Articles tagged with Lipopolysaccharides
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A prospective cohort study found that increased lymphocyte counts, decreased serum LPS levels, and specific mucin expression patterns are associated with antralization. The study suggests that acid reflux is closely linked to antralization.
The study reveals that Christensenella tenuis significantly reduces LPS levels and improves glucose and lipid metabolism in diet-induced obesity mice. It achieves this through a distinct bile acids-LPS interaction, preventing LPS from translocating into the bloodstream.
Researchers at Nara Institute of Science and Technology reveal the essential role of LptM in maturing and stabilizing the LptDE complex, a key component of Gram-negative bacteria's outer membrane. This finding provides fundamental insights that may support antibiotic design and advances understanding of bacterial virulence.
A new study reveals that maternal immune activation can alter hippocampal neuron excitability in newborn rats, with implications for neurodevelopmental disorders. Prenatal inflammation has been linked to conditions like autism, schizophrenia, and depression, and may underlie their increased risk.
Researchers found that neuroinflammation in the hippocampus significantly alters motivation and behaviour in mice, particularly in females. This study suggests that treatments targeting hippocampal neuroinflammation could help reduce cognitive and behavioural symptoms in diseases such as Alzheimer's and Depression.
Researchers discuss the role of gut microbiota in regulating basal inflammation levels and promoting healing of the bowel after surgery. Weakened gut barrier function may lead to persistent low-grade inflammation and increased risk of cancer recurrence.
A recent study revealed that specific bacteria produce a carbohydrate compound that induces settlement and metamorphosis in larvae of the warm-water tubeworm Hydroides elegans. This process, known as biofouling, can coat ship hulls and propellers, causing significant economic damage.
Research finds increased neural activity in theta frequency band within the basolateral amygdala of depressed rats, correlating with behaviors like reduced exploration and anhedonia. The study's findings suggest that targeting specific brain regions could lead to more effective treatments.
Researchers found that bisphenol A (BPA) inactivates microbial lipopolysaccharides (LPS), a key trigger for allergic asthma. This disruption increases susceptibility to asthma in mice, highlighting a potential link between BPA exposure and immune disorders.
Researchers found that p21 knockout mice experienced reduced senescent cell presence, alleviated chronic lung inflammation, and improved fitness. Resident epithelial and endothelial cells played a significant role in mediating the p21-dependent inflammatory response.
Researchers found that klotho has anti-inflammatory and neuroprotective effects on cultured glial cells, reversing increased secretion of pro-inflammatory cytokines. The study supports klotho's therapeutic potential in pathological processes with a neuroinflammatory component.
Research led by Drs. Yuhai Zhao and Walter J Lukiw reports a pathway from the gut to the brain that contributes to Alzheimer's disease development. Adequate dietary fiber intake can prevent this process. The study suggests a potential means to modify the abundance of microbes in the microbiome.
Researchers found that birds infected with lipopolysaccharide from bacteria reduced their body temperature by 2°C to conserve energy. In contrast, chicks fed and warm did develop fever. The study suggests that regulated hypothermia is an energy-saving response during severe infection, prioritized over maintaining a fever.
A new study published in PNAS reveals that a specific bacterial compound, lipopolysaccharide, induces larval marine tubeworms to settle on the seafloor and undergo metamorphosis. The discovery offers hope for coral reef restoration, mariculture, and biofouling prevention.
A new study from Karolinska Institutet and Helmholtz Center Munich found that macrophages show altered inflammatory and metabolic expression several months after mild COVID-19. Even though most individuals were symptom-free, their immune systems were more sensitive than those of healthy counterparts.
A study published in Cell Reports reveals that LPS protects against developing asthma when combined with allergens containing cysteine protease enzymatic activity, but promotes development when paired with allergens lacking this enzyme. This protective effect relies on the production of GM-CSF by non-classical monocytes.
A recent study has discovered genetic markers associated with high levels of lipopolysaccharide (LPS) in the blood, a toxin linked to sepsis and cardiovascular diseases. The research also found a connection between LPS levels and blood coagulation disorders, such as thromboembolism and stroke.
A study in mice and human blood samples found that HDL3 protects the liver by blocking gut bacterial signals that cause inflammation. The researchers identified a special type of HDL called HDL3 that is produced by the intestine, which blocks lipopolysaccharide signals that activate immune cells.
Researchers found that blood coagulation factors VII, IX, and X can hydrolyze lipopolysaccharides on the bacterial cell envelope, effectively killing Gram-negative bacteria. These proteins may offer new strategies for combating multi-drug resistant superbugs.
The researchers developed a label-free multimodal microscopy platform that allows non-invasive study of cellular preparations. The platform enables the study of fine cellular processes, such as macrophage cells activation upon exposure to lipopolysaccharide (LPS), at single-cell level through phenotypic and molecular characterization.
Researchers discovered a plant immunosensor that detects lipopolysaccharide, a substance occurring in pathogenic bacteria. The LipoOligosaccharide-specific Reduced Elicitation (LORE) protein initiates an immune response in plants, similar to the toll-like receptor 4 in mammals.
Researchers found that blood clots actively soak up lipopolysaccharide, a toxic compound released by Gram-negative bacteria. This protective mechanism may help prevent disease and death from septic shock, which affects 300,000 people annually.
Researchers found that long-chain fats like oleic acid in olive oil increase intestinal absorption of pro-inflammatory lipopolysaccharides (LPS), promoting inflammation. This study suggests a potential link between dietary fat intake and inflammatory bowel disorders.