Researchers found that high levels of both amyloid and tau proteins impair memory functions, but only when amyloid burden is also high. The study suggests that anti-amyloid therapies may be beneficial in reducing memory impairment in the early stages of Alzheimer's disease.
Brainwide association studies need thousands of individuals to yield higher reproducibility, as smaller samples often uncover strong but spurious associations. Larger sample sizes lead to more likely reproductions of correlations, with effect sizes decreasing as the number of participants increases.
A large-scale study aims to understand how individual brains change over time, identifying factors that increase cognitive decline risk and those that confer resilience. The Adult Aging Brain Connectome study will follow 1,000 participants across a decade, collecting brain scans, blood samples, and demographic data.
A study by UC Davis MIND Institute researchers found that autistic children have distinct amygdala changes, with larger volumes associated with traditional anxiety and smaller volumes linked to autism-distinct anxieties. The study used brain scans of 71 autistic and 55 non-autistic children between ages 2-12.
The new sensor grids offer 100 times higher resolution than existing technology, allowing for more precise identification of seizure origins and preservation of healthy brain tissue. Longer term, the technology holds potential for permanent implantation to improve life quality for people with paralysis or neurodegenerative diseases.
Studies using virtual reality environments revealed that individuals with anxiety disorders exhibited increased brain activity in response to perceived threats, even in safe areas. The findings highlight the need for personalized treatments that help patients regain control over their body.
Researchers at the University of Toronto have demonstrated that listening to personally meaningful music induces beneficial brain plasticity in patients with mild cognitive impairment or early Alzheimer's disease. The study showed changes in neural pathways correlated with increased memory performance on neuropsychological tests, suppo...
Georgia State University researcher Vince Calhoun has received a $3.5 million grant to develop new methods for capturing dynamic connectivity in the brain and identifying biomarkers for early detection of Alzheimer's disease. The researchers aim to analyze real-time connectivity patterns to predict future cognitive decline.
A recent study found COVID-19 survivors exhibit abnormal patterns of brain connectivity associated with increased post-traumatic stress symptoms. The research team discovered three distinct states of functional connectivity in the brains of COVID-19 survivors, which are linked to symptom severity.
A Wayne State University researcher is applying topological data analysis to functional magnetic resonance imaging (fMRI) data to discover hidden brain structures. This collaboration aims to provide medical researchers with new tools for analyzing complex fMRI data.
A larger sample size failed to support original claims linking genetic variants to altered brain activation during reading and listening. The new findings highlight the complexity of genes and human brain function relationships.
Research reveals that prenatal organophosphate exposure is associated with decreased brain activity in adolescents, particularly in regions related to cognitive and language functions. The study also identifies sex-dependent differences in brain activation patterns following OP exposure.
The Hastings Center special report examines the capabilities and limitations of neuroimages in biomedical research, medicine, and courtrooms. Key findings include concerns about overinterpretation, misapplication, and the lack of direct neural activity shown by neuroimaging techniques.