Two large clinical trials found that vitamin D supplements did not reduce the risk of covid-19 or acute respiratory infections, contradicting previous studies' mixed results. The trials involved over 30,000 adults and showed no effect of vitamin D supplementation on infection rates or side effects.
Research using genetic variants as proxies for physical activity levels found a link between higher activity and lower invasive breast cancer risk. A higher overall level of genetically predicted physical activity was associated with a 41% lower risk of invasive breast cancer.
A small qualitative study found that emergency departments often fail to provide dignified and respectful care to frail older patients, leading to long waits and poor communication. The researchers recommend making healthcare settings more 'frailty friendly' by prioritizing patient comfort and involvement.
Experts argue that flawed narratives and premature scientific conclusions led to ineffective public health measures, care home deaths, and lax vaccination policies. The UK's response fell short of its potential, with a death toll approaching 200,000, due to a lack of evidence-based decision-making.
Two large studies found a link between high consumption of ultra-processed foods and increased risks of cardiovascular disease, bowel cancer, and death. The findings support policies limiting ultra-processed foods and promote eating unprocessed or minimally-processed foods for improved public health.
A recent investigation by The BMJ reveals that hospital trusts in England are bracing for a significant increase in energy bills this winter, with some anticipating a rise of over 200% in fuel costs. This would result in reduced patient care and staffing levels, posing a major challenge to the NHS's ability to operate effectively.
A large study found associations between steroid use and structural changes in brain white and grey matter, which may explain neuropsychiatric side effects. Steroid use was associated with reduced white matter structure and altered brain structures involved in cognitive and emotional processing.
Despite progress in women's participation and equal pay, sexist scheduling of major mixed-sex sporting fixtures perpetuates unequal opportunities for female athletes. Experts call for a rethink to enable women and girls to realize their full potential on and off the sports field.
Researchers found a lower concussion rate in Florida, where headgear was mandated, compared to states without. The rate was 0.39 concussions/1000 athlete exposures with mandatory headgear, vs 0.44 without. This suggests that headgear may be worth considering for high schools and other levels of play.
Research suggests that regular physical activity is linked to a lower risk of COVID-19 infection and severity, including hospital admission and death. Adults who engaged in at least 500 MET minutes per week had a significant reduction in risk, with the highest protective effect observed at this threshold.
Observational research suggests that 7-MX inhibits excessive eye lengthening and slows myopia progression in Danish children. The study found that higher doses of 7-MX were more effective in slowing myopia growth.
Advanced cervical cancer rates have been rising in the US, with a significant increase among White women and higher prevalence among Black women, particularly those in their mid-to-late 50s. The study found that obesity and older age at first birth may contribute to the rise in this type of cervical cancer.
Using standing desks alongside other measures reduced office workers' sitting time by about an hour a day over one year, leading to small improvements in stress, well-being, and energy levels. A height-adjustable desk was three times more effective than the standard SWAL intervention in reducing sitting time.
A large Canadian study found no association between Covid-19 vaccination during pregnancy and increased risks of preterm birth or stillbirth. The study analyzed data from over 85,000 births and concluded that vaccination is effective against Covid-19 in pregnant individuals and their newborns.
A 1g reduction in daily salt intake could prevent nearly 9 million cases of heart disease and stroke in China by 2030, saving 4 million lives. This is based on a modelling study that estimates the impact of reducing salt intake across the nation.
Intravenous (IV) nutrition is being used by professional athletes as a regular routine, despite lack of scientific evidence supporting its effectiveness and potential risks. The 'food first' approach is crucial to avoid normalization of unproven treatments.
A review of available monkeypox clinical guidelines found most were of low quality, lacking sufficient detail and failing to cover different risk groups. The lack of clarity between guidelines creates uncertainty for clinicians treating patients with monkeypox.
Researchers urge healthcare professionals to acknowledge changes in society around anal sex and have open conversations with young women to ensure they make informed choices about sex. Young women cite pleasure, curiosity, and coercion as factors for engaging in anal sex, which is associated with specific health concerns, including fae...
A pooled data analysis of 21 international clinical trials involving nearly 30,000 people found that salt substitutes lowered blood pressure and reduced the risk of heart attack, stroke, and early death. The benefits were consistent across different geography, age, sex, and health conditions.
Researchers developed an AI algorithm using individual ECG heartbeats to accurately predict diabetes and pre-diabetes. The DiaBeats algorithm detected the diseases with an overall accuracy of 97%, irrespective of factors like age, gender, and coexisting metabolic disorders.
A systematic review found that HPV vaccination significantly reduces the risk of cervical lesions recurrence, especially in cases related to high-risk HPV types. The study's results suggest that women treated for precancerous cervical lesions may benefit from receiving an HPV vaccine alongside surgical treatment.
A pooled data analysis found that experience of race discrimination is associated with a heightened risk of premature birth and low birthweight. The study highlights the importance of addressing racism in healthcare to improve health outcomes for marginalized communities.
Researchers found that daily consumption of small portions of Jarlsberg cheese increased osteocalcin, a hormone associated with strong bones and teeth, without boosting harmful cholesterol levels. The effects were specific to Jarlsberg and not seen in other cheeses.
A statistical analysis of 200 years of data across all continents reveals that between 25-50% of men outlive women, particularly in developed countries. The study highlights the impact of education, marital status, and external factors on sex differences in lifespan.
A study of 197 confirmed monkeypox cases in London found differences in symptoms between the current outbreak and previous ones. Key findings include rectal pain, penile swelling, and solitary lesions not previously known to be typical features of monkeypox infection.
In India, two out of five eligible children are missing out on preventive vitamin A supplementation, with wide variations in coverage among and within states. The analysis found large 'cold spots' in provision across the country, ranging from just under 13% to 94.5%, and distinct geographical hotspots and coldspots.
Research suggests that up to 5.6% of patients may experience persistent smell loss, while 4.4% may not recover their sense of taste after COVID-19 infection, with recovery rates increasing over time.
Chronic lung disease (COPD) is a major public health problem worldwide, affecting 212 million people, primarily due to smoking and air pollution. The study reveals that while age-adjusted rates have declined, absolute counts are rising, with COPD expected to become an even greater issue in the future.
A pooled data analysis of 11 international studies found that NAFLD is associated with a 50% heightened risk of developing heart failure. The severity of NAFLD also increases the risk, especially with extensive liver fibrosis.
A survey of UK doctors found that the pandemic has led to an increase in willingness to forgo life-saving treatments for very sick patients, while views on euthanasia and assisted dying have remained unchanged. The COVID-19 pandemic has transformed end-of-life care, prompting a reevaluation of clinicians' decision-making processes.
Researchers assessed 539 videos from 16 leading food and beverage brands on TikTok, finding that unhealthy food marketing is prevalent among children. The study highlights the need for policies to protect kids from the harmful impact of food marketing on social media platforms.
A recent study found that COVID-19 vaccines significantly reduced the risk of infection among NHS hospital workers in England during the second wave. The research showed that without vaccination, staff absence could have been 69% higher and infections peaked in late December 2020.
The proportion of healthy-weight young people trying to shed pounds in England has nearly tripled from around 1 in 20 to nearly 1 in 7 over 20 years. Reported slimming attempts among all children, particularly those who are overweight and obese, have shot up, surpassing the rise in excess weight gain and service provision.
The NHS is facing a critical crisis due to the failure to recognize the ongoing threat of COVID-19. Weekly admissions for COVID-19 have averaged over 9,000, with elective activity 10% below pre-pandemic levels.
Research on Scotland's minimum unit pricing (MUP) policy found that it was associated with larger reductions in consumption among heavier drinkers, but not among women or those who tend to drink less heavily. Consumption actually increased among the heaviest drinking men following MUP introduction.
Research suggests that overly restrictive salt intake may worsen outcomes for people with a common form of heart failure, particularly in younger individuals and those of black and other ethnicities. The study found that participants who consumed more salt had a lower risk of hospital admission for heart failure.
The WHO advises against the use of colchicine and fluvoxamine for treating non-severe COVID-19, citing insufficient evidence and potential harms. No recommendation is made for these drugs in patients with severe or critical illness.
A recent study published by The BMJ confirms previous reports that myocarditis is rare but cases are highest among young males shortly after a second dose of mRNA vaccine, especially Moderna. The risk of myocarditis or pericarditis might be lower when the second dose is given more than 30 days after the first dose.
A cluster of studies published in BMJ Group found that universal UK school-based mindfulness training had weak evidence for effectiveness and short-lived benefits. The research suggests that other approaches, such as social-emotional learning (SEL), may be more suitable for building psychological resilience in young people.
Thousands of people with long covid are traveling abroad for expensive, unproven treatments like apheresis and anti-clotting therapy. Experts question the safety and effectiveness of these treatments, citing inadequate consent forms and lack of evidence.
A study found that rates of serious complications associated with shoulder surgery are low, but one in 26 patients need further surgery within a year. The effectiveness of some shoulder procedures is doubtful at best, according to experts.
A study using data from the Surveillance, Epidemiology, and End Results database found that married individuals had better survival prospects than divorced or widowed people. The researchers developed a nomogram to predict 3-5 year survivals, with marital status being one of several independent prognostic factors.
A case report highlights the dangers of excessive vitamin D intake, with symptoms including abdominal pain, leg cramps, and kidney abnormalities. Doctors warn that hypervitaminosis D is on the rise and can lead to serious health problems if not taken safely.
A pooled data analysis of available research found that ADHD drugs may successfully treat key aspects of Alzheimer's disease. Noradrenergic drugs, which target the neurotransmitter noradrenaline, showed a small but significant positive effect on overall cognition and a large positive effect on apathy in patients with Alzheimer's disease.
A water birth significantly reduces the use of epidurals, injected opioids, episiotomy, pain, and heavy bleeding after birth, while increasing mothers' satisfaction levels and the odds of an intact perineum. A water immersion also increases the likelihood of an intact perineum and reduces episodes of umbilical cord breakage.
A review of 18 studies suggests that long distance airborne transmission of SARS-CoV-2 can occur in indoor settings, particularly with poor ventilation. The evidence supports the role of mitigation measures, such as adequate ventilation, to prevent transmission.
A study finds that regulatory agencies are heavily influenced by industry money, leading to concerns about their independence. Experts call for structural changes and a watchdog agency to restore regulators' ability to make unbiased decisions.
Research finds that cannabis users have a significantly higher risk of emergency room visits and hospital admissions for any cause. However, the study did not find a significant link between cannabis use and respiratory health issues. The authors conclude that further research is needed to confirm their findings.
A recent study published in Open Heart found that heart failure is discussed less frequently in public discourse than conditions like cancer and dementia, with 'heart failure' mentioned just 0.28 times per million words in UK parliamentary debates between 1945 and early 2021.
A large analysis of reproductive health data has found a significant association between infertility, miscarriage, and stillbirth with an increased risk of non-fatal and fatal stroke in women. Women who experienced recurrent miscarriages or stillbirths were at higher risk of stroke, particularly those with a history of infertility.