Articles tagged with Antioxidants
Researchers found that resveratrol induces pancreatic cancer cell death by crippling the mitochondria's energy function, leading to apoptosis. The study suggests that moderate red wine consumption may not be contraindicated during chemotherapy or radiation treatment.
A study found that variations in the PON1 gene and its related enzyme activity increase cardiovascular disease risk, with higher PON1 activity linked to lower major adverse cardiac event rates. The researchers also discovered a dose-dependent association between PON1 gene polymorphisms and increased oxidative stress levels.
A double-blind study found Pycnogenol improved both numerical and spatial working memory in senior citizens. The antioxidant extract reduced oxidative stress markers, indicating a potential role in preserving or enhancing mental functions.
A UCLA study found that broccoli's sulforaphane can switch on antioxidant genes and enzymes in immune cells, combating oxidative tissue damage. This could lead to a decline in age-related decline in immune function.
A recent study published in the Journal of Agriculture and Food Chemistry found that POM Wonderful 100% Pomegranate Juice has superior antioxidant power compared to other beverages. The juice ranked higher than red wine, Concord grape, blueberry, and orange juices in terms of phenolic content and antioxidant activity.
Researchers at Yale School of Medicine discovered a significant association between low vitamin E levels and physical decline in older adults. The three-year study found that individuals with lower vitamin E levels experienced a 62% greater risk of declining in physical function.
Women with higher dietary intakes of lutein, zeaxanthin, and vitamin E have a lower risk of developing cataracts. These antioxidants may protect against cataract formation by filtering harmful blue light and damaging lens proteins.
A recent study by Dr. Shiow Y. Wang found that seven types of wild strawberries contain higher antioxidant levels and more potential to reduce cancer risk. The antioxidants in these 'super seven' strawberries may be useful in developing cultivars with greater anticancer potential.
A new study by University of Illinois researchers found that grape-seed extract is a viable natural alternative to synthetic ingredients for preserving meat quality in pre-cooked meals. The extract's phenolic compounds have been shown to be effective antioxidants in slowing the oxidation of fats.
A study by Purdue University found that citrus juices and vitamin C enable more of green tea's unique antioxidants to remain after digestion. The researchers discovered that lemon juice had the most profound impact, followed by orange, lime, and grapefruit juices.
A study found that long-term beta carotene supplementation significantly improved cognitive function in men, with a potential to prevent dementia. The study suggested that antioxidant supplements like beta carotene may provide neuroprotection against age-related cognitive decline.
David Farb's abstract details how antioxidants affect dopamine release from synaptosomes, suggesting potential for treating oxidative damage in neurodegenerative diseases. Antioxidants like glutathione and NAC may rapidly stabilize dopamine release, raising their therapeutic potential.
Researchers found that breakdown of chlorophyll in ripening fruits produces highly active antioxidants called nonfluorescing chlorophyll catabolytes (NCCs). These NCCs are effective against oxidative stress and may play a role in human health. The study suggests that consuming ripe fruits regularly can provide potential health benefits.
A Johns Hopkins study found that vitamin C and other antioxidants can inhibit the growth of some tumors in mice, but not by preventing DNA damage. Instead, they may stabilize a tumor's ability to grow under oxygen-starved conditions by disrupting a protein called HIF-1.
Researchers found that vitamin E's antioxidant effect is only significant at high doses, exceeding previously used amounts in clinical trials. The optimal dose was determined to be around 1600 IU/day for maximum suppression of oxidative stress.
A Clemson team of chemists has found a new mechanism for antioxidant activity, where antioxidants bind to naturally present iron and copper in the body to prevent DNA damage. This discovery may help treat or prevent illnesses such as cancer, cardiovascular disease, Parkinson's, and Alzheimer's.
Researchers tested vitamins C and E, beta carotene, and their combination in the Women’s Antioxidant Cardiovascular Study. The study found no significant reduction in cardiovascular events or death among participants at high risk for heart disease.
A study reveals that excessive natural antioxidants can lead to reductive stress and heart failure in mice with a specific human mutation. The findings suggest that targeting the antioxidant pathway through a particular enzyme may modify the phenotype of the disease in humans.
Twelve native Australian fruits have been found to be exceptional sources of antioxidants, surpassing blueberries in radical scavenging activities. The study confirms the potential of Australia's native food industry, estimated to be worth $14 million annually, with research aimed at developing new phytochemicals for use in foods.
Research found that birds with brightly colored plumage and those that migrate long distances are more adversely affected by Chernobyl radiation due to their high antioxidant levels. Populations of these species declined significantly, while drab species were less affected.
Researchers at the University of Warwick discovered a glycation process that creates a metabolic memory in diabetes, persisting even after glucose levels are corrected. The study suggests early tight control of glucose and antioxidant use can mitigate complications, but long-term antioxidants may have health problems.
Mercury has been shown to activate phospholipase D enzyme in cells lining blood vessels, causing damage and contributing to vascular disorders. Chelation therapy and antioxidants have been found to suppress this activity, suggesting potential preventive measures against mercury-induced cardiovascular disease.
A recent study evaluated the incidence of malignancy in small pancreatic tumors and identified predictors such as age, gender, symptoms, and radiographic features. The findings suggest that very small tumors with no other symptoms or radiographic indicators have a low risk of malignancy.
Recent research evaluates the progress made to date in diagnosing and treating pancreatic cancer, highlighting promising new applications of technology that will improve survival rates. The studies also identify key predictors of malignancy, including age, gender, symptoms, and radiographic features.
A study found no association between regular multivitamin use and localized prostate cancer, but an increased risk of advanced prostate cancer among men who took high doses or had a family history. Men taking selenium, beta-carotene, or zinc supplements were also at higher risk.
A randomized clinical trial found that a 300-milligram dose of CoQ10 did not improve Parkinson's disease symptoms in patients. However, the treatment was well-tolerated and increased blood levels of CoQ10, suggesting potential benefits at higher doses.
Researchers at Ohio State University found that male mice developed squamous cell carcinoma tumors earlier and had more aggressive tumors than female mice. The study suggests that gender-linked differences in antioxidants may be the key reason behind this disparity.
Researchers found that longer baking times and higher temperatures can increase antioxidant levels in whole wheat pizza dough by up to 82%. Longer fermentation times also boosted antioxidant levels, with some increases reaching 100%.
A new study suggests daily consumption of a Mars Inc. flavanol-rich cocoa drink can improve and sustain blood vessel function, reversing impairments similar to long-term drug therapy with statins. The flavanol-rich cocoa appears to have independent effects on blood vessels, unrelated to antioxidant actions.
Researchers found that flavonoids are poorly absorbed by the body and rapidly metabolized, unlike vitamins C and E. However, they can influence cell signaling pathways and gene expression, potentially preventing cancer and heart disease. A moderate intake of flavonoids from fruits and vegetables may be sufficient.
A meta-analysis of 68 randomized trials found that antioxidant supplements beta carotene, vitamin A, and vitamin E were associated with increased mortality risk. Vitamin C showed no significant association, while selenium use tended to reduce mortality risk.
Researchers found that honeydew honeys have greater antioxidant properties than nectar honeys due to their high polyphenol content and other chemical characteristics. The study suggests that honeydew honeys could be a valuable source of natural antioxidants for health benefits.
A new study suggests that pre-dive intake of antioxidants Vitamin C and E can reduce alterations in cardiovascular function. This intervention showed a positive effect on vascular endothelial function, while other cardiac changes were unaffected.
A study published in the Society of Integrative Oncology's Third International Conference found that antioxidant therapies do not hinder the effectiveness of radiation therapy for prostate cancer. The study, conducted by Cancer Treatment Centers of America, reviewed PSA levels of prostate cancer patients after receiving radiation thera...
Researchers found that synthetic antioxidants significantly reduced pain-like behavior in mice with inflamed hind paws, with 70-90% reduction during acute phase and 78-98% reduction during tonic phase. This suggests that antioxidants may fight chronic pain by helping the body break down free radicals.
Researchers found that dried plums have high antioxidant capacity and can effectively prevent oxidation of fatty acids in meat products like sausages and roast beef. The plum puree can also enhance flavor and reduce laxative concerns when used in moderation.
Researchers at UTMB have developed an antioxidant treatment that reduces oxidative stress and inflammation caused by RSV, a common and dangerous early-childhood infection. The treatment, tested on laboratory mice, also lowers asthma-like symptoms after the virus has been cleared.
A nationwide study aims to slow vision loss from AMD by testing a combination of vitamins, minerals, and fish oil. The study will examine whether the added nutrients can further reduce AMD progression, potentially saving over 300,000 people from vision loss.
Researchers found that female house finches deposit significantly more antioxidants into eggs sired by unattractive males, which protects the embryo during development. This strategic allocation allows females to maximize reproductive output despite potential limitations from suboptimal pairings.
A study found that Pycnogenol heals diabetic leg ulcers by improving blood circulation and reducing tissue necrotization. Patients treated with oral and local Pycnogenol experienced a significant decrease in ulcer size and had higher oxygen presence in the skin.
Researchers found that drinking three or more servings of fruit and vegetable juices per week reduces the risk of developing Alzheimer's disease by 76 percent. The benefit was particularly enhanced for subjects carrying a specific genetic marker linked to late-onset Alzheimer's disease.
Researchers are investigating antioxidants for preventing or treating rickettsia bacteria, a deadly tick-borne illness. The study, funded by the National Institute of Allergy and Infectious Disease, aims to identify novel therapeutic targets for rickettsial diseases.
Scientists at Johns Hopkins have successfully blocked the advance of retinal degeneration in mice with antioxidants, including vitamin E and alpha-lipoic acid. The study found that high oxygen levels in the retina kill cone photoreceptors, which are critical to central vision.
Researchers at Ohio State University found that moderate doses of tocotrienol, a natural form of vitamin E, reach concentrations in human blood plasma sufficient to protect against neurological damage following stroke. The supplement also exhibits non-antioxidant protection against neurodegeneration.
Research on POMx reveals its potent antioxidant properties, offering cardiovascular and disease protection similar to pomegranate juice. The study's findings align with previous research on the Wonderful variety of pomegranate, which has been linked to prostate cancer benefits.
Mushrooms contain high levels of polyphenols and ergothioneine, which contribute to their antioxidant properties. The study found portabella and crimini mushrooms have the highest ORAC values, indicating they are a valuable addition to a varied diet.
Researchers challenge widely accepted opinion on probucol's protective effect against heart disease, revealing that a different part of the molecule is responsible for its benefits. The study also found no relationship between oxidized cholesterol and heart disease severity.
The study found that antioxidant therapy with tempol prevented the onset of high blood pressure, proteinuria, and placental abnormalities, improving birth weight and fetal growth. Tempol treatment also reduced fetal deaths by half and normalized placentas, suggesting a promising approach to treating pre-eclampsia.
Researchers found that gamma-tocopherol, commonly consumed through corn and soybean oil, destroys animal cells by preventing proper protein folding. In contrast, alpha-tocopherol does not have this effect. The study suggests a possible evolutionary explanation for the body's preference for alpha-tocopherol.
The study shows that vitamin C supplements can protect against the loss of vitamin E in smokers, reducing cancer risk. Smokers who took supplements had about the same level of antioxidant protection as non-smokers.
A new way to stimulate the brain to release antioxidants has been discovered by researchers, potentially treating ischemic stroke, multiple sclerosis, and neurodegenerative disorders. The NEPPs compound activates the Keap1/Nrf2 pathway to regulate antioxidant production, offering a promising approach for neuroprotection.
Researchers found that dark chocolate improved arterial flow and reduced platelet activity, benefiting vascular health in smokers. A daily treat of 40g dark chocolate improved smoothness of arterial flow for eight hours.
The red kiwi has been found to have a promising nutritional profile, making it a potential addition to the diet for its high antioxidant content and low calorie count. The fruit's vibrant red color is also attributed to the presence of anthocyanins, which have been linked to several health benefits.
Researchers highlight the importance of antioxidants in fighting off winter ailments. Apples contain more disease-fighting compounds than other varieties, while hot cocoa, chamomile tea, and cranberries may also have health benefits.
Researchers at Penn State developed a new assay to quantify ergothioneine in fungi, finding that white button mushrooms have about 12 times more of the antioxidant than wheat germ and 4 times more than chicken liver. Exotic mushrooms contain up to 40 times as much ergothioneine as wheat germ.
A recent study by the University of Scranton found that coffee provides more antioxidants than any other dietary source in the US. The study analyzed over 100 food items and found that both caffeinated and decaf versions of coffee have similar antioxidant levels, making it the number one source of antioxidants.
Researchers have discovered a novel probucol-analog that effectively protects against atherosclerosis without the same side effects as its predecessor. This breakthrough compound induces an anti-oxidative and anti-inflammatory pathway in blood vessel walls, offering new hope for treating people with or at risk of heart disease.
A team of researchers discovered a gene called Nrf2 that plays a critical role in regulating inflammation and susceptibility to asthma. The findings provide insights into the human body's defense mechanisms against stress and may hold potential for developing new treatments.
Researchers analyzed eight apple varieties and found Red Delicious and Northern Spy apples to have the highest antioxidant levels. Polyphenols in the skin and flesh of these apples were responsible for the highest antioxidant activity, with epicatechin and procyanidin B2 being key contributors.
Chronic inflammation during dialysis enhances oxidative stress, leading to cardiovascular disease, malnutrition, and poor outcomes. Antioxidant supplementation and ROS modulation are proposed solutions to prevent these complications.