A Cancer Research UK study found that almost three-quarters of overweight or obese 13-15-year-olds are in the normal-weight range. The study showed that only around 40% of these teens thought they were too heavy, while seven per cent believed they were too light.
Studies of oesophageal tumour samples reveal that L1 elements can alter cell growth and division, potentially leading to cancer. Mobile genetic sequences are found to occur around 100 times in each tumour sample, with some occurring up to 700 times.
A recent study published in Nature has revealed that adding the female hormone progesterone to treatment could benefit around half of all breast cancer patients. The research, led by Cancer Research UK, showed how the progesterone receptor 'talks' to oestrogen receptors in breast cancer cells, ultimately slowing down tumour growth.
A new study by Cancer Research UK found that breast cancer patients are disproportionately affected, with only 20% having surgery after an emergency diagnosis in hospital. In contrast, those diagnosed via urgent GP referrals have a much higher likelihood of receiving lifesaving surgery.
Researchers have discovered how combining AKT inhibitors with radiotherapy may improve cancer treatment outcomes. The study found that targeting specific genes can enhance the efficacy of radiotherapy across various cancer types.
Researchers found that women who adhered to a Mediterranean diet most closely lowered their risk of womb cancer by more than half. The diet's components included eating lots of vegetables, fruits and nuts, pulses, cereals and potatoes, fish, monounsaturated fats, and moderate alcohol intake.
A Cancer Research UK study found that pre-surgery chemotherapy reduces side effects and hospital stays, leading to a better quality of life for patients. The trial challenged the international standard for treating advanced ovarian cancer.
Research by Cancer Research UK has identified a link between high estrogen levels and an increased risk of male breast cancer. Men with the highest levels of oestrogen were two and a half times more likely to develop breast cancer.
A Cancer Research UK study found that only a third of bowel cancer patients received physical activity advice, despite evidence showing its link to better survival rates. Most patients who received advice were more likely to be physically active than those who didn't.
Scientists have identified a 'safe haven' effect in melanoma cells that shields them from targeted treatments. Adding a second experimental drug targeting a protein called FAK has shown promising results in slowing down tumor growth and improving cell death rates.
Cancer Research UK scientists found that mutations in the KRAS gene interfere with protective self-destruct switches, allowing cancer cells to grow and spread. The research may lead to tailored treatments for pancreatic and non-small cell lung cancers.
Researchers mapped genetic changes in tumor samples from 10 men with prostate cancer, revealing a common ancestral cell and shared gene faults. The study provides insight into how prostate cancer spreads and evolves, potentially leading to new treatment targets and personalized approaches.
A Cancer Research UK review found that older people, women, and less affluent individuals are at a higher risk of emergency cancer diagnoses. The study also revealed that emergency-diagnosed cancers tend to have poorer survival rates compared to those diagnosed through other routes.
Researchers at CRT and Bioinvent are developing antibodies targeting OX40 and 4-1BB, 'co-receptors' that stimulate killer T-cells. The goal is to reverse tumour cell suppression of immune responses, allowing the immune system to fight cancer.
Research links genetic changes in bowel tumours to immune system responses, suggesting potential for targeted immunotherapy treatments. Genetic profiles could be used to diagnose suitability for immunotherapies and tailor treatment plans.
A Cancer Research UK study found that text message reminders increased breast cancer screening attendance by 20% among women aged 47-53. The trial, which sent text messages to over 450 women, showed that 72% of those who received the reminders attended their appointments compared to 60% of those who did not.
Scientists have identified 15 new genetic 'hot-spots' linked to an increased risk of breast cancer, with some women having multiple variations that double their risk and others being three times more likely to develop the disease. The discovery could help identify high-risk women and improve cancer screening and prevention.
New research shows that non-cancerous prostate cells with genetic mutations can develop into cancer, potentially explaining why prostate cancer often has multiple genetically different tumours. This discovery could lead to a rethink of treatment strategies and improve outcomes for men with the disease.
A Cancer Research UK study found that serous ovarian cancers with diverse genetic profiles are more likely to become resistant to chemotherapy and recur. This variability affects the prognosis of patients with these tumors, leading to earlier deaths compared to those with less varied tumors.
A study found that most UK women (85%) would back the idea of more frequent breast screening if they are at higher genetic risk of developing breast cancer. Women at lower genetic risk were less supportive, but still willing to participate in screening with proper information and support.
New research suggests that cancer false alarms could lead to patients delaying symptom checks due to a lack of support. A systematic review found that over-reassurance and under-support can discourage patients from seeking help for new or recurrent symptoms.
A Cancer Research UK study found that nine in 10 people think cancer screening is 'almost always a good idea', despite low uptake. The researchers highlight the need for clearer information on risks and benefits to encourage informed decision-making.
A Danish study found that children with higher BMI between 9-13 years old were more likely to develop oesophageal cancer later in life. The study suggests that childhood obesity may be directly linked to an increased risk of esophageal cancer as adults, and highlights the importance of maintaining a healthy weight in children.
A new forecast from Cancer Research UK suggests that 1 in 2 people in the UK will develop cancer at some point in their lives. The increased risk is primarily due to more people living into older age, when cancer is more common.
A Cancer Research UK study found that people who dismiss their symptoms as trivial or worry about wasting the doctor's time may delay cancer diagnosis. The study discovered that many individuals with red-flag cancer warning symptoms felt they didn't need medical attention, fearing it would be seen as a sign of weakness.
Researchers at UCL found that people are more successful in quitting smoking, starting exercise, or losing weight when their partner makes a change. The study of over 3,722 couples aged 50+ shows that men and women are equally affected by their partners' behavior changes.
A Cancer Research UK study found that nearly 40% of people with abnormal test results ignore their next screening invitation, while just 13% of those with normal results do the same. The study highlights a small but high-risk group failing to continue with bowel cancer screening tests.
Researchers found that lung cancer cells sever protein ties, allowing them to break loose and spread. Targeting this process could stop lung cancer from spreading by keeping cells stuck together.
Researchers discovered specific genetic paths that medulloblastoma follows when it relapses, identifying potential subsets of patients treatable with existing drugs. The study suggests taking additional tumor samples at recurrence could lead to more effective treatments.
Researchers have found that loss of gene PTEN is a common driver event behind high-grade serous ovarian cancer, which is often fatal. Combining image analysis with genetic data helped identify PTEN levels in cancer cells while ignoring normal cells, paving the way for new treatments.
A study by Cancer Research UK found that individuals with low numeracy skills are more likely to feel negative about bowel cancer screening, including fearing abnormal results. They also tend to think the test is disgusting or embarrassing.
Researchers identified a critical pathway that enables cancer cells to survive despite DNA errors, relying on the PKCƐ signal pathway. Disrupting this pathway could trigger cancer cells to self-destruct, offering a new strategy to beat the disease.
A study by Cancer Research UK found that people often dismiss cancer symptoms as less serious and attribute them to other causes. Only two per cent thought cancer was a possible cause, despite experiencing red-flag symptoms such as unexplained coughs or persistent changes in bowel habits.
A new study challenges the prevailing view of how bowel cancer develops in the large intestine. Cancer Research UK scientists discovered that faulty genes can cause normal cells to behave like immortal stem cells, leading to tumour formation.
Researchers at Cancer Research UK have identified over 400 areas of hidden faults in the human genome, which could conceal cancer-causing gene mutations. These 'blind spots' are difficult to detect using current gene-reading technology, highlighting opportunities for new diagnostic tests and treatments.
A majority of obese people in Britain deny being obese, describing themselves as 'just right' or 'very overweight' instead. The study suggests that media coverage and public health campaigns may be contributing to this phenomenon, as people become less likely to recognize the health risks associated with their weight.
A trial revealed that patients with a specific type of esophageal cancer who received the lung cancer drug gefitinib survived longer, with some patients living up to six months beyond their initial treatment. The drug has shown promise as a targeted treatment for this disease.
Researchers found a new strategy and potential drug to target faulty Ras protein, which causes cancer by producing excess signals. This breakthrough offers opportunities for developing new treatments that exploit the discovery without harming healthy cells.
Researchers discovered genetic patterns that predict when breast cancers will spread to the brain, offering a potential early detection method. Faulty gene switches in the original tumor may serve as an early warning signal for brain metastasis.
Patients with emergency-diagnosed lung cancer reported difficulties in seeing their general practitioner (GP), including lack of confidence and fear of diagnosis. Nearly half of the patients delayed seeking medical attention for over 12 weeks, highlighting the need for improved patient education and rapid-access diagnostic clinics.
A new trial has shown the Cytosponge test to be an accurate and safe way of diagnosing Barrett's Oesophagus. The test involves swallowing a sponge on a string and has been proven to be more effective than traditional endoscopy for detecting the condition.
A recent study found that nearly half of smokers in the UK's Royal Castle FagEnds study used e-cigarettes to help quit. Many viewed e-cigarettes as a less effective alternative to traditional quitting methods, and some were misinformed about their risks.
Researchers found that eribulin improves overall survival of women with metastatic triple negative breast cancer and HER2 negative breast cancer by nearly five months and two months respectively. Eribulin, originally developed from sea sponges, is a microtubule inhibitor that stops cancer cells from separating into new cells.
A comprehensive review of 19,000 scientific papers identified more than 800 cancer-specific biomarkers that could lead to a single blood test for early detection of many types of cancer. The study aims to develop a screening test from a single blood sample for multiple cancer types.
A pilot study found that invisible fluorescent tattoos can improve body confidence among breast cancer patients undergoing radiotherapy. Researchers compared the effects of visible and invisible tattoos on patients' self-esteem, finding that 56% of those with invisible tattoos felt better one month after treatment.
Researchers have successfully triggered the self-destruct process in lung cancer cells, paving the way for a new treatment approach that leaves healthy cells unharmed. The breakthrough was achieved using a combination of two drugs, TRAIL and a CDK9 inhibitor, which altered the molecular switches in the cell suicide process.
Researchers have identified unique molecular fingerprints for 11 types of children's tumours, which could be used to develop blood tests to diagnose these cancers. This may eventually lead to a quicker and more accurate way to diagnose tumours.
Researchers discovered that dendritic cells trigger lymph node expansion by producing CLEC-2, allowing immune cells to gather and launch an attack against infections and cancer. The study provides new insights into the immune system's role in diseases, including cancer.
Researchers found melanoma cells create their own 'green light' signal using lysophosphatidic acid (LPA) to spread quickly and aggressively. This 'breadcrumb trail' allows cancer cells to travel rapidly around the body, making treatment challenging.
Researchers discovered that lung cancers can exist undetected for many years due to unique genetic faults in separate areas of the tumor. The study highlights the need for better early detection methods to improve treatment outcomes, as two-thirds of patients are diagnosed with advanced disease when treatments are less effective.