Articles tagged with Sweat Glands
Researchers have identified a genetic driver of primary idiopathic hyperhidrosis, a chronic condition causing excessive sweating. The discovery suggests that the disorder can originate in the nervous system and may be treatable with targeted therapies.
Researchers have successfully regenerated human epidermal keratinocytes into sweat gland-like cells using a combination of chemicals. These cells, called ciSGCs, restored thermoregulatory sweating and released bioactive factors to stimulate tissue repair in burned skin.
A new study by Arizona State University reveals that initial phase sweating can be three times more effective than later phase sweating in terms of evaporation. The researchers developed a wind tunnel-shaped capsule with high-magnification video imagery to capture the dynamics of sweat droplet formation and evaporation on human skin.
Researchers investigated molecular changes in aging mouse sweat glands, finding 171 mRNAs enriched in secretory cells. Altered mRNA and protein abundance were associated with age-related declines in sweat gland function.
Researchers at Osaka Metropolitan University developed a lysin from a bacteriophage that targets Staphylococcus hominis, a key contributor to body odor. The study's results could lead to a new treatment option for axillary odors, a common dermatological disorder.
Researchers identified distinct genomic characteristics that impact prognosis for patients with triple negative apocrine carcinoma. The study confirmed a five-year disease-free survival rate of 92.2% for these patients, significantly higher than those diagnosed with other types of TNBC.
Researchers developed a new type of wearable sweat sensor that can analyze sweat for vital signs like dehydration and blood sugar levels. The device, called the 'sweatainer,' offers a glimpse into the future of health monitoring with its non-invasive technology.
Researchers have developed a battery-free biosensor that can track glucose levels in sweat using radio frequency signals. The device, resembling a smart necklace, showed promising results in monitoring glucose levels during exercise and has potential applications for detecting other biomarkers in bodily fluids.
A Bar-Ilan University study reveals a correlation between physiological data collected prior to the pandemic and heightened COVID-related fears. The research found that individuals with larger households and those who experienced financial difficulties during the pandemic were more likely to exhibit elevated worries.
A Bar-Ilan University study found that individuals with more relaxed heart rate/respiratory function 2-3 years prior to SARS-CoV-2 reported greater mental well-being during the pandemic. Physiological measures such as RSA and SCL were used to assess individuals' mental well-being and regulation of negative emotions.
Researchers analyzed DNA repair targeting in cutaneous apocrine sweat gland carcinoma (CAC) cells with a PALB2 aberration. They found sensitivities to BET-bromodomain inhibition and modest sensitivity to DNA-PKi, ATRi, WEE1i, and PARPi. The study also identified a potential therapeutic opportunity for targeting PALB2 deficient cells th...
Researchers discovered that humans evolved higher eccrine gland density due to accumulated changes in the hECE18 enhancer region, which drives EN1 expression. This trait is thought to have adapted to early hominins' hot habitats, promoting survival and evolution.
A study reveals that fingerprints facilitate grip by controlling friction through the interaction of sweat glands and moisture. The researchers found that fingerprint ridges effectively block sweat glands when in contact with a surface, resulting in maximum friction.
Researchers found that tattooed skin has reduced sweat rates, which can lead to increased risk of overheating. The study suggests that the tattooing process damages eccrine sweat glands, potentially causing long-term complications.
Osaka University researchers have generated immortalized human eccrine sweat gland myoepithelial cells (iEM cells), which can be cultured for over ten generations. This achievement has the potential to develop next-generation antiperspirants and promote research on sweat dysfunction and regeneration.
A Japan first! Osaka University researcher Kie Nakashima won the Academic Prize at Cosmetic Victories 2019 for proposing a new concept for next-generation antiperspirants that directly act on sweat glands. This innovation aims to suppress sweating by making sweat glands inactive, not by plugging their exits.
The study sheds light on the functions of sweat gland components, revealing key roles for myoepithelial cells and nerve interactions. The findings have implications for treating disorders of the perspiratory system and could lead to new treatments for heatstroke.
Researchers identify opposing signaling pathways that determine the formation of hair follicles and sweat glands in humans, similar to mice but separated by time. This discovery has potential to improve methods for culturing human skin tissue used in grafting procedures.
Researchers found that sweat glands contribute less cells to wound closure in elderly skin, leading to delayed healing and thinner repaired epidermis. Chronic sun exposure damages skin structures supporting sweat glands, highlighting the importance of sunscreen use.
A large study found that hidradenitis suppurativa is associated with a higher risk of adverse cardiovascular outcomes and death from all causes. Patients with HS were found to have a higher risk of cardiovascular-associated death compared to those with severe psoriasis. The study suggests greater awareness is needed for this association.
A rare genetic disorder called anhidrosis has been linked to a mutation in the ITPR2 gene, which controls calcium release in sweat glands. The study, led by Katsuhiko Mikoshiba and Niklas Dahl, found that a single nucleotide change in the DNA code impairs sweat production, leading to hyperthermia risk.
A recent study published in PLOS ONE reveals that sweat gland stem cells have the ability to differentiate into multiple cell types, including hair follicles and skin layers. This discovery offers exciting possibilities for developing stem cell-based treatments for conditions like hyperhidrosis and hypohidrosis.
A new study finds that stress sweat significantly impacts social judgments of one's confidence, trustworthiness, and competence in both males and females. The study, published in PLOS ONE, reveals that the odor from stress-related sweat affects how women are perceived by others.
A recent study using an animal model revealed that a single genetic mutation led to several common traits in East Asian populations, including thicker hair and denser sweat glands. The researchers found that the mutation is at least 15,000 years old and emerged around 30,000 years ago in central China.
A team of researchers created an animal model of recent human evolution, revealing a single mutation that produced several traits common in East Asian peoples. The study found that the mutation arose around 30,000 years ago in central China and is linked to thicker hair, denser sweat glands, and other skin features.
Researchers found that eccrine sweat glands store adult stem cells that can quickly aid wound healing. This discovery advances understanding of the normal healing process and paves way for designing better targeted therapies.
Scientists have identified a rare genetic mutation that underlies adermatoglyphia, a condition characterized by the complete absence of fingerprints. The study provides valuable insight into the genetics of fingerprint formation and highlights the usefulness of rare genetic mutations in understanding human biology.
Rates of cancers affecting skin appendages such as sweat glands and mammary glands are rising in the US. Incidence increased by 150% between 1978-1982 and 2002-2005, with age being a key factor.
A groundbreaking study published in the journal Pain reveals that humans have a unique sensory system located in blood vessels and sweat glands, which can provide conscious tactile information. This discovery may contribute to understanding mysterious pain conditions such as migraine headaches and fibromyalgia.
The study identified the gene responsible for producing ear wax as being located on chromosome 16, near another gene linked to paroxysmal kinesigenic choreoathetosis. This discovery may shed light on the development of apocrine glands and their secretory products.