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Life Sciences

Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.

447,757 articles | 2542 topics

Health and Medicine

Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.

431,843 articles | 751 topics

Social Sciences

Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.

260,756 articles | 745 topics

Physical Sciences

Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.

257,913 articles | 1552 topics

Applied Sciences and Engineering

Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.

225,386 articles | 998 topics

Scientific Community

Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.

193,043 articles | 157 topics

Space Sciences

Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.

29,662 articles | 175 topics

Research Methods

Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.

21,889 articles | 139 topics

Mathematics

Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.

3,023 articles | 113 topics

Long-term brain structure and cognition following bariatric surgery

Researchers found that bariatric surgery led to improved cognition and overall well-being two years after the procedure. The study revealed changes in blood vessel efficiency and cortical thickness of the temporal cortex, offering new treatment options for patients with obesity and dementia.

Resolution time of COVID vaccine-related lymphadenopathy

A study published in AJR found that COVID-19 mRNA vaccination-induced axillary lymphadenopathy resolves after a mean of 97 days. Longer resolution times were observed with Moderna vaccination, receipt of second doses, and thicker cortical thickness at presentation.

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Manic episodes in bipolar disorder linked to abnormal brain changes

Patients with bipolar disorder experiencing manic episodes show abnormal brain changes, including faster cortical thinning, compared to those without episodes. The study also found associations between brain ventricle enlargement and accelerated cognitive decline in bipolar patients.

Development of cortical thickness in infants

Researchers studied cortical thickness in 43 infants over two years, finding it increases rapidly until 14 months. Each developmental region of thickness was functionally important, with some continuing to thicken beyond 2 years.

Brain thickness provides insight into teenage decision-making

A study of adolescents found that thinner brain cortex regions are associated with more impulsive decision-making. Cortical thickness predicted delay discounting, a measure of impulsivity related to the value of rewards, above cognitive and demographic variables.

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Imaging shows impact of PTSD in earthquake survivors

A new study using MRI found that adult earthquake survivors with post-traumatic stress disorder (PTSD) had greater cortical thickness in certain brain regions and reduced volume in others compared to healthy survivors. Cortical thickness was positively correlated with PTSD severity, particularly in the left precuneus region.

Thickness of grey matter predicts ability to recognize faces and objects

A new study found that the thickness of the cortex in the fusiform face area (FFA) can predict a person's ability to recognize faces and objects. The researchers discovered an inverse relationship between FFA cortical thickness and visual expertise, with thicker FFA cortex linked to better non-face recognition.

New study explains cognitive ability differences among the elderly

A new study published in Molecular Psychiatry found that childhood cognitive ability accounts for more than two-thirds of the association between cognitive ability and cortical thickness in old age. The research used standardized intelligence tests and MRI brain scans to compare the results of 588 people taken at different ages.

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MRI shows brain abnormalities in migraine patients

Research suggests that migraines are related to brain abnormalities present at birth and others that develop over time. Cortical thickness and surface area abnormalities were found in regions related to pain processing, with minimal overlap between the two types of abnormalities.

Smoking may thin the brain

A new study finds that smoking is associated with reduced cortical thickness in the left medial orbitofrontal cortex, negatively correlating with cigarette consumption. Heavier smoking was linked to more pronounced thinning of cortical tissue, potentially increasing the risk for addictions and cognitive decline.

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When it comes to intelligence, size matters

A collaborative study by McGill University researchers discovered a positive correlation between cognitive ability and cortical thickness in the brains of healthy 6 to 18-year-olds. The link was found in regions integrating information from different parts of the brain, including 'multi-modal association' areas.

Study finds abnormalities in cerebral cortex of cocaine addicts

A brain imaging study found cocaine addicts exhibit reduced cortical thickness in areas responsible for attention and reward-based decision-making. The study suggests a mixture of drug effects and predisposition underlying these structural alterations, with potential implications for prevention efforts.

Meditation associated with increased grey matter in the brain

A study found that regular meditation practice is associated with increased thickness in certain cortical regions related to sensory perception, auditory processing, and attention. The researchers also discovered that meditation may slow age-related thinning of the frontal cortex.