The University of Colorado at Boulder is developing a new communications technology called Disruption Tolerant Networking (DTN) with NASA, which will extend Earth's Internet into outer space and across the solar system. The technology enables automated future communications capabilities for lunar habitation and surface exploration.
A new study found that women who deliver prematurely have higher levels of phthalates in their urine compared to those who carry to term. The researchers analyzed data from Mexican women and discovered a significant association between phthalate exposure and premature birth.
A new study published in CMAJ found significant muscle injury in patients taking statins, even in those without elevated creatine phosphokinase levels. Researchers suggest a subgroup of patients may be more susceptible to statin-associated myotoxicity and call for alternative treatment strategies.
Researchers identified CST5 as a candidate tumor suppressor gene induced by vitamin D3 in human colon cancer cells. The protein cystatin D inhibits cancer cell growth and is responsible for some of vitamin D3's anticancer effects.
Researchers engineered mice with a persistent wound-like skin condition to study tumor growth. The study found that chronic skin wounds promote skin tumors by secreting molecules that activate dermal cells and increase inflammation. Notch1 signaling plays a critical role in this process, suggesting potential complications for drug design.
Researchers found that a short Q뺪bout family history can predict a patient's approximate risks for developing depression, anxiety, or substance abuse disorders and their future illness severity. Family history is the quickest and cheapest way to sort out whether mental illnesses will run in families.
A CU-Boulder study found that chemicals released by the brain's immune system can cause chronic seizures in people who have suffered a traumatic head injury. The research suggests that temporarily shutting down the immune response could prevent the development of acquired epilepsy.
Researchers found that combining antidepressants with electroconvulsive therapy (ECT) improves depression symptoms more than using ECT alone, reducing memory problems, particularly when using nortriptyline or unilateral ECT on the right side of the brain.
Researchers found that patients with trichotillomania reported significantly reduced hair-pulling after taking the supplement for 12 weeks. Fifty people participated in a double-blind study, with 56% reporting improved symptoms.
Researchers have developed a new leukemia therapy targeting cancer stem cells that drive acute myeloid leukemia (AML) growth. The antibody therapy, which specifically targets the CD123 protein, has shown promising results in laboratory models and clinical trials.
The Mayo Clinic Cancer Center has received a $28 million National Cancer Institute (NCI) funding grant for five years. This award extends the center's designation as a comprehensive cancer center, enabling it to continue delivering outstanding care and research programs across its three US sites.
Despite significant research efforts, no effective way to prevent or treat delirium has been identified. The study found that only 13 randomized controlled studies on promising drugs were conducted from 1966 to 2008, and none of them were effective in preventing or treating delirium.
A new study provides direct evidence of significant fish consumption by early modern humans in China dating back 40,000 years. The analysis of collagen from a bone found in Tianyuan Cave near Beijing suggests that this individual was a regular fish consumer.
Researchers use DNA in feathers to create tags that reveal population sizes, parentage, roosting patterns, and sex ratios. This technique allows for easier study of larger populations without capturing birds.
A Swedish study found improved long-term survival rates among patients with intact abdominal aortic aneurysms who underwent surgical repair between 1987 and 2005. Patients in their 80s and males experienced higher relative five-year survival rates, likely due to atherosclerosis, whereas advances in postoperative care and endovascular a...
Researchers have identified a potential tumor suppressor gene, CST5, that mediates the anticancer effects of vitamin D3 in human colon cancer cells. The study found that cystatin D protein inhibited the growth of colon cancer cells and was induced by vitamin D3, suggesting its role as a candidate tumor suppressor gene.
The Centre for Vulnerable Women and Children in Dharavi, Mumbai, addresses the needs of crisis victims by prioritizing family unity. Successful intervention relies on strong partnerships with healthcare providers, law enforcement, and community organizations.
A recent study found that online computer games promoting healthy foods and beverages can encourage children to choose nutritious snacks. The research involved 30 low-income African American children who played a game rewarding healthy food choices versus one promoting unhealthy options.
Researchers at the University of Alabama at Birmingham found that atrial fibrillation significantly increases hospitalization due to worsening heart failure in patients not receiving beta-blockers. However, the risk of all-cause mortality was similar between those with and without atrial fibrillation.
Researchers have identified key signals supporting long-term survival of breast cancer cells after they spread to the bone marrow. The study found that activity of a cancer-related enzyme called Src is associated with late-onset bone metastasis and promotes cell survival.
Astronomers analyzed gamma-rays from two dozen pulsars, including 16 discovered by Fermi, revealing unprecedented power for discovering and studying gamma-ray pulsars. The studies shed light on the nature of unidentified gamma-ray sources in our galaxy.
Researchers found that children with autism rely heavily on proprioception to learn new actions, leading to greater impairment in social skills and motor skills. This understanding can inform targeted interventions to enhance visuo-motor associations in children with autism.
A study published in Psychosomatics found that patients with severe hypoactive delirium have the worst six-month survival rate of any class of the disease. Delirium severity, rather than motoric subtype, is associated with higher risk of mortality at six months among patients without dementia.
A new study led by Memorial Sloan-Kettering Cancer Center researchers identifies the genetic function that enables breast cancer cells to survive and spread in the bone marrow. The findings support the development of therapies targeting this survival capacity, which could prevent metastasis and improve patient outcomes.
A recent study found that cardiovascular medication costs in Canada increased by 200% over the past decade, reaching $5 billion in 2020. The study highlights the need for cost-effective medications to ensure sustainable public drug insurance programs.
A 12-week study found that N-acetylcysteine significantly reduced hair-pulling symptoms in patients with trichotillomania, a condition characterized by compulsive hair-pulling and significant psychosocial problems. The treatment was well-tolerated and compared favorably to existing treatment options.
A new molecule finds and penetrates prostate cancer cells, allowing for targeted treatment and improved imaging. The targeting molecule has the potential to reduce toxic side effects and improve diagnosis of prostate cancer.
Researchers have discovered a method to deliver a natural suppressor of the immune response, HLA-G, directly to dendritic cells using microscopic beads. This approach shows promise in creating 'designer' immune cells that can tolerate transplanted organs. The therapy could potentially replace current anti-rejection drugs and improve pa...
Wake Forest University scientists have developed a new detection method for nitroxyl, which can strengthen canine heartbeats and has potential benefits for humans. The new tool will help answer questions about natural production of nitroxyl in the human body.
A recent study found that xylitol syrup can effectively prevent tooth decay in primary teeth of toddlers. The study involved 94 children aged 9-15 months and showed a significant reduction in decayed teeth among those receiving xylitol syrup, with up to 70% prevention rate.
A new study in CMAJ found that an electronic tracking system improved diabetes care and clinical outcomes for patients, with 62% showing significant improvement compared to the control group. The study also showed greater patient satisfaction with their diabetes care.
The Society for Vascular Nursing has released a comprehensive guideline for patient care of those with vascular disease, focusing on endovascular repair of abdominal aortic aneurysms. The guidelines aim to improve patient outcomes and ensure continuity of care across the population.
A study found that movie smoking exposure is associated with an increased risk of established smoking in both team sport participants and nonparticipants. Team sports participation is linked to a reduced likelihood of youths becoming established smokers.
The HPV-16/18 AS04-adjuvanted vaccine shows high efficacy against precancerous cervical lesions, with cross-protective efficacy against other oncogenic HPV types. The vaccine also demonstrates efficacy in universal mass vaccination and catch-up programmes, potentially reducing cervical cancer incidence.
Researchers studied 35 ancient tetrapods to understand anatomical changes during the transition from fish to amphibians. They found that bones changed size at different rates, resulting in reshaping of body shape over time. This study supports the idea that modern amphibians evolved through paedomorphosis and miniaturization.
Researchers discovered that parents who encourage their children to participate in high-intensity team sports have more active kids. However, girls are less likely to engage in these activities and instead spend more time watching TV or engaging in moderate household chores.
Researchers at the Virginia Bioinformatics Institute aim to create a petascale computational modeling environment to simulate billions of individuals in large social and information networks. This project seeks to improve agent-based modeling applications on 100,000+ processor architectures.
Researchers pinpointed the basolateral nucleus of the amygdala as the site where fear conditioning is encoded. The study sheds light on how fear memories are formed and may lead to new treatments for anxiety disorders.
Research at the University of Nebraska-Lincoln shows that invasive plant species like Eastern white pine can accumulate and hold onto nitrogen, leading to increased biomass and productivity. This nitrogen accumulation allows the plants to outcompete native species and invade their habitats.
Researchers discovered that certain carbohydrates on normal cells and enzymes like β3GnT1 function as tumor suppressors. Upregulation of β3GnT1 reduced tumor activity and metastasis in breast and prostate cancers. The study provides new insights into the role of complex carbohydrates in cancer.
Researchers have discovered that two microRNAs, miR-143 and miR-145, control the differentiation and growth of vascular smooth muscle cells. These findings suggest that targeting these microRNAs may be a potential treatment for diseases such as atherosclerosis and Alzheimer's disease.
A study by Rhode Island Hospital researchers found a substantial link between increased levels of nitrates in the environment and food with increased deaths from diseases such as Alzheimer's, diabetes mellitus, and Parkinson's. The study suggests that reducing nitrate levels in fertilizer and water, detoxifying food and water, may help...
Researchers at Mayo Clinic and University of California San Francisco have discovered a connection between DNA alterations on human chromosome 9 and glioblastoma. The study found that individuals with specific single nucleotide polymorphisms (SNPs) are 50% more likely to develop the aggressive brain cancer.
A new region of the genome associated with an increased risk of melanoma has been identified by researchers at Leeds University and IDIBAPS, funded by the European Commission. The study found a link between this region and skin pigmentation, as well as two previously identified regions linked to melanoma risk.
Researchers at the University of Pittsburgh have identified an enzyme inhibitor that increases cardiac progenitor cells and influences heart development in zebrafish. The findings have broad implications for understanding heart development and improving treatments for damaged or diseased tissues.
A study published in Nature Genetics found that genetic patterns on chromosomes 9 and 22 are associated with an increased risk of melanoma. People carrying these genes are around eight times more likely to develop the disease than those with no variants.
Researchers at the University of South Florida found that caffeine significantly decreased abnormal levels of beta amyloid protein in the brains and blood of Alzheimer's mice, reversing their memory impairment. Caffeine administered to elderly non-demented humans also affects their blood levels of β-amyloid.
A large-scale study has identified genetic variations across five genes as risk factors for the development of gliomas, the most frequent type of brain tumor. The study found that individuals with certain variations have a higher risk of developing glioma, with those with eight or more variations having a three-fold increased risk.
Researchers at Gladstone Institute discovered a key switch, microRNA-145 (miR-145), to turn stem cells into muscle cells that reside in blood vessel walls. This finding suggests restoring miR-145 activity could prevent artery narrowing and vessel disease.
A phase III randomised controlled trial found that famotidine reduces the development of stomach ulcers by 90% and upper-intestinal ulcers by 95% compared to placebo. The study also showed fewer adverse events in the famotidine group.
Researchers at GUMC discovered a small molecule that prevents the fusion protein responsible for Ewing's sarcoma from binding to another protein, RNA helicase A. This novel approach could provide a model for designing treatment for other disorders caused by protein-protein interactions.
Soay sheep on Scotland's Hirta island have shrunk by 5% in size and body weight due to the warmer climate. The decline is attributed to increased competition for limited resources, resulting from a longer growing season and more surviving lambs.
A new study from Stanford University School of Medicine finds that hair sheep blood is a perfect substitute for horse or sheep blood in microbiology tests, reducing costs and improving diagnosis in the developing world. The researchers also discovered that collecting blood in donation bags eliminates the need for defibrination, making ...
Researchers used AdS/CFT correspondence in string theory to describe electrons' quantum-critical state, which plays a role in high-temperature superconductivity. The discovery bridges the gap between macroscopic and microscopic worlds.
A recent study of Mexican women's mental health found that those whose husbands work in the US experience a significant decline in well-being. The research, published in Health Care for Women International, compared the mental health of 47 'sending' and 47 'non-sending' wives.
A new study suggests that a changing form of El Niño could result in a greater number of hurricanes forming in the Atlantic Ocean. This 'El Niño Modoki' type forms in the Central Pacific, leading to increased storm frequency and potential for landfall along the Gulf coast and Central America.
Researchers at Duke University found that ferns diversified significantly during the Cretaceous period, when flowering plants dominated plant communities. Ferns adapted by developing the ability to live on light with a red spectrum and becoming epiphytes, thriving in tree canopies.
A study found that mental stress causes vasodilation in healthy subjects, resulting in a net increase in brain blood flow. However, individuals with high blood pressure showed no vasodilation or change in brain blood flow under similar conditions.
Researchers found a strong association between congenital brain defects and preterm birth in a study of over 1,000 infant autopsies. Brain malformations were significantly associated with preterm birth, with certain types of malformations having stronger associations than others.
Health professionals face challenges in addressing Indigenous health disparities due to colonization and globalization, according to Canadian researchers. Traditional healing practices, language retention, and self-determination are key factors in promoting well-being for Indigenous peoples.