Articles tagged with Dementia
A recent study published in the Journal of General Internal Medicine found that adults with both diabetes and major depression are more than twice as likely to develop dementia compared to those with diabetes alone. The study, led by Dr. Wayne Katon, suggests that major depression doubles the risk of dementia in adults with diabetes.
The event promotes positive attitudes on ageing, using new technologies to improve elderly independence and wellbeing. Events include 'Improving everyday life' and 'Dementia: Don't fear it', discussing loneliness, dementia, and ageism.
Researchers are developing new assessment tools in British Sign Language (BSL) to identify dementia among Deaf people, who often face unique challenges in accessing care and support. The study aims to improve early diagnosis and provide tailored services for this underserved population.
The study found that dementia incidence rates increase exponentially with age in both men and women past age 90. Researchers estimate that the number of Americans aged 90 and older will reach 8.7 million by 2050, making dementia a significant public health concern.
A study found that nearly four in 10 TIA and minor stroke patients exhibit deficits in executive functions, including speed of mental processing and abstraction. Researchers emphasize the importance of using specific measures to detect cognitive impairment in these patients.
A study of 2,929 individuals aged 65+ found that hospitalization for acute or critical illness was associated with lower cognitive scores and higher dementia risk. Noncritical illness hospitalizations had a 40% higher risk of dementia compared to never-hospitalized participants.
A University of Michigan study found that untreated visual disorders in the elderly are significantly more likely to develop Alzheimer's disease. Early treatment of these problems may delay the onset of dementia, but many elderly individuals lack adequate vision coverage.
Advanced dementia patients are more likely to receive feeding tubes at larger, for-profit hospitals. Research found a higher rate of feeding tube insertion in these hospitals compared to others.
A study by Brown University researchers highlights the need for better decision-making in end-of-life care, particularly for hospitalized nursing home residents with advanced dementia. The study found that feeding tubes are used variably among hospitals, with larger or for-profit hospitals using them more frequently.
A study of 990 older adults found that hypertension predicts dementia progression in those with executive function deficits, but not in those with memory dysfunction. Control of hypertension may decrease the projected rate of dementia progression by half.
A new study published in Neurology suggests that cognitive decline, regardless of dementia diagnosis, may increase the risk of stroke. The researchers found that men who scored lower on a mental test measuring planning and executive function were three times more likely to experience a stroke or brain infarction.
Researchers developed two step-by-step training programmes to help dementia patients regain eating skills. The study showed that both methods reduced feeding difficulty and improved nutritional assessment compared to no intervention, offering a promising approach to addressing nutritional problems in older adults with dementia.
A study in Brazil found that heavy alcohol use among the elderly is associated with more memory and cognitive problems than mild-to-moderate drinking, particularly among women. The study also revealed that older adults continue to drink throughout their lives.
Research found that patients with Alzheimer's were 4.6 times more likely to have mental lapses than those without the disease. Cognitive fluctuations include excessive daytime sleepiness, staring into space, and disorganized or illogical thinking.
A study found that people with three or four of the following symptoms are more likely to have Alzheimer's disease: feeling drowsy, disorganized thinking, staring into space, and lethargy. Those with mental lapses also had more severe symptoms and poorer cognitive performance than those without lapses.
A recent study published in the British Medical Journal found that angiotensin receptor blockers (ARBs) are associated with a significant decrease in Alzheimer's disease and dementia occurrence. Patients taking ARBs had up to a 50% lower chance of developing dementia compared to those on other medications.
Researchers found a link between a specific gene variation and slower memory decline, as well as a lower risk of developing dementia and Alzheimer's disease. The study suggested that this protective association may be due to the gene's role in lipid metabolism.
Research from the University of Pittsburgh Graduate School of Public Health found that high blood pressure is associated with white matter abnormalities in the brain, which can lead to dementia. Women who had hypertension at age 65 were more likely to develop dementia eight years later.
Research from the Women's Health Initiative Memory Study finds elevated blood pressure increases white matter lesions, a known risk factor for dementia. Maintaining normal blood pressure may help prevent brain damage and associated cognitive decline.
A recent study found that nursing home residents with the highest antipsychotic prescribing rates are more likely to receive the medication, with 16.4% of those without a clinical indication for therapy receiving it. The study suggests that organizational culture may play a role in encouraging high prescribing rates.
The use of atypical antipsychotics among elderly patients with dementia decreased significantly following FDA advisory in 2005. This decline resulted from a 34% yearly increase in antipsychotic mentions before the warning, followed by a 19% decrease in dementia-specific mentions after the warning was issued.
Two studies found moderate physical activity in midlife reduces risk of mild cognitive impairment. A six-month high-intensity aerobic exercise program improves cognitive function in individuals with the condition. Moderate exercise is associated with a 39% reduction in odds of developing mild cognitive impairment.
A new study found that healthy older adults with subjective cognitive impairment (SCI) are 4.5 times more likely to progress to mild cognitive impairment (MCI) or dementia than those without SCI. Over a seven-year period, 54% of SCI individuals showed further cognitive decline, compared to 15% of non-SCI individuals.
A recent study published in JAMA found that Ginkgo biloba supplementation did not slow the rate of cognitive decline in older adults with normal cognition or mild cognitive impairment. The researchers analyzed data from over 3,000 participants and found no evidence of an effect on global cognitive change or specific cognitive domains.
A recent study found that people with Alzheimer's disease were less likely to develop cancer, while those with cancer were less likely to develop Alzheimer's. The study suggested that these two conditions may be linked, offering potential avenues for new treatments and a better understanding of both diseases.
Researchers identify ineffective communication strategies that can worsen problem behaviors in family members with dementia. Effective communication, on the other hand, can resolve misunderstandings and reduce distress. The study aims to develop empirically derived communication interventions for caregivers targeting both problems.
A new study published in JAMA found that tarenflurbil, a drug intended to reduce amyloid-β levels, showed no benefit in slowing cognitive decline or improving daily activities in patients with mild Alzheimer's disease. The researchers concluded that interventions targeting amyloid have not yet been shown to alter the course of AD.
Researchers from Boston University School of Medicine found that higher leptin levels are associated with a lower incidence of Alzheimer's Disease and dementia. The study suggests that leptin may have beneficial effects on brain development and function, potentially opening pathways for preventive and therapeutic interventions.
A study found that individuals with higher leptin levels had a reduced incidence of Alzheimer's disease and dementia. Higher leptin levels were also associated with increased total cerebral brain volume.
Two new studies suggest that late-life dementia is a complex disease resulting from multiple processes, including Alzheimer's disease, vascular brain injury, and Lewy body disease. Higher levels of leptin may also be linked to reduced risk of Alzheimer's disease, according to the findings.
A new study found that cancer patients with dementia have a lower survival rate than those without dementia, even after controlling for age, tumor type, and stage. Patients with mild cognitive impairment can still live independently for nearly four and a half years, while those with moderate to severe dementia have an average survival ...
A new imaging test has detected early Alzheimer's disease in older adults, which is likely to progress into symptomatic Alzheimer's disease. The test uses Pittsburgh Compound B (PiB) to bind to beta-amyloid plaques in the brain, identifying individuals who are at risk of developing dementia.
A study of 15,000 elderly individuals in 11 low- and middle-income countries found dementia to be the largest contributor to disability, followed by stroke, limb impairment, and depression. Chronic diseases, including those of the brain and mind, pose significant challenges for carers and society.
The ACT study focuses on finding ways to delay or prevent dementia, including Alzheimer's disease. Recent findings highlight the role of vascular disease and controlling high blood pressure in reducing the risk of late-life dementia.
A study published in PLOS Medicine found that dementia is often associated with mixed pathological changes, including Alzheimer's and vascular dementia. The researchers estimated that drugs targeting specific pathologies may have limited impact on the overall burden of dementia.
A package of continuing care is essential for managing dementia in LMICs, comprising diagnosis, regular needs assessments, physical health checks, and carer support. The authors highlight the importance of early detection and treatment of behavioral and psychological symptoms.
A recent study published in Neurology reveals that nearly 42% of participants with frontotemporal dementia had some family history, while only 10% were affected by an autosomal dominant gene. The study also found that behavioral problems are more likely to be hereditary than language problems.
A study published in Journal of the American Geriatrics Society found that older patients with dementia are diagnosed with flu less frequently, have shorter hospital stays, but a higher rate of death. The study highlights the need for refined guidelines on flu immunization and treatment in this vulnerable population.
Palliative care is crucial for dementia patients as they often suffer from untreated pain and symptoms due to their inability to report their condition. The need for improved symptom management, emotional support, and family support has been emphasized by experts.
A study published in the New England Journal of Medicine found that dementia is a terminal illness characterized by uncomfortable symptoms and high mortality rates. The research highlights the need for improved palliative care in nursing homes to reduce physical suffering and enhance communication with family members.
Researchers found that declines in visuospatial skills and cognitive abilities can occur years before clinical diagnosis of Alzheimer's disease. These findings suggest that conventional methods for diagnosing the disease may not be sensitive to early manifestations of the condition.
A systematic review found that post-stroke dementia rates varied greatly, but were closely related to stroke characteristics and complications. The authors suggest that optimum acute stroke care and secondary prevention measures could reduce the burden of dementia. Further studies are needed to identify independent predictive factors.
A new study from UAB researchers suggests that individuals with mild cognitive impairment (MCI) who struggle with financial management skills may be at risk for developing Alzheimer's disease. The study found that MCI patients who declined in financial capacity over a year were more likely to progress to Alzheimer's.
Researchers discovered a link between declining financial skills and the development of Alzheimer's disease. Participants with mild cognitive impairment (MCI) who showed poorer money management abilities were more likely to progress to dementia.
A new study reveals that communication problems and misunderstandings are the primary causes of physical strain in dementia care. Effective communication techniques, such as explaining instructions with different words and using body language, can help reduce this strain.
A study published in Archives of Neurology found that those with more difficulties performing daily activities are at increased risk for progressing quickly to dementia. Functional impairment at baseline was the only factor associated with conversion from mild cognitive impairment to dementia.
The European College of Neuropsychopharmacology emphasizes the need to address mental health issues due to work-related stress and increasing economic troubles. The prevalence of mental disorders is expected to rise, affecting millions worldwide.
Research by the Universities of Exeter and Queensland shows that membership of social groups has a positive impact on health and well-being. Studies have found that people who maintain valued group memberships recover more positively after a stroke, are happier in care homes, and experience improved mental health.
A new study found that healthy older brains are similar in size to those of younger individuals, contrary to previous findings. The research tested participants without neurological problems and used MRI scans to measure brain areas. Cognitive decline was measured by drops in performance on certain tests.
British scientists have discovered two new genes associated with Alzheimer's disease, CLU and PICALM. These findings provide valuable new leads in the race to find treatments and possibly cures for the common form of Alzheimer's disease.
A new study by Johns Hopkins researchers reveals that HIV subtype D is associated with a significantly higher likelihood of developing dementia. The study found that nearly all (89%) patients infected with subtype D developed dementia, whereas only about 24% of those infected with subtype A showed signs of the condition.
A recent national survey found that physicians inaccurately believed in the FDA approval status of 22 drug-indication pairs, including lorazepam for chronic anxiety and quetiapine for dementia with agitation. The study highlights the need for better methods to inform physicians about the level of evidence supporting off-label drug use.
A study mapping brain activity networks in Alzheimer's disease (AD) and frontotemporal lobar degeneration (FTLD) patients reveals distinct changes in communication between brain areas. AD patients show more random network organization, while FTLD patients display a more ordered structure, challenging the understanding of these diseases.
A large multicentre study has confirmed that a combination of proteins in the cerebrospinal fluid can reliably identify patients with early symptoms of dementia who will later develop full-blown Alzheimer's disease. The findings may lead to new medicines and point-of-care diagnostics.
Elderly individuals with a Mediterranean diet rich in fruits, vegetables, and fish, and high levels of physical activity had a significantly lower risk of developing Alzheimer's disease. Higher adherence to the Mediterranean diet was associated with slower cognitive decline but not decreased dementia risk.
A four-decade study of 9,844 participants found that high cholesterol levels in midlife significantly increase the risk of Alzheimer's disease and vascular dementia later in life. Borderline elevated cholesterol levels also raise risk for late-life vascular dementia.
A study published in Neurology found that engaging in brain-exercising activities such as reading and playing card games can delay the onset of rapid memory loss in people with dementia. Participants who engaged in more activities experienced a slower decline in cognitive function.
Researchers created a fly model to study Parkinson's-associated dementia, finding that sleep loss caused long-lasting cognitive impairments. Curcumin blocked this effect, restoring normal learning abilities in genetically modified flies.
Elevated levels of ECE-2 enzyme are linked to reduced blood flow in the brain, a hallmark of Alzheimer's disease. The findings suggest that drugs blocking endothelin-1 may also benefit Alzheimer's patients.
Researchers found that centrally-acting ACE inhibitors, which cross the blood-brain barrier, may reduce inflammation and cognitive decline in patients with hypertension. These medications showed a significant association with lower rates of mental decline, particularly those taking drugs like captropril and lisinopril.