A new USC-led study found a significant link between type 2 diabetes and cortical thickness in older adults from various populations. The researchers discovered that individuals with T2DM exhibited thinner cortex, particularly in temporal and parietal regions critical for memory and cognitive function.
SourceKeck School of Medicine of USC·JournalAlzheimer s & Dementia Diagnosis Assessment & Disease Monitoring·TypeImaging analysis·DateMay 15, 2025
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Researchers found that bariatric surgery led to improved cognition and overall well-being two years after the procedure. The study revealed changes in blood vessel efficiency and cortical thickness of the temporal cortex, offering new treatment options for patients with obesity and dementia.
SourceJAMA Network·JournalJAMA Network Open·DateFeb 9, 2024
A new study by an international group of researchers has found substantial reductions in grey matter in people with anorexia nervosa, a condition characterized by severe food restriction and low body weight. Early intervention and treatment can help the brain repair itself, according to the research team led by Dr. Paul M. Thompson.
SourceKeck School of Medicine of USC·JournalBiological Psychiatry·TypeMeta-analysis·DateJun 14, 2022
A study published in AJR found that COVID-19 mRNA vaccination-induced axillary lymphadenopathy resolves after a mean of 97 days. Longer resolution times were observed with Moderna vaccination, receipt of second doses, and thicker cortical thickness at presentation.
SourceAmerican Roentgen Ray Society·JournalAmerican Journal of Roentgenology·TypeObservational study·DateMay 20, 2022
Patients with bipolar disorder experiencing manic episodes show abnormal brain changes, including faster cortical thinning, compared to those without episodes. The study also found associations between brain ventricle enlargement and accelerated cognitive decline in bipolar patients.
SourceKarolinska Institutet·JournalBiological Psychiatry·TypeImaging analysis·DateSep 16, 2021
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Two studies indicate that WTC responders are at risk for developing dementia, with reduced gray matter thickness in the brain consistent with neurodegenerative conditions. Researchers found protein changes in blood consistent with Alzheimer's disease in responders with PTSD and mild cognitive impairment.
Researchers studied cortical thickness in 43 infants over two years, finding it increases rapidly until 14 months. Each developmental region of thickness was functionally important, with some continuing to thicken beyond 2 years.
SourceProceedings of the National Academy of Sciences·JournalProceedings of the National Academy of Sciences·DateJul 22, 2019
A recent study found that increased fetal exposure to folic acid due to grain fortification is associated with altered postnatal brain development and psychiatric risk in youth. Cortical thickness on MRI scans revealed significant changes, highlighting the need for further research into micronutrient effects on brain development.
SourceJAMA Network·JournalJAMA Psychiatry·DateJul 3, 2018
A study of adolescents found that thinner brain cortex regions are associated with more impulsive decision-making. Cortical thickness predicted delay discounting, a measure of impulsivity related to the value of rewards, above cognitive and demographic variables.
A recent study from the Center for BrainHealth found that strategic brain training positively affects neural connectivity for individuals with TBI. The research challenges the widely held belief that recovery from a TBI is limited to two years after an injury.
SourceCenter for BrainHealth·JournalBrain and Behavior·DateMay 23, 2017
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A new study from the University of Cincinnati reveals that former college football players continue to show evidence of neuropathic brain changes several years after graduation. The research found lower cortical thickness in areas critical for attention, memory, and executive abilities.
SourceUniversity of Cincinnati·JournalClinical Journal of Sport Medicine·DateNov 30, 2016
A new study using MRI found that adult earthquake survivors with post-traumatic stress disorder (PTSD) had greater cortical thickness in certain brain regions and reduced volume in others compared to healthy survivors. Cortical thickness was positively correlated with PTSD severity, particularly in the left precuneus region.
SourceRadiological Society of North America·JournalRadiology·DateMar 1, 2016
A new study found that the thickness of the cortex in the fusiform face area (FFA) can predict a person's ability to recognize faces and objects. The researchers discovered an inverse relationship between FFA cortical thickness and visual expertise, with thicker FFA cortex linked to better non-face recognition.
SourceVanderbilt University·JournalJournal of Cognitive Neuroscience·DateNov 9, 2015
A new study published in Molecular Psychiatry found that childhood cognitive ability accounts for more than two-thirds of the association between cognitive ability and cortical thickness in old age. The research used standardized intelligence tests and MRI brain scans to compare the results of 588 people taken at different ages.
SourceMcGill University·JournalMolecular Psychiatry·DateJun 4, 2013
Research suggests that migraines are related to brain abnormalities present at birth and others that develop over time. Cortical thickness and surface area abnormalities were found in regions related to pain processing, with minimal overlap between the two types of abnormalities.
SourceRadiological Society of North America·JournalRadiology·DateMar 26, 2013
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Researchers have found that chronic drinking leads to reduced cortical thickness in frontal and temporal brain regions, affecting cognitive abilities and intellectual functions. The study's results indicate that alcohol damage occurs in gradations, with more severe damage associated with higher levels of consumption.
SourceAlcoholism: Clinical & Experimental Research·DateSep 15, 2011
Researchers at Wayne State University have found a new method to identify children with major depressive disorder (MDD), setting them apart from both healthy children and those with obsessive compulsive disorder (OCD). Cortical thickness in the brain was used as a key factor, revealing distinct differences between MDD patients and heal...
SourceWayne State University - Office of the Vice President for Research·JournalArchives of General Psychiatry·DateMay 10, 2011
A new study finds that smoking is associated with reduced cortical thickness in the left medial orbitofrontal cortex, negatively correlating with cigarette consumption. Heavier smoking was linked to more pronounced thinning of cortical tissue, potentially increasing the risk for addictions and cognitive decline.
SourceElsevier·JournalBiological Psychiatry·DateDec 2, 2010
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A collaborative study by McGill University researchers discovered a positive correlation between cognitive ability and cortical thickness in the brains of healthy 6 to 18-year-olds. The link was found in regions integrating information from different parts of the brain, including 'multi-modal association' areas.
SourceMcGill University·JournalIntelligence·DateMar 25, 2009
A brain imaging study found cocaine addicts exhibit reduced cortical thickness in areas responsible for attention and reward-based decision-making. The study suggests a mixture of drug effects and predisposition underlying these structural alterations, with potential implications for prevention efforts.
SourceMassachusetts General Hospital·JournalNeuron·DateOct 8, 2008
A study found that regular meditation practice is associated with increased thickness in certain cortical regions related to sensory perception, auditory processing, and attention. The researchers also discovered that meditation may slow age-related thinning of the frontal cortex.
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