Articles tagged with Blood
A multi-institutional study found that extended use of anti-clotting drug enoxaparin significantly reduced the chances of blood clots in bedridden patients, especially those over 75 and female. The treatment also increased bleeding risk slightly.
The Cedars-Sinai Heart Institute has received a $1.66 million grant to develop a measurement system predicting patient vulnerability to sudden cardiac arrest. The study aims to identify patients at high risk of sudden cardiac arrest by analyzing electrocardiogram data.
Researchers at The Chinese University of Hong Kong have identified biomarkers in preterm infants' blood that can detect late-onset septicemia and necrotizing enterocolitis. These findings may help diagnose preterm infants requiring urgent treatment, reducing the risk of life-threatening conditions.
A randomized study found that inhaled insulin plus insulin glargine achieved similar blood sugar control as twice-daily premixed biaspart insulin, with less weight gain and hypoglycemia. The treatment also showed a better safety profile, with fewer cough and lung function issues.
A new study of 1,960 White-Americans and 368 Black-Americans with VTE found that Blacks had a significantly higher proportion with pulmonary embolism and idiopathic PE, as well as a higher incidence of VTE. The study suggests that true causes for these racial differences remain unknown and warrant further investigation.
Researchers analyzed bed bug saliva proteins to understand their role in feeding and potential medical applications. The study found unique enzymes that characterize the saliva profile of Cimex lectularius, a blood-feeding insect with over 250 million-year survival success.
A new study finds women with polycystic ovary syndrome (PCOS) have higher bisphenol A (BPA) blood levels, associated with increased male hormones and reproductive problems. The study suggests that women with PCOS should limit their exposure to BPA due to its potential adverse effects on hormone balance.
Researchers at Saint Louis University have successfully engineered a new version of the blood-regulator enzyme thrombin with optimized anti-blood clotting properties. This breakthrough opens the door to potential new medications that can treat diseases related to thrombosis without carrying a risk of hemorrhage.
The Lancet Editorial calls on Google and Facebook to promote safe lifestyles and encourage young people to donate blood. Harnessing the internet's power could boost blood supplies by recruiting a new generation of late teens and 20-year-olds.
Researchers found similar leukaemia-free survival rates for unrelated cord blood transplants and matched bone marrow or peripheral blood progenitor cell transplants. UCB transplantation was also linked to lower rates of acute and chronic graft-versus-host disease.
Research suggests that abnormalities in blood clot formation contribute to AD pathogenesis. A new therapeutic strategy aims to slow cognitive decline by targeting altered blood clotting caused by amyloid peptide.
A study by Max-Planck-Gesellschaft researchers found that House sparrow males' bill color is correlated with their testosterone levels, while the size of their badge has no such correlation. This suggests that the badge may be an honest signal of a male's quality rather than his dominance status.
A study found that patients with excessive oxygen levels in arterial blood following cardiac arrest have a higher rate of death in the hospital. Hyperoxia was associated with significantly higher in-hospital mortality compared to normoxia.
Three new oral blood-thinning drugs may offer significant advantages over Coumadin, but their lack of clinical experience raises concerns about potential interactions. Many adults take multiple prescription drugs, increasing the risk of adverse interactions.
Researchers at Henry Ford Hospital found that a continuous flow left ventricular assist device (LVAD) improves function on the right side of the heart, reducing central venous pressure and pulmonary artery pressures. The study, which monitored 41 patients, also showed significant improvements in measures related to tricuspid regurgitat...
A large population-based study found a small increase in heart disease risk linked to higher blood sugar levels, but the changes were not substantial. The researchers confirmed their findings in a systematic review of existing literature.
Pioneering AIDS researchers Dr. Mark Wainberg and Dr. Norbert Gilmore argue that the current ban on gay men donating blood is no longer justified. They suggest allowing only those in stable, long-term monogamous relationships to donate, while maintaining the ban on those with multiple partners.
The Canadian Medical Association Journal suggests relaxing the ban on male blood donors who have had sex with men, citing a significant decrease in false negative test results. The proposed change could lead to an expansion of the blood donor pool, resulting in more units of blood available for transfusions.
A new blood test can predict whether newborn babies are at high risk of developing allergies as they grow older, thanks to research involving the University of Adelaide.
A large trial found that adding misoprostol to standard uterotonics did not reduce post-partum blood loss, but was associated with increased shivering and body temperature. WHO's withdrawal of support for misoprostol use in low-income settings has been criticized.
Researchers at Stanford University School of Medicine discovered a previously unknown association between type-2 diabetes and high levels of polychlorinated biphenyls and gamma-tocopherol, a form of vitamin E. The novel analytic technique, called environment wide association studies (EWAS), identified these relationships surpassing tho...
A study by UC Davis researchers has identified a blood component, lipoprotein-associated phospholipase A2 (Lp-PLA2), as a predictor of coronary artery disease in African-Americans. The finding highlights the role of inflammation in vascular disease among this ethnic group and may lead to more targeted treatment approaches.
Researchers discovered that adding proline and phenylalanine amino acids improves binding rates of synthetic fibrin knobs to holes, leading to a novel peptide mimic with 10-fold higher affinity. The study also identified structural properties contributing to functional knob-hole interactions.
A new study by Stanford researchers highlights the need for standardized criteria in diagnosing food allergies due to differing definitions and inconsistent treatment approaches. This could lead to misdiagnosis and unnecessary anxiety for patients with food intolerance, while also potentially overdiagnosing food allergies.
A pooled analysis of 25 trials found that consuming an average of 67 grams of nuts per day resulted in a 5.1% reduction in total cholesterol, 7.4% decrease in LDL-cholesterol, and 8.3% change in HDL-cholesterol levels.
A joint clinical trial found that administering fibrinogen before heart surgery reduces bleeding risk. The study suggests fibrinogen concentrate could be used as a preventive therapy for patients undergoing cardiac surgery.
Researchers presented studies on predicting pregnancy-associated breast cancer, post-traumatic stress disorder in breast cancer patients, and novel drug candidates such as flavaglines. The conference also explored the use of circulating tumor cells and gene differences to predict survival outcomes in breast cancer patients.
Genetic research suggests that elevated triglyceride levels are associated with a higher risk of heart disease. A major international consortium led by Dr Nadeem Sarwar and Professor John Danesh found this link in analysis of 350,000 people from 101 studies.
A North Carolina State University researcher found that bacteria from insect bites can be passed to human babies by the mother, causing chronic infections. The study suggests a possible link between maternal infection with bacteria like Bartonella and birth defects.
A national study suggests that the standard heel-stick test is not effective at identifying cytomegalovirus (CMV) infection in newborns, with only 17 out of 60 infected children identified. The test's limited value has major public health implications, as congenital CMV infection is a leading cause of hearing loss in children.
Researchers at Children's National Hospital found that carbon monoxide levels increase during routine general anesthesia in young children. To reduce this risk, anesthesiologists recommend using specific absorbents and avoiding low-flow anesthesia to minimize exposure.
Research found that long-term anabolic steroid users had weaker left ventricle function and impaired diastolic function compared to non-steroid users. Eighty-three percent of steroid users had low ejection fraction, linked to increased risk of heart failure and sudden cardiac death.
Researchers found that men with metabolic syndrome had twice as low blood H2S levels as lean men, while those with diabetes had four times lower levels. This reduction in H2S was associated with higher blood pressure, increased insulin resistance and damage to small blood vessels.
A new blood test has reduced the number of biopsies performed on heart transplant patients by 50% in a landmark Stanford study. The test uses genomics technology to identify patients at low risk for rejection, allowing doctors to safely reduce biopsy frequency and improve patient quality of life.
A new study reveals that individual fibrin fibers play a crucial role in equitably distributing strain load and strengthening the entire network. The research found that fibers subjected to significant strain stiffen to resist stretch, thereby reducing strain concentrations.
Researchers at the University at Buffalo found that vitamin D supplements, diet, geographic location, demographic information, and lifestyle cannot accurately predict vitamin D concentrations in blood. This means that relying on proxy measures like food intake or latitude of residence to assess cancer risk is not reliable.
A blood test measuring C-reactive protein (CRP) levels may help assess colon cancer risk, according to a Vanderbilt University Medical Center study. High CRP levels were found to be associated with a 2.5-times greater risk of colon cancer in women.
A study found that the traditional 'heel stick' test is not an effective screening tool for cytomegalovirus (CMV) infection in newborns. The test, which involves pricking a baby's heel and analyzing dried blood samples, was unable to detect CMV DNA in up to 40% of infected babies.
A study found that DNA analysis of dried blood samples from newborns did not effectively identify an infection causing congenital CMV, leading to sensorineural hearing loss. Current methods for screening newborns for this infection have low sensitivity and specificity.
A $3.7 million clinical trial will evaluate customized warfarin dosage based on patient genetics to balance blood clotting risks and benefits in orthopedic patients. The study aims to identify the optimal range of blood clotting speed, using genetic formulas to refine warfarin dosing.
A new mobile compression device has been shown to be as effective as medication in preventing blood clots after hip replacement surgery, with greater patient safety. The device reduces the risk of clot formation by maximizing blood flow and is comparable in cost to traditional blood thinners.
Two transplant centers report successful paired donor exchanges for living donor liver transplantation (LDLT) in ABO-incompatible cases. The program allows for compatible but unrelated donors to donate, enabling recipients to undergo LDLT with high success rates.
The WPI research team aims to develop powerful diagnostic tools that can predict the likelihood of plaque rupture, which is responsible for most heart attacks and strokes. The new NIH award will enable the team to extend their research on arterial plaque development and predict potential rupture.
Researchers at Penn State College of Medicine have identified a set of 17 proteins in the blood that accurately predict alcohol usage 90% of the time. These proteins can distinguish between excessive and responsible drinking levels, offering a potential diagnostic test for alcohol consumption.
Researchers at the University of Edinburgh identified three genes that contribute significantly to blood clotting speed in healthy individuals. These findings may help further understanding and treatment of conditions like deep vein thrombosis, heart attacks, and bleeding disorders.
Researchers have identified a key enzyme, myeloperoxidase, as a significant predictor of mortality in Coronary Artery Disease (CAD) patients. High levels of the enzyme increase the risk of death by more than double over a 13-year period.
Scientists found that a protein barrier in mosquito midgut prevents disease-causing agents like the Plasmodium malaria parasite from infecting mosquitoes. Disrupting this barrier could trigger immune defenses to protect insects from infection, potentially informing new strategies for blocking malaria transmission.
A clinical trial conducted by researchers from Karolinska Institutet found that eprotirome, a thyroid-hormone-like substance, effectively reduces blood cholesterol levels in patients who have already received statins. The trial showed significant reductions in harmful blood fats, up to 30% lower than those of patients receiving a placebo.
Researchers at the US Department of Agriculture's Agricultural Research Service (ARS) have discovered how the yellow-fever-transmitting Aedes aegypti mosquito detects the specific chemical structure of octenol, a compound emitted by mammals. The study shows that mosquitoes tap into the 'handedness' of molecules to detect this compound.
Researchers at Cornell University have identified a protein involved in mosquito urination, which can help control the spread of diseases like dengue fever. By blocking this protein's function, mosquitoes may be limited in their ability to survive after feeding on blood.
A University of Alberta researcher has identified a way to lower the amount of fat in the blood and improve glucose metabolism. The study found that decreasing the activity of an enzyme called triacylglycerol hydrolase (TGH) can also protect against diabetes and increase physical activity.
Researchers created a risk assessment method based on race, Medicaid eligibility, and neighborhood characteristics, which identified even more high-risk children than current methods. The new approach could save taxpayers $153,000 by reducing unnecessary lead poisoning tests.
A new study by Northwestern University recommends raising pregnancy blood sugar levels to nearly double the risk of complications for mothers and babies. The revised guidelines suggest that a fasting blood sugar level of 92 or higher poses serious risks to both mother and baby.
A team at Washington University in St. Louis has identified a link between white-tailed deer populations and emerging tick-borne diseases, including human ehrlichiosis and southern tick-associated rash illness (STARI). The study used a sophisticated DNA assay to track the transmission of pathogens from wildlife to ticks.
A study found that 79% of dialysis patients were vitamin D deficient, with black race, female sex, and winter season being strong predictors. Low blood albumin levels may lead to protein loss in the urine, affecting vitamin D transport.
Researchers have found a potential way to reduce brain damage caused by strokes using a simple blood-pressure cuff. By applying brief periods of high pressure to the arm, the goal is to prepare the brain for reduced blood flow without lasting damage.
The University of Cincinnati researchers will investigate ways ILD appears in patient groups with autoimmune diseases and develop more efficient diagnosis and treatment methods. The study aims to identify specific biomarkers and medical records characteristics that predict the best treatment outcomes for ILD patients.
Researchers at Johns Hopkins have developed a new approach to detect cancer using whole genome sequencing, identifying rearrangements of DNA that can be found in tumor cells. This approach, called Personalized Analysis of Rearranged Ends (PARE), may help clinicians tailor treatments and monitor tumor levels after therapy.
Fatal car crashes among young female drivers in the US have seen a rise in alcohol-related incidents, with rates among young men declining over the study period. Notably, young women's rates were lower but showed less predictable patterns, including an increase in positive blood tests at certain ages and times of the week.
Researchers found that patients with a low ejection fraction in the right ventricle had a significantly increased risk of death. The study suggests that measuring RVEF can help identify high-risk patients and improve treatment outcomes.