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Science News Archive March 2011 - Page 19


Page 19 of 28

What's in a name? Broadening the biological lexicon to bolster translational research

Developmental biologist Hazel Sive proposes using the term 'tool' to define biological systems that don't accurately recapitulate human disorders, but provide valuable insights. These 'tools' can be used in loss-of-function studies and screening for chemicals that affect gene activity, potentially leading to therapeutic targets.

SourceWhitehead Institute for Biomedical Research·JournalDisease Models & Mechanisms·DateMar 9, 2011

Abnormal neural activity recorded from the deep brain of Parkinson's disease and dystonia patients

Abnormal neural activity was recorded from the deep brain of Parkinson's disease and dystonia patients, confirming previous animal study results. The findings suggest that cortically evoked neural responses in the basal ganglia can be used to determine target locations for deep brain stimulation electrodes.

SourceNational Institute for Physiological Sciences·JournalMovement Disorders·DateMar 9, 2011

New microscope decodes complex eye circuitry

Researchers have discovered that retinal ganglion cells receive visual information from amacrine cell dendrites running along the null-direction, allowing for directional selectivity. This mechanism relies on asymmetric synapses and inhibitory influences between neighbouring amacrine cells.

SourceMax-Planck-Gesellschaft·JournalNature·DateMar 9, 2011

Web-crawling the brain

A team of researchers at Harvard Medical School has developed a technique to unravel the complex neural circuits in the brain. By crawling through individual connections, they created a partial wiring diagram that revealed interesting insights into how the brain functions.

SourceHarvard Medical School·JournalNature·DateMar 9, 2011

'Singing' mice -- the ongoing debate of nature vs. nurture

Researchers have found that mice exhibit complex vocalizations with age, suggesting potential for vocal learning. However, a cross-fostering experiment suggests that mouse songs may be genetically determined. The debate over nature vs. nurture remains unresolved, highlighting the complexities of scientific research.

SourcePLOS·JournalPLOS ONE·DateMar 9, 2011

Novel method could improve the performance of proteins used therapeutically

Whitehead Institute scientists have developed a novel method using the enzyme sortase A to site-specifically modify proteins, increasing their potency, thermal stability, and metabolism. This technique can be applied to improve therapeutically important proteins such as interferon alpha 2 and granulocyte colony-stimulating factor 3.

SourceWhitehead Institute for Biomedical Research·JournalProceedings of the National Academy of Sciences·DateMar 9, 2011

A-ha! The neural mechanisms of insight

A new brain-imaging study has identified specific brain activity associated with 'A-ha!' moments, which may promote the formation of long-term memories. The researchers found that higher activity in the amygdala during insight moments predicted more successful performance in memory tasks.

SourceCell Press·JournalNeuron·DateMar 9, 2011

Missing DNA helps make us human

Researchers identified 510 missing genetic segments that distinguish humans from chimpanzees and other animals. These segments affect gene regulation, enabling traits like large brains and sensory whiskers. The study reveals how human evolution occurred through subtle DNA changes.

Baby stars born to 'napping' parents

Cardiff University astronomers propose that young stars' long naps could lead to the birth of smaller stars and planets. The researchers developed advanced computer models to simulate young star behavior, finding that disc fragmentation is possible in nature.

New study proves the brain has 3 layers of working memory

Researchers at Rice University and Georgia Tech found evidence for three distinct layers of working memory, including a core focusing on one active item and surrounding areas holding multiple items. Predictability can improve multitasking by automizing certain tasks, allowing individuals to effectively switch between tasks.

SourceRice University·JournalJournal of Cognitive Psychology·DateMar 9, 2011

Banana peels get a second life as water purifier

Researchers have discovered that minced banana peels can quickly and efficiently remove toxic metals like lead and copper from river water, outperforming other materials in the process. The discovery could provide a sustainable solution for water purification, especially in areas where access to clean drinking water is limited.

SourceAmerican Chemical Society·JournalIndustrial & Engineering Chemistry Research·DateMar 9, 2011

Missing DNA makes us human

The study found that humans have unique non-coding DNA segments missing in chimpanzees and other animals, which are correlated with specific human physical characteristics. These differences may have evolved to favor pair-bonding relationships and group living, rather than rapid copulation.

SourcePenn State·JournalNature·DateMar 9, 2011

Gene variant influences chronic kidney disease risk

Researchers identified a single genetic mutation in the CUBN gene linked to albuminuria, a condition indicating kidney disease, in both diabetic and non-diabetic individuals. The study's findings have significant implications for understanding the mechanisms behind kidney disease and potentially leading to novel treatment targets.

SourceJohns Hopkins Bloomberg School of Public Health·JournalJournal of the American Society of Nephrology·DateMar 9, 2011

Learning to see consciously

Researchers found that training improves subjective perception of stimuli, leading to conscious sight. The brain regions involved in learning effects differ from those for automatic stimulus processing, suggesting two distinct neural pathways.

SourceMax-Planck-Gesellschaft·JournalProceedings of the National Academy of Sciences·DateMar 9, 2011

How do we combine faces and voices?

A new study has revealed the brain networks involved in person recognition using both face and voice information. The research found that specific regions of the left angular gyrus and right hippocampus are activated when recognizing people from combined visual and auditory cues.

SourceElsevier·JournalCortex·DateMar 9, 2011