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Life Sciences

Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.

447,757 articles | 2542 topics

Health and Medicine

Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.

431,843 articles | 751 topics

Social Sciences

Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.

260,756 articles | 745 topics

Physical Sciences

Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.

257,913 articles | 1552 topics

Applied Sciences and Engineering

Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.

225,386 articles | 998 topics

Scientific Community

Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.

193,043 articles | 157 topics

Space Sciences

Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.

29,662 articles | 175 topics

Research Methods

Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.

21,889 articles | 139 topics

Mathematics

Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.

3,023 articles | 113 topics

New method for examining cost-effectiveness of new drugs for chronic illnesses

Researchers developed a new approach to analyze drug effectiveness data, providing insights into the cost-effectiveness of newer and older anti-epileptic drugs. The study suggests that two older drugs, valproate and carbamazepine, are likely to be more cost-effective for newly diagnosed patients with partial seizures.

Studies show benefits of newborn screening for 'bubble boy disease'

Researchers found that newborn screening for SCID could be cost-effective due to the benefits of early diagnosis and the potential to save lives. A two-tiered strategy combining existing tests has been shown to improve accuracy without increasing costs, making it a promising approach for nationwide screening programs.

Team care more cost-effective than usual care for depression

A team care model, including a case manager and primary care provider, results in better outcomes for treating clinical depression. The IMPACT program provides powerful health benefits, including decreased depression and pain, improved physical functioning, and better overall quality of life.

Meta Quest 3 512GB

Meta Quest 3 512GB enables immersive mission planning, terrain rehearsal, and interactive STEM demos with high-resolution mixed-reality experiences.

New insights into cost-effectiveness of implanted heart device

Researchers found that ICDs provide value in appropriate patients, but more research is needed to identify high-risk patients who would benefit most from the therapy. The study suggests that ICD use could be more cost-effective with lower implantation costs or extended device lifespan.

The Basel stent kosteneffektivitäts trial (BASKET)

The BASKET trial compares the costs and outcomes of drug-eluting stents (DES) and bare-metal stents (BMS) in 826 patients with PCI. The study aims to identify patient subgroups where DES are cost-effective, potentially impacting daily practice and preferences.

Comments sought on draft federal IT security standard

The National Institute of Standards and Technology (NIST) has released a draft federal IT security standard, FIPS Publication 200, to aid in FISMA compliance. The document provides guidelines for minimum security requirements and a risk-based approach for selecting security controls.

Apple iPhone 17 Pro

Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.

Study examines cost-effectiveness of HPV testing in four European countries

A study examines the cost-effectiveness of HPV testing in France, Italy, the Netherlands, and the UK, finding both triage and combination strategies to be more effective than current cytology-based screening programs. The cost-effectiveness ratios range from $9,800 to $75,900 per year of life saved, depending on the screening interval.

UCLA study assesses cost-effectiveness of Hepatitis B drugs

The study found that the newest drug therapy – adefovir – was not cost-effective when taken alone but became very cost-effective when reserved as a second-line agent in people who develop viral resistance for lamivudine. The hybrid treatment strategy of lamivudine and adefovir is also a viable option.

Statin therapy cost-effective for a wider range of individuals

A new study finds that statin therapy can significantly reduce hospitalization costs and costs of major vascular events. The cost-effectiveness of treatment varies depending on individual risk levels, with lower-risk groups potentially benefiting from statins.

Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C)

Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C) keeps Macs, tablets, and meters powered during extended observing runs and remote surveys.

Cost-effectiveness of drugs may vary across borders

A new study assesses the cost-effectiveness of pharmaceuticals in different countries, highlighting the importance of considering location-specific factors. The findings emphasize that economic evaluations are not transferable across borders, requiring repeated studies to determine cost-effectiveness.

Tip sheet for the Annals of Internal Medicine, March 1, 2005

Two studies examine the prevention of type 2 diabetes mellitus, a condition that affects millions of Americans. Researchers found positive lifestyle changes lowered risk among nonsmokers but not smokers. A computer simulation determined the diet-exercise program and metformin therapy were cost-effective options.

The BIOS Initiative - open source biotechnology is born

The BIOS Initiative provides a new licensing mechanism that encourages sharing of core tools of innovation, empowering researchers worldwide. The launch of BioForge, an online collaborative research platform, enables scientists to work together to craft new technologies within a protected commons.

Apple AirPods Pro (2nd Generation, USB-C)

Apple AirPods Pro (2nd Generation, USB-C) provide clear calls and strong noise reduction for interviews, conferences, and noisy field environments.

Routine HIV screening should be expanded, study finds

A new study recommends expanding routine HIV screening to settings with low prevalence rates due to its cost-effectiveness. The study found that even at low prevalence levels, regular testing can provide important health benefits. Additionally, the researchers suggest that screenings should be expanded to reduce the transmission of the...

January/February Annals of Family Medicine tip sheet

This article discusses the association between non-hazardous alcohol consumption and injury, as well as barriers to treating depression among young adults. Studies find that excessive drinking causes significant injuries, while negative attitudes towards treatment may prevent youth from accepting diagnosis and care.

SAMSUNG T9 Portable SSD 2TB

SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.

Is home visiting an effective strategy?

A meta-analytic review found that home visiting programs enhance parenting behaviors, increase educational attainment, and boost children's cognitive and social skills. While the benefits are statistically significant, the magnitude of the impact varies.

The high price of fatigue

A study of 56,000 people from Wichita, Kansas found that Chronic Fatigue Syndrome causes a significant burden on the economy, with lost productivity estimated at $9.1 billion annually. The syndrome affects approximately 450,000 individuals nationwide, resulting in substantial economic losses and reduced household income.

Garmin GPSMAP 67i with inReach

Garmin GPSMAP 67i with inReach provides rugged GNSS navigation, satellite messaging, and SOS for backcountry geology and climate field teams.

Study findings question COX-2 drug cost effectiveness

Researchers at Express Scripts found that COX-2 prescribing physicians often co-prescribe gastroprotective drugs, contradicting expert estimates. This challenges the use of expert opinion in estimating practice pattern model inputs and warrants re-evaluation of COX-2 cost-effectiveness models.

NIH consensus panel confirms effectiveness of total knee replacement

The NIH consensus panel confirms the effectiveness of total knee replacement surgery, highlighting the importance of surgeon volume and proper prosthesis alignment to minimize long-term complications. Computer navigation technology may eventually reduce malalignment risks but is currently unproven and costly.

Innovative shuttle bus debuts in Washington, D.C.

The new yellow bus features alternative fuel, a low floor, and complies with the Americans with Disabilities Act (ADA), providing easy accessibility for passengers. The bus is designed to reduce dependence on foreign energy sources and protect national parks' pristine environment.

Rigol DP832 Triple-Output Bench Power Supply

Rigol DP832 Triple-Output Bench Power Supply powers sensors, microcontrollers, and test circuits with programmable rails and stable outputs.

Habitat loss and reserve network selection

A novel method integrates habitat modelling and spatial population dynamics in reserve-network design to consider the impact of habitat loss on species survival. This approach represents a step towards more realistic consideration of species survival when selecting reserve networks.

Annals of Internal Medicine, tip sheet, June 17, 2003

A new study suggests that pneumococcal vaccination can save medical costs for individuals aged 50 to 64, particularly those at high risk of pneumococcal disease. The cost-effectiveness of vaccination is comparable to other preventive services in this age group.

Apple Watch Series 11 (GPS, 46mm)

Apple Watch Series 11 (GPS, 46mm) tracks health metrics and safety alerts during long observing sessions, fieldwork, and remote expeditions.

Little value seen in CT scans for lung cancer screening

A recent study found that annual whole-body CT scanning for lung cancer screening may not be effective in saving lives, as the costs outweigh the benefits. The researchers estimated that only smokers who started quitting at age 55-65 saw significant cost-effectiveness in screening.

GQ GMC-500Plus Geiger Counter

GQ GMC-500Plus Geiger Counter logs beta, gamma, and X-ray levels for environmental monitoring, training labs, and safety demonstrations.

Cigarette tax hike could save millions of lives

A recent study estimates that cigarette tax hikes could prevent between 5 million to 16 million tobacco-related deaths globally. The greatest savings would be in low- and middle-income countries, with the greatest impact on young smokers. Price increases are considered the most cost-effective anti-smoking intervention.

Cost-effectiveness assessments important for HIV response in Africa

A study assessing existing data on HIV/AIDS interventions found that cost-effectiveness varies greatly between interventions. Some interventions, such as selective blood safety measures and targeted condom distribution, can prevent a case of HIV/AIDS for under $11 and gain over $1 in disability-adjusted life-years (DALYs) per dollar spent

Fluke 87V Industrial Digital Multimeter

Fluke 87V Industrial Digital Multimeter is a trusted meter for precise measurements during instrument integration, repairs, and field diagnostics.

Time to vaccinate everyone under 30 against smallpox?

Researchers found that immunizing 50-75% of Americans aged 1-30 could save hundreds of lives compared to ring vaccination alone. The study suggests mass vaccination campaigns targeting young people may be cost-effective in preventing deaths from a potential smallpox attack.

Annals of Internal Medicine, tip sheet, January 15, 2002

A study in Annals of Internal Medicine finds that accurate profiling of physician care depends on study design, and that most quality initiatives fail to adjust for patient characteristics. Additionally, researchers estimate that colonoscopy is a cost-effective strategy for investigating rectal bleeding in young people

USF report grades health performance of Florida's counties

The USF report ranks 66 Florida counties based on overall health ratings, with top-scoring counties having better healthcare and lower poverty rates. The report also highlights deficiencies in high-performing counties, such as lack of health screening and primary care measures.

Aranet4 Home CO2 Monitor

Aranet4 Home CO2 Monitor tracks ventilation quality in labs, classrooms, and conference rooms with long battery life and clear e-ink readouts.

Stanford study investigates treatment cost effectiveness after heart attack

A new Stanford University study analyzed the costs and benefits of two treatments: implantable cardioverter defibrillators (ICDs) and the drug amiodarone. ICDs were found to be the most effective in preventing sudden cardiac death, but also came with the highest costs. Amiodarone produced intermediate benefits and costs.

Annals of Internal Medicine, tip sheet, October 16, 2001

A study of 2,437 HIV-infected adults found that patients with case managers had fewer unmet needs and higher use of HIV medications. Screening for hereditary colorectal cancer has been shown to work and may be cost-effective, particularly for relatives of affected individuals.

New Penn State approach steadies floors too flexible for comfort

Dr. Linda M. Hanagan's innovative approach uses active control systems to dampen vibrations in existing buildings, reducing costs and time required compared to traditional stiffening or thickening methods. The system can be applied quickly, often taking less than a week to fix the problem.

Creality K1 Max 3D Printer

Creality K1 Max 3D Printer rapidly prototypes brackets, adapters, and fixtures for instruments and classroom demonstrations at large build volume.

Study finds cochlear implants cost-effective in children

Researchers at Johns Hopkins Medicine found that cochlear implants improve quality of life and save $50,000+ over a child's lifetime. The study provides evidence that pediatric cochlear implantation is highly cost-effective from a societal perspective.

Annals of Internal Medicine, Tip Sheet, May 16, 2000

Two studies in Annals of Internal Medicine explore cost-effectiveness of statins on specific populations. Statin therapy was found to be reasonably cost-effective for patients aged 75-84 years old with a history of heart attack, increasing life expectancy by four months while costing $18,800 per quality-adjusted life year. Cost-effecti...

Kestrel 3000 Pocket Weather Meter

Kestrel 3000 Pocket Weather Meter measures wind, temperature, and humidity in real time for site assessments, aviation checks, and safety briefings.

Govnews Project Takes Democracy Into Cyberspace

The GovNews Project introduces a new category on Usenet, facilitating the delivery of official notices, news, announcements, reports, and publications from government agencies. Millions of people will now be able to participate in discussions on topics like privatization, procurements, and environmental issues.

First-Light Declared At Hobby-Eberly Telescope

The Hobby-Eberly Telescope has taken its first look at the universe, demonstrating its novel design and paving the way for groundbreaking astronomical discoveries. The telescope's innovative design eliminates expensive features while tracking objects with precision, allowing for efficient and cost-effective large-scale observations.

Sky & Telescope Pocket Sky Atlas, 2nd Edition

Sky & Telescope Pocket Sky Atlas, 2nd Edition is a durable star atlas for planning sessions, identifying targets, and teaching celestial navigation.

UH Professor's Study May Help Scientists Predict Earthquakes

Researchers have developed a new technique to predict earthquake magnitude based on rock structure, providing more accurate assessments of seismic risk. By analyzing data from 37,000 earthquakes in southern California, the team created 3D images of subsurface rock formations that reveal varying maximum depths along and across faults.