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Brown University


In Africa, STI testing could boost HIV prevention

A new study suggests that testing for sexually transmitted infections (STIs) when testing for HIV can improve HIV prevention efforts in South Africa and the broader region. The study found that patients with HIV were more likely to contract STIs before starting treatment, highlighting the importance of simultaneous STI detection and tr...

SourceBrown University·JournalSexually Transmitted Infections·DateMay 28, 2014

A habitable environment on Martian volcano?

A Martian volcano, Arsia Mons, may have supported one of the most recent habitable environments on the Red Planet. Researchers found evidence of englacial lakes and volcanic lava flows that could have created a liquid water environment suitable for microbial life. The discovery is significant as it suggests that such environments may h...

SourceBrown University·JournalIcarus·DateMay 27, 2014

People attribute free will to mind, not soul

A new study suggests that people's perception of free will is based on the agent's ability to make intentional and independent choices, regardless of their spiritual beliefs. The study found that participants generally attributed free will to humans with mental capacity, but not to those without.

SourceBrown University·JournalConsciousness and Cognition·DateMay 27, 2014

Tiny muscles help bats fine-tune flight, stiffen wing skin

Researchers at Brown University discovered that tiny muscles called plagiopatagiales embedded in a bat's wing membrane can adjust stiffness and curvature during flight, fine-tuning aerodynamic performance. The muscles tense on the downstroke and relax on the upstroke, working in synchrony to stiffen the wing.

SourceBrown University·JournalBioinspiration & Biomimetics·DateMay 23, 2014

Newborn health improves despite income gap

A review of recent economic research found that newborn health has improved nationally in recent years, with a decrease in low birth weight among disadvantaged mothers over the last 20 years. This improvement is attributed to increased public policies and programming aimed at improving prenatal and postnatal care.

SourceBrown University·JournalScience·DateMay 22, 2014

Getting chemo first may help in rectal cancer

A new chemotherapy regimen administered before surgery and chemoradiation improves tolerance to treatment in most rectal cancer patients. The study found that over 90% of patients were able to complete a full course of standard treatment, with many experiencing a significant reduction in symptoms.

Study finds genetic patterns in preeclampsia

Researchers identified distinct genetic underpinnings for different manifestations of preeclampsia, including early vs. late timing and high severity levels. The study found unique sets of genes involved from both mother and fetus, suggesting specific biological contributions to the condition.

SourceBrown University·JournalObstetrics and Gynecology·DateMay 7, 2014

As kids age, snacking quality appears to decline

Research found that snacking frequency and diet quality differ by age in schoolchildren, with younger kids benefiting from snacks and teens negatively affected. Nutrient-rich snacks can be a key to improving diet quality in children, especially as they enter adolescence.

SourceBrown University·JournalPublic Health Nutrition·DateMay 6, 2014

Impact glass stores biodata for millions of years

Asteroid and comet impacts can preserve the signatures of ancient life in Earthly impact debris. Researchers found fragments of leaves and preserved organic compounds in ancient impact glasses from Argentina, which could provide a snapshot of environmental conditions at the time of those impacts.

SourceBrown University·JournalGeology·DateApr 18, 2014

HIV+ women respond well to HPV vaccine

A clinical trial found that HIV-positive women build antibodies against HPV and experience no unusual safety issues after vaccination. The study's results counter doubts about the vaccine's effectiveness in this population, suggesting it is safe and beneficial for those with weakened immune systems.

SourceBrown University·JournalClinical Infectious Diseases·DateApr 16, 2014

Wiring for smell sets up early, then persists

Brown University scientists found that the fundamental neural wiring map between the nose and brain becomes established in early development and remains unchanged throughout life. The study's findings provide insight into neurodevelopmental disorders and may have implications for regenerative medicine.

SourceBrown University·JournalScience·DateApr 10, 2014

New epidemiology model combines multiple genomic data

A new epidemiology model developed by Brown University researcher Yen-Tsung Huang integrates genomic data from SNPs, gene expression, and methylation to find significant associations with diseases like asthma and brain cancer. The model improves performance and validity across different subjects, paving the way for further applications.

SourceBrown University·JournalBiostatistics·DateApr 8, 2014

A new twist makes for better steel, researchers find

Researchers at Brown University have discovered a method to fortify steel by twisting it, allowing for improved strength while maintaining ductility. This breakthrough could lead to the development of new steel alloys for high-strength applications such as axles on high-speed trains.

SourceBrown University·JournalNature Communications·DateApr 8, 2014

Doctor's specialty predicts feeding tube use

A new study by Brown University researchers found that hospital attending physicians' specialties are linked to the likelihood of patients receiving gastric feeding tubes, which is not recommended for frail, terminal patients. The study analyzed tens of thousands of cases over a decade and found that patients cared for by primary care ...

SourceBrown University·JournalHealth Affairs·DateApr 7, 2014

Hot mantle drives elevation, volcanism along mid-ocean ridges

Scientists have found that temperature variations deep within the Earth's mantle influence mid-ocean ridge elevation and volcanic hotspots, resolving a long-standing controversy. The study analyzed seismic wave data and rock chemistry to determine that higher mantle temperatures are associated with thicker crust and volcanic activity.

SourceBrown University·JournalScience·DateApr 3, 2014

Research method integrates meditation, science

A team of Brown University researchers have developed a methodology to integrate mindfulness experiences with brain imaging, allowing for the formation of testable hypotheses about the science and mental health benefits of meditation. By employing structured coding of self-reported personal experience, they can correlate mental states ...

Ancient Indonesian climate shift linked to glacial cycle

Researchers from Brown University have assembled a 60,000-year record of rainfall in central Indonesia, showing that the region's normally wet climate was interrupted by a severe dry period during peak ice age. This finding provides crucial data for predicting how the region might respond to global warming.

SourceBrown University·JournalProceedings of the National Academy of Sciences·DateMar 24, 2014

Study proposes new ovarian cancer targets

Scientists have identified a set of proteins called TAFs that may play a role in the development of ovarian cancer. Studies found that these proteins are overexpressed or underexpressed in 73% of tumors, suggesting they could be potential targets for new treatments.

SourceBrown University·JournalFrontiers in Oncology·DateMar 13, 2014

Returning vets face 'warring identities' distress

A recent study explores the mental state of returning veterans, finding that many struggle with identity conflict and feel 'alien' among family and friends. The research highlights the need for broader dialogue around veteran experiences beyond diagnosable illnesses like PTSD.

SourceBrown University·JournalSociety and Mental Health·DateMar 6, 2014

An inventive new way to profile immune cells in blood

A new technique uses DNA methylation signatures to detect immune cell types in blood samples, showing high accuracy compared to existing methods. The approach counts specific chemical alterations that distinguish between cell types, enabling researchers to understand the unique signature of each cell type.

SourceBrown University·JournalGenome Biology·DateMar 5, 2014

Experts call for prison health improvements

The article highlights the need for improved prison healthcare, citing that over 95% of prisoners will return to the community with significant health burdens. Experts recommend alternatives to imprisonment, improved oversight, and a 'risk-needs-responsivity' model to address chronic medical conditions and substance abuse after release.

SourceBrown University·JournalHealth Affairs·DateMar 3, 2014

Research maze puts images on floor, where rodents look

Rodents learn visual tasks in a fourth to sixth the number of trials when stimuli are projected onto the floor, outperforming traditional wall projections. Automated visual cognitive research tasks with neural activity recording and brain stimulation can be performed efficiently.

SourceBrown University·JournalJournal of Visualized Experiments·DateFeb 26, 2014

Analysis: 32 years of US filicide arrests

A study of US filicide arrests over 32 years found that men are as likely to kill infants as women, and stepchildren are not more likely than biological children to die at their parents' hands. The data also revealed that fathers were more likely to be the alleged murderers of adult children.

SourceBrown University·JournalForensic Science International·DateFeb 25, 2014

Higher risks among perinatal women with bipolar disorder

A study published in the Journal of Affective Disorders found that pregnant and postpartum women with bipolar disorder experience significant mental health problems, including self-harm, substance abuse, and complications during delivery. Researchers emphasize the importance of proper diagnosis and treatment to mitigate these risks.

SourceBrown University·JournalJournal of Affective Disorders·DateFeb 24, 2014

Study reveals workings of working memory

Researchers at Brown University discovered that working memory uses similar brain circuits to those involved in planning motion. They found that the caudate and dorsal anterior premotor cortex contribute to output gating, a crucial process for selecting from working memory. The study's findings provide insight into how the brain effici...

SourceBrown University·JournalNeuron·DateFeb 19, 2014

Obesity in Samoa: A global harbinger?

A recent study found that Samoa's adult population is almost three-quarters obese, with type 2 diabetes rates over one in five. The island's unique genetic profile and environmental factors are being investigated to understand the causes of this obesity crisis. This phenomenon may serve as a harbinger for global health difficulties.

Study finds high Rx burden for bipolar patients

A study of 230 bipolar I disorder patients found that nearly a third were taking four or more psychiatric medications, with an average of six different drugs. Women were significantly more likely to experience complex polypharmacy, taking 68% of these high medication burden cases.

SourceBrown University·JournalPsychiatry Research·DateFeb 4, 2014

Interventions work to stem freshman drinking

A systematic review of data from over 40 studies found that colleges can reduce freshman drinking by implementing personalized feedback reports, which significantly helped students to reduce their drinking frequency, quantity, and alcohol-related problems. Interventions combining multiple techniques proved most effective in reducing fi...

SourceBrown University·JournalJournal of Consulting and Clinical Psychology·DateJan 23, 2014

Disappointing Alzheimer's trial yields new ideas

A recent Alzheimer's trial failed to produce cognitive improvement for volunteers, but researchers have identified key takeaways to inform the development of new treatments. Lessons learned include testing drugs in individuals building up amyloid plaques, giving higher doses safely, and combining disease-modifying treatments.

SourceBrown University·JournalNew England Journal of Medicine·DateJan 22, 2014

Clever chemistry improves a new class of antibiotics

Researchers have developed a new class of antibiotics called acyldepsipeptides (ADEPs) that kill bacteria in a unique way by altering protein degradation pathways. By modifying the ADEP molecule's structure to make it more rigid, they increased its potency up to 1,200 times that of the naturally occurring molecule.

SourceBrown University·JournalJournal of the American Chemical Society·DateJan 17, 2014

Seniors moving to HCBS face more hospital risk

A new study found that seniors transitioning from nursing homes to home and community-based care (HCBS) face a 40% greater risk of preventable hospitalizations. The practice resulted in more hospitalizations among seniors dually eligible for Medicaid and Medicare due to inadequate medical support services in community settings.

SourceBrown University·JournalJournal of the American Geriatrics Society·DateJan 8, 2014