Articles tagged with Discovery Research
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
A new study has discovered how antibodies help protect against Strep A infections and is contributing to the development of a Strep A vaccine. The research used the world's only human challenge model for Strep A, which uncovered the power and potential for this model to accelerate vaccine development.
A new brain-mapping technique identified memory-related brain cells vulnerable to protein buildup, a key factor in Alzheimer's disease. The study found that certain cell types in the hippocampus and cortex were more affected by tau buildup.
Researchers at the University of Texas at Austin have developed sapphire-based nanostructures with self-cleaning capabilities, repelling fog, dust, and glare. These nanostructures maintain a high level of durability and performance while being mechanically robust and multifunctional.
The Einstein Probe mission aims to probe X-ray transient sources and explosive astrophysical phenomena, contributing significantly to astronomical research. The mission's sophisticated observational instruments will enhance the detection of sudden X-ray transients and monitor variability in known celestial sources.
A new study found that even when women receive similar amounts of recognition from peers as men for excelling in physics classes, they perceive significantly less peer recognition. The researchers discovered that men report higher perceptions of peer recognition than women in both lab and lecture courses.
SLAC researchers develop a laser-based shaping technique to compress billions of electrons into a length less than one micrometer, producing an electron beam with femtosecond-duration and petawatt peak power. This achievement opens up new discoveries in quantum chemistry, astrophysics, and material science.
The new AI model leverages hypergraphs to quickly and accurately identify therapeutic gene targets for diseases. HIT outperformed existing models in all tested metrics, demonstrating its accuracy in classifying therapeutic gene targets with great precision.
A research team at the University of Limerick has developed a groundbreaking method to produce carbon fibre while reducing its energy footprint by up to 70%. The CARBOWAVE project uses plasma and microwave heating technologies to make carbon fibre more efficient and cost-effective.
Researchers have developed a new technique for quantum sensing using nanodiamonds in microdroplets, which can detect trace amounts of certain ions and molecules. This method uses flowing droplets and carefully modulated microwaves to ignore unwanted background noise and add precision.
A study published in Aging (Aging-US) found associations between several environmental exposures and epigenetic aging in a large sample of US adults. Cadmium, lead, and cotinine were linked to faster biological aging, increasing the risk of age-related diseases such as heart disease and cancer.
New research reveals that exoplanets with masses similar to Jupiter formed much sooner than previously thought, suggesting the accretion process takes place early. This finding could lead scientists to re-evaluate and revamp their theories of planet formation for the solar system and elsewhere.
The Aligning Science Across Parkinson’s (ASAP) initiative offers funding of up to $6M for research community members to develop sustainable tools for Parkinson’s disease research. The funding supports the development of preclinical models, detection reagents, and modulation agents to accelerate therapeutic research.
Core-shell nanoparticles offer effective drug encapsulation, shielding from degradation, and controlled release. This innovation enables targeted drug delivery, improving treatment outcomes and reducing side effects. The versatility of these nanoparticles allows for tailored materials to suit different therapeutic needs.
Researchers at USC Stem Cell discovered a gene called KCTD20 that suppresses glutamate toxicity, leading to enhanced tau protein clearance. This approach offers a promising therapeutic strategy for patients with tau-related neurodegenerative diseases, including Alzheimer's disease.
Researchers create microfluidic device to sort tumor cells based on adhesive strength, revealing potential method to predict aggressive cancer behavior. The study's findings offer a promising approach for personalizing treatment plans and identifying high-risk patients.
Researchers found that aspirin prevents cancers from spreading by decreasing a clotting factor called thromboxane A2 and releasing T cells from suppression. This discovery could lead to the development of targeted treatments to prevent cancer metastasis, making aspirin potentially less expensive than antibody-based therapies.
Researchers at the University of Missouri have identified a small molecule drug that targets a specific serotonin receptor, showing promise as a treatment for sarcopenia. The study suggests that this neurotherapeutic can improve muscle strength by activating motor neurons to fire more effectively.
Researchers at Johns Hopkins University have discovered genes that control fruit size in tomatoes and eggplants, opening up opportunities for new varieties and improved agriculture. The study could lead to the development of larger, more nutritious fruits, and has significant potential for global food security.
The Whole Health Consortium at Virginia Tech has funded several research projects, including one that uses geospatial analysis to improve healthcare access for veterans. Another project aims to develop a 'just-in-time' intervention for chronic pain and opioid use disorder in Appalachia.
Researchers discovered 27 standardized bone tools over 1.5 million years old in Tanzania's Olduvai Gorge, pushing back known standardization by 500,000 years. The discovery suggests an early ability for planning and knowledge transmission among ancient populations.
The Damon Runyon Cancer Research Foundation has named 13 new Fellows, awarding them $300,000 each to investigate cancer causes and mechanisms. Five recipients of the Dale F. Frey Award for Breakthrough Scientists will also receive an additional $100,000 investment to catapult their research careers.
Researchers developed a nanoparticle that delivers an mRNA vaccine targeting a KRAS antigen, boosting the immune response against pancreatic cancer. Experiments in mice showed inhibited and prevented tumor growth, as well as long-term protection against recurrence.
Researchers discovered that females' dormant X chromosome reactivates in late life, expressing genes related to brain development and cognitive health. This phenomenon may explain why women outlive men and retain their cognitive abilities longer.
Researchers at USC Dornsife College of Letters, Arts and Sciences have made a breakthrough discovery about how tiny protein clusters form in cells. These nanoclusters play a crucial role in mechanotransduction, a process that fails in people with Emery-Dreifuss muscular dystrophy, leading to muscle weakness and heart problems.
Pacific children are not meeting daily recommended intakes for key micronutrients, leading to associations with childhood obesity and acanthosis nigricans. The study highlights excessive sodium intake across the region, posing cardiovascular health risks.
Researchers have discovered alarming levels of microplastics in human brain tissue, with concentrations 3-5 times higher in individuals with dementia diagnoses. The study highlights the need for large-scale human studies to determine dose-response relationships between microplastic exposure and chronic health outcomes.
Dr. Nicholas Fabiano's research reveals exercise reduces suicide attempts but shows no connection to thoughts of suicide or deaths by suicide. His work proposes a paradigm shift in mental health treatment, suggesting exercise as a first-line treatment for depression.
Dr. Melissa Perreault's research combines cutting-edge science with Indigenous knowledge, pioneering sex-specific biomarkers, neuroethics, and psychedelics research in neuropsychiatry. Her work aims to promote inclusive methodologies that consider diverse worldviews and cultural understandings of health.
Children who frequently miss school due to abdominal complaints are more likely to have gut-brain axis disorders like IBS, which can be missed by medical tests. The study found that frequent absences were nearly five times more likely to be caused by functional GI disorders than specific illnesses.
The award honors outstanding research achievements in biological sciences, recognizing diversity and originality in thesis topics. The recipients represent national and international research institutions, including Harvard University and Massachusetts Institute of Technology.
The University of Texas at Arlington (UTA) has earned the prestigious R1 designation, recognizing its highest level of research activity. UTA has maintained this classification since 2015 and continues to demonstrate its commitment to innovation and academic excellence.
A team of researchers has found a stable trio of icy space rocks in the Kuiper Belt using data from NASA's Hubble Space Telescope and the W. M. Keck Observatory. The Altjira system suggests that similar triples may exist, supporting a theory of solar system formation and the formation of Kuiper Belt objects.
A recent study in Nature Communications reveals that white blood cells employ a novel mechanism to dislodge bacteria from human tissues using brute force and integrin-based adhesion rings. The research, led by Xuefeng Wang, has significant implications for understanding the role of macrophages in cleaning up environmental pollutants.
The European Genome-phenome Archive has released the largest ever DNA sequencing dataset on UK child development studies, containing high-resolution data from over 37,000 children and parents. This comprehensive resource can be used to investigate genetic variation's impact on neurodevelopmental conditions and childhood obesity.
Researchers have discovered a novel approach to protecting insulin-producing beta cells from glucolipotoxicity, a condition linked to type 2 diabetes progression. The findings could lead to promising treatments targeting beta cell dysfunction, potentially slowing or preventing disease progression.
TruDiagnostic presents its latest advancements in epigenetic testing, leveraging DNA methylation to predict disease risk. The company has developed over 1,700 Epigenetic Biomarker Proxies (EBPs), outperforming traditional biomarkers in accuracy and effectiveness.
A study published in Biological Psychiatry found that anxiety and apathy lead to different patterns in how people process uncertainty and make decisions. Participants made choices between exploring new options or sticking with familiar ones, revealing distinct computational mechanisms underlying these behaviors.
Researchers found that limiting daytime sleep and getting approximately seven hours of sleep each night in the first week after a concussion may speed up recovery. Youth who sleep more or less than ideal amounts during this period may experience slower symptom resolution.
Researchers at UC San Diego create computational approach to model chiral helimagnets using quantum mechanics calculations. They successfully predicted key parameters, including helix wavevector, period, and critical magnetic field, opening opportunities for designing better materials.
The Magellan Adaptive Optics Xtreme (MagAO-X) instrument observed two young planets orbiting PDS 70, revealing compact rings of dust and startling changes in brightness. The team believes these features are telltale signs of the planet's turbulent youth.
The University of Oklahoma Health Sciences has achieved its highest ever ranking in National Institutes of Health funding, improving its ranking to 102 out of 2,838 institutions and receiving $75.2 million in funding. The college's faculty members conduct numerous types of research across various academic departments.
A Yale-led research team has discovered how a naturally occurring biological mechanism prevents sperm cells from interacting with an egg, preventing fertilization. The study found that OBF13, a sperm antibody, can recognize IZUMO1 on the surface of sperm cells and disrupt fertilization.
A study from the University of Missouri found that rural first-time moms are more likely to stop breastfeeding due to a lack of practical knowledge, community support, and access to lactation consultants. The research aims to improve support and resources for new mothers in rural areas.
The collaboration combines Insilico's Pharma.AI platform with Tenacia's expertise in CNS biology and clinical development. By leveraging generative AI, the partnership seeks to expand therapeutic options and enhance outcomes for patients worldwide. Recent successes by Insilico include the nomination of ISM8969, a BBB penetrable NLRP3 i...
A recent study from the University of Gothenburg found that dental implants continue to function well after nearly forty years. The implants, developed by Professor Per-Ingvar Brånemark, have been shown to remain stable and integrate with bone over an extended period.
Researchers from UC San Diego will present cutting-edge solutions to address global challenges such as climate change and human longevity. The event features a film premiere and thought-provoking presentations on topics like capturing carbon and democratizing health data.
BaCell 3D conference to feature original research in organoids and regenerative medicine, published in Stem Cell Reports. The International Society for Stem Cell Research (ISSCR) partners with Stem Cell Reports to promote discoveries with potential to transform regenerative medicine.
Researchers have identified a new starting point for therapy by targeting SSAT enzyme in psoriasis, restoring regulatory T cell function and breaking inflammation cycle. This approach could lead to a promising alternative treatment option with fewer side effects.
Gustavsson's five-year grant aims to develop innovative tools for visualizing and analyzing DNA organization and interactions in real-time. Her project seeks to uncover the relationship between DNA structure and gene activity, with potential applications in treating diseases linked to gene regulation disruptions.
A study uncovered new genetic clues explaining why some prostate cancers grow slowly while others become life-threatening, identifying 223 mutations that determine tumor progression. The research shows germline and somatic variability work together to initiate and drive prostate cancer.
Researchers capture narwhals using their tusks to investigate, manipulate and influence the behavior of Arctic char fish. The study reveals first evidence of likely play, social learning and personality differences among individual narwhal.
Research finds over 25% of Egyptian milk and dairy products contain E. coli, with one strain causing a Japanese school outbreak; experts hope for effective treatment and prevention methods.
Scientists have identified key corneal neurons involved in sensitivity and developed an experimental model to study nerve regeneration. The Ocular Neurobiology laboratory is participating in the RESTORE VISION project, which aims to improve eye health and quality of life for those affected by rare eye diseases.
Scientists have identified a new target to prevent cold sores by understanding how the herpes virus triggers its own immune response. The discovery has important implications for genital herpes caused by the same virus, with potential treatments in development.
Copper-incorporated microvesicles promote healing, reduce inflammation, and enhance cell growth, offering a multifaceted solution for addressing dental diseases. The technology has vast implications for various fields of medicine, including wound healing and regenerative therapies.
Researchers found a previously unknown mechanism for how aggressive brain cancers reprogram immune system cells. By inhibiting glucose metabolism and lactate accumulation, they eliminated the neutrophils' ability to suppress immune responses.
Researchers have discovered a way to trap iodine in perovskite solar cells using alumina nanoparticles, enhancing lifespan and stability. The modified solar cells maintained high performance for over two months under extreme conditions.
Researchers at Nagoya University have developed a method of artificial photosynthesis that uses sunlight and water to produce energy and valuable organic compounds from waste organic compounds. The technique, called APOS, represents a significant step toward sustainable energy and chemical production.
Researchers developed Janus-type supramolecules that form stable ribbon-type assemblies, guiding the arrangement of ion channels across lipid membranes. The supramolecular channels mediate efficient and selective K+ transport, disrupting cancer cell balance and inducing apoptosis.
Researchers at Nagoya University developed a new technique to improve electrode performance in seawater purification, allowing for higher surface area and increased efficiency. The oxygen-doped electrodes show promise for reducing water purification costs and expanding applications beyond water treatment.