A bioethicist contends that crisis-care protocols should ignore patients' age, proposing instead a patient-specific values approach. She suggests using a Clinical Frailty Scale to predict near-term survival and considers a lottery as the fairest way to prioritize individuals under dire conditions.
A systematic review and meta-analysis of 81 studies found that COVID-19 patients with cancer had a higher risk of death compared to those without cancer. Younger age, lung, and hematologic cancers were identified as risk factors for poor outcomes from COVID-19
A new paper highlights the need for uniform patient confidentiality policies for adolescents, as state laws vary significantly and often contradict medical societies' standards. The authors argue that this variability can lead to clinically significant consequences for adolescents seeking care for sensitive issues.
Scientists have detected an increase in atmospheric helium levels, which is attributed to the release of helium as a by-product of fossil fuel combustion and extraction. This finding has significant implications for understanding industrial activity and the potential uses of rare helium isotopes.
Researchers found that extinct species had smaller brains than surviving ones, suggesting a link between brain size and adaptability. The study suggests that larger brains helped extant species cope with human activities and climate change.
Researchers found that greater mouse-eared bats imitate the buzzing sound of a stinging insect to avoid predatory owls. The study, published in Current Biology, provides evidence of interspecific mimicry between mammals and insects.
Chronobiologists have identified a crucial mechanism involved in the setting of the circadian clock of cyanobacteria, a model organism for studying circadian systems. The study reveals that the KaiC protein's dual ATPase active sites communicate through an interface to regulate the assembly and disassembly cycle of other clock proteins.
Researchers found that invoking science in marketing pleasurable products like cookies decreases consumer interest. However, pairing science with practicality makes sense to consumers. The study suggests updating public beliefs about scientists and their approach to make science more acceptable for marketing indulgent goods.
A multicentre study has proven personal construct therapy as effective as cognitive-behavioural therapy in improving quality of life and symptoms of depression in patients with fibromyalgia. The therapy focused on people's identity and how they see themselves, offering a personalized approach to treatment.
Benjamin Gatling plans to conduct a survey and inventory of the materials, train in best practices, and purchase equipment. The project aims to preserve and digitize the complete collection, offering a unique window into Soviet Central Asia's cultural patrimony.
Researchers found phosphatidylinositol bisphosphate (PIP2) essential for epithelial cell-cell adhesion and maintaining cellular identity. PIP2 regulates epithelial properties by recruiting Par3 to the plasma membrane, facilitating the formation of adherens junctions and preventing epithelial-mesenchymal transformation.
A new study found that a personalized text messaging support program improved lifestyle measures among heart attack survivors, including exercise habits and cholesterol levels. However, the program had no significant impact on medication adherence.
Research finds that COVID-19 led to a significant decrease in racial inequities in primary care appointments, with Black patients' visit completion rates increasing by 7-8% in the second half of 2020. Telemedicine adoption played a key role in closing this gap.
A new volcanic modeling study found that ice-capped volcanoes like Westdahl Peak are delayed in eruption by approximately seven years due to the added pressure from glacial ice. This increase in time may seem insignificant on a geologic scale, but it's significant on the human time scale.
A recent study found significant racial and ethnic disparities in excess deaths from external causes, including homicide, suicide, and transportation accidents. The study estimated these disparities during the COVID-19 pandemic, highlighting the need for targeted interventions to address health inequities.
A new study by Weill Cornell Medicine investigators found that T cells' genetic program and developmental path affect their response to immunotherapy. The results suggest that infiltrating T cells don't all meet the same fate in every tumor, with long-lived memory programs correlating strongly with overall survival
A new study from McGill University finds that people living near regions prone to wildfires may have a higher incidence of lung cancer and brain tumors. Exposure to carcinogenic wildfire pollutants on a chronic basis increases the risk of certain cancers, according to researchers.
Researchers at H. Lee Moffitt Cancer Center & Research Institute have identified key factors impacting the effectiveness of adaptive therapy in cancer treatment. The study found that spatial organization and competition between drug-resistant cells play a crucial role in determining the success of adaptive therapy.
Heads of State and Government meeting at the United Nations' global conference on land called for immediate action to stem life and livelihood losses due to desertification, land degradation, and drought. The Abidjan Call urges prioritizing drought relief and committing to achieving land degradation neutrality by 2030.
The university's new Robotics and Autonomous Systems Teaching and Innovation Center (RASTIC) will provide students with hands-on experience in robotics, autonomous systems, and self-driving technology. The lab aims to boost Massachusetts' competitiveness in the tech sector by supporting innovative projects and startups.
Physicists from Cracow have developed a new measurement technique to track phenomena lasting attoseconds, using X-ray chronoscopy. This approach potentially makes it possible to infer events in the world of attophysics even at current XFEL technology.
The cosmic time synchronizer uses cosmic rays from deep space to detect specific signatures, allowing devices to synchronize their clocks accurately. This technology has the potential to fill gaps in current time synchronization methods, particularly in remote or underwater locations.
The pandemic has led to increased adoption of virtual meeting platforms like Zoom, affecting team trust and knowledge sharing. This can result in time and cost over-runs or negatively impact work quality.
A new study by the University of South Australia found that up to a quarter of people aged over 50 with undiagnosed visual problems like cataracts or AMD are misdiagnosed with mild cognitive impairment. Cognitive tests relying on vision-dependent tasks can skew results.
Researchers assessed modifiable risk factors for Alzheimer disease and related dementias in the US population, finding significant differences by sex, race, and ethnicity. The study highlights the importance of addressing these disparities to prevent cognitive decline.
A recent study in CMAJ found that nearly half of Canadian drownings were caused by pre-existing medical conditions, with seizure disorders posing a significant risk. Young women aged 20-34 with seizure disorders were particularly vulnerable, facing a risk 23 times higher than the general population.
Researchers have discovered 'proto-peat', a thin layer of organic matter containing high levels of carbon, in the Arctic. This finding suggests new carbon sinks may be forming as the region warms up.
The May issue of the CHEST journal features 56 articles on clinically relevant topics such as asthma, COPD, and critical care. The journal also includes a special Adult Cystic Fibrosis Series with latest epidemiologic data and challenges in managing CF.
Researchers compiled catalog of Lake Erie-area earthquakes between 2013 and 2020 to investigate potential connection to shifting water levels. The study found no conclusive correlation between earthquake rates and water levels.
A new online tool, HazardAware, provides disaster readiness reports for 13.3 million addresses in 196 counties along the Gulf of Mexico, including all of Florida. The tool assesses a property's resilience to hazards such as hurricanes and flooding, and offers customized mitigation information to reduce future hazard loss.
Researchers at Oak Ridge National Laboratory developed an algorithm that guides breakthroughs in new materials using self-driving microscopes. The approach combines physics and machine learning to automate microscopy experiments, enabling faster discoveries of functional materials' properties.
Researchers developed a new test method to detect tuberculosis (TB) progression from latent infection in elephants using IgG antibodies against Antigen 85B. High levels of IgG against ESAT6/CFP10 remained constant, while IgG against Ag85B increased before disease onset and declined with treatment.
A seven-year research project suggests that a short chain of amino acids, the HTL-001 peptide, is effective at targeting and inhibiting Hox genes responsible for GBM growth. The study offers hope for finding a solution to this devastating form of brain cancer.
Researchers developed nanoparticles with a changeable net charge that facilitates intratumor accumulation and penetration, achieving 32.1% of injected dose/g of tissue. This study suggests using the changeable net charge as a promising strategy for tumor-targeted delivery based on the EPR effect.
A new study reveals that future super cyclones will disproportionately affect populations in South Asia, particularly India, with increased exposure to extreme flooding. If greenhouse gas emissions continue at current levels, over 250% of India's population may experience flooding exceeding 1 meter by 2050.
The electrochemistry designette is a pedagogical tool that enables instructors to visualize students' competence and misconceptions on electrochemical principles. Developed by SUTD researchers, the designette has proven highly effective in allowing instructors to spot misconceptions and provide prompt intervention.
The study identifies two subpopulations of liver ILC1s, Ly49E+ and Ly49E-, with distinct origins and functions. The Ly49E+ subset is produced by embryonic hematopoietic precursors and exhibits stronger cytotoxicity, while the Ly49E- subset has stronger immune memory potential.
Researchers have discovered a way to suppress a specific protein that promotes resistance to drugs commonly used to treat AML patients. This breakthrough has the potential to revolutionize treatment and prolong survival for those affected by the disease.
Researchers have developed advanced optical 3D printing methods for creating tissue scaffolds with controlled structure and scale, mimicking native extracellular matrices. These methods offer high precision, cost-effectiveness, and potential for broader applications in tissue engineering.
A novel SURF4-to-proteoglycan relay mechanism regulates the secretion of sonic hedgehog (Shh), a key signaling molecule in cancer progression. The study offers new insights into inhibiting Shh secretion and shutting down the Hh signaling pathway to hinder cancer progression.
Intelligent metasurfaces have three crucial properties: digitalization, programmability, and intelligence. They enable control without human intervention, unlocking devices like cloaking, tunneling, and holograms.
Researchers are developing a project to improve team cognition for future space missions. The project will examine how decreases in cognition cascade to the team level and impact performance. It aims to develop training and technologies, such as AI-based assistants, to counteract potential decreases in team performance.
A team of scientists has discovered a bi-directional neural network connecting the legs and visual system in fruit flies, enabling them to walk while tracking their steps. The study reveals that this network supports walking on two different timescales simultaneously.
A new study maps the distinct differences among cells in the retina's retinal pigment epithelium (RPE), which nourishes and supports photoreceptors. The research identifies five subpopulations with varying levels of disease sensitivity, opening doors to more precise cell and gene therapies for specific degenerative eye diseases.
A new white paper from Portland State University explores how purchase incentive programs can expand the current e-bike market, identifying effective program structures and administration methods. The study examines impacts and statistics from around 75 e-bike incentive programs in North America.
Researchers at the University of Cambridge have identified a new mechanism that appears to reverse the build-up of aggregates in neurodegenerative diseases, such as Alzheimer's and Parkinson's. By stressing cells, they found that protein misfolding was eliminated, potentially allowing for the refolding of correctly folded proteins.
A statewide CHAMPS program in Mississippi increased breastfeeding rates among birthing women and reduced racial disparities. The program reached 98% of eligible patients, resulting in a 10-point increase in breastfeeding initiation rates.
Researchers discovered fossilized trilobite appendages exhibiting characteristics similar to those found in male horseshoe crabs. These findings suggest a unique mating strategy, where males use the appendages to grasp females during reproduction, providing insight into the reproductive behavior of ancient complex animals.
The study reveals that superconductors can transmit spin currents between magnets, allowing for controlled magnetic interactions and modifying the magnetic response. This breakthrough enables new approaches to information processing using magnetic materials at low temperatures.
The NIH has launched a Phase 1 clinical trial to evaluate an investigational preventative vaccine for Epstein-Barr virus (EBV). The study aims to assess the safety and immune response of the EBV gp350-Ferritin nanoparticle vaccine with a saponin-based Matrix-M adjuvant.
A new lensless opto-electronic neural network (LOEN) architecture is developed for computer vision tasks, utilizing a passive mask to perform convolution operations in the optical field. The system achieves high recognition accuracy and energy efficiency compared to traditional machine vision links.
A University of Washington model found that the body's ability to create cloned immune cells falls significantly with age, leading to increased susceptibility to COVID-19 in the elderly. The study suggests that genetic limits on cell division may play a role in the devastating effects of COVID-19 on older adults.
A new project led by INRS will assess how living organisms respond to reduced pesticide use, focusing on soil and water health. The study aims to provide a clear understanding of the benefits and limitations of reducing pesticide use in sustainable farming.
A new study by George Mason University Professor Priyanka Anand found that paid leave mandates reduce the likelihood of caregivers reducing their paid work hours to care for a spouse with a disability or health shock. However, without job protection, these policies may lead to increased employment departure among caregivers.
A new study by New York University's Center for Social Media and Politics found that labeling credible sources does not shift people away from low-quality information or reduce misperceptions. However, providing credibility indicators may improve the news diet quality of heavy misinformation consumers.
A UCI-led study shows that the global trade of agricultural goods is driving a growth in greenhouse gas emissions in less-developed nations, with land-use change contributing three-quarters of these emissions. The study highlights the need for importers to adopt 'buy clean' policies and for regions to improve supply chain transparency.
Researchers have discovered a simple way to prevent pharmaceutical fraud using candy-coated pills with unique color patterns. The technique, called CandyCode, uses tiny multicolored candy nonpareils as a uniquely identifiable coating for pharmaceutical capsules and pills.
A new photonic-engineered thermal management strategy incorporates enhanced color-preserving radiative cooling into existing enclosures, reducing energy consumption by up to 63%. The system is designed to simultaneously reflect solar energy and radiate infrared energy, while blocking heat radiation from entering the inner space.
Researchers at UT Southwestern discovered that timing feedings to match the active period of the circadian cycle extended the life span of lab mice more than three times as much as caloric restriction alone. The findings showed improved metabolic health, lower inflammation and cancer incidence in long-lived animals.
A six-month coaching program for female resident physicians significantly reduced emotional exhaustion and imposter syndrome, while increasing self-compassion. The program addressed toxic physician culture and provided tools to manage thoughts, feelings, and actions.