A new study reveals IL-6 plays a crucial role in regulating neuroinflammation and protecting the nigrostriatal pathway in Parkinson's disease. The research found that restoring IL-6 levels can reverse aggravated pathology and partially ameliorate motor dysfunction in mice.
Researchers developed a physics-informed neural network approach to predict material properties and optimize controlled-release systems. The new method requires significantly less data than traditional AI models, slashing development time for patches, bandages, and implants.
Researchers developed SST-MedChain, a patient-centric framework for secure electronic medical record sharing on permissioned blockchains. The system uses non-interactive delegation, one-time access tokens, and policy-bounded re-delegation to reduce costly on-chain authorization while preserving traceability and revocation.
Researchers have identified high rates of overweight/obesity (82%) and hypertension (higher than statewide average) in Franklin Parish, with income levels linked to lower hypertension rates. Older residents are also more likely to have undiagnosed high cholesterol and diabetes.
Researchers from Tohoku University and IIT Indore developed a sulfide-templated Cu nanocluster that selectively produces methanol from CO₂ under mild conditions. This breakthrough enables precise modulation of the copper valence state in nanoclusters, unlocking cleaner and more efficient pathways for converting CO₂ into valuable fuels.
Researchers are designing molecules that mimic natural sugar structures to block viral binding proteins, preventing cell infection. Broadly effective therapies against multiple viruses, including influenza and coronaviruses, aim to be developed using this innovative platform.
A new AI model predicts job salaries with high accuracy by identifying key skill combinations that significantly impact compensation. The model offers transparent salary predictions, revealing the monetary value of specific skills, and provides market insights on skill premiums across industries.
Researchers at TU Wien have developed a new practical method to estimate the actual expected lifetime of electronic components using novel materials. This approach allows for reliable and rapid lifetime prediction, helping industry identify the right materials and manufacturing techniques more quickly and with greater confidence.
Research from the University of Georgia found that adverse childhood experiences can negatively impact romantic relationships, leading to lower relationship satisfaction. Couples who struggle with everyday interactions and communication may be more likely to experience depression, anxiety, and loneliness in adulthood.
Researchers from Tohoku University developed a molecularly designed COF-graphene interlayer to mitigate polysulfide shuttling in Li-S batteries. The TUS-44@G layer delivered high reversible capacity, excellent rate capability, and long-term durability.
A comprehensive systematic review clarifies life expectancy across rare progeria disorders, revealing striking differences among subtypes. The analysis demonstrates that patients with Hutchinson-Gilford progeria syndrome have a median survival of 16 years, while those with mandibuloacral dysplasia type B have a median survival of 37 ye...
Research on Malaysia's Shah Alam Expressway found that accidents cluster at specific locations, particularly toll plaza areas and interchanges, and that vehicle type is a critical factor in determining crash severity. The study recommends targeted engineering improvements and vehicle-specific safety policies to address these issues.
The study reveals that early-age concrete's reduction in strength originates from the irreversible loss of cohesive strength, while frictional effects become dominant as damage develops. This new experimental method separates cohesive and frictional contributions, providing a clearer way to understand early-age concrete's behavior.
The American Journal of Occupational Therapy (AJOT) will move to the Sage Journals digital platform, strengthening reader experience and expanding visibility of occupational therapy scholarship. AJOT's mission remains unchanged, publishing peer-reviewed research supporting practitioners, educators, students, and researchers.
Researchers developed a new method to prepare pseudopregnant mouse recipients by utilizing nonestrous female mice. This approach minimizes the number of stock animals needed, optimizing facility space and supporting the 3Rs principles in laboratory animal care.
Ferroelectric memristors overcome computing hardware bottlenecks by processing data directly where it's stored. This enables significant reductions in data transfer overhead and improvements in computing efficiency.
Researchers at Ann & Robert H. Lurie Children's Hospital of Chicago identified a subtype of eosinophilic esophagitis associated with hypermobile joints and autonomic symptoms, including chronic light-headedness. Simple treatments for these symptoms can significantly improve quality of life in affected children.
Researchers have developed micro-flowers that focus applied magnetic fields into central regions, increasing local field strength and enabling imaging of previously inaccessible systems. This innovation expands the range of applications for nanoscale magnetic microscopy, including spintronics and nanometric materials.
Researchers developed an AI test to predict breast cancer recurrence, which outperformed existing genomic tests in accuracy and speed. The multi-modal AI test uses pathology slides and clinical data to estimate the likelihood of return, offering a potential solution for faster and less costly predictions.
The Retailers Creating a Responsible Environment (Retailers CARE) program aims to incentivize retailers to reduce promotion of harmful products by offering financial incentives. Participating retailers can earn rewards for meeting standards aimed at reducing youth access and limiting aggressive advertising.
Researchers have developed a fully automated framework that detects GPS flex power boosts with near-perfect accuracy and maps their geographic centers. The framework, combining detection and autonomous center-fitting systems, replaces slow manual methods and enables real-time monitoring and automated spatial mapping.
The FENS Forum 2026 is a premier meeting point for neuroscience researchers, covering molecular mechanisms to systems neuroscience, cognition, and translational research. The conference highlights key advances in brain tumours, speech processing, and brain mapping technologies.
BetaDescribe, an AI system, converts protein sequences into detailed textual descriptions of their functions and characteristics. The technology helps bridge the gap between characterized and existing proteins in nature, enabling researchers to rapidly generate evidence-based hypotheses regarding unknown proteins.
A new Virginia Tech study finds that patterns of repetitive negative thinking can carry anxiety into deeper distress among dementia caregivers, but also suggests that mindfulness training may help identify and interrupt this progression. Researchers also found that introducing mindfulness early on can aid in managing stress before it d...
Masahiro Tatsumisago received the NIMS Award 2026 for his pioneering research on amorphous and metastable crystalline materials with high ionic conductivity. His work has established a unified design principle for high ionic conductivity, laying the foundation for practical applications in all-solid-state batteries.
A research team from Tohoku University successfully controlled the spiral handedness of a metallic helimagnet using spin-polarized neutron scattering. This breakthrough enables ultra-high-density storage by utilizing the material's chirality to represent binary data.
The equatorial electrojet's spatial and temporal evolution is essential to understand its impact on space weather. Mid- and high-latitude forcing can rapidly alter or reverse the electrojet's direction, creating a westward counter-electrojet.
A study revealed persistent disparities in cancer care for LGBTQ+ populations, particularly transgender individuals, who face significant challenges accessing breast and cervical cancer screenings. The research highlights the urgent need for targeted interventions to bridge these gaps and ensure equitable care.
Researchers from the University of Osaka found that antagonistic ties play a crucial role in shaping social maps in the brain, which are also reflected in patterns of brain activity. This study sheds light on how our brains organize complex relationships and rivalries.
The Super-Kamiokande observatory has detected an indication of the Diffuse Supernova Neutrino Background (DSNB), a flux of neutrinos from many different supernovae over time. This breakthrough achievement provides a crucial clue for understanding the history of cosmic star formation and nucleosynthesis.
A non-canonical mTOR–SGK1 pathway regulates neuronal necroptosis, and targeting this axis halts necroptosis and neuroinflammation in traumatic brain injury. S6K1 inhibitors alleviate trauma-induced neuroinflammation and functional deficits.
The research shows that meaningful emission reductions are possible in small-vessel decarbonization, but the best option depends on context. Electrification performs best on short, predictable routes with low-carbon electricity and adequate charging infrastructure.
A new study found that AI-generated lunar crater catalogs often perform poorly when evaluated using human-defined scientific standards. The research highlights the need for standardizing benchmarks and transparent reporting to ensure the accuracy of AI-generated data.
A new study found that BCG vaccines can modify Alzheimer's biomarkers in non-Alzheimer's participants, suggesting a potential biological explanation for the observed link between BCG vaccination and lower disease risk. The vaccine also promoted increased immune responses in healthy participants without Alzheimer's pathology.
Researchers introduced a new method to measure firm capabilities, creating a 'capabilities ladder' to identify basic and advanced capabilities. The study found significant nestedness within the ladder, with firms at lower rungs having basic managerial, production, and communication capabilities.
Researchers at The University of Osaka used AI to evaluate characterization frameworks for molecular order in liquid water. They found that machine learning models can accurately capture key structural information, shedding light on the relationship between structural fluctuations and thermodynamic states of water.
A study by Chiba University researchers confirms Gentiana squarrosa obtains carbon through both photosynthesis and fungal symbiosis. The U-shaped pot cultivation system developed for this study enables the verification of carbon transfer between plants via AM fungi in various plant species.
Researchers at Kyushu University developed a new food preservation solution using pumpkin peel, creating a nanomaterial that slows deterioration of fruit and reduce transport damage. The material showed good biocompatibility and was effective in suppressing microbial growth and preserving freshness.
Optoelectronic tweezers (OETs) manipulate single cells through dielectrophoretic forces, offering a unique approach to cell capture, transport, sorting, analysis, and functional screening. OET integrates with microfluidics and other technologies for label-free single-cell physical parameter measurement and biomolecule manipulation.
Researchers found that targeting PAK1 enhances therapeutic efficacy of PARP inhibitors in ovarian cancer by impairing DNA repair. Combining olaparib with IPA-3, a PAK1 inhibitor, results in increased tumor cell killing and DNA damage accumulation.
A new study led by Dr. Anthony Lapsansky and Dr. Doug Altshuler found that pigeons make slow, subtle eye movements during flight to gather more information about their surroundings. This research has implications for the development of autonomous flying robots or drones, which can learn from bird-like visual strategies.
Researchers have successfully produced genome-edited T cells that can target and destroy cancer cells using the Platinum TALEN genetic engineering technique. The technique was found to be efficient, with an average yield of 72 million 1G4-TCR cells for every 3 million T-cells.
A biomaterial scaffold has been developed to recreate a skull stem cell niche, reducing craniosynostosis-related deformities and promoting normal skull growth. The triphasic scaffold maintained skeletal stem cells while supporting bone formation and tissue regeneration.
A study identified a brain pattern related to the tau protein that changes according to the stage of Huntington’s disease. The discovery opens doors to new biomarkers and treatments for this rare, hereditary neurodegenerative disease.
New research reveals alpine butterflies closely match local warming in range shifts, but habitat availability drives community composition and climate change response. The study finds that butterfly communities have become warmer-adapted over the past two decades, with specialist species vulnerable to elevational hostplant mismatches.
Researchers analyzed the composition of interstellar comet 3I/ATLAS, revealing high carbon and nitrogen isotopic ratios indicative of an outer solar system origin. The findings suggest 3I/ATLAS may be over twice as old as the Sun, shedding light on the formation history of this ancient celestial body.
Insilico Medicine has expanded its generative AI capabilities through a strategic collaboration with Liquid AI, yielding models optimized for retrosynthesis and multi-omics target discovery. The company's platform upgrades enable enterprise-grade automation, parallel simulation, and precision sifting in biologics design.
Scientists have successfully created programmable supramolecular polymers in neutral lipid environments, such as triolein-rich lipid droplets. This breakthrough provides a new method for regulating cellular functions and has potential applications in treating diseases involving lipid droplets.
A new carbon nanotube bandage provides a practical, deployable alternative for shape sensing in robots used in surgery. The sensor can be easily installed and offers real-time intraoperative guidance.
The Korea University College of Medicine and UNIST have been selected for the Ministry of Health and Welfare's K-MediST program, aiming to establish a leading model for integrated education and research in medical science and technology. The partnership will create an innovative interdisciplinary hub bridging medicine and engineering.
A team of researchers has developed chimeric allergen receptors that can suppress the immune system's response to common allergens, reducing or preventing asthma symptoms in mice. The technique could eventually be used to treat a wide variety of allergies in humans.
A study on coyote attacks in Stanley Park revealed that habituation and food conditioning contribute to aggressive behavior. To coexist with coyotes, people should not feed them, avoid approaching them, and be aware of their presence during certain times and locations.
Researchers uncover a previously unknown phase transformation mechanism in monolayer molybdenum telluride (MoTe2) that is fundamentally distinct from the conventional martensitic model. The study reveals a one-dimensional 'domino-like' chain reaction that triggers structural rearrangement and enables programmable electronic devices.
The Vaccine Innovation Center will develop a next-generation mRNA-based hantavirus vaccine using proprietary domestic technologies, leveraging self-amplifying mRNA and lipid nanoparticle delivery systems. Preclinical studies have demonstrated strong immunogenicity and protective effects.
A team of scientists has discovered 31 of the most ancient quasars ever found, including two that radiated light from a trillion suns when the universe was just 670 million years old. These findings provide crucial clues for understanding how supermassive black holes formed and offer insights into the early universe's structure.
The study found that primary care clinicians can make a significant impact on diabetes management by initiating continuous glucose monitoring, leading to improved glycemic control and reduced acute care utilization. This scalable strategy has the potential to improve diabetes outcomes in underserved populations.
A five-year study will focus on developing and evaluating compounds to treat best vitelliform macular dystrophy, a rare inherited retinal disease affecting the retina. The research aims to improve patients' lives by preserving sight.
Researchers found that frequency-specific transcranial photobiomodulation elicits complementary glial mechanisms for neurovascular protection and amyloid clearance in Alzheimer's disease. CW light primarily targeted astrocytes, while 40-Hz light drove microglial clustering around Aβ plaques.
A recent study published in Cancer Epidemiology, Biomarkers & Prevention found that men were more likely to be diagnosed with regional and distant stages of 20 nonreproductive solid cancer types in the United States. Men were significantly more likely than women to be diagnosed with regional tongue cancer, salivary gland cancer, oropha...
A new learning-based adaptive tuning method integrates chaotic search with particle swarm optimization to improve stability and solution quality in chaotic search algorithms. The approach consistently achieves better results than conventional methods, providing a practical means of enhancing the performance of chaotic search.