Articles tagged with Fatty Acids
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A randomized controlled trial found that omega-3 fatty acid supplementation had no beneficial effects on disease activity in patients with relapsing-remitting multiple sclerosis. The study included 92 patients who received either omega-3 fatty acids or a placebo for six months, followed by interferon beta treatment for another 18 months.
A study by Uppsala University researchers found that humans have a unique genetic variant allowing for efficient production of Omega-3 and Omega-6 fatty acids from vegetable oils. This adaptation is linked to the development of modern human brain capacity but increases the risk of cardiovascular disease in today's life situation.
A new study finds a protective gene in fat cells that helps regulate blood sugar and insulin levels, potentially leading to a new therapeutic strategy for preventing and treating type 2 diabetes. The discovery challenges popular notions of body fat and health.
Researchers found that a 1% concentration of fish oil in savory-flavored yogurt can provide more than the recommended daily intake of n-3 fatty acids. The studies demonstrated high acceptance and flavor preference among nutritionally motivated consumers, suggesting a potential market for such products.
Researchers found that consuming two servings of salmon per week improves omega-3 fatty acid levels in both pregnant women and their babies. This increase in omega-3s enhances the body's antioxidant defenses, potentially helping to reduce oxidative stress associated with pregnancy.
Researchers analyzed fatty acid composition and DNA analysis to identify the source of US-grown pine nuts. Most samples found to be mixtures of different species, but combining these methods didn't definitively link to 'pine mouth',
A study published in PLOS ONE found that dietary trans fatty acids are associated with irritability and aggression in both men and women of all ages. The research, which analyzed data from nearly 1,000 adults, suggests a strong link between trans fat consumption and aggressive behaviors.
A recent study published in Obesity by Rutgers University researchers found a link between genetic variation in CD36 and the ability to perceive fatty acids. Those with this variation were more sensitive to fat texture but preferred high-fat foods, highlighting a potential genetic basis for obesity development.
A study published in Neurology found that people with lower blood levels of omega-3 fatty acids had lower brain volumes equivalent to about two years of structural brain aging. Omega-3 deficiency was also linked to poorer performance on tests of visual memory and executive function.
Scientists discovered that problems controlling blood sugar in the intestines can lead to chronic inflammation and insulin resistance. Researchers found a link between fatty acid synthase enzyme defects and diabetes, suggesting potential new targets for therapy.
A study by the University of Granada found that infants born to mothers who consumed more fish during pregnancy scored higher in verbal intelligence and fine motor skill tests, and presented increased prosocial behavior. Fish oil is a primary source of long-chain Omega-3 fatty acids, which are crucial for brain development.
Researchers have identified a human receptor that can taste fat, suggesting individual variability in sensing fat's presence. People with a specific genetic variant of the CD36 gene are more sensitive to fat, making it easier to detect.
A recent study published by the Technical University of Munich found no evidence to support the theory that fish oil consumption during pregnancy prevents excessive infant adipose tissue growth. The INFAT study, which monitored 208 expectant mothers and their children for over a year, showed no difference in infant adipose tissue growt...
Researchers from the University of Granada found that oleic acid and hydroxytyrosol in virgin olive oil, and n-3 polyunsaturated fatty acids in fish, can prevent or mitigate acute pancreatitis. The Mediterranean diet has been recognized by UNESCO as Intangible Cultural Heritage.
Researchers find that toxic byproducts from unsaturated fat breakdown lead to severe inflammation, cell death, and multi-system organ failure in obese acute pancreatitis patients. The study provides new insight into how fat can induce complications after sudden inflammatory illnesses.
Researchers identified three fatty acids involved in Burmese pythons' extreme heart growth after large meals. These fatty acids may trigger healthy physiological cardiac hypertrophy in diseased human hearts.
A CU-Boulder study finds that fatty acids circulating in python bloodstreams promote healthy heart growth, with no evidence of fat deposition in the heart. The researchers also saw an increase in the activity of a key enzyme protecting the heart from damage.
A University of Bristol study found that omega-3-rich diets reduced disease by 50% compared to a standard diet in guinea pigs with naturally occurring osteoarthritis. Omega-3 influences biochemistry and helps prevent disease progression, potentially controlling established osteoarthritis.
Patients with acute lung injury receiving dietary supplements did not experience improved outcomes, but rather more days on ventilators and in the ICU. The supplements increased plasma EPA levels but had no statistically significant impact on mortality rates.
Researchers at the University of California San Diego have identified unsaturated and polyunsaturated fats from plants and cold-water fish as beneficial for health. These fats block JNK activation by saturated fatty acids, which are linked to adverse health effects.
Researchers solved the 40-year mystery of how desaturase enzymes insert double bonds in plant fatty acids. They discovered that a single amino acid, far from the enzyme's active site, can exert 'remote control' over double bond placement by binding to a carrier protein.
Research published in The Journal of Physiology identifies a link between maternal diet and child allergies, finding that polyunsaturated fatty acids improve gut immune cell response. This may reduce allergy risk by accelerating the development of a healthy immune system.
Researchers at University of California - San Diego have discovered that inhibiting a single enzyme helps slow disease progression in a mouse model of multiple sclerosis. The study suggests that targeting fatty acid metabolism could lead to new therapies with fewer side effects.
Research found that embryos exposed to high levels of saturated fatty acids have fewer cells, altered gene expression, and impaired metabolic activity. This study suggests a link between maternal obesity and diabetes and reduced fertility, highlighting the importance of pre-pregnancy health for successful conception.
Rice University researchers developed a method to rapidly convert glucose into biofuels and petrochemical substitutes by reversing the beta oxidation cycle in bacteria. They produced butanol, a biofuel, about 10 times faster than previously reported organisms, using cheap feedstocks like glucose and mineral salts.
Researchers at Thomas Jefferson University discovered that blocking a receptor of a key hormone in the renin-angiotensin system reduces cancer cell growth by activating the enzyme AMPK, which inhibits fatty acid synthase. This finding suggests a potential target for chemopreventive agents to fight pancreatic cancer.
In a new study, researchers found that when brain cells are starved, they turn to self-cannibalism through autophagy, which increases hunger signals and makes diets ineffective. Blocking this process may lead to weight loss and improved energy balance.
Dr. Shapira's research shows that eggs laid by hens with healthier feed can lessen oxidation of LDL cholesterol, potentially reducing heart disease risk. However, these 'healthier' eggs are not widely produced and may be more expensive due to specialized chicken feed.
Kezhong Zhang is studying CREBH's role in regulating NAFLD through a $1.7 million NIH grant. He aims to understand how CREBH controls fat production and digestion, with implications for preventing and treating NAFLD.
Researchers at Wayne State University are investigating the link between toxicity of fatty acids and obesity-diabetes connection. They're developing sensors to visualize fatty acid production and signaling in live cells, aiming to create new anti-obesity therapeutics.
A new study reveals that omega-3 fatty acids in fish oil can normalize behavior in mice models of bipolar disorder, reducing depressive symptoms and decreasing alcohol abuse. The researchers also found correlations between molecular changes and biomarkers, paving the way for targeted clinical studies in humans.
A research team at Arizona State University has developed a process that reprograms photosynthetic microbes to secrete high-energy fats, eliminating the need for costly additional processing steps. This breakthrough could make renewable biofuels more commercially viable.
A study found that postmenopausal women who ate more baked/broiled fish had a 30% lower risk of heart failure compared to those who rarely ate it. Darker fish, such as salmon and mackerel, were associated with a greater risk reduction than lighter fish.
A human genetic variant associated with a 30% reduced risk of developing severe malaria has been identified. The FAS locus variant can prevent excessive immune responses in infected children, reducing the severity of the disease.
A new study confirms that fish livers contain long-chain polyunsaturated fatty acids, which are beneficial to health and have been found in high levels in certain species. The researchers highlight the nutritional properties of these organs and suggest that their use could reduce environmental pollution caused by discarding fish entrails.
A nationwide study found that men with high levels of omega-3 fatty acids in their blood have a two-and-a-half times higher risk of developing aggressive prostate cancer. In contrast, those with high levels of trans-fatty acids had a 50% lower risk of high-grade prostate cancer.
Fat, oil, and grease (FOG) harden into calcium-based fatty acid salts, creating deposits that reduce wastewater flow and cause environmental problems. Researchers have discovered the molecular mechanism behind FOG deposit formation using FTIR spectroscopy.
The study identified a microRNA that may elucidate the biological mechanism behind obesity-related traits in individuals carrying the PLIN4 gene variant. Higher omega-3 fatty acid intakes were associated with lower body mass index and weight in carriers of the gene variant.
Researchers found that alpine marmots increase n-6 polyunsaturated fatty acid concentrations in their cell membranes before hibernation, preparing for low temperatures. This seasonal change is reversed upon hibernation termination and appears to be controlled by an endogenous clock.
A study from UNC School of Medicine found that saturated fatty acids activate immune cells to produce inflammatory protein interleukin-1beta, leading to insulin resistance and type 2 diabetes symptoms.
A review of vegetarianism's biochemistry suggests that vegans may be at higher risk for blood clots and atherosclerosis due to low levels of essential nutrients. Increasing dietary omega-3 fatty acids and vitamin B12 can help mitigate these risks, particularly through sources like salmon, walnuts, and fortified milk.
A large population study found that regular consumption of fish and omega-3 fatty acids was associated with a significantly reduced risk of developing age-related macular degeneration in women. The study, published in Archives of Ophthalmology, found that higher intake of DHA and EPA was linked to a 38% lower risk of the condition.
Researchers found that brain insulin suppresses lipolysis, a process breaking down triglycerides and releasing fatty acids, which worsens diabetes. Impaired brain insulin signaling can lead to a vicious cycle of inflammation and insulin resistance.
A new perspective paper challenges long-held beliefs about saturated fatty acids and cardiovascular disease, highlighting the complexity of diet's effects on CVD risk. Experts conclude that blood lipid ratios and food matrices, including nutrients like protein and calcium, play a more significant role than just fatty acid content.
Researchers used fruit flies to study fetal alcohol syndrome, finding that prenatal alcohol exposure can cause developmental problems such as intellectual disabilities and abnormal facial features. The study establishes a new model system for studying FAS, which may lead to the development of new therapies.
Research in Nature Neuroscience found that a diet low in omega-3 poly-unsaturated fatty acids alters the functioning of the endocannabinoid system, leading to changes in brain function and behavior. The study provides new insights into the link between omega-3 deficiency and depression.
A review of vegetarianism's biochemistry finds vegans at elevated risk for blood clots and atherosclerosis. Key nutrients like omega-3 fatty acids and vitamin B12 can mitigate this risk with dietary supplements or fortified foods.
Researchers found that omega-3 deficient mice exhibited disturbed synaptic functions and emotional behaviors, including depression. The study suggests that chronic malnutrition during intrauterine development may influence synaptic activity involved in emotional behavior in adulthood.
A recent study by Washington University researchers discovered that fatty acid synthase and nitric oxide synthase enzymes interact in endothelial cells to cause blood vessel damage in diabetes. By understanding this mechanism, they hope to develop new treatments for vascular complications of the disease.
Research suggests that organic milk has higher levels of nutritionally beneficial fatty acids compared to conventional milk, regardless of the time of year or weather conditions. This could help farmers adapt to changing climates by improving milk quality.
A new mouse model has been created to study how lipid sensing and metabolism in the brain relate to energy balance and body weight. The research found that mice with a deficiency of lipoprotein lipase in neurons became obese on a standard diet, leading to decreased food intake and increased sedentary behavior.
A study found that people in 'stroke belt' states, particularly African-Americans, eat more fried fish than others, contributing to a higher risk of death from stroke. The American Academy of Neurology attributes this to the loss of natural fatty acids when frying fish.
A study published in Neurology found that eating fried fish in the stroke belt states of Alabama, Georgia, and others is associated with a higher risk of stroke. The study suggests that omega-3 fatty acids in fish may reduce stroke risk, but frying destroys these nutrients.
A natural substance in dairy fat, trans-palmitoleic acid, has been identified as a potential factor in reducing the risk of type 2 diabetes. The compound is found in milk, cheese, yogurt, and butter and may mimic the normal biologic role of its produced counterpart, cis-palmitoleic acid.
Researchers at UCLA have discovered a way to strengthen polyunsaturated fatty acids, making them less susceptible to oxidation. This breakthrough could lead to the development of more effective nutritional supplements and new approaches to combatting neurodegenerative diseases like Parkinson's and Alzheimer's.
A study published in Cell Metabolism found that a protein called Angiopoietin-like protein 4 (Angptl4) protects against the severe inflammatory response caused by high levels of saturated fat. Mice deficient in this protein showed massive lymph node expansion and died after consuming a diet high in saturated fats.
Children with Fetal Alcohol Syndrome (FAS) show deficits in both delay and trace eyeblink conditioning, a finding that could aid in assessing and diagnosing FAS. Researchers tested 63 children on delay conditioning and found that 33% met the criteria compared to 79% of control group members.
Scientists have engineered plants to accumulate high levels of desired compounds that could be used to make plastics. The research uses a new metabolic pathway in plants to produce a type of fatty acid that could serve as a source for chemical building blocks.
A randomized controlled trial of DHA supplementation in individuals with mild to moderate Alzheimer's disease found no beneficial effect on cognitive and functional decline. The study included 402 participants who received either DHA or a placebo for 18 months. No significant difference was observed in the rate of brain atrophy, ADAS-c...
A study found that consuming polyunsaturated fatty acids, particularly DHA and EPA, is associated with a reduced prevalence of periodontitis. The research suggests that dietary therapy using n-3 fatty acids could be a less expensive and safer method for preventing and treating gum disease.