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Major typhoid fever surveillance study in sub-Saharan Africa indicates need for the introduction of typhoid conjugate vaccines in endemic countries

A new study finds that the high burden of typhoid fever in sub-Saharan African countries calls for stronger prevention strategies, including the use and implementation of typhoid conjugate vaccines. The study estimates that there are 12.5 to 16.3 million cases of typhoid every year with 140,000 deaths.

SourceInternational Vaccine Institute·JournalThe Lancet Global Health·TypeObservational study·DateMar 12, 2024

Study finds no safety concerns when the dapivirine vaginal ring is used during the second and third trimesters of pregnancy, according to results presented at CROI 2024

A new study by the Microbicide Trials Network found no safety concerns with using the dapivirine vaginal ring during all stages of pregnancy. The research provides sufficient evidence that the ring is safe to use throughout pregnancy to protect against HIV, which poses a higher risk than at any other time.

SourceMicrobicide Trials Network·TypeRandomized controlled/clinical trial·DateMar 5, 2024

Study reveals significant discrepancies in common poverty measurement approaches

A new study from Stanford University found significant discrepancies in common poverty measurement approaches, leading to vastly different conclusions about who lives in poverty. The research suggests that the choice of measurement approach can completely change the extent to which programs and policies reach vulnerable populations.

SourceStanford University·JournalProceedings of the National Academy of Sciences·DateFeb 5, 2024

The heat is on: UMass Amherst scientists discover southern Africa’s temps will rise past the rhinos’ tolerance

Rising temperatures caused by climate change will impact southern Africa's remaining black and white rhinoceros populations, scientists report. The region's diverse national parks will struggle to adapt to increasing heat, with some species facing extinction due to rising temperatures and changing precipitation patterns.

SourceUniversity of Massachusetts Amherst·JournalBiodiversity·DateJan 17, 2024

Protected areas for elephants work best if they are connected

A new study published in Science Advances suggests that protected areas for elephants are most effective when connected to allow populations to stabilize naturally. This approach, known as 'connecting parks,' enables herds to move freely and absorb immigrants, reducing the need for human intervention.

SourceDuke University·JournalScience Advances·TypeData/statistical analysis·DateJan 5, 2024

Classifying the natural history of asymptomatic malaria

A recent study in Uganda found that asymptomatic individuals with low-level malaria infections had highly variable parasite dynamics and species present. Frequent sampling every other day or daily was sufficient to detect a proportion of infections similar to daily testing, but less frequent tests may miss up to one-third of cases.

SourceUniversity of Washington School of Medicine/UW Medicine·JournalThe Lancet Microbe·TypeExperimental study·DateJan 4, 2024

New larks revealed in Africa

Researchers at Uppsala University have identified nine distinct evolutionary lines among African lark species, revealing new species diversity. The study proposes splitting two known species into seven, while also confirming convergent evolution and diverging relationships among closely related species.

SourceUppsala University·JournalZoological Journal of the Linnean Society·TypeObservational study·DateDec 20, 2023

Were Neanderthals morning people ?

Genetic material from Neanderthal ancestors may have influenced the preference for waking up early in some people. Studies found that introgressed genetic variants from Neanderthals are associated with increased morningness and a shorter circadian period, which is beneficial at higher latitudes.

SourceOxford University Press USA·JournalGenome Biology and Evolution·TypeContent analysis·DateDec 14, 2023

Rice study: AI provides more accurate analysis of prehistoric and modern animals, painting picture of ancient world

A recent study published in Annals of the New York Academy of Sciences found that AI technology can accurately identify prehistoric and modern African antelopes, with an accuracy rate of over 90% compared to humans. This breakthrough sheds light on ancient ecosystems and their impact on human evolution.

SourceRice University·JournalAnnals of the New York Academy of Sciences·TypeData/statistical analysis·DateDec 14, 2023

“On-demand” HIV prevention method for women being tested in second early phase trial

The TAF/EVG fast-dissolving vaginal insert is being evaluated in a Phase 1 study to determine its safety and user acceptability. The study aims to assess the product's effectiveness as an on-demand HIV prevention method for women, particularly those who do not want or can't use daily PrEP or long-acting products.

Experimental HIV vaccine regimens likely to be ineffective in preventing HIV acquisition, PrEPVacc study reports

A new HIV prevention study, PrEPVacc, has stopped further vaccinations due to little or no chance of demonstrating vaccine efficacy in preventing HIV acquisition. The trial, testing two different combinations of HIV vaccines and a new oral PrEP drug formulation, aims to find out if either can prevent HIV infection.

SourcePrEPVacc·TypeRandomized controlled/clinical trial·DateDec 6, 2023

Trump-era policy on global aid curtailed family planning services in Africa

A new study found that the Protecting Life in Global Health Assistance policy reduced provision and use of contraceptives, as well as community health volunteer services, in African countries. This policy, formerly known as the Mexico City Policy, had detrimental effects on family planning service delivery and utilization.

SourceBoston University School of Public Health·JournalScience Advances·TypeSurvey·DateDec 6, 2023

Colorectal cancer in sub-Saharan Africa: Lack of basic care is costing lives

A new study found that most people with colorectal cancer in sub-Saharan Africa receive inadequate treatment, leading to significantly improved life expectancy through simple measures. The mortality rate is up to 3.5 times higher in regions studied compared to countries with medium HDI scores.

SourceMartin-Luther-Universität Halle-Wittenberg·JournalJournal of the National Comprehensive Cancer Network·TypeObservational study·DateNov 22, 2023

7 in 8 homicide victims in South Africa are male

In a study of almost 20,000 post-mortem investigations, researchers found that 7 in 8 homicide victims in South Africa were male. Homicide rates peak on weekends and holidays, highlighting the need for targeted interventions to address this epidemic.

SourcePLOS·JournalPLOS Global Public Health·DateNov 22, 2023

Potential therapeutic target found to combat tuberculosis, a disrupted NAD(H) homeostasis

A recent study published in Nature Communications reveals that disrupted NAD(H) homeostasis is a key factor in tuberculosis pathogenesis. The researchers found that the glycolytic pathway can be selectively inhibited using an LDH enzyme with mostly LDHA subunits, which preferentially converts pyruvate to lactate and NADH to NAD+.

SourceUniversity of Alabama at Birmingham·JournalNature Communications·TypeExperimental study·DateNov 20, 2023

Warming world, widening gap: climate change’s toll on poverty and inequality in South Africa

A new study reveals that climate change widens the inequality gap in South Africa, particularly for poorer segments of the population. The research highlights the need for climate change policies to address poverty and inequality, as warming is expected to reduce average growth and exacerbate inequalities by the end of the century.

SourceCMCC Foundation - Euro-Mediterranean Center on Climate Change·JournalEnvironmental Research Letters·DateNov 2, 2023

The role of supply chain in knowledge transfer: a case study of South African automotive industry

A recent study analyzed the South African automotive industry to understand the link between multinational vehicle assemblers and local parts suppliers. The research team found that while production of first-tier suppliers increased with automobile expansion, lower-tier suppliers showed no similar growth. This suggests a diamond-shaped...

SourceSophia University·JournalWorld Economy·TypeData/statistical analysis·DateOct 19, 2023

Endemic malaria found in high, dry northwestern Kenya

A new study by Duke University researchers has found endemic malaria in Turkana County, Kenya, with a significant incidence of Plasmodium vivax, a parasite historically rare in sub-Saharan Africa. The presence of invasive mosquito species Anopheles stephensi also poses challenges to the continent's malaria control efforts.

SourceDuke University·JournalEmerging Infectious Diseases·TypeObservational study·DateOct 12, 2023

Researchers show consequences of inaction on devastating banana disease

Banana Xanthomonas Wilt (BXW) could cause a 55% reduction in banana production in newly affected regions within 10 years. The disease is projected to result in significant economic losses, with consumers bearing 40% of the estimated $25 billion cost.

SourceThe Alliance of Bioversity International and the International Center for Tropical Agriculture·JournalFrontiers in Sustainable Food Systems·TypeComputational simulation/modeling·DateOct 9, 2023

Integrated health services in Africa can improve patient care and save money

A new study led by UCL researchers finds that integrated health care for chronic high-burden conditions like diabetes and hypertension is feasible and cost-effective. The study showed that integrated care was associated with high levels of retention in care, no adverse effect on viral suppression among people with HIV, and cost-saving ...

SourceUniversity College London·JournalThe Lancet·TypeRandomized controlled/clinical trial·DateOct 6, 2023