Articles tagged with Gene Clustering
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Researchers have found that elasmobranchs, including skates and sharks, lack a cluster of genes, HoxC, previously thought to be essential for proper development. This discovery challenges the assumption that all jawed vertebrates possess a full complement of nearly identical genes for critical aspects of development.
Scientists have identified a gene switch that regulates the choice of odorant receptor genes in olfactory sensory neurons. Regulatory elements in the genome act as on-off switches to determine which gene is chosen for expression.
Researchers have identified a system for targeted amplification of gene clusters in bacteria, which can significantly increase the production of antibiotics. This discovery has the potential to revolutionize the commercial production of antibiotics and may also uncover new, undiscovered antibiotics.
Researchers have discovered two gene clusters in plants producing valuable compounds, providing insights into their evolution and function. The clusters, found in dynamic regions of the genome, are maintained as a whole due to evolutionary pressure, enabling coordinated gene expression.
Researchers have expanded on existing knowledge of Alzheimer's disease by identifying a novel location within the MS4A gene cluster associated with the condition. The study suggests that the immune system plays a key role in its progression, with several genes implicated in allergies and autoimmune diseases.
Research by Dr. Inés Ibañez-Tallon and her team at MDC Berlin-Buch reveals that the midbrain habenula region plays a key role in nicotine dependence. The study found that only a balanced activity of two genes can rein in nicotine use.
A team of researchers at Vanderbilt University has discovered a large cluster of genes that appeared to jump directly from one fungus species to another, significantly strengthening the argument for a mosaic theory of evolution. The finding was made possible by comparing the genomes of nearly 100 species of fungi.
Scientists at Einstein College of Medicine discovered that genes involved in building protein complexes are activated randomly, not coordinately. This unexpected finding may change the way scientists think about cellular processes and synchronization.
Researchers at MGH-CRM and HSCI discovered that a key gene cluster is silenced in most iPSCs, limiting their developmental potential. However, some iPSC lines with the normal activation of this cluster were able to generate live animals, offering a promising approach for improving iPSC reprogramming.
Researchers found clusters of genetic markers linked to early heart attack risk, including nine genes associated with increased MI risk. The study suggests new gene sites affecting coronary heart disease and early heart attack risk, with potential for earlier intervention.
Researchers have identified a set of genes responsible for producing the deadly toxin botrydial in gray mold, and found that shutting off this gene can stop toxin production. The discovery offers hope for finding natural ways to eliminate gray mold without using expensive fungicides.
Researchers at Texas A&M University have developed a computational tool to study complex units of clustered genes called operons in bacteria. The tool allows scientists to analyze many bacterial genomes at once and is more accurate than previous methods.
Researchers have identified a plant gene cluster that produces a triterpene compound, previously unknown in plants. The study reveals how plants can assemble beneficial gene clusters to produce valuable natural products.
Researchers discovered a specific clone of bacteria responsible for most cases of Legionnaires' disease, highlighting the genetic background of Legionella pneumophila. The study found that this clone has a high prevalence in human disease due to its ability to evade host immune responses.
Scientists have identified a key gene, LaeA, that governs the mold's ability to produce toxic compounds. The discovery opens new avenues for treating Aspergillus fumigatus infection, which has a 60-90% mortality rate in immunocompromised individuals.
Researchers have successfully bred flood-tolerant California rice by introducing submergence tolerance genes into the crop. This breakthrough allows rice plants to survive short-term floods, benefiting rice farmers globally.
Researchers discover non-coding RNA transcript Kcnq1ot1 is essential for paternal-specific gene silencing in mice. The study suggests that mammals have co-opted multiple transcriptional regulatory mechanisms to control imprinted genes, supporting the idea that imprinting evolved gradually over time.
A new method has been developed to identify secondary metabolites in fungi, which are compounds that can have medicinal properties. The technique, known as genomic mining, allows researchers to pinpoint the genes responsible for producing these compounds, offering a promising tool for finding new medicines.
Researchers have discovered a new gene cluster, Rhox genes, selectively expressed in male and female reproductive tissues in adult mice. The cluster's unique expression pattern suggests its role in regulating reproduction and potentially developing new contraceptive methods.
Researchers have identified two distinct gene expression profiles in children with acute asthma, which could lead to customized treatments. The study's findings may enable targeted therapies for acute asthma attacks and help predict impending attacks by analyzing a patient's unique genetic profile.
The genomic sequence of the coelacanth, a 'living fossil,' holds valuable clues for biologists studying vertebrate evolution. The completed genome analysis reveals slow evolutionary changes relative to land vertebrates and teleost fishes, making it a better reference for comparative sequence analyses.
Researchers identified gene clusters that predict severe disease severity and location of atherosclerotic lesions in human aorta samples. The study used DNA microarray analysis to reveal 208 genes associated with severe disease and 28 genes related to disease location, showing promise for personalized medicine approaches.
Researchers identified complete set of pollen coat proteins, revealing genetic clues to plant mating and self-recognition. The study found rapid divergence of mating genes across species boundaries, shedding light on evolutionary processes.
The team designed a unique mathematical system for analyzing genetic data based on a computer algorithm that clusters information into relevant categories. The algorithm mimics unassisted learning, categorizing tissue samples into separate clusters according to their gene expression profiles.