Research on the brain basis of thinking and attention. Covers games and attention, cognitive training platforms, adaptive AI frameworks, and brain-health research.
A new Concordia study reveals that bilingualism is associated with larger and healthier hippocampi in patients with Alzheimer’s disease. The research found no evidence of hippocampal atrophy in bilinguals across the continuum of Alzheimer’s development.
Researchers developed a new algorithm to decode neural signals representing hand postures, enabling more precise control of neuroprostheses. The study, conducted on rhesus monkeys, shows that posture-related activity in the primate grasping circuit is crucial for accurate control.
A longitudinal study tracked one person's brain activity for five months, revealing how daily life affects brain function. The research found that physical activity positively influences brain regions, while subtle shifts in mood and heart rate leave lasting imprints for up to fifteen days.
A new study published in Current Biology found that our brains organize experiences into individual events based on what we currently care about and are paying attention to. The researchers used audio narratives to test this hypothesis, finding that people's brain activity creates new chapters depending on their perspective.
University of Rochester researchers have refined a noninvasive method called BL-OG that harnesses light to activate neurons in the brain. The technique has the potential to transform invasive procedures used to treat Parkinson's disease and other neurological conditions by providing a safer, less invasive alternative.
A team of scientists has successfully mapped the entire brain of Drosophila melanogaster, a fruit fly, using electron microscopy dataset and connectome analysis. The complete map will help researchers understand how different circuits work together to control behaviors like motor control, courtship, and decision-making.
Researchers successfully activated a specific memory circuit in mice using brain-imaging technology. The study found that stimulating neurons in two areas of the mouse brains reactivated spatial memory and caused the mice to seek shelter.
A recent study by the University of Trento found that newborn chicks have a population of neurons responding to face-like stimuli, suggesting an innate ability to recognize faces. This innate predisposition is supported by previous behavioural studies showing spontaneous attraction to face-like stimuli in humans and animals.
The superior colliculus, a brain region traditionally thought to control eye movements, also plays a crucial role in complex cognitive tasks like visual categorization and decision making. Research from UChicago shows that activity in this region is more involved than previously thought in guiding cognitive processes.
Researchers have developed a novel platform for testing radiation therapy effects on brain cells, providing insights into how the brain reacts to cancer treatment. The study aims to improve treatment strategies by understanding the impact of radiation on neural circuits, ultimately leading to personalized care for patients.
A new AI algorithm, DPAD, developed by Maryam Shanechi's lab, can dissociate brain patterns related to specific behaviors, improving brain-computer interfaces for paralyzed patients. The algorithm can also discover new patterns in the brain that may be missed by prior methods.
A new study from Aarhus University reveals that older individuals' brains work harder to compensate for age-related changes in memory function when listening to familiar music. The study uses classical music by Johann Sebastian Bach to map brain activity and identify potential biomarkers for dementia.
A new study using manifold learning and signal processing techniques identifies a significant correlation between adolescent brain activity and mental health symptoms. The approach, called exogenous PHATE, combines brain activation data with environmental variables to improve detection of existing symptoms and predict future ones.
A study of 500 participants from 11 countries reveals that suboptimal decisions are a universal human trait due to context influences. The researchers identified culture-specific risk preferences, with some nations exhibiting higher or lower risk-taking tendencies.
A clinical trial led by UC San Francisco aims to develop new therapies for progressive supranuclear palsy, with a focus on reducing time to find effective treatments and increasing diverse participant enrollment. The five-year grant could lead to the first effective drugs for this incurable neurodegenerative disorder.
A new study published in Frontiers in Behavioral Neuroscience has found that fans of action films and comedies react strongly to negative emotional stimuli, while those who prefer documentaries or crime films show a weaker reaction. The research suggests that people choose film genres that optimally stimulate their brains.
Researchers at EPFL developed a next-generation miniaturized brain-machine interface capable of direct brain-to-text communication on tiny silicon chips. The MiBMI system can decode neural signals generated when a person imagines writing letters or words with high accuracy and low power consumption.
A new study published in Alzheimer's & Dementia found that cholinesterase inhibitors (ChEIs) may slow down cognitive decline in dementia with Lewy bodies over five years. ChEIs were also associated with a reduced risk of death in the first year after diagnosis.
A new study by University of Waterloo researchers found that people perceive wisdom as being composed of two dimensions: reflective orientation and socio-emotional awareness. Reflective orientation includes traits like logical thinking, emotion control, and knowledge application, while socio-emotional awareness involves considering oth...
A self-guided CBT app, Maya, significantly reduced anxiety in young adults, with improvement levels similar to anxiety medication studies. The study found that the app's interactive platform and real-time feedback helped users learn new skills and coping mechanisms.
Researchers have discovered a link between cognitive impairments and brain network organization in individuals at risk of developing psychotic disorders such as schizophrenia. This finding suggests an opportunity for early diagnosis and intervention, potentially through non-invasive neuromodulation.
Researchers found that non-lawyers use complex legalese when writing laws, and it signals a sense of authority. The 'magic spell hypothesis' suggests that this style is used to convey power and legitimacy, making documents more difficult to understand.
A study found that older age, female sex, and irregular heart rhythms can predict Alzheimer's cognitive decline over two years. The results also showed strong correlations between caregiver load and various patient-related measures.
A Wayne State University research team led by Taylor Takla is studying the neural, motor, cognitive and psychological factors underlying fear of falling in multiple sclerosis patients. The goal is to break the cycle of falls, reduced physical activity and social isolation, ultimately improving quality of life for MS patients.
Researchers at WVU created a motion-compatible brain scanner that allows patients to move around during imaging. The Ambulatory Motion-enabling PET (AMPET) scanner can help study human behaviors, balance, and emotions, and may be used to monitor brain activity for PTSD treatment and mindfulness meditation.
Researchers have uncovered new insights into how the brain regulates imitative behavior, a phenomenon that facilitates interaction and social cohesion. The study used advanced brain stimulation technique to pinpoint the causal role of different circuits in facilitating or inhibiting automatic imitation.
A study published in Science Advances found that the quality of synapses, specifically dendritic spine head diameter, predicts episodic memory performance in older adults. Researchers suggest targeting pathways that maintain spine head diameter or synaptic strength may yield greater therapeutic benefits for Alzheimer's disease prevention.
Fatigue affects up to 90% of individuals with MS, significantly impacting their daily lives. The study proposes that disruptions in the cortico-striato-thalamo-cortical loop contribute to central fatigue.
Researchers found that adults prioritize cognitive cues over vocal signals when evaluating a child's intelligence or negative emotions, while vocal cues dominate for assessing happiness or helplessness. This study provides insights into the complex dynamics of caregiver-child interactions and their evolutionary roots.
Researchers developed a motor meta-learning task to assess stroke patients' ability to recognize their learning capabilities and plan practice. The study found a significant correlation between meta-learning ability and improvement index, suggesting that enhanced individual meta-learning ability can improve rehabilitation efficacy.
A recent study found that almost 50% of older adults with diabetes experienced depression during the pandemic, with loneliness and chronic pain being major risk factors. The study also identified unexpected findings, including a higher risk of depression among those with higher income prior to the pandemic.
Researchers have identified the critical step in NMDAR's routine where it rotates into an open formation, enabling electrical signals crucial for cognitive functions. This discovery may pave the way for drug compounds that can correct faulty NMDARs, potentially treating conditions like Alzheimer's and depression.
Researchers at Mayo Clinic used AI to analyze electroencephalogram (EEG) tests, identifying subtle brain wave patterns characteristic of cognitive problems like Alzheimer's disease. This technology has the potential to provide healthcare professionals with a more accessible tool for early diagnosis in communities without easy access to...
A novel study finds that monitoring cortical microstructural change in the brain using diffusion weighted MRI scans may help identify individuals at risk for cognitive decline and Alzheimer's disease. Tracking these changes over time could provide precious time for disease-modifying treatments.
Viji Santhakumar, a UCR professor, has been awarded a $3.5 million NIH grant to study brain circuit function and its impact on memory formation and cognitive deficits in diseases like epilepsy and Alzheimer's disease.
Researchers found high diagnostic accuracy for identifying Alzheimer's disease using amyloid probability score 2 blood test and p-tau217 levels. The study suggests blood tests could influence clinical care, warranting further evaluation.
α-Synuclein pathology in asymptomatic stages is linked to NBM atrophy, leading to attention/executive impairment. MRI signatures can detect this pathology in memory clinic populations.
Researchers propose a new approach to studying conscious cognitive information processing, focusing on eureka moments and learning curves. By analyzing performance over time, scientists can identify the timing of conscious processes and observe brain activity using imaging or electrophysiological methods.
A recent study published in BMC Psychology found that mild COVID-19 patients experienced significant cognitive impairment, with 11.7% showing memory loss and attention deficits. The study suggests that neuroinflammation due to SARS-CoV-2 infection may be a contributing factor to these long-term effects.
Researchers found that even those with positive attitudes towards immigrants perceive them as less competent and trustworthy than US citizens. The study used facial recognition tests to examine intergroup evaluative bias, revealing a pervasive phenomenon in the US.
Oligodendrocyte-derived amyloid beta produces toxic peptide that promotes neuronal dysfunction in Alzheimer's disease. Selective suppression of oligodendrocyte Aβ production rescues abnormal neuronal hyperactivity, suggesting targeting these cells as a promising therapeutic strategy for AD.
Researchers created a new cortical surface template called 'OpenNeuro Average' that provides greater accuracy and efficiency in analyzing neuroimaging data. The template is based on the geometric shape of the brain and can be used for studies on cognition, clinical neuroscience, autism, and neurodegenerative diseases.
A new study is testing whether digital tools can help predict which patients with depression will benefit from specific treatments and deliver them on demand. The researchers hope to use these tools to broaden access to psychiatric care and realize the promise of precision psychiatry.
Researchers used low-intensity ultrasound to target and alter the default mode network of the brain, reducing connectivity and enhancing mindfulness. The technique, called transcranial-focused ultrasound (TFUS), can induce meaningful effects with just five minutes of stimulation.
Researchers analyzed over 1.5 million patient records to find that metformin and SGLT-2 inhibitors lowered dementia and Alzheimer's disease risks compared to other antidiabetic drugs. The study suggests individualized treatment approaches considering patient-specific factors for optimal diabetes management.
By 16 months, toddlers use the left parietal cortex and both sides of the prefrontal cortex more extensively, enabling them to follow simple instructions and control impulses. The study found that brain changes occur despite no improvement in observable skills between 10 and 16 months.
A new study introduces a novel hypothesis that digital technologies affect human sociality and mental health, particularly among youth. The Disembodied Disconnect Hypothesis suggests cultivating rich personal relationships in face-to-face communities to counterbalance disembodied digital interactions.
A new study published in The Lancet found that a self-guided smartphone-based behavioral therapy led to significant improvements for patients with fibromyalgia. Stanza, a smartphone app delivering acceptance and commitment therapy, showed improved symptoms including pain intensity, fatigue, and depression.
Research reveals that pregnancy-related brain impairment affects live-bearing fish, particularly in decision-making and sensory reception. Unlike mammals, pregnant fish show decreased cell proliferation in olfactory regions, compromising scent interpretation.
Researchers discovered that young adults with higher levels of inflammation were more likely to experience reduced cognitive function in midlife. Higher inflammation was associated with lower performance on skills testing and differences in executive functioning.
Researchers have identified a cellular mechanism that detects when the brain needs an extra energy boost to support its activity. This discovery could lead to new therapies for maintaining brain health and longevity by targeting impaired brain energy metabolism, a process accelerated in ageing and neurodegenerative diseases.
A study by Waseda University researcher Ryota Nomura found that synchronized heart rates among concertgoers are linked to reliable physiological reactions rather than emotional response. This discovery could lead to better theater experiences and improved performances.
Researchers at the University of Houston have introduced a new method for sleep stage classification that can be performed at home and uses only two leads. This approach achieves expert-level agreement with the gold-standard polysomnography without expensive equipment, paving the way for more accessible and cost-effective sleep studies.
A Harvard study found that people who followed a healthy diet from their 40s onward were 43-84% more likely to be well-functioning physically and mentally at age 70 compared with those who did not. Adhering to diets rich in fruits, vegetables, whole grains, and healthy fats was associated with greater odds of healthy aging.
A recent study found that consuming isoflavones from soy foods improves thinking abilities and attention in school-aged children. The researchers analyzed data from 128 children aged 7-13 and found that those who consumed more soy foods showed faster response times during attentional tasks.
A new study of over 3,000 people found that dietary quality was closely linked with trends in general cognitive ability, with those eating more recommended foods showing improved cognitive performance and reduced risk of dementia. Establishing healthy dietary patterns early in life may support brain health throughout life.
A new study creates a framework to reduce confusion around fish consumption during pregnancy and provide clearer guidance on risks and benefits. The research found that consuming low-mercury fish was beneficial, while high-mercury fish was detrimental to neurodevelopment.
A pilot study found that remote cognitive rehabilitation using TELE-Self-GEN improved memory performance and daily life functionality in individuals with MS. The virtual intervention demonstrated high levels of participant satisfaction and effectiveness.
Nerve cells in the hippocampus region of the bat brain encode information on multiple characteristics of other individuals, including sex and dominance hierarchy. This study sheds light on how the brain operates and generates thinking processes and behavior.
A recent study found that vaccination can reduce cognitive symptoms, including memory loss, after SARS-CoV-2 infection. Researchers identified IL-1β as a potential mechanism driving cognitive impairment and showed that prior vaccination reduced inflammation and lowered levels of this cytokine protein.