The study found that H2A.Z promotes H4K20me2 deposition, recruiting ORC1 to license and activate early DNA replication origins. H2A.Z-regulated origins have higher firing efficiency and earlier replication timing compared to other origins.
A new study finds significant increases in sediment flux in the Tuotuo River, a key headwater of the Yangtze River. The research attributes these changes to warming temperatures and enhanced precipitation and discharge capacity. The findings provide valuable insights for water and soil management on the Tibetan Plateau.
A team of researchers in China has developed a new algorithm to compare metagenomes, allowing for more accurate understanding of microbiome diversity. The Dynamic Meta-Storms (DMS) algorithm compares metagenomes at the species level, considering physical and genetic details, as well as evolutionary relationships.
Researchers have discovered a new alginate lyase in a heat-loving bacterium that can directly utilize brown algae and ferment its components into ethanol with high-yield. The study has identified previously unknown enzymatic families contributing to bioconversion, shedding light on sustainable seaweed-based biofuel production.
Researchers have proposed new concepts for in situ formed and artificial SEIs to fundamentally modulate the electrochemical characteristics of zinc. The interfacial design enables reversible and dendrite-free Zn plating/stripping, resulting in excellent cycling stability with negligible capacity loss.
A study published in PNAS found that humans are driving the loss of biodiversity among narrow-ranged plant species in China, while widespread species are thriving. The research revealed that human impact factors lead to a negative correlation with narrow-ranged species and a positive correlation with widespread species.
Scientists developed a novel self-powered e-skin capable of inducing a neural response, which can be controlled by photo illumination. The technology has potential applications in quantifying neural plasticity changes and developing novel neural-stimulation systems.
A Chinese research team has developed a new technique that enables super-resolution microscopy of living cells with unprecedented speeds and resolutions. The approach, which combines ghost imaging and compressive imaging, can capture processes in living cells on millisecond time-scales with spatial resolution of tens of nanometers.
The study ranked Asian Water Towers as the most important and most threatened globally, with the Indus water tower being the most relied-upon and vulnerable. Climate change and geopolitical factors pose significant risks to these systems, threatening the water supply for 1.9 billion people.
A study published in Nature Astronomy found 19 dwarf galaxies dominated by baryons at radii beyond their half-optical radius, challenging standard galaxy formation models. The results encourage a reevaluation of dark matter's nature.
The new species Origolestes lii, a stem therian mammal from the Early Cretaceous Jehol Biota, provides evidence for the separation of hearing and chewing modules. The discovery bridges the morphological gap between transitional and definitive mammalian middle ear evolution.
Researchers developed a remote-controlled 'smart' platform to mimic natural extracellular matrix-mediated endothelialization. The platform uses shape-memory polymers and gold nanorods to direct programmed vascular endothelium remodeling in a temporally controllable manner, offering new possibilities for treating cardiovascular disease.
A new species of multituberculate mammal, Jeholbaatar kielanae, has been discovered with a distinct middle ear that suggests specialization for feeding. The fossil provides solid evidence of the morphology and articulation of middle-ear bones in multituberculates.
A new study reveals that animal-like embryos existed 609 million years ago, long before the emergence of definitive animals. The research found that Caveasphaera fossils displayed stages of development similar to those seen in living animals, including humans.
A Chinese-led team of international scientists has discovered a massive stellar black hole with a mass 70 times greater than the Sun, located 15 thousand light-years from Earth. The discovery challenges current models of stellar evolution and forces theorists to re-examine how such massive black holes can form.
Researchers characterized the light-harvesting system of Chlamydomonas reinhardtii, a common unicellular green alga. The study reveals the assembly mechanisms and energy transfer pathways of the C2S2M2L2 supercomplex, shedding light on efficient light harvesting in green algae.
Researchers discovered that an extract from ginseng can induce Enterococcus faecalis, which produces myristoleic acid to activate brown adipose tissue and reduce adiposity. Increasing BAT activity could be a novel therapeutic approach for obesity and related diseases.
Researchers discover avian predentary was covered by keratinous beak, mobile and proprioceptive, representing a unique feeding adaptation. The finding sheds light on the evolution of bird skull structure.
Scientists at Chinese Academy of Sciences create highly stable and coke-resistant Ni SAC, overcoming in situ catalyst deactivation. The unique capacity for selective activation of CH4's first C-H bond explains the intrinsic coke resistance.
Researchers have developed a new type of fluorescent carbon dot that can effectively detect calcium levels in cells. The CDs exhibit bright blue fluorescence and have been shown to be nontoxic and biocompatible, making them a promising probe for intracellular Ca2+ detection.
Researchers have discovered evidence of beetle pollination in Cretaceous Burmese amber, confirming a key contributor to the Cretaceous radiation of angiosperms. The discovery extends the history of insect pollination of flowering plants by around 50 million years.
New study highlights significant advances in phloem-insect/pathogen interaction understanding, but notes research gaps and barriers to study. Researchers propose integrating phloem-feeding insect/pathogen interactions into plant science for improving host resistance.
Researchers at Shenyang Institute of Automation develop contact aerial manipulator system for safe and efficient high-rise building inspection. The robot can avoid obstacles, jump over grooves, and conduct interactive operations while in flight.
Researchers have developed a new assembly that enhances photodynamic inactivation of bacteria, achieving significantly improved efficiency against gram-negative E. coli. The assembly combines a photosensitizer and a membrane-intercalating peptide, resulting in nearly 0% survival rate of E. coli upon light irradiation.
China's coal-fired power plants met ultra-low emission (ULE) standards early, reducing annual emissions by 65% for sulfur dioxide and 72% for particulate matter. The country achieved these results thanks to its strict supervision system and nationwide ULE technology application.
Researchers at Chinese Academy of Sciences develop strategy to stabilize isolated metal atoms on oxide supports using ionic liquids as electronic stabilizer. The method improves catalytic performance and dispersion state of Pt1 and Pd1 catalysts.
China's annual carbon emissions growth declined significantly from 10% to 0.3% between 2002-2012 and 2012-2017, respectively. The slowdown is attributed to China's focus on high-quality development, improving energy efficiency, and shifting consumption patterns.
Researchers discover DEPDC5, a chromosome 22q-targeting tumor suppressor, silenced by mutations in GISTs. The gene's inactivation promotes GIST cell proliferation and reduces sensitivity to KIT inhibitors.
A new cell-material feedback platform enables versatile production, analysis, and purification of diverse proteins and protein complexes on demand. The technology utilizes microbial swarmbots with stimulus-sensitive polymeric microcapsules to facilitate efficient production and analysis.
A study reveals that fungal types and accumulation rates mediate tree-neighborhood interactions, driving species coexistence in subtropical forests. The findings suggest a key role for pathogenic fungi and mutualists in shaping diversity patterns.
Researchers have created a platinum nanoreactor that enables visual detection and mass spectrometry fingerprinting of metabolic biomarkers, allowing for biopsy-free diagnosis of pancreatic cancer patients. The platform has shown sensitivity and specificity of 84% and 92%, respectively.
A research team led by LI Chunlai reconstructed the landing trajectory and positioning techniques of China's Chang'E-4, which successfully landed on the Moon's far side in January. The reconstruction provides valuable insights into the navigation process and could aid future lunar missions.
Researchers have created a two-species microbial consortium to improve the performance of biophotovoltaics, generating a power density of 150 mW·m-2. The system can stably operate for over 40 days, setting a new record for BPV longevity and power output per device.
A new interferometric single-molecule localization microscopy, called Repetitive Optical Selective Exposure (ROSE), has been developed to improve the precision of nanostructure imaging. ROSE achieves a two-fold improvement in localization precision compared to conventional methods.
A 550-million-year-old fossil found in China reveals that mobile and segmented animals evolved by the terminal Ediacaran Period, providing crucial evidence for the origin of segmentation. The discovery also helps scientists understand the producers of Ediacaran trace fossils.
Scientists discovered that viruses alter host plant immunity to deter non-vector insect herbivores, facilitating disease transmission. Geminivirus infection redistributes plant metabolites, inhibiting herbivore growth and production.
Researchers proposed a new type of plasmonic surface lattice resonance (SLR) supported by metal-insulator-metal arrays, which exhibit higher quality factors in less symmetric dielectric environments. This allows for diverse applications, including ultrasensitive sensing and nanolasers.
Scientists have found that rising carbon dioxide concentration in the air enhances land carbon sink, a process known as carbon dioxide fertilization. For every 100-ppm increase in CO2, terrestrial carbon sink increases by 0.64 billion tons of carbon per year globally.
Researchers have developed a new electrolyte regulation strategy for Li-O2 batteries using hydrophobic silica colloidal particles. The strategy prevents lithium dendrite growth and corrosion, achieving a 980-times better anticorrosion effect and stable long-life electrochemical performance.
A team of astrophysicists discovered a connection between the brightening of pulsar wind nebula and the spin-down rate transition in PSR B0540-69. The study found that the X-ray PWN around PSR B0540-69 increased by 32% over 400 days, indicating a sudden enhancement of the magnetic field that powers the pulsar wind.
A new index developed from the skin microbiome of children can identify eczema and predict treatment response. The Microbial Index of Skin Health (MiSH) achieved high accuracy in identifying skin conditions across different cities, paving the way for precise skin care.
A recent study found that water availability in soil determines the direction of carbon-climate feedback, with land carbon uptake increasing below optimal moisture levels and decreasing above them. This discovery provides new insights into the complex relationships between climate change, ecosystem dynamics, and water availability.
Researchers have identified a genetic suppressor of flp stomatal defects, which acts downstream from core cell cycle genes to ensure terminal division during stomatal development. The study found that CDK-mediated phosphorylation at the N-terminus of RPA2a is essential for RPA functioning and localization.
A new study published in PNAS reveals that the northern tropical dry trend may be a result of natural climate variability rather than human activities. The research team analyzed stalagmite records from southern Thailand and found millennial-scale decreases in regional rainfall, similar to other records from the northern tropics.
A novel soft robot with color-changing capabilities has been developed by mimicking the chameleon's skin cells. The robot can sense its environment and exhibit dynamic color change in response. Its unique properties make it suitable for sensing, communication, and disguise in soft robotics.
Researchers have developed a biochemical approach to control the conversion of natural gas into liquid fuel, overcoming challenges in selective hydroxylation of methane and propane. This method uses an artificial P450 system driven by hydrogen peroxide, showing comparable or better catalytic properties than known enzymes.
The China Lunar Exploration Program (CLEP) has accomplished significant advancements in lunar research since its launch in 2007. The program plans to send the first sample-return mission to Earth, dubbed Chang'E 5, and establish a Lunar Scientific Research Station by 2030.
A team of Chinese and Canadian scientists developed a theoretical model to predict properties of hydrogen nanobubbles in metal using computer simulations. The model reveals simple rules for hydrogen trapping behavior in nanovoids, providing a powerful tool for evaluating hydrogen-induced damage in fusion reactors.
A recent study found that lower microbial abundance and aggregate protection are coexisting mechanisms underlying lower Q10 in subsoil, while substrate quality and mineral protection play less role. Microbial communities regulate depth-associated variations in Q10 in the active carbon pool, whereas aggregate protection controls it in t...
Scientists developed a tumor-activatable antibody nanoparticle to overcome immunological tolerance in tumors. The nanoparticle releases PD-L1, triggering tumor antigen release and CTL infiltration, leading to efficient antitumor immunity and long-term immune memory effects.