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American Association for the Advancement of Science (AAAS)


Implantable living materials autonomously deliver therapeutics using contained engineered bacteria

Researchers have introduced an implantable 'living material' that contains bacteria sensing infections and releasing therapeutic molecules on demand. Engineered living cells can autonomously sense disease and deliver treatment directly at affected sites, offering a new class of medicine that sustains itself in vivo.

Ravens don’t follow wolves to dinner – they remember where the food is

Researchers found that ravens rarely trail predators over long distances and instead rely on spatial memory to return to places where kills have occurred before. Ravens treat areas with historically high kill density as predictable foraging sites, indicating that navigation and memory play the dominant role in food source location.

Inside the brains of seals and sea lions with complex vocal behavior learning

Researchers have discovered specialized neural circuits in the brains of seals and sea lions that enable complex vocal behavior and learning. These circuits, including strong bilateral connections between the vocal motor cortex and brainstem nucleus ambiguus, are found in species with varying capacities for vocal flexibility and learning.

CAR-expressing astrocytes target and clear amyloid-β in mouse model of Alzheimer’s disease

Researchers have developed genetically altered astrocytes that express chimeric antigen receptors (CARs) capable of clearing accumulations of amyloid-β in the brains of mice. These CAR-expressing astrocytes, called CAR-A, substantially reduced Aβ buildup and prevented disease progression in a mouse model of Alzheimer’s disease.