Articles tagged with Pediatrics
A comprehensive national registry for pediatric chronic kidney disease (CKD) is essential to improve lifespan and quality of life. The study emphasizes the importance of identifying children at risk, with high mortality rates among those requiring renal replacement therapy.
A new definition of PARDS, issued by the Pediatric Acute Lung Injury Consensus Conference, has been validated through an international study. The study found that two-thirds of children with mild and moderate PARDS would not have been accurately diagnosed using adult definitions.
A new study published in Pediatric Research found that children with asthma growing up in polluted NYC neighborhoods need emergency medical treatment more often. The study suggests that these areas may have other environmental factors affecting urgent asthma treatment.
Whole genome sequencing and exome sequencing identified clinically relevant variants in 79% of patients, guiding diagnosis, risk assessment, or drug targets. The study's comprehensive approach enables rapid analysis within 40 days, making it a promising tool for pediatric cancer treatment.
A study highlights strategies to help teens with type 1 diabetes manage high cholesterol and blood pressure, including offering realistic guidance, encouraging regular exercise, and promoting healthy eating habits. The research emphasizes the importance of personalized approach and team effort in addressing these conditions.
The FDA awarded $5 million to the National Capital Consortium for Pediatric Device Innovation, co-led by Children's National Hospital and the University of Maryland. The consortium aims to develop medical devices designed specifically for children's unique needs, with a focus on asthma, heart disease, and neonatal health.
Researchers have devised a novel method to block abnormal biological signals driving the rare and fatal disease Fanconi anemia. Inhibiting a regulatory protein called Sh2b3/Lnk restored bone marrow cell function and improved genome integrity in animal studies, providing hope for better treatments for children with the disease.
A team of researchers has created an automated program to screen for malnutrition in hospitalized children, using existing patient data in electronic health records. The study found a high prevalence of malnutrition among pediatric oncology patients, with 42% overall and varying levels of severity.
A new clinical practice guideline emphasizes the importance of early identification and referral to physical therapy for infants with CMT. Early intervention can result in excellent outcomes, including full passive neck rotation and zero surgical interventions.
A recent study published in JAMA Pediatrics found that the home environment plays a crucial role in determining whether children with a genetic predisposition to obesity become overweight or obese. The study's main finding was that genetic influences on BMI depend on home environment.
The American Society for Parenteral and Enteral Nutrition (A.S.P.E.N.) has released new best practices for verifying the correct placement of nasogastric tubes in pediatric patients. These guidelines aim to improve patient safety by standardizing education, tube verification methods, and radiographic evaluation.
The Endocrine Society's Clinical Practice Guideline provides recommendations for promptly diagnosing and treating CAH throughout a patient's life. It emphasizes shared decision-making among patients, families, and healthcare professionals for the management of the disorder.
A study of 477 pediatric patients found that survival rates were not associated with the time to first defibrillation attempt. Most pediatric patients had a quick response to CPR, but the delayed response did not impact outcomes in this age group.
A Loyola Medicine study shows that an educational curriculum for physicians improves their emotional intelligence, stress management, and overall wellness. The study suggests that teaching emotional intelligence skills may improve stress management, promote wellness, and prevent burnout in resident physicians.
Researchers identified a neuronal BRAF somatic mutation causing intrinsic epileptogenicity in pediatric brain tumors, leading to a potential new therapeutic target. The mutation arose from neural stem cells and was found to alleviate seizures in animal models treated with the BRAF inhibitor Vemurafenib.
The partnership aims to develop and conduct collaborative clinical research studies on young children with various immune system disorders. The collaboration provides joint training opportunities for physician-scientists and offers comprehensive pediatric clinical support.
Children awaiting livers from deceased donors face significant disadvantages due to the scoring system, which significantly underestimates their risk of death compared to adults. The Pediatric End-stage Liver Disease (PELD) score is incompatible with the Model for End-stage Liver Disease (MELD) score used for adults.
A US children's hospital implemented a first-of-its-kind project to eliminate or reduce pain from elective needle procedures, improving patient satisfaction and staff concerns. The 'Children's Comfort Promise' project introduced four research-proven strategies, which saved time and reduced staff turnover.
The new guidelines standardize a framework for recognizing, treating and managing a child's recovery from mild traumatic brain injury. Key recommendations include screening for risk factors, safe prescribing and education for children and families.
The CDC has published a comprehensive guideline for the diagnosis and management of pediatric mTBI, which covers diagnosis, prognosis, management and treatment for all causes of pediatric mTBI. The guideline includes 19 sets of recommendations for healthcare professionals to take to improve health outcomes.
The UCSF-Stanford Pediatric Device Consortium will develop new medical devices, including a pneumonia detector and appliances for infants with cleft palate. The grant enables collaboration between geniuses to stimulate innovation in the pediatric device market.
A novel technique developed by Hong Chen uses focused ultrasound to target drug delivery to the brainstem, bypassing the blood-brain barrier. This approach has shown promise in treating diffuse intrinsic pontine gliomas (DIPG), a childhood brain cancer with a five-year survival rate of less than three percent.
A new CDC treatment guideline for children with concussions provides guidance on diagnosis, management, and follow-up care. The guideline recommends validated symptom scales for diagnosis and assessing risk factors for prolonged recovery.
Research finds that experiencing homelessness for over six months can cause long-lasting harm to a child's physical and developmental health. The study also reveals that prenatal and postnatal homelessness increase the risk of negative health outcomes.
Researchers identified a gene mutation causing abnormal lymphatic circulation and restored normal vessel architecture using signal inhibitors. The study may lead to a new therapy for patients with central conducting lymphatic anomaly, a complex condition affecting immune function and fat transport.
The European Commission has approved Kymriah, a personalized CAR T-cell gene immunotherapy, for treating pediatric and young adult patients with aggressive blood cancers. The therapy has shown strong and durable response rates, providing a new hope for young cancer patients in Europe.
Researchers have developed a new subcutaneous intrathecal catheter system (SIC) to deliver nusinersen to SMA patients, significantly reducing hospital stays and costs. The SIC method allows for faster and more efficient administration of the drug, with an average hospital stay of less than 55 hours.
Researchers identified vulnerabilities to target in a high-risk pediatric tumor, rhabdomyosarcoma, through an integrated analysis of cellular origins and epigenetic changes. The study promotes precision medicine by prioritizing drug development and highlighting the importance of preclinical models in streamlining treatment strategies.
A new analysis found that antibiotic use in children leads to an estimated 69,000 emergency room visits each year for allergic reactions and other side effects. The risk varies by child age and type of antibiotic used, with younger children aged 2 or under being at highest risk.
Researchers tested two commercially available baby monitors, finding that one detected low oxygen levels inconsistently while the other falsely displayed low pulse rates. These alarming results highlight the need for regulation of these products to prevent unnecessary anxiety and medical interventions in healthy infants.
A new roadmap for improving health has been developed by UCLA researchers using software that aggregates data on how to treat conditions of children with complex medical situations. The team identified 10 key health outcome domains, including social integration and family support, to help provide a comprehensive model of care.
A new study shows that a University of Missouri program significantly reduces diagnostic wait times for young children at highest risk for autism. The ECHO Autism program provides hands-on training, virtual discussions and practice to help primary care providers diagnose autism in young children, saving families an average of 172.7 mil...
Challenges facing ID physician scientists include inadequate funding for fellowship opportunities and steep compensation disparities, leading to a decline in trainees pursuing careers as physician researchers. To address this, medical societies recommend expanded mentorship, training opportunities, and workforce diversity measures.
A study published in JAMA Network Open found that physicians who showed unburied empathy during care conferences had more effective conversations with families, leading to better patient outcomes. The researchers recommend slowing down, using the 'NURSE' mnemonic, and avoiding transitions like 'but' to improve empathetic communication.
Pediatricians in a telemedicine service face difficulties diagnosing from a distance, managing patients' expectations, and working alone. To overcome these challenges, they use intuition, experience, and protocols, highlighting the need for special skills and training.
Nationwide Children's Hospital has launched an initiative to treat a neighborhood as a patient, targeting 'neighborhood effect syndrome' with housing development and community engagement. The Healthy Neighborhoods Healthy Families program has seen measurable improvements in housing stock, youth emotional health, academic performance, a...
The Philadelphia Pediatric Medical Device Consortium has awarded seed grants to six companies developing medical devices for children, including an airway clearance system and a vision acuity test. These innovative devices aim to address unmet clinical needs in pediatric care, such as cystic fibrosis and urinary flow disorders.
The Pediatric NEXUS Head Computed Tomography Decision Instrument (DI) reliably guides blunt trauma imaging decisions and may decrease head CT imaging in low-risk pediatric populations. The study found that the decision instrument could significantly reduce head CT utilization by up to 34%.
The American Academy of Sleep Medicine has published a clinical practice guideline on the use of actigraphy in evaluating adult and pediatric patients with suspected sleep disorders. Actigraphy is recommended as a useful tool for gathering objective data on sleep habits, but not used as a substitute for polysomnography.
A new study by Vanderbilt University found that opioid treatment programs in Appalachian states have limited capacity, with only 50% accepting insurance. Pregnant women are particularly excluded, with shorter wait times only when accepted to treatment programs.
A new study found that young adults with incarcerated parents are more likely to skip healthcare, engage in risky behaviors, and develop physical and mental health conditions. The study highlights the need for targeted interventions to mitigate the effects of parental incarceration on youth behavior.
A new study from the University of California - Los Angeles Health Sciences reveals that parents who experienced severe childhood trauma are more likely to have children with behavioral health problems. The study found a strong association between parents' adverse childhood experiences and their children's behavioral health issues, par...
A study by Stanford researchers found that physician burnout is equally, if not more, responsible for medical errors as unsafe work environments. The study suggests that addressing burnout among healthcare providers is crucial to reducing medical errors and improving patient safety.
A new computational strategy using Bayesian analysis and CRISPR/Cas9 screening technology has identified 29 genetic changes contributing to rhabdomyosarcoma, a common childhood cancer. The study suggests potential treatments for the disease and provides a general approach for identifying oncogenic drivers in other cancers.
A therapist-based intervention significantly reduced dating violence perpetration and depression symptoms in teens. The study found a 47% lower rate of self-reported dating violence among participants who received the intervention compared to those without one.
A survey of 1,167 parents of children with Down syndrome found that 49% give or have given supplements to improve their child's health. The most popular supplement categories include antioxidants and vitamins, but some products pose unknown health risks due to lack of regulation.
A study by Sapienza University of Rome found that children of same-sex parents had fewer reported difficulties and normal scores in psychological adjustment compared to children of different-sex parents. Family functioning, particularly for gay fathers, was also better among same-sex parents.
Researchers found that children with multiple allergies are nine times more likely to develop eosinophilic esophagitis. The study suggests a common underlying biological cause among these allergies and implies that early treatment of one allergy may prevent later disorders.
A NIH-funded study of 91 youth ages 10-19 found that neither initial treatment with long-acting insulin followed by metformin, nor metformin alone preserved the body's ability to make insulin. Metformin did show modest improvement in blood glucose levels.
Researchers found exponential growth in pediatric Lyme disease cases from 2003 to 2013 in western Pennsylvania, shifting from rural to non-rural areas. Children with Lyme disease were more likely to be seen by primary care providers for late-stage symptoms such as arthritis.
A study of 829 adolescents found that both short sleep duration and poor sleep efficiency are associated with increased abdominal fat deposition and cardiometabolic risk. In contrast, longer sleep duration and higher efficiency were linked to reduced waist circumference, lower blood pressure, and improved HDL cholesterol levels.
A study has identified genetic variants associated with an increased risk of developing pediatric nephrotic syndrome, a debilitating kidney disease in children. The findings could lead to new diagnostics and treatments.
A new study finds that a fruit and vegetable prescription program can significantly increase shopping at farmers' markets among caregivers of children living in poverty. The program, implemented in Flint, aims to address food insecurity by providing access to fresh produce.
Researchers found that honey and sucralfate significantly reduce morbidity and mortality from highly caustic batteries. Ingesting honey before removing a button battery may protect against serious injuries in small children. The study's findings will inform clinical practice and guidelines for managing button battery ingestions.
A study published in Communications Biology has linked the protein PARP1 to an aggressive form of pediatric liver cancer called hepatoblastoma. Researchers found that inhibiting PARP1 slowed or stopped cancer progression in laboratory tests, providing a potential treatment target for this disease.
A study published in JAMA Ophthalmology found that US pediatric eye injuries decreased by 26.1% from 2006 to 2014. Most of these injuries had a low risk of causing permanent vision loss. In contrast, sports and household-related injuries increased, while motor vehicle crashes, gun-related incidents, and chemical burns declined.
Dr. Peña has made significant contributions to pediatric surgery, particularly in treating anorectal malformations and other congenital anomalies of the pelvis. His work introduced the posterior sagittal anorectoplasty (PSARP) procedure, widely adopted by top surgeons worldwide.
According to a new study published in Pediatrics, adolescents with severe obesity should not be excluded from weight loss surgery due to pre-existing psychiatric disorders. The research found no association between pre-operative psychiatric diagnosis and post-surgical weight loss outcomes, suggesting that bariatric surgery can be equal...
A free tax preparation program in pediatric clinics helped over 753 clients receive $1.6 million in federal tax returns, with a significant improvement in tax filings and client knowledge about the EITC. The program also reduced financial stress for low-income families and maximized their tax refunds.
A consensus statement from pediatric and law experts defines abusive head trauma (AHT) as a medical diagnosis, not a legal determination. Key findings include few infants with AHT having isolated injuries without retinal hemorrhages or other signs of abuse.