A team of scientists identified 7 compounds that show new effects against HIV-1, Zika virus, and Rift Valley Fever, expanding the available therapeutics for viral disease treatment. The researchers believe these broad-spectrum antiviral drugs could save resources and time needed for development of novel drugs.
Researchers have found that adding nanowires to solid-state electrolytes can increase conductivity, reduce stress, and prevent fires in lithium-ion batteries. The addition of nanowires also improves the battery's rate performance and cyclic capacity, making it a safer alternative.
Researchers found targeting telomerase and inhibiting mitochondrial function synergistically killed NRAS-mutant melanoma cells, inducing extensive cell death and DNA damage. Combination therapy also improved survival in a mouse model.
A Northwestern University research team has developed a new semiconductor device that can detect gamma rays and identify radioactive isotopes at room temperature. The device, made of cesium lead bromide, offers high spectral resolution and can be scaled up for widespread use in biomedical imaging, astronomy, and spectroscopy.
Mattershift, a UConn-backed startup, has developed carbon nanotube technology for mass-producing carbon-zero fuels, fertilizers, and pharmaceuticals. The company aims to remove CO2 from the air and convert it into usable fuels at a lower cost than fossil fuels.
A new study shows that sunlight transforms oil into different compounds that dispersants cannot easily break up, reducing their effectiveness by at least 30 percent. The findings suggest that responders should factor in sunlight when determining the window of opportunity to use dispersants effectively.
Researchers identify new position of mitochondria by analyzing environmental sequencing data and reconstructed genomes of alphaproteobacteria. The findings suggest that mitochondria evolved from an ancestor that later gave rise to all recognized Alphaproteobacteria groups, contradicting previous theories.
Researchers at the University of California - Berkeley have discovered the molecular structure of human telomerase, a key enzyme in aging and cancer. The detailed picture reveals possible drug-target sites, allowing for more targeted treatments to be developed.
A new study finds that a hospital-based addiction medicine team significantly reduces burnout and frustration among healthcare providers, while improving patient engagement and care. The team's approach fundamentally reframes substance use disorder as a treatable chronic disease.
A study by University at Buffalo researchers found that drug-filled 3D printed dentures can reduce fungal growth in the mouth. The innovative technology uses microscopic capsules to release Amphotericin B, an antifungal medication, which can help prevent infection while dentures are in use.
The study found that having a less cohesive personal network in high school makes students more open to new relationships at university. Students who were more rooted in their hometowns experienced difficulties adapting to university life and relied on maintaining weak contact with old schoolmates through digital media.
A portable test has been developed to identify populations at risk of measles and rubella infections in remote areas. The new technology can rapidly test multiple blood samples and is a potentially useful tool for addressing vaccine-preventable diseases in developing countries.
Scientists found that brief sleep arousals are triggered by wake-promoting neurons' electrical noise, which is affected by body temperature. Higher temperatures may lead to fewer and shorter arousals, potentially increasing the risk of Sudden Infant Death Syndrome (SIDS).
A team of researchers from the University of Toronto has developed a portable, reconfigurable lab-on-a-chip diagnostic platform that can gauge immunity to vaccine-preventable diseases among vulnerable populations. The platform was validated at a refugee camp in Kenya and showed promising results in detecting measles and rubella.
Researchers discovered that subplate neurons form transient synapses with newborn neurons, controlling their migration during fetal brain development. This finding sheds light on the mechanisms regulating neuronal migration and its implications for mental disorders such as autism and schizophrenia.
Young Canadian men prioritize selflessness, openness, and health, marking a shift from traditional masculine values. The study found that 91% of participants believed a man should help others, while 88% valued being open to new ideas.
Astronomers have observed a gargantuan cosmic collision of 14 young galaxies, poised to merge and form a colossal galaxy cluster. This protocluster is located 12.4 billion light-years away, offering an unprecedented opportunity to study the early stages of cluster formation.
Researchers at Aalto University have successfully generated and detected entanglement in massive mechanical oscillators, opening doors for new quantum technologies. The achievement uses a theoretical innovation developed by Dr. Matt Woolley and Prof. Aashish Clerk to stabilize exotic quantum states.
Researchers linked cognitive function levels to crash risk in older drivers without dementia, finding lower cognitive function increases the risk of motor vehicle crashes. Depression also increased the risk for these drivers.
Researchers found interdependent behaviors in customers from rice-growing regions and individualistic behaviors in those from wheat-growing regions. Historical farming legacies play a significant role in shaping everyday behavior, contradicting the idea that wealthier cultures become more individualistic.
A recent study of almost 100,000 school children has found that children born to teenage mothers have the highest risk of developmental vulnerabilities at age 5. The risk declines with every additional year of a mother's age up to 30 years before increasing slightly after 35 years and older.
Researchers at UCSB are developing a chip that uses ionic memristor technology to create a physically unclonable device, rendering it vulnerable to cyber attacks. The technology aims to prevent cloning and hijacking of devices in networks, making them ideal for securing IoT devices.
The Society for Cardiovascular Angiography and Interventions (SCAI) has released new guidelines for selecting specific categories of devices in endovascular therapy. The guidelines provide device-focused recommendations based on a review of comparative effectiveness data, including safety and efficacy of femoral-popliteal devices.
Research reveals deletion of adipose oxidative stress decreases lipid accumulation in the liver, improving insulin resistance and inducing metabolically healthy obesity. Oxidative stress suppresses lipogenic genes in adipocytes, leading to de novo lipogenesis suppression.
Researchers found temperature, precipitation, humidity, and cloud cover associated with positive or negative expressed sentiments. Positive expressions increased up to 20 degrees Celsius before declining over 30 degrees Celsius, while high humidity and cloud cover were linked to negative expressions.
Sea-level rise and wave-driven flooding will make freshwater resources non-potable, threatening human populations on low-lying atoll islands. The tipping point for unavailability of potable groundwater is projected to be reached by the middle of the 21st century.
A new implantable device could help insulin-producing cells live longer after transplant and improve treatment of type 1 diabetes. The device, developed by MIT researchers, supplies oxygen to transplanted islet cells, allowing them to remain viable for several months and maintain normal blood glucose levels.
A well-preserved horse burial at Tombos has provided new insights into the social significance of equids in the Nile Valley during the Third Intermediate Period. The discovery suggests that horses represented symbols of a larger social, political and economic movement in ancient Nubian culture.
Bayou, developed by Rice University, uses neural sketch learning to recognize patterns in Java code and generate code snippets. This enables developers to get immediate feedback on their queries, making it easier to navigate the numerous APIs.
A recent study found that maternal binge drinking during pregnancy and lactation can impair the mental health of their offspring, leading to mood disturbances and increased vulnerability to alcohol abuse as adolescents. The research suggests that even occasional heavy drinking can have a depressive effect on the mother and pass on chan...
A new 3D printing technique allows for the direct printing of electronics on human skin, with potential applications in military technology and medical treatments for skin disorders. The printer uses computer vision to adjust to small movements of the body during printing and can be used to print temporary sensors or solar cells.
Researchers discovered that mature ependymal cells require continuous Foxj1 production to maintain shape and function, but viruses can shut down this process, leading to hydrocephalus. This study may lead to alternative treatments for the condition.
A study of 704 day surgery patients in Sweden found that those with inadequate health literacy had poorer postoperative recovery and reduced health-related quality of life two weeks after surgery. Identifying patients with low health literacy is crucial to optimize their care and improve outcomes.
A new $1.9 million grant will help researchers discover ways to prevent Necrotizing Enterocolitis (NEC) in premature infants, a deadly disease affecting thousands annually. The study aims to create the first predictive test for NEC using fecal bile acid levels and intestinal microbiome analysis.
According to Philip Cook's analysis, gun thefts represent only about one percent of all gun transactions in the US. In Chicago, only a tiny proportion of crime guns were ever reported stolen to the Police Department.
A new natural gas catalyst aims to reduce methane emissions from vehicle exhaust, a potent greenhouse gas. The US Department of Energy-funded project will develop and optimize a lower-cost, more efficient catalyst to eliminate unreacted methane, making natural gas a cleaner-burning fuel option.
The study demonstrates the efficacy of a single dose of NDV-3A in reducing recurrences of vaginitis in patients with RVVC, with younger patients showing higher efficacy rates. The vaccine also generates rapid and robust immune responses.
A Brazilian research team has developed a novel technique to produce high-performance silver nanoparticles with 32 times the bactericidal capacity of existing materials. The new method uses pulsed laser irradiation and reduces production costs, making it economically feasible for large-scale applications.
Medical College of Georgia scientists found that drinking baking soda encourages the spleen to promote an anti-inflammatory environment, reducing destructive inflammation in autoimmune diseases. This shift was observed in rats and healthy people, with a reduction in pro-inflammatory cells and an increase in anti-inflammatory macrophages.
Eight out of ten transformative medicines in the US between 1985 and 2009 originated from fundamental discoveries, with an average time to approval of 30 years. Curiosity-driven science is essential for discovering new medicines.
A study found that media coverage on cancer rarely addresses the importance of age as a risk factor, resulting in under-representation of older adults. This can lead to a lack of awareness, delayed detection, and poorer outcomes for this population.
Researchers at Nara Institute of Science and Technology have developed the world's smallest wireless optical biodevice, measuring just 1 mm³ and 2.3 mg in volume and weight. The device converts infrared light into blue light to control neural activity, offering a promising solution for optogenetics applications.
Researchers found that changing water temperature and algal blooms affected sea urchin populations, leading to abnormal development of their larvae. The study provides valuable insights into the importance of long-term monitoring for detecting ecological changes and understanding their causes.
Researchers found that regular mid-day naps improve neurocognitive function and daytime attention in adolescents. The ideal nap duration is between 30-60 minutes, and routine napping is associated with better nighttime sleep quality.
Researchers at Argonne National Laboratory found that nuclear power plants can adjust to changing demand for power, enabling the use of more renewable energy. This flexibility can lower electricity costs for consumers and reduce greenhouse gas emissions.
The University of Colorado Anschutz Medical Campus has received a $46.5 million NIH grant to enhance its translational science workforce and research environment. The grant will support the development of novel methodologies and resources to tackle rare diseases, improve health screenings in underserved communities, and reduce mortalit...
Researchers traced Twitter tweets using the word 'shithole' to identify who engages in stigmatizing discourse and how places are stereotyped. The study found that men and women experience living in a place differently, with 38% of tweets maligning their own hometown.
Researchers created a tiny electro-optic modulator that translates electrical signals into light at speeds 10s of times faster than current technologies. The device uses plasmonics and has the potential to integrate photonics and electronics on a single chip, revolutionizing information technology.
Researchers simulated conditions inside a planet three times larger than Earth using high-powered laser beams. The study revealed that the crystal structure of iron-silicon alloys changes with higher silicon content under extreme pressures, providing new insights into the nature of super-Earths and their cores.
Advances in genetic testing have improved insights for parents of children with epileptic encephalopathy (EE), a rare and serious form of epilepsy. The study found that 10% of parents have mosaicism, which may also apply to other disorders like autism and intellectual disability.
Researchers developed a new method for early and accurate breast cancer screening using electronic nose gas sensors and GC-MS analysis, achieving 95% average accuracy in detecting breast cancer biomarkers from breath samples. Urine samples also yielded 85% average accuracy with this technology.
A survey found that over 40% of people in England believe stress, food additives, and electromagnetic frequencies cause cancer despite a lack of scientific evidence. Those with better knowledge of proven cancer causes were more likely to make healthier lifestyle choices.
A recent study published in Frontiers in Nutrition found that a Mediterranean-type diet enhances the good bacteria living in the gut, increasing diversity by up to 7% compared to a Western diet. The study used an animal model and analyzed fecal samples to confirm these findings.
The James Webb Space Telescope has the potential to observe the first stars in the universe, which formed about 200-400 million years after the Big Bang. The telescope can capture light from single stars with a massive amount of gravitational lensing, amplifying it up to 10,000 times.
Researchers discovered that bacteria and fungus working together make biofilm on teeth more pathogenic and difficult to remove. A combination of fluconazole and povidone iodide effectively treats the biofilm by disrupting the protective matrix produced by bacteria.
The Society for Cardiovascular Angiography and Interventions has updated its consensus guidelines to allow for flexibility in length of stay after percutaneous coronary intervention (PCI), prioritizing patient-centered care. The new guidelines assess readiness for discharge along three lines: procedural, patient, and programmatic factors.
A study found that changes in brain networks can predict psychosis in high-risk patients. Cortical folding was analyzed to identify potential biomarkers for clinical diagnosis.
Researchers found a significant link between exposure to blue light at night and higher risks of developing breast and prostate cancer. The study used images taken by astronauts to evaluate outdoor lighting in Madrid and Barcelona.
A University of Cincinnati geology student, Andrew Gangidine, is developing a marker for ancient bacterial life on Mars to aid NASA's search. He's studying microbial life in silica hot springs at Yellowstone National Park to create a useful indicator of life on the red planet.
A study by University of Turku researchers found that retirement transition leads to a significant increase in sitting during free time, averaging six hours per day. This increase was especially noted among women and individuals with pre-existing health conditions.