Articles tagged with Postdoctoral Work
UT Southwestern researchers discovered how a protein called nicastrin is involved in the production of beta-amyloid, a key suspect in Alzheimer's disease. By targeting just this portion of the enzyme, they hope to create treatments that block the formation of amyloid plaques without affecting other essential functions.
A growing number of older adults suffer from mental disorders, with one-third experiencing a mental disorder at any given time. The University of Rochester Medical Center has received a NIMH Training grant to support postdoctoral researchers in developing skills for independent research.
Researchers at UT Southwestern Medical Center have developed a new gene silencing technique that targets chromosomal DNA to shut down gene expression in cultured cells. By blocking the ability of chromosomal DNA to be copied into RNA and made into proteins, this approach offers a promising strategy for treating and curing disease.
Researchers at UCLA have successfully created a nano valve that can trap and release molecules on demand, controlling them at the nano scale. The device uses switchable rotaxane molecules attached to a tiny piece of glass, allowing for precise control over molecule movement.
Researchers at UT Southwestern Medical Center have identified ephrin-B3 as a molecule that inhibits the regrowth of spinal nerve cells. The study found that ephrin-B3, which normally helps control nerve fiber growth during embryonic development, is also present in high levels in adult myelin and blocks neuron regeneration.
A new study published in the Journal of Immunology reveals that allergic eye disease can significantly increase the risk of corneal transplant rejection. Researchers found that mice with ocular allergies experienced a dramatic increase in graft rejection, with all grafts rejected in affected mice.
Barron and Monteiro-Riviere's project explores fullerene interactions with skin cells, aiming to develop new nano-biohybrid materials. The researchers will investigate physiochemical properties of fullerenes to predict uptake and activity.
Researchers have identified potential brain structures responsible for face recognition in individuals with congenital prosopagnosia. Preliminary findings suggest a genetic basis for the condition, which can have socially debilitating consequences if left undetected.
Research shows that contemporary irrigation projects have diverted river basins, introducing excess fresh water that disrupts mangrove tree species composition and ethnobiological relationships. Early detection of such changes is essential for preventing further mangrove degradation and protecting vital ecosystems.
Molecular messengers Erk-1 and Erk-2 bind to vimentin, protecting their phosphorus message from loss. This linkage enables the safe transmission of the message along the axon, reaching the cell body for healing.
QS-21A has been shown to significantly improve the body's immune response in vaccine therapies against aggressive diseases such as melanoma and HIV-1. By improving its potency, QS-21A could save patients money on expensive vaccines and stretch limited supplies.
Researchers found that when individual insects were removed from their groups, they suffered high mortality rates due to predation. In contrast, group-traveling insects remained relatively safe, suggesting that band formation provides a protective advantage.
Researcher Anne Lincoln found that female Academy Award nominees tend to begin their acting careers at a younger age than male nominees. By analyzing the average age of Oscar nominees from 1928-2001, she discovered historical trends suggesting women start earlier, which may explain the gendered age disparity between winners and nominees.
UGA's Center for Tropical and Emerging Global Diseases has received a grant to train Brazilian scientists in bioinformatics, aiming to combat tropical diseases such as schistosomiasis. The program will support the development of analysis infrastructure and provide opportunities for trainees to work with NIH-funded studies.
Scientists have identified a crucial role of HDAC4 in regulating bone formation, and its disruption can lead to developmental defects. The discovery opens new possibilities for designing drugs to control bone growth and may help prevent osteoporosis.
Researchers at Johns Hopkins University have found a possible link between the strange electrical waves in their hearts and the cause of accelerated heartbeats. They discovered that when implanted cardioverter defibrillators triggered a series of unusual electrical pulses, they sometimes triggered the formation of these same spiral waves.
Researchers at UT Southwestern Medical Center conducted the first comprehensive study on liposuction's physiological impact, analyzing its effects on the heart and lungs, as well as electrolyte changes. The study found that levels of lidocaine and epinephrine must be closely monitored to ensure patient safety.
A study published in Neuron found that the activation of PKG-II enzyme is crucial for the internal clock to signal the completion of nighttime processes and enter the day. Disrupting this enzyme's activity leads to a significant phase delay in circadian rhythm, effectively forcing the clock back in time.
A team of scientists at Scripps Research Institute has discovered a new genetic component of the mammalian clock, known as Rora. This discovery holds promise for understanding circadian rhythms and their role in health and disease, including conditions like jet lag and sleep disorders.
Researchers at UT Southwestern Medical Center have developed a new technique called chromatin array, which provides a detailed picture of gene activation and expansion. This technology allows for the detection of genes that are not accessible using traditional RNA microarrays, enabling scientists to study previously inaccessible genes.
The survey found that salaries have grown by 4% since 2001, with median academic salaries at $76,000 and outside academia at $88,000. Life scientists in universities and self-employment report high job satisfaction rates, while those in pharmaceutical industry receive lower marks.
Researchers at University of Illinois at Urbana-Champaign used strong magnetic fields to alter the electronic structure of carbon nanotubes, converting them from metallic to semiconducting and back. This phenomenon was made possible due to the Aharonov-Bohm effect, which is a fundamental aspect of quantum mechanics.
Researchers at Duke University have discovered signs of superfluid hydrodynamics in a degenerate gas of lithium-6 fermionic atoms. The findings suggest that these atoms can exhibit behavior characteristic of a fermionic superfluid, providing new insights for studying high-temperature superconductivity.
Researchers found that apoE4 produced by neurons is susceptible to fragmentation, leading to increased tau phosphorylation and damaging brain cells. The study suggests targeting a neuron-specific enzyme to prevent Alzheimer's disease progression.
Researchers at UT Southwestern Medical Center found a direct link between excess body weight and the formation of uric acid kidney stones. The study, which tracked nearly 5,000 patients, suggests that weight loss may be an effective therapy for preventing stone formation.
Researchers at UT Southwestern Medical Center have discovered a potentially new avenue for treating human narcolepsy by introducing the brain chemical orexin into genetically engineered mice. The study, which uses knockout mice that lack orexin-producing cells, finds that artificially reintroducing orexin alleviates narcoleptic symptom...
The Emory-AUC FIRST consortium is one of six US programs linking top-ranked minority-serving institutions with research institutions. The program provides training and mentorship for postdoctoral fellows, increasing diversity in academia and industry.
Researchers at University of Illinois at Urbana-Champaign found that combining RU 486 with relaxin could hasten labor and promote healthy delivery in rats. The study suggests that this two-drug approach may also shorten painful labor and reduce Caesarean sections in humans.
Researchers at Purdue University identified a protein on intestinal cells that allows Listeria monocytogenes to attach and cause infection. Understanding this mechanism could help develop a vaccine strategy to prevent the deadly disease, which has a 20% fatality rate.
A study by Ohio State University researchers found that the genes TOC1 and ZTL control a plant's circadian clock. The study revealed a strong physical interaction between these genes, with ZTL degrading TOC1 to regulate the clock's pace. This discovery sheds light on mechanisms controlling plant flowering time and may benefit agriculture.
UT Southwestern Medical Center researchers found that the absence of a key oxygen-sensing molecule can lead to multiple developmental defects. The study created a mouse model lacking this protein, which resulted in cardiac hypertrophy, fatty liver, eye defects, and increased oxidative stress.
The Netherlands Organization for Scientific Research (NWO) has awarded VIDI grants to 79 talented young researchers who have developed innovative scientific research ideas. The successful candidates will receive funding to develop their own research lines, with NWO covering almost 70% of the budget.
A four-year collaborative project aims to predict wildfire behavior using remote-sensing data and computer animation. The model will output a 3D 'movie' predicting fire behavior for the following hour, helping fire managers make informed decisions.
The MIT team has achieved a record-low temperature of 500 picokelvin, six times lower than the previous record of 3 nanokelvin. This breakthrough could lead to vast improvements in precision measurements and new insights into atomic physics.
Researchers found that male baboons give priority care to their own genetically related offspring, despite multiple males mating with the same female. This discovery raises questions about how male baboons recognize and distinguish between their genetic and behavioral offspring.
The American Association for Cancer Research (AACR) accepts applications for several research fellowships to support salary and benefits for postdoctoral and clinical fellows. The deadline is Wednesday, October 15, 2003, and awards are open to researchers worldwide.
Researchers at UT Southwestern Medical Center have identified phosphatidylinositol 4 phosphate (PI4P) as the main regulator of membrane trafficking in the Golgi. This finding debunks a decade-old theory and provides insight into the vital process of cell survival.
A team of scientists has identified a molecule called bourgeonal that activates the human sperm receptor protein, which may play a critical role in fertilization. The discovery could lead to new non-toxic contraceptives and provide valuable insights into chemical communication during fertilization.
SMU and UNC researchers discovered that the E(Z) protein silences genes by modifying a specific chromatin protein, a mechanism found to be conserved in both humans and Drosophila. This breakthrough sheds light on how Polycomb-group proteins regulate gene expression during development.
Researchers at UT Southwestern Medical Center have discovered a protein called Homeodomain-Only Protein (HOP) that regulates heart growth from fetal stage to adulthood. HOP helps control the balance of cardiac cell proliferation and differentiation, with disrupted levels leading to abnormal heart development.
Researchers found that 40% of rejected lungs could have been candidates for transplantation, more than doubling the number of potentially suitable donor lungs. The study highlights the need for a prospective assessment of selection of donors for lung transplantation to potentially save thousands of lives.
Luesch will receive the $45,000 fellowship to investigate new cancer drugs at The Scripps Research Institute. He completed his Ph.D. work this summer at the University of Hawaii at Manoa under Richard E. Moore, Ph.D., and will join Peter G. Schultz, Ph. D.
Dr. Scott, a Columbia University neurobiologist, has won a major career award from the Burroughs Wellcome Foundation for her research on the Drosophila gustatory system. The $500,000 award will support her work over five years, enabling her to investigate how the brain translates sensory stimuli into behavioral responses.
The National Science Foundation is launching four new institutes to bolster mathematical research and education. The institutes will focus on interdisciplinary collaboration and data-driven scientific challenges, with an emphasis on underrepresented groups.
The University of California, Davis, has received a $1.9 million grant to support math graduate students' career development. The VIGRE program will provide fellowships and stipends for undergraduate and graduate students, as well as postdoctoral researchers, to help them secure jobs in the software and computer industries.
Researchers found that a calcium-signaling protein transforms sedentary, easily fatigued muscle fibers into energy-producing, fatigue-resistant type I muscle fibers. This discovery could lead to novel measures to stimulate muscles in patients with chronic diseases or individuals confined to bed rest.
Researchers at Virginia Tech are developing a more reliable and durable wood adhesive, polymeric isocyanate, to enhance the strength and stiffness of wood composites. The new adhesive reduces undesirable swelling caused by moisture and eliminates formaldehyde emissions.
Daniel Crawford's research focuses on studying the structure and properties of large chiral molecules, such as amino acids, to predict experimental data. His proposed work aims to speed up the synthesis of natural products with biological importance.
Researchers at the University of Washington have made significant progress in understanding how hydrogen atoms are transferred between molecules, a key step in creating new compounds. This breakthrough could lead to more efficient manufacturing methods, cleaner product development, and improved chemical reactions.
Kansas State University researchers have created blue micro LEDs that can be used in smaller items like cell phone displays. The new technology increases efficiency by 60 percent compared to conventional LEDs, which can lead to significant energy savings worldwide.
A new study by University of Washington economists found that wives tend to cut back on spending after their husbands retire, indicating a shift in household bargaining power. This difference is attributed to the fact that wives are typically younger and live longer than husbands, leading them to prioritize saving over consumption.
A recent study by Carnegie Mellon University found that attending to a conversation significantly distracts the brain from processing complex visual information. Brain activity decreased by 29% when participants were simultaneously listening to a sentence and doing a complex visual task.
The American Federation for Aging Research (AFAR) has awarded $10 million in new grants to support aging research, primarily focusing on junior faculty members. The grants will enable these investigators to make long-term commitments to the field of aging research.
A clearer picture has been obtained on why the protein doesn't function properly in the milder form of cystic fibrosis, attributed to segments sticking together and interfering with chloride flow. This discovery opens doors for new avenues of research in rational drug design.
A survey conducted by the University of Illinois found that farmers are twice as likely to continue working beyond age 65 compared to people in similar professions. The average age of farmers 65 or older was 73, with a third being 75 years old and having farmed for 46 years.
Researchers at Northwestern University have created a world's smallest and sharpest pen that can draw lines just a few dozen molecules wide, opening up new ways to explore the nano-world of electronics based on molecules. The 'dip-pen nanolithography' technique uses an atomic force microscope to transfer molecules with high precision o...