Articles tagged with Osteoarthritis
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The Osteoarthritis Initiative will recruit 5,000 participants aged 50+ at high risk for knee osteoarthritis. The project aims to establish a natural history database for osteoarthritis, allowing researchers to identify potential new disease targets and develop tools for understanding disease progression.
A recent study has identified eight chromosomal sites that may harbor genes for hand OA, with the strongest evidence found on chromosomes 7p and 11q. The research used a genome scan of Framingham participants and their offspring to investigate genetic linkages.
Researchers have developed a new x-ray technique called diffraction enhanced imaging (DEI) that can image cartilage and detect early stages of osteoarthritis. This technology has the potential to improve diagnosis and treatment of the disease, which affects over half of the nation's elderly.
Researchers found that a specific mutation in collagen II affects the interaction with another collagen, leading to cartilage damage and osteoarthritis progression. The study's results provide insight into how mutations in collagen genes contribute to the disease.
A new UNC research project aims to investigate the connection between osteoarthritis, emotional responses, and coping strategies. The two-year study will analyze data from over 20,000 participants to identify predictors and consequences of emotional distress in people with arthritis.
Dr. Waddell presents two studies showing viscosupplementation is safe and effective for patients with advanced osteoarthritis, delaying total knee replacements by up to 1 year.
A 250-participant study found that exercise programs reduced the risk of disability in older adults with knee osteoarthritis. The results suggest that physical exercise can play a crucial role in maintaining independence and reducing disabilities as people age.
A small study found leech therapy to be effective in reducing pain from osteoarthritis, with rapid relief seen after three days and sustained effects four weeks later. The treatment produced no side effects or infections.
A public-private partnership has been launched to combat osteoarthritis, a chronic disease affecting millions of Americans. The Osteoarthritis Initiative will provide critical funding and resources for clinical research centers to establish natural history databases and biospecimen repositories.
A new study finds that black men are 33% more likely to develop hip osteoarthritis than white men, while black women are twice as likely to develop the condition. Weight disparities account for comparable differences in women.
Researchers discovered that COMP significantly increases in the blood of people with hip or knee osteoarthritis even before X-rays reveal joint damage. Elevated levels of COMP correspond strongly with reports of joint pain and may indicate an early stage of osteoarthritis.
A comprehensive program involving exercise, weight loss, and joint protection principles is necessary for effective osteoarthritis management. Over-the-counter acetaminophen may be the only required medication for mild-to-moderate pain relief.
This issue of Annals of Internal Medicine offers guidance on identifying and treating depression in terminally ill patients. A new program combining physical therapy and exercise is shown to effectively manage osteoarthritis symptoms, potentially delaying surgery for affected adults. Meanwhile, a pet parrot infection has been transmitt...
Researchers are conducting the largest study ever to identify the genetic susceptibility for osteoarthritis, a condition affecting over 21 million Americans. The three-year study will analyze DNA samples and health histories of 1,400 families with multiple siblings diagnosed with primary generalized osteoarthritis.
The University of California, San Francisco is part of a national study evaluating medications that duplicate glucosamine and chondroitin sulfate for treating knee osteoarthritis. The four-year trial aims to assess efficacy, safety, and side effects in over 1,000 patients.
A new study suggests that gamma tocopherol in vitamin E may contribute to the development of knee osteoarthritis. In contrast, higher levels of alpha tocopherol, a common ingredient in vitamin E supplements, may help prevent the condition, particularly in African Americans.
Researchers found a strong association between leg length discrepancies of two centimeters or more and an increased risk of knee arthritis by up to 70 percent. Simple adjustments, such as special shoes or exercises, could help prevent or slow progression of osteoarthritis in millions of people.
A University of North Carolina at Chapel Hill study suggests that consuming vitamin E and other antioxidants may help reduce the risk of knee arthritis. Middle-aged and older individuals who follow a diet rich in these compounds, such as green vegetables and tomatoes, may experience a 30% lower risk of developing osteoarthritis.
A recent clinical study found that people with knee osteoarthritis who exercise in moderation experience reduced pain, improved physical performance, and less disability. The Fitness Arthritis and Seniors Trial (FAST) results compared improvement measurements in aerobic and resistance training programs to a health education program.
A new study finds that obese Blacks are more likely to experience physical disabilities due to their weight, with a 30% greater risk than Whites. Researchers at the University of North Carolina at Chapel Hill examined functional differences between Blacks and Whites in rural Johnston County.