A new species of lizard, Indrasaurus wangi, was discovered in the stomach of Microraptor zhaoianus, revealing a unique diet and expanding Cretaceous diversity. The finding supports the interpretation that Microraptor was an opportunistic predator feeding on various prey.
Research reveals that epigenetic regulation-mediated metabolic reprogramming enables lung cancer cells to adapt to and resist targeted therapies. BCAT1 upregulation allows for glutathione generation, eliminating oxidative stress and promoting drug resistance.
A new Y-shaped synthetic consortium achieves 21 g/L butanol yield, exceeding theoretical value by 85%. The consortium's adaptability and stability enable efficient simultaneous utilization of mixed sugar ratios and aeration conditions.
The Tibet ASgamma experiment has discovered the highest energy gamma rays ever observed from an astrophysical source, exceeding 450 TeV. The most energetic gamma rays were produced by interaction between high-energy electrons and cosmic microwave background radiation.
Researchers have proposed a gait-based identification method for elderly users using wearable devices, improving the accuracy of authentication for older adults. The method uses a gait template synthesis algorithm and arbitration-based score-level fusion to alleviate intra-subject gait fluctuation.
Researchers found that ATL-mediated membrane tethering plays a critical role in maintaining cargo mobility and COPII formation in the ER. In ATL-deleted cells, cargo packaging into COPII vesicles was significantly reduced, highlighting the importance of ATL in regulating membrane trafficking.
Researchers have discovered a new high-temperature superconductor (Ba2CuO4-δ) with a transition temperature above 73K, featuring an exceptionally compressed local octahedron and heavily over-doped hole carriers. This finding challenges the long-held scenario of superconductivity in cuprates.
Research teams discovered that uridine diphosphate glucose accelerates SNAI1 mRNA decay, impairing lung cancer metastasis. Lower UDP-glucose levels are associated with higher metastasis and recurrence rates in lung cancer.
Scientists discover that UDP-glucose accelerates SNAI1 mRNA decay, impairing lung cancer metastasis. The study also uncovers how UDP-glucose converts to UDP-glucuronic acid, enhancing SNAI1 mRNA stability and promoting tumor cell migration.
The 2015 Gorkha earthquake's rupture length was likely controlled by spatial variations in the Main Himalayan Thrust, according to a new study led by Prof. BAI Ling from the Institute of Tibetan Plateau Research. The researchers used seismic waveforms and waveform modeling to determine source parameters and velocity structures.
Researchers have developed a chiral separation membrane using two-dimensional layered materials, showing high selective permeation efficiency among various enantiomers. The membrane can efficiently separate left-handed and right-handed molecules like limonene, with potential applications in sewage processing and desalination.
Researchers developed a bionic stretchable nanogenerator inspired by electric eels, generating up to 170V under dry conditions. The technology has potential for wearable devices, human motion monitoring and underwater rescue applications.
Scientists discovered resonance-enhanced tunneling as the key to the F + H2 reaction's rapid reactivity, essential for understanding interstellar chemistry. The research found that resonance states are crucial for overcoming the energy barrier, enabling the observed HF in interstellar clouds.
Researchers from Chinese Academy of Sciences crack long-solved mystery by elucidating MPA biosynthetic pathway, revealing unique cooperation between enzymes and catabolic machinery. The study also sheds light on compartmentalized biosynthesis in fungi and plants.
Researchers have identified different forces behind variations in near-surface temperature with elevation, time, and space on the Third Pole. This new understanding will provide a more accurate basis for modeling and predicting glacier movement, forestry, and agriculture in the region.
A new sediment core from Zipingpu Reservoir provides direct evidence of the link between a large earthquake and its sedimentary signature. The study found that hydrological forcing played a crucial role in transporting debris downstream, even in proximal locations.
A new study has identified the PcG protein EED as a critical modulator of hippocampal development and function. The researchers found that EED is necessary for the proper formation of the dentate gyrus, a key region involved in learning and memory.
Researchers at Chinese Academy of Sciences create a chemocatalytic approach to produce cellulosic ethanol, achieving an ethanol yield over 40% in a one-pot process. The new method could overcome limitations on ethanol concentration and show great potential for practical production.
Archaeologists and laboratory scientists discovered psychoactive compounds in ancient incense burners from the Pamir Mountains, indicating higher levels of THC. This study provides clear evidence that ancient people in eastern Central Asia used cannabis for its psychoactive properties.
A new neural circuit related to VTAGABA+ neurons mediates visually evoked innate defensive responses, involving the SC Glut+_ VTAGABA+_ CeA pathway. This discovery provides insights into potential mechanisms of survival across species and maladaptive behavior in fear- and anxiety-related mental disorders.
Researchers have created a primate model of autism using genome-editing technology, revealing insights into the genetic basis and potential treatments for neurodevelopmental disorders. The study's findings have significant implications for developing better treatment options for autism spectrum disorder.
Researchers have discovered that DNA base editors can induce tens of thousands of off-target RNA single nucleotide variants (SNVs). To address this issue, they engineered deaminases to eliminate the off-target effects, providing a solution for the clinical application of these methods.
Researchers have developed a method to produce diesel fuel and hydrogen by harnessing light energy and biomass-derived feedstocks. The process uses light energy to drive the valorization of downstream biomass products, resulting in high-light transformation efficiencies and higher rates of hydrogen production.
Researchers have created a graphene-based sandwiched superstructure that enables efficient transport of nanoparticles inside cell membranes, outperforming traditional carriers in anti-cancer efficacy. This discovery could significantly improve cytotoxicity effects and pave the way for novel membrane-specific drug delivery modes.
Researchers discover parvifoline AA, a natural compound, stimulates NKG2D ligands on cancer cells, making them more recognizable and targetable by NK cells. This increases the effectiveness of NK cell-based tumor immunotherapy.
Researchers have discovered a new substance that can form during the oriented attachment (OA) process of crystal growth, which may deepen our understanding of crystal formation mechanisms. The discovery was made using state-of-the-art experimental methods and theoretical calculations.
Researchers create a surface acidity- and selectivity-tunable manganese oxide catalyst using enolic acetylacetones. The stable modification of acetylacetones influences the redox-acid cooperative catalysis of MnOx, enabling control over oxidation selectivities.
Researchers summarize the latest progress in low-temperature methane conversion using thermocatalytic, electrocatalytic, and photocatalytic systems. The study highlights the importance of coupling multiple driving forces to activate methane and introduces catalyst design viewpoints for future technology development.
A new method called plainification aims to enhance material properties by creating stable interfaces between grains at different scales, using fewer or no alloying elements. This approach could lower material costs, increase resource independence, and boost recyclability, paving the way for more sustainable materials development.
Researchers developed a thermoelectric module based on liquid-like materials, achieving a record-high energy conversion efficiency of 9.1%. The Cu2Se/Yb0.3Co4Sb12 TE module showed excellent service stability when the ratio of cross-sectional areas between p- and n-legs was higher than four.
Researchers from the Chinese Academy of Sciences uncovered the structural and functional mechanism of SigI/RsgI factors, a new class of σ/anti-σ factors responsible for regulating cellulosomes in Clostridia and Bacilli. The study reveals a unique complex structure and critical recognition specificity among different pairs of proteins.
A new surface tension-controlled crystallization method has been developed to prepare large 2D perovskite single crystals, achieving exceptional device performance. The crystals exhibit anisotropy-dependent optoelectronic properties, with high responsivity and external quantum efficiency.
The Chang'E 4 mission has collected new evidence from the largest crater in the solar system, shedding light on the moon's composition and evolution. The findings suggest that the lunar mantle may consist of equal parts olivine and pyroxene, contradicting previous theories.
Researchers create high-performance organic phototransistors using a novel hybrid-layered architecture that combines charge-trapping effect and efficient carrier transport, enabling enhanced photodetection performance. The devices show excellent flexibility and reliability in photosensitive imaging systems.
Scientists have discovered a 99-million-year-old piece of amber containing diverse coastal organisms, including sea snails, slaters, and terrestrial creatures like mites and spiders. The finding sheds light on the unique preservation process that trapped these animals in the amber.
Researchers developed a new class of single-atom nanozymes with intrinsic enzyme-like active sites, overcoming conventional nanozyme drawbacks. The discovery provides a new perspective on catalytic mechanism and rational design of nanozymes.
A new species of Jurassic scansoriopterygid dinosaur with associated feathers and membranous tissues has been discovered, providing new insights into the origin of flight in Dinosauria. The well-preserved skeleton of Ambopteryx longibrachium preserves a unique wing structure supported by a rod-like wrist bone.
The study provides new insights into the functional role of the PPC in decision-making, showing that it plays an essential role in making judgments about unknown sensory stimuli. The researchers used a novel behavioral technique and precise manipulation of neuronal activity to demonstrate the causal role of the PPC during decision-making.
A recent study published in Nature confirms that Denisovans lived on the Tibetan Plateau during the Middle Pleistocene era. The discovery of a 160,000-year-old human mandible found in Xiahe, China, provides evidence of an early human presence on the plateau, predating modern humans.
A joint China-UK-Russia research team found that oxygen levels played a fundamental role in the Cambrian Explosion of animals. The study analyzed ancient seawater chemistry and determined that evolutionary radiations followed a 'boom and bust' pattern in tandem with oxygen levels.
A Middle Pleistocene human skull found in southeastern China exhibits morphological similarities to other East Asian archaic human remains but also foreshadows later modern human forms. The discovery provides evidence for regional continuity in human evolution during the region's Pleistocene era.
Researchers found indica rice varieties had more bacteria associated with nitrogen metabolism, leading to higher nitrogen-use efficiency. The study established a model using random-forest machine-learning approach and identified NRT1.1B as key factor in root microbiota composition.
Researchers have developed a new catalyst for oxygen evolution, achieving higher catalytic activity and lower overpotential than traditional methods. The study shows that precise control of dual doping sites can lead to enhanced electrocatalysis.
A team of scientists discovered a star with unusually low magnesium and excessive heavy elements, indicating it originated from a disrupted dwarf galaxy. The study provides insight into the chemical evolution of dwarf galaxies and their role in shaping the Milky Way.
Most examined circRNAs form imperfect RNA duplexes that act as PKR inhibitors, but rapid degradation by RNase L triggers PKR activation. CircRNA overexpression reduces aberrant PKR activation in SLE patient-derived cells.
Researchers discovered that bacteria can distinguish themselves from closely related competitors through the use of a virus. A novel phage, SW1, controls formation of a demarcation line by utilizing one of the host's cryptic prophage proteins, providing conditional benefits to E. coli K-12.
A team of scientists has identified a novel lignin gene, Zm4CL1, that controls the maize bm5 mutant with reduced lignin content. The study reveals increased forage digestibility and cell wall saccharification efficiency in the bm5 mutant.
Scientists have developed a room-temperature liquid metal-based super-stretchable sensor with high repeatability, low cost, and great stretchability. The new device was tested with excellent performance, showing the great potential for application in flexible wearable electronic devices.
A recent study synthesizes advances in the causes and formation mechanisms of severe haze pollution in northern China. Researchers found that seasonal emissions from residential heating and efficient secondary aerosol formation contribute to severe haze events.
Researchers at Chinese Academy of Sciences develop CRISPRed wheat with tolerance to sulfonylurea, imidazolinone, and aryloxyphenoxy propionate-type herbicides. The trait offers low-risk weed control for millions of multi-cropping farmers in China.