVID-19 infection.
A recent study published in Geriatrics found that age, education, social network, pain, and depression are significant predictors of physical activity in older adults. The findings suggest that modifying these factors through targeted interventions can increase physical activity levels.
A global Phase 2/3 clinical trial found that vaccination with SCB-2019 reduced the risk of transmitting SARS-CoV-2 infection to household members. The study showed a significant reduction in symptomatic cases among vaccinated household contacts and indicated that vaccines can play an important role in controlling future outbreaks.
A large study from Argentina found that COVID-19 vaccines remain effective in preventing death in children and adolescents, regardless of the predominant circulating variant. The study's results show that vaccinated children had a 67% reduced risk of death related to COVID-19 infection during the omicron period.
A new study published in the American Journal of Cardiology found that a healthy diet can reduce the risk of cardiovascular disease by up to 10%. The Dietary Approaches to Stop Hypertension (DASH) diet, which emphasizes whole grains, lean proteins, and fruits and vegetables, showed additional benefits for women and black adults compare...
Scientists at Medical College of Georgia discover a new target to intervene in coronary artery disease, the most common type of heart disease. The target is ATIC, a gene essential for purine production, which increases in response to arterial disease.
Researchers found a reduction of 359,790 hospitalisations, but an increase of 1,873 deaths from cardiovascular diseases due to the COVID-19 pandemic. This suggests that some people may be reluctant to seek medical care even when severely ill.
A modelling study allocates vaccines to cities with higher epidemic potential and more initial cases. This maximizes the impact of a limited supply. The study emphasizes global vaccine equity and a population-level perspective in responding to outbreaks.
A study of over 1,000 healthcare workers found that medical masks may be as effective as N95 respirators in preventing COVID-19 infection. However, the results varied across countries and were influenced by factors such as vaccine use and variant circulating during the pandemic.
A recent study found that the proportion of COVID-19 deaths among young people increased in 2021 compared to 2020, resulting in a 7.4% rise in Years of Life Lost due to the virus. The median age of COVID-19 deaths decreased from 78 years in 2020 to 69 years in 2021.
Research found that male rats exposed to ifosfamide during adolescence had offspring and grand-offspring with increased incidence of diseases, including kidney and testis problems. The study's epigenetic analysis revealed changes passed down through sperm and ova, indicating a potential risk for future generations.
A research team at the University of California, Riverside has discovered the structure of a human monoclonal antibody that protects against Crimean Congo Hemorrhagic Fever virus. The study provides insights into fighting a broad range of viral strains and could lead to targeted therapeutics for infected patients.
Researchers developed a multivalent mRNA-based vaccine protecting against all 20 known influenza subtypes, providing broad protection in animal models and paving the way for clinical trials.
Biovac has concluded a licensing agreement with the International Vaccine Institute (IVI) to manufacture an oral cholera vaccine, addressing the critical shortage of vaccines needed to prevent cholera globally. The partnership aims to increase production volumes, reduce supply gaps, and support Africa's indigenous vaccine industry.
A mass testing pilot in Liverpool found a 25% reduction in COVID-19 related hospital admissions, preventing 6,829 infections and 239 hospital admissions. The study suggests large-scale voluntary community testing can reduce virus transmission and prevent hospital admissions.
Researchers found that individuals with persistent asthma have higher levels of inflammation and artery plaque, which may increase heart attack or stroke risk. The study also highlights the importance of addressing risk factors for cardiovascular disease in people with persistent asthma.
A new model examines the interplay between epidemic spreading and information diffusion to understand how reliable info can be better disseminated during epidemics. Effective prevention practices and mass media can increase the epidemic threshold, making it harder for infections to spread.
A large-scale international study found that patients diagnosed with lung cancer at an early stage via CT screening have a 20-year survival rate of 80 percent. This is compared to the average five-year survival rate for all lung cancer patients, which is 18.6 percent.
Researchers identified four partially hidden binding pockets on the SARS-CoV-2 virus's Nsp1 protein that could be targeted with drugs. These pockets are found to halt virus replication and prevent immune system shut-down, providing a promising lead for future coronavirus treatments.
Researchers discovered antibiotic-resistant bacteria can travel from the gut to the lungs in a patient, highlighting the importance of preventing pathogenic bacteria from translocating to vital organs. The study's findings suggest eliminating resistant bacteria from the gut microbiome could help prevent serious infections.
The American College of Physicians recommends policies to improve healthcare access and quality for incarcerated patients, including adequate funding and timely access to necessary services. The organization also supports treating substance use disorders as an alternative to incarceration.
A recent study found that MRI-guided adaptive radiation therapy, also known as SMART, has shown promising safety and patient outcomes data for treating locally advanced and borderline resectable pancreatic cancer. The study, led by Henry Ford Health, reported no incidence of acute grade 3 or higher gastrointestinal toxicity, with preli...
A new study from Mount Sinai Hospital finds a strong association between age-related macular degeneration and severe forms of heart disease, including heart failure, heart attacks, and stroke. The study highlights the importance of increased screening for eye disorders to diagnose undetected heart disease.
A 30-year follow-up study of patients with early breast cancer found that radiotherapy does not improve overall survival rates after 10 years but reduces the risk of recurrence in the same breast. The study's findings challenge traditional concepts of long-term anti-cancer benefits of radiotherapy.
A study of 3,110 US counties found that residential segregation is associated with increased cancer mortality. The findings highlight opportunities for targeted cancer prevention and control efforts at the county level.
The number of Candida auris cases in the EU/EEA nearly doubled between 2020 and 2021, with 11% of cases having no available information on carriage or infection. Early detection is crucial to prevent the spread of this healthcare-associated pathogen.