News on early, curiosity-driven science that opens new directions. Covers materials discovery, AI-guided research, pediatric research standards, and energy science.
Researchers at Karolinska Institutet discovered a fundamental mechanism linking breathing to pupil size, which affects vision. The study shows that the pupil is smallest during inhalation and largest during exhalation, impacting visual perception.
Researchers synthesized Fe1+xSe2 nanoflakes with controlled intercalation ratios, discovering a new class of materials with room-temperature magnetism and unique half-metallic behavior. Interkalation regulates magnetic and electrical properties, including Curie temperatures and spin gap.
The University of Texas at Arlington is joining forces with the Texas A&M Engineering Experiment Station to operate a new biomanufacturing center. This partnership will expand UTA's capabilities and provide access to financial support and industry partners, enabling researchers to develop and commercialize production of new bioprod...
Researchers from NUS have pioneered a new catalytic transformation that converts epoxides into fluorinated oxetanes, a coveted class of drug molecules. The discovery potentially opens the door to new medicines and offers a reliable route to incorporate these motifs into the design of novel small-molecule therapeutics.
The five-year grant will aid researchers in understanding the underlying biology of several diseases by studying mitophagy, a process that degrades damaged mitochondria. By examining how genetic modifications affect mitophagy, researchers may discover new methods to address conditions like Parkinson's disease and diabetes.
The collaboration aims to accelerate antibody discovery and development using Harbour BioMed's technology platform and Insilico's AI expertise. The companies will develop next-generation AI-powered antibodies for immunology, oncology, and neuroscience, aiming to deliver innovative therapies with enhanced specificity, efficacy, and safety.
A new study from Western New England University reveals that long-term grape consumption significantly impacts muscle health, with notable benefits for both men and women. Grapes modify gene expression in muscle, potentially offering a new approach to muscle maintenance.
A team of experts has identified six key research priority areas to deliver a fundamental understanding of appendiceal tumors. The study aims to improve disease detection, diagnosis, treatments, and outcomes for patients with this rare cancer, which affects an estimated 3,000 new patients each year.
Researchers at Memorial Sloan Kettering Cancer Center and Weill Cornell Medicine have discovered a vulnerability in the hepatitis B virus that could lead to new treatments. The study found a compound already in clinical trials against cancer that successfully disrupted the virus's ability to infect human liver cells.
A groundbreaking study using AI-driven robotics laboratory identifies Rentosertib, a potent TNIK inhibitor, as a highly effective senomorphic agent capable of reducing aging-related markers. The study reveals TNIK inhibition alleviates key signaling pathways implicated in senescence and fibrosis.
Dr. Gordon Keller's groundbreaking research on directed differentiation of human pluripotent stem cells has illuminated the path to transforming human health. His lab's world-first discovery and pioneering efforts have pushed the boundaries of what is possible, offering hope for regenerating heart, liver, and blood cells.
Dr. Paola Arlotta's groundbreaking research on stem cell-derived brain organoids has redefined human brain development and neurological disease understanding. Her work provides access to the complexities of developing human brains, making her a deserving recipient of the ISSCR Momentum Award.
Researchers discovered noncoding cryptic peptides as an alternative source of target antigens for ovarian cancer. The findings could improve treatment approaches by mobilizing the immune system to attack tumor cells.
Dr. Yonatan Stelzer has made significant contributions to understanding epigenetic mechanisms and embryonic development, challenging conventional knowledge with innovative approaches. His research aims to establish fully data-driven quantitative models of spatiotemporal processes in mammals.
Sylvester's Firefighter Cancer Initiative reduces cancer risk among firefighters and community members by addressing electric vehicle fires. A new gene-editing study aims to treat mitochondrial diseases, while a program connects patients with pathologists to improve understanding of complex results.
Researchers at U of T discover a ginger compound called furanodienone that selectively binds to and regulates nuclear receptor PXR, reducing inflammation in the colon. FDN has been shown to increase tight junction proteins, repairing damage to the gut lining caused by inflammation.
Researchers discovered a novel mechanism of intercellular communication through mRNA transfer between stem cells, allowing for biologically significant effects such as cell fate conversion and pluripotent state maintenance.
A recent MSU study highlights the challenges of diagnosing episodic disabilities like epilepsy, where symptoms fluctuate and can be unpredictable. The research found that 52% of participants experienced delayed diagnoses, while others faced quick confirmations within days of their first seizure.
Researchers at Sainsbury Wellcome Centre develop novel experimental setup called Translocator, isolating fundamental elements of locomotion and motion-source separation. The team finds that individual cells in primary visual cortex use motor and vestibular signals to determine visual flow origin.
A new plant species, Nasa katjae, has been discovered in Peru's Andean cloud forests through citizen science efforts. The species is characterized by its scarlet-red flowers and is potentially vulnerable due to habitat loss and climate change. The discovery emphasizes the importance of protecting remaining pristine habitats.
Researchers at UCSF have identified unique, cancer-specific proteins created through mistakes in RNA splicing. These antigens could be used to create potent immunotherapies that recognize and attack hard-to-treat tumors. The discovery offers new hope for glioma patients and expands the number of targets available for cancer therapy.
A new study reveals that asymptomatic neonatal HSV infections in mice can lead to persistent CNS infection and long-term cognitive decline. Maternal vaccination may prevent this cognitive impairment, suggesting a potential strategy for reducing neurological damage in infected offspring.
UTA research projects contributed $59 million to the national economy in 2024, supporting student development and collaboration with other research organizations. The university's research infrastructure, including cutting-edge equipment, helped drive economic impact in North Texas and beyond.
A new study by Connecticut College reveals that palm trees once thrived in subarctic Canada during the late early Eocene, approximately 48 million years ago. This finding indicates a warmer climate with ice-free winters, unlike previous assumptions.
The University of Texas MD Anderson Cancer Center received nearly $23 million in CPRIT funding to advance cancer research, translational science, and clinical trials. The funding will support the recruitment of a first-time tenure-track faculty member and enhance the understanding of cancer biology.
Assistant Professor Tova Holmes at University of Tennessee Knoxville received a $75,000 Sloan Research Fellowship for her work on searching for new fundamental particles using colliders in high-energy particle physics research.
Researchers at University of Hawaii at Manoa have discovered 10 new marine sponge species in Kāneʻohe Bay, expanding our understanding of sponge biodiversity in the Hawaiian archipelago. The discovery sheds light on the crucial role sponges play in regulating and sustaining coral reef ecosystems.
The Childhood Obesity Prevention, Evaluation and Treatment Toolkit provides healthcare providers with practical guidance for preventing, evaluating, and treating childhood obesity. The toolkit is grounded in scientific evidence and offers actionable treatment approaches for children and adolescents dealing with overweight and obesity.
Researchers have identified a new variant, clade 1b, of the mpox virus that has become more infectious and is spreading rapidly across borders. The study found that this variant primarily spreads through heterosexual contact in densely populated areas, with an estimated fatality rate of 3.4%.
Researchers at Virginia Tech have developed a method to convert gut bacteria into mini protein factories that produce and release sustained flows of targeted proteins within the lower intestine. This approach eliminates a major roadblock in delivering drugs to this part of the body, offering potential treatment for chronic diseases.
Five NYU faculty members have been awarded Sloan Foundation fellowships for their research in inflation dynamics, antibiotics, molecular assembly, geometric interactions, and robotics. The fellowship recognizes exceptional researchers making significant contributions to their fields.
Researchers at Worcester Polytechnic Institute are developing a lightweight, flexible robotic arm that enables wheelchair users to safely grasp and carry objects out of reach. The project builds on origami-inspired designs and novel fabrication methods for modules made of lightweight plastics, 3D printed components, and sensors.
Dr. Sunil Sharma, a renowned expert in creating anti-cancer drugs, has been named director of HonorHealth Research Institute's new Center for Translational Science. He will lead the development of grants, education, and collaborations to translate basic scientific discoveries into advanced treatments.
Researchers created a computational method to track brain cell development over time, capturing unlabeled cells and fine structures in live cultures. The algorithm achieved high precision rates for detecting individual neurons, paving the way for studying neurological diseases and developing therapies.
Researchers found that eBay sellers who respond slowly to buyer offers may be signaling they are close to accepting the price. Buyers, on the other hand, are discouraged by slow responses and less likely to make counteroffers. By taking a slow response as a positive sign, buyers can potentially get better deals.
Researchers have successfully modeled a treatment-resistant form of asthma in mice, shedding light on the role of CD4+T resident memory cells and MHC-II molecules in lung inflammation. The study's findings may lead to new treatments for this severe and debilitating condition.
Researchers at NC State University have developed a new technique to tune the optical properties of quantum dots using light, reducing energy consumption and environmental impact. This method allows for precise control over the bandgap, enabling the creation of high-quality perovskite quantum dots for optoelectronic devices.
Researchers at Gladstone Institutes developed a drug called HypoxyStat that mimics the effects of breathing low oxygen, extending lifespan by over three times in mice with Leigh Syndrome. The drug reversed brain damage, muscle weakness, and other symptoms of the disease, even when given late in life.
A nearly complete skull of the ancient apex carnivore Bastetodon has been discovered in the Egyptian desert, revealing a new species of hyaenodonta. The discovery sheds light on the evolution of hyaenodonts and their global distribution, with findings suggesting they spread from Africa to Asia, Europe, India, and North America.
Researchers unveil Ba-Si orthosilicate oxynitride-hydride as a transition metal-free catalyst, offering a more sustainable approach to ammonia production. The novel catalyst demonstrates exceptional stability and higher activity than conventional ruthenium-loaded MgO catalysts.
Research by West Virginia University expert Kylie Vo found that consumers who believe in karma are more likely to forgive companies that behave immorally and less likely to boycott them. In contrast, non-moral transgressions like defective products or misleading claims can severely damage consumer-brand relationships and brand value.
A Connecticut College professor has been awarded a $204,499 NSF grant to consolidate his research on protists, integrating decades of data to better understand their role in aquatic ecosystems and climate change. The project aims to provide critical insights into nutrient cycling, ecosystem stability, and species migration over geologi...
Researchers found that a rare genetic syndrome causes different damage mechanisms in male and female brains, affecting neurogenesis and energy production. The study suggests that the ADNP protein plays a crucial role in brain development and aging, with distinct functions in males and females.
Researchers found a remarkable X-ray flash in archived Chandra Observatory data, hinting at possible explanations: X-ray burst, magnetar flare, or new cosmic event. The discovery showcases the potential of AI for scientific breakthroughs in astronomical archives.
A team of researchers from the University of Arizona College of Medicine – Tucson found that an FDA-approved osteoporosis treatment, risedronate, can correct a gene mutation and normalize heart function in animal models. The study provides hope for treating other rare diseases using precision treatments tailored to individual mutations.
Researchers at DGIST have developed high-capacity, high-safety anode materials that can significantly increase the driving range of electric vehicles. By setting a high initial activation charging voltage, they prevented nano-cracks and structural collapse, leading to improved battery performance and safety.
Researchers at Salk Institute discover SSRIs like Prozac regulate immune response, preventing sepsis in mice. The findings suggest a potential new use for the popular drug, which could lead to life-saving treatments and enhanced global preparedness for pandemics.
The release of a unique Type Ia Supernovae dataset has significant implications for cosmologists measuring the universe's expansion history. The dataset, comprising 3628 supernovae, provides unprecedented precision and accuracy in exploring the properties of these events.
Researchers have identified changes in brain rhythms that indicate seizure activity in Alzheimer's patients. High-frequency oscillations (HFOs) occur at rates two to three times higher in Alzheimer's patients than in cognitively normal individuals.
A study by Durham University has shown that E-coli bacteria produce an enzyme breaking down nutrients from dead cells, offering a banquet for neighboring cells. This process demonstrates that death is not the end of programmed biological processes, which can evolve to function after death.
University of Texas at Dallas researchers have discovered why LiNiO2 batteries break down during charging and are testing a solution to remove the key barrier to widespread use. They developed a theoretical solution that reinforces the material by adding a positively charged ion, creating pillars to strengthen the cathode.
A new treatment, datopotamab deruxtecan, has been approved by the FDA for people with metastatic ER-positive breast cancer. Researchers at Memorial Sloan Kettering Cancer Center have also discovered a new strategy to overcome resistance in prostate cancers, suggesting that targeting mTOR may restore sensitivity. Additionally, an MSK re...
Florida Atlantic University (FAU) has been designated as an R1 institution by the Carnegie Classification of Institutions of Higher Education, recognizing its high research spending and doctorate production. FAU's strong research program fosters interdisciplinary collaboration and drives innovation in various fields.
A Danish study reveals that testosterone treatment can nearly halve the mortality rate among men with Klinefelter syndrome, reducing cardiovascular disease risk and increasing life expectancy. The treatment also improves quality of life and may have positive effects on metabolism, muscle mass, and bone health.
Researchers found a biomarker, RNA Polymerase II (RNAPII), associated with tumor aggressiveness and recurrence in meningioma and breast cancers. The study developed a novel profiling technology, Cleavage Under Targeted Accessible Chromatin (CUTAC), to measure gene transcription activity from DNA, which predicted cancer outcomes.
A University of Nebraska-Lincoln research team has identified methanogens that can consume hydrogen and dissolve calcium carbonate, producing methane. This discovery has implications for the sustainable development of bioenergy sources and challenges current understanding of carbonate mineral stability.
A team of geneticists discovered a gene 'silencer' in junk DNA that prevents the devastating neurological disease autosomal dominant leukodystrophy (ADLD). The silencer element regulates lamin B1 expression, only affecting one type of cell, and its presence can spare patients from fatal symptoms.
Researchers discovered a link between neuroactive steroids in pregnant women's blood and the risk of developing postpartum depression. Measuring these molecules via a blood test could enable doctors to provide treatment sooner. The study may lead to a preventive treatment using existing prescription drugs.
Researchers at the University of Surrey discovered evidence of opposing arrows of time emerging from quantum systems. The study suggests that time's arrow may not be fixed, and instead could flow in both forward and backward directions due to processes taking place at the quantum level.
A team of scientists has uncovered the role of mitochondrial proteins in driving autophagy, a process crucial for maintaining cellular balance and energy production. By regulating this process, researchers hope to develop new strategies for treating metabolic diseases such as obesity and diabetes.