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Science News Archive October 2020 - Page 13


Page 13 of 47

Clinical trial shows experimental drug safely slows progression of diabetic kidney disease

A clinical trial published in the New England Journal of Medicine shows that finerenone significantly slows the progression of diabetic kidney disease by 18% compared to a placebo. The study also found a reduction in cardiovascular event rates, offering new treatment options for patients with chronic kidney disease and type 2 diabetes.

SourceUniversity of Chicago Medical Center·JournalNew England Journal of Medicine·DateOct 23, 2020

New therapeutic approach against leukemia

Researchers have found a new way to make leukemic stem cells vulnerable by specifically dislodging them from their niches, allowing for potential treatment against chronic myeloid leukemia. The approach uses an RNA molecule complex to prevent the cancer stem cell's retention in its tumor-supporting niche.

SourceMax-Planck-Gesellschaft·JournalProceedings of the National Academy of Sciences·DateOct 23, 2020

Chemists develop framework to enable efficient synthesis of 'information-dense' molecules

A team of chemists from Scripps Research developed a theoretical approach that can ease the process of making highly complex, compact molecules. They used information theory and computer modeling to analyze the synthesis of bilobalide, a molecule with strong promise as a potential neurological or psychiatric drug.

SourceScripps Research Institute·JournalJournal of the American Chemical Society·DateOct 23, 2020

Plant compound reduces cognitive deficits in mouse model of Down syndrome

Researchers found that apigenin improved cognitive and memory deficits in mice with Down syndrome-like characteristics, reducing inflammation and increasing brain growth. This study raises the possibility of a prenatal treatment to lessen cognitive deficits in fetuses diagnosed with Down syndrome through prenatal testing.

Mathematical modeling suggests optimal timing for antiviral therapies against COVID-19

A new study by Ashish Goyal and colleagues proposes that treating with potent antiviral therapy before peak viral load can effectively suppress viral AUC, reducing the duration of viral shedding. The model also suggests that timing is crucial in determining the effectiveness of different therapies against COVID-19.

Where will the seabirds go?

A 14,000-year peat record reveals an ecosystem shift after seabird establishment 5,000 years ago, driven by guano-derived nutrients. This study highlights the critical role of seabirds in terrestrial ecosystems and warns of potential consequences for their survival in a warming climate.

SourceLehigh University·JournalScience Advances·DateOct 23, 2020

Super-resolution microscopy and machine learning shed new light on fossil pollen grains

Researchers developed a new method to identify fossil pollen using super-resolution microscopy and machine learning, allowing for the classification of previously unknown legume groups. The trained models achieved 90.3% accuracy in identifying samples from ancient Africa and South America.

SourceUniversity of Illinois College of Liberal Arts & Sciences·JournalProceedings of the National Academy of Sciences·DateOct 23, 2020

Poor women in Bangladesh reluctant to use healthcare

A new study published in PLOS ONE found that poor women in Dhaka slums are unwilling to give birth at maternal facilities due to fears of undocumented payments, lack of support and cultural perceptions. The study highlights the importance of providing pregnant women with information to break free from these fears.

SourceFlinders University·JournalPLOS ONE·DateOct 23, 2020

Reviewing multiferroics for future, low-energy data storage

A new UNSW study comprehensively reviews the magnetic structure of bismuth ferrite (BiFeO3), a multiferroic material that displays both magnetic and electronic ordering at room temperature. This unique property allows for low-energy switching in data storage devices, making it a promising material for future, low-energy data storage.

New tool can diagnose strokes with a smartphone

Researchers have developed a machine learning model that analyzes speech and facial movements to diagnose strokes with high accuracy, potentially saving valuable time in diagnosing the condition. The tool was tested on over 80 patients and achieved 79% accuracy comparable to clinical diagnostics by emergency room doctors.

Antiretroviral therapy can't completely stop accelerated cell aging seen in HIV

A new study by UCLA researchers found that antiretroviral therapy given over two years was unable to completely restore age-appropriate epigenetic patterns in HIV-infected adults. This suggests that even successfully treated HIV-infected individuals are at an increased risk for early development of diseases commonly associated with aging.