Research on health and aging in later life. Covers attention and cognition, longevity, organ aging, and age-related disease.
A comprehensive atlas of ageing human muscle reveals genetic and cellular processes behind muscle deterioration, including new cell populations that may explain age-related differences. The study also identifies compensatory mechanisms to counteract ageing, offering avenues for future therapies.
A new study found that nasal cells from children respond quickly to SARS-CoV-2 by increasing interferon, restricting viral replication. In contrast, nasal cells from elderly individuals produce more infectious virus particles and experience increased cell shedding and damage.
A noninvasive brain stimulation treatment, transcranial direct current stimulation (tDCS), improved depression and anxiety symptoms among older adults. The treatment benefits persisted at a one-year follow-up, particularly among those with moderate to severe state anxiety.
A new national poll finds that 60% of people aged 50-80 have visited urgent care clinics or retail clinics for medical care in the past two years. Many sought immediate attention, vaccinations, or tests, and 75% plan to use these sites again in the next two years.
The COVID-19 pandemic highlighted the need for high-quality dementia care in nursing homes, where residents face social isolation and staff challenges. Experts emphasize person-centered care, resident involvement, and community connections to improve outcomes.
A new study found that survival rates after hip or spine fractures are comparable to or worse than those seen in patients with certain types of cancer. The study, which analyzed data from over 100,000 Canadians aged 65 and older, highlights the urgent need for secondary prevention interventions before hospital discharge.
A study by Michigan Medicine found that about 1% of older adults using traditional Medicare have used asynchronous patient portal messaging to prompt a bill from their doctor or other healthcare provider. Most e-visits were with primary care providers, mainly for managing high blood pressure and diabetes.
A new EU study has found that over-60s are six times more likely to acquire pneumonia-causing bacteria Streptococcus pneumoniae after daily contact with young children. Pneumococcal infections mainly affect children under two and the elderly, claiming almost two million lives worldwide every year.
Researchers from China conducted a nationwide study to assess optimal treatment strategies for CSDH. The study found that multimodality management and personalized treatment plans significantly reduced recurrence rates.
Long-term treatment with methylene blue (MB) and mitoquinone (MitoQ) did not alter age-related bone loss in mice. Antioxidant interventions are insufficient to inhibit skeletal aging, suggesting alternative approaches may be needed.
A study of 9,740 surveillance colonoscopies found rare colorectal cancer detection and higher advanced neoplasia yields among those with prior advanced adenoma. These findings inform decision-making on continued screening in older adults with a history of colorectal adenomas.
Research suggests that for individuals under 65, maintaining a normal BMI is advisable, while those over 65 may benefit from moderate overweight. This study found a U-shaped relationship between BMI and cardiovascular death risk, with optimal BMI cut-off points varying by age group.
Researchers discovered that mature oligodendrocytes, critical for brain function, can survive for up to 45 days after a fatal trauma, defying the classical programmed cell-death pathway. This finding opens new avenues for understanding and potentially preventing damage caused by aging and neurodegenerative diseases.
Older people with HIV are more likely to have comorbidities and become frail compared to their age groups without HIV. By 65 years old, around 70% of those living with HIV for 20 years or more are living with multiple conditions.
The incidence of STIs among older adults is rising globally, with data from the US CDC showing a more than doubling of rates over the past decade. Experts say misconceptions about age and sex, as well as limited access to sexual health services, contribute to the problem.
A Bar-Ilan University study found that older adult Israelis showed remarkable resilience during the conflict, with lower rates of acute stress and PTSD symptoms compared to younger adults. The study suggests that life experience, emotional regulation capabilities, and coping mechanisms played a significant role in this resilience.
A study of 17,000 hospitalized adults found that inappropriate pneumonia diagnoses were common among older adults and those with dementia or altered mental status. Full-course antibiotic treatment for these patients may be detrimental to their health.
Outcomes for elderly patients with acute myeloid leukemia who underwent allogeneic hematopoietic stem cell transplant (allo-HCT) have improved significantly over time. Relapse incidence and non-relapse mortality decreased, while leukemia-free survival and overall survival increased steadily between 2000 and 2021. These improvements wer...
A study of older adults in Medicare Advantage plans found that both members of a couple tend to stick with each other's enrollment decisions. The researchers analyzed data from over 1,800 couples and found that about 80% of Partner A individuals stayed in the same plan, and among those who changed, most partners did as well.
Medicare expenditures were higher for Black and Hispanic individuals compared to whites, with average total costs ranging from $136,326 to $165,730. The analysis attributed these differences to greater use of high-cost care during the last year of life.
A new study suggests that loneliness is comparable in harm to smoking over 15 cigarettes a day and has negative effects on physical and mental health. Primary care clinicians can play an important role in developing and maintaining social connections for patients experiencing loneliness.
A recent study found that digital reminders for flu vaccination increased vaccination rates among older adults in Denmark by one percentage point. However, it did not improve clinical outcomes, including hospitalization and death rates.
A study published in American Psychologist reveals that middle-aged Americans experience high levels of loneliness, with baby boomers reporting the highest overall levels. The research suggests that loneliness is a persistent issue across generations in both the US and Europe.
Researchers at Ohio State University found that eating fatty food before surgery triggers an inflammatory response in the brain, leading to impaired memory function. The study also showed that taking a DHA omega-3 fatty acid supplement can prevent these effects.
Researchers used single-cell RNA sequencing to analyze the effects of APC treatment on AD transgenic mice, revealing alterations in glial cells and upregulated genes associated with AD progression. APC treatment downregulates inflammatory processes and recovers nervous system functions.
A first-of-its-kind study uses gait analysis to detect subtle impairments in older adults with mild cognitive impairment, suggesting curved path walking as a more sensitive detection method. The novel system employs a non-invasive depth camera to record gait and provides detailed information on functional performance.
Experts from the University of Birmingham have devised a blueprint for efficient evacuation of elderly people in flood-threatened cities. The study highlights significant differences in evacuation patterns between Shanghai and New York City, emphasizing the need for risk-informed planning to protect vulnerable populations.
A new study has revealed a molecular fingerprint of biological aging, shedding light on why people age differently. The researchers identified 25 metabolites that can reflect biological age, known as the Healthy Aging Metabolic (HAM) Index, which was found to be more accurate than other aging metrics.
Research shows elderly patients in rural areas have higher mortality rates when discharged under pressure, particularly in municipalities with fewer than 10,000 inhabitants. The study highlights the need for better municipal services and care facilities to address the aging crisis in Norway.
A new poll suggests that more than half of people aged 50-80 taking aspirin don't have cardiovascular disease, raising concerns about the effectiveness of routine aspirin use. Guidelines now focus on those with a history of cardiovascular issues or high risk due to personal health and family history.
A University of Ottawa study found that older adults understand emoji meanings but are hesitant to use them due to low confidence and technical expertise. The research suggests promoting emoji use can combat ageism and reduce loneliness.
A study published in PLOS ONE found that higher Body Mass Index (BMI) is significantly associated with worse mental health in women, particularly among middle-aged and older adults. The research adjusted for lifestyle and demographic factors, suggesting a stronger link between excess weight and mental health issues in this population.
A new study from the University of Surrey warns that Applied Theatre practices can encourage ageism by neglecting participants' present experiences and agency. The research proposes a new Anti-Ageism Praxis (AAP) framework to address these concerns, emphasizing co-creation, focus on present responses, and challenging stereotypes.
A new approach to menopause is needed, focusing on empowering women with high-quality information and empathic clinical care. The experience of menopause varies for each person, and an individualised approach can help women navigate this life stage.
A study by Texas A&M University found that only 9% of older Americans had been vaccinated against RSV prior to this fall and winter. The study also revealed that men were more likely to be vaccinated than women, and those who were vaccinated had higher levels of concern about the disease.
A new study from the University of East Anglia found that older adults with worse spatial orientation ability experience greater difficulty when making turns across oncoming traffic, which is a significant risk factor for fatal road traffic accidents. Spatial orientation skills are essential for mentally determining position and vehicl...
The study highlights a substantial increase in recurring and chronic food insecurity among US families with older adults over the past 20 years. This trend has significant implications for health policy and programmatic strategies to address food insecurity in this population.
A new study by University of Gothenburg researchers shows that non-profit organizations provide the highest-quality elderly care in Swedish residential care homes. These homes have the highest staff density, most competent care staff, and highest resident satisfaction compared to homes run by profit-making companies.
A study reveals that feeling young appears to reduce ageism among older adults, but those who invest in appearance are more likely to experience negative outcomes. Those who feel younger score higher on positive age-related experiences and lower on negative ageism, while those who look older face increased negative ageism and poor health.
A recent study found that intergenerational mentorship programs can help overcome ageism in healthcare by providing meaningful connections between older adults and medical students. The programs, which involve younger students working with older mentors, help to break down stereotypes and promote a better understanding of older people'...
A recent study published in Psychology and Aging found that people who identify themselves as looking younger have more positive experiences related to aging, such as being asked for advice and wisdom. On the other hand, those who feel older experience more negative interactions and age-based discrimination.
A recent study from Amsterdam UMC and the University of Glasgow found that loneliness increases physical frailty, leading to a higher risk of depression, falls, and cognitive decline in older adults. The research analysis more than 130 studies and revealed that reduced social functioning is associated with physical decline in older adu...
A new study suggests that walking through historically Black neighborhoods while reminiscing can improve cognitive function and mood in older Black adults. The program, known as SHARP, combines exercise, social connection, and active reminiscence to make a cumulative impact on health.
Researchers discovered that the vitamin D/vitamin D receptor pathway protects enterocytes during aging, reducing ISC proliferation and centrosome amplification. This study provides insights into the molecular mechanisms underlying healthy aging in Drosophila.
A new study by Baycrest and the University of Toronto suggests that talking speed is a more important indicator of brain health than difficulty finding words. Changes in general talking speed may reflect changes in the brain, indicating its importance in detecting cognitive decline faster.
A new study found that only about half of older adults with a terminal prognosis received palliative home care, highlighting the need for improved detection and support. The researchers developed a tool called RESPECT to help identify frail individuals in need of palliative care.
A new study by Johns Hopkins University reveals that vision impairment is linked to increased symptoms of depression and anxiety, as well as social isolation among older adults. The research emphasizes the need for enhanced support and care for individuals with vision impairment.
The study of 5,951 women aged 63 to 99 found that higher levels of physical activity and lower amounts of sedentary time were associated with reduced heart failure risk. Promoting regular physical activity and limiting sedentary time may be a prudent strategy for primary prevention of heart failure in older women.
A new study found that chronic exposure to PM2.5 is associated with increased risk of hospital admission for various cardiovascular conditions, particularly ischemic heart disease and cerebrovascular disease. The study suggests that lowering annual average PM2.5 levels could decrease overall cardiovascular hospitalizations by 15%.
A new study from the University of Toronto found that older Canadians with a history of stroke experienced depression during the COVID-19 pandemic. Among those with no lifetime history of depression, immigrant status and family stressors were associated with an increased risk of incident depression.
Prescription opioids linked to increased risk of serious falls among adults, with older individuals most vulnerable. Targeted prevention efforts may be most effective within the first month after opioid initiation.
A new study by University of Eastern Finland identifies four main drivers for home care worker turnover: mismatch between client needs and available resources, digital systems taking up time, inflexible work demands, and ethical burden. Home care workers seek personal management and consideration of employee and client needs.
A study published in European Geriatric Medicine found that self-monitoring with an accelerometer and feedback significantly improved physical activity among elderly individuals requiring long-term care. The intervention group took more steps, spent less time sitting, and engaged in light physical activity compared to the control group.
Research shows that lowering doses and adjusting chemotherapy schedules for older adults with advanced cancer can reduce toxic side effects and preserve daily functions. Over 30% of patients benefited from treatment regimen modifications, with a 15% reduced risk of serious clinician-rated toxic effects.
A new study suggests that caregivers can establish a safe and workable mealtime routine for people with dementia living at home by reducing distractions, clearing away clutter, and leveraging community-based nutrition programs. The strategies aim to address the complex factors surrounding mealtime in the home, including cognitive impai...
A new review of 12 studies involving 2,901 participants found that tai chi was more effective than conventional exercise in improving functional mobility and balance. The study also identified specific factors, such as shorter duration and Yang-style focus, that contributed to the benefits.
A new study from Uppsala University found that people who have had herpes virus are twice as likely to develop dementia as those who have never been infected. The researchers studied 1,000 70-year-olds over 15 years and confirmed previous research on the potential link between herpes and dementia.
A study of 61,000 adults aged 45 or older found that those who adhered to physical activity guidelines before the pandemic had lower odds of developing or being hospitalized for COVID-19. This suggests that higher prepandemic physical activity levels may be linked to reduced risk of SARS-CoV-2 infection and hospitalization.
A comprehensive study will examine how young caregivers balance educational responsibilities with care for older relatives, influencing academic performance and decision-making. The InterCare project aims to raise awareness about the challenges faced by this often-overlooked group, including feelings of shame and guilt.
A cohort study of older adults found that those who followed recommended exercise guidelines before the pandemic had significantly lower odds of being infected or hospitalized from COVID-19. Physical activity was associated with a 10% lower risk of infection and 27% lower risk of hospitalization.