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Hefei Institutes of Physical Science, Chinese Academy of Sciences


New immobilization strategy enables reliable surface plasmon resonance analysis of membrane proteins

Researchers developed a novel immobilization strategy for surface plasmon resonance (SPR) assays of membrane proteins, effectively addressing technical constraints. The approach allows stable and specific capture of membrane proteins on sensor chips, enabling precise quantification of binding kinetics.

New deep learning model enhances roadside air pollutant forecasting accuracy

A new deep learning model, DSTMA-BLSTM, significantly enhances roadside air pollutant forecasting accuracy by 30% compared to conventional LSTM models. It achieves R² values exceeding 0.94 across major pollutants and demonstrates stable performance under complex traffic-meteorological coupling conditions.

SourceHefei Institutes of Physical Science, Chinese Academy of Sciences·JournalEnvironmental Modelling & Software·DateNov 6, 2025

SHMFF users reveal a new mechanism for abnormal voltage attenuation of P2-type layered oxide cathodes

A research team at Hefei Institutes of Physical Science discovered a new mechanism for abnormal voltage attenuation in P2-type layered oxide cathodes. The study found that accumulation of unreduced molecular O2 leads to structural degradation and performance loss, highlighting the importance of bulk modification strategies.

Researchers improve marine aerosol remote sensing accuracy using multiangular polarimetry

A study improves marine aerosol remote sensing accuracy using multiangular polarimetry, which increases the degrees of freedom for signal (DFS) by at least 1.02 with added shortwave infrared measurements. This leads to the retrieval of one to two additional aerosol parameters and enhances understanding of columnar volume concentration,...

Plasma strategy boosts antibacterial efficacy of silica-based materials

Researchers developed a novel two-step plasma strategy to create surface-functionalized silver/mesoporous silica composites with strong antibacterial activity and positive surface charge. The modified materials showed improved interaction with bacterial membranes and effective suppression of E. coli infections.

Asymmetric stress engineering of dense dislocations in brittle superconductors for strong vortex pinning

Researchers developed an innovative approach to create dense dislocations in brittle superconductors, leading to a five-fold increase in critical current density. The technique utilizes asymmetric stress fields and scalable extrusion technology to induce localized lattice slip and twisting.

Researchers advance in heavy-duty robotics and intelligent control for fusion reactor maintenance

Researchers developed a novel robotic joint for heavy-duty robotics, achieving an ultra-high reduction ratio and delivering torque with low backlash. A deep reinforcement learning-based method also solved the problem of precise peg-in-hole assembly in radiation environments.

SourceHefei Institutes of Physical Science, Chinese Academy of Sciences·JournalEngineering Applications of Artificial Intelligence·DateNov 4, 2025

Engineered membraneless organelles boost bioproduction in corynebacterium glutamicum

Researchers successfully engineered liquid-liquid phase separation-driven membraneless organelles (MLOs) in Corynebacterium glutamicum, resulting in a 2.43-fold increase in indigoidine titer. The technology enables spatial isolation of antimicrobial peptides, reducing toxicity and enabling successful expression.

SourceHefei Institutes of Physical Science, Chinese Academy of Sciences·JournalSynthetic and Systems Biotechnology·DateNov 4, 2025

New integrated method boosts accuracy of blood near-infrared spectroscopy quantitative analysis

Researchers developed an integrated method to accurately measure hemoglobin levels using near-infrared spectroscopy, overcoming limitations caused by strong water absorption and sample scattering. The approach significantly reduced background noise and achieved high accuracy, making it a reliable tool for non-invasive blood analysis.

SourceHefei Institutes of Physical Science, Chinese Academy of Sciences·JournalBiomedical Signal Processing and Control·DateSep 25, 2025

High-symmetry gradient-doped Nd:YAG crystal enhances dual-end pumped laser performance

Researchers developed a high-symmetry gradient-doped Nd:YAG laser crystal that reduces temperature differences between the center and ends, resulting in higher output power and improved beam quality. The crystal showed a 14 W output with efficiency boosted by more than half, making it suitable for dual-end pumping configurations.

Solar-powered system produces green hydrogen directly from air moisture

A team of researchers developed a self-sustaining solar-powered system that produces green hydrogen by coupling photothermal atmospheric water harvesting with proton exchange membrane electrolysis. The system maintains stable performance even under low humidity conditions, reaching a hydrogen production rate of nearly 300 mL per hour.

Generative framework proposed for ecological soundscape analysis

A team developed a method using generative adversarial networks (GANs) to learn underlying patterns in real spectrograms and reconstruct species-specific vocal components. This approach captures hidden features of the acoustic space, enabling precise separation of target sound sources and effective removal of environmental noise.

SourceHefei Institutes of Physical Science, Chinese Academy of Sciences·JournalMethods in Ecology and Evolution·DateSep 25, 2025

High-durability hydrogel electrolyte boosts quasi-solid-state zinc-ion battery performance

Researchers developed a high mechanical durability hydrogel electrolyte using urea as a zincophilic solubilizer, allowing for stable Zn stripping/plating in a dendrite and passivation-free manner. The material enhances the battery's overall performance and retention over time.

SourceHefei Institutes of Physical Science, Chinese Academy of Sciences·JournalAngewandte Chemie International Edition·DateAug 29, 2025

New multi-omics study uncovers key RNA-driven network behind colorectal cancer progression and immune resistance

A multi-omics study identified a key RNA-driven network behind colorectal cancer progression and immune resistance. Restoring a specific long non-coding RNA (lncRNA) expression reactivated tumor suppressor genes and enhanced immune cell infiltration, promoting anti-tumor effects.

Novel model optimization algorithm developed to improve robustness of near-infrared spectroscopy models

Researchers developed a novel model optimization algorithm named External Calibration-Assisted Screening (ECA) to enhance the prediction robustness of Near-Infrared Spectroscopy (NIRS) quantitative models. ECA rapidly adapts initial models to new detection environments by calibrating them with externally collected samples.

Scientists uncover magnetic-field control of ultrafast spin dynamics in 2D ferromagnets

Researchers found that 7-tesla magnetic fields accelerate demagnetization by 60% while suppressing efficiency by 34%, enabling widespread ultrafast demagnetization in other materials. Elevated temperatures enhance regulatory effects, promising real-world applications in high-speed storage and logic devices.

Engineered composite materials offer broad-spectrum synergistic radiation shielding

Researchers developed novel PbWO4 filler-reinforced B4C/HDPE composites with tunable microstructures, achieving enhanced synergistic radiation shielding performance. The optimized composite achieved a 97.32% shielding rate against ²⁵²Cf neutrons and 76.43% against ¹³⁷Cs gamma photons.

SourceHefei Institutes of Physical Science, Chinese Academy of Sciences·JournalComposites Part A Applied Science and Manufacturing·DateJul 9, 2025

AI language models show promise in predicting liver cancer treatment outcomes

A recent study has shown that large language models (LLMs) can accurately predict liver cancer treatment responses, offering a new path towards AI-powered precision medicine. The LLMs demonstrated predictive accuracy on par with senior doctors, while outperforming junior and mid-level clinicians in speed and accuracy.

New strategy developed to engineer high-affinity receptor-containing antibodies against malaria

Researchers have engineered high-affinity antibodies against malaria by incorporating domains from inhibitory receptors, allowing them to block the interaction between parasite proteins and host immune cells. This new strategy offers a promising approach for treating malaria and could lead to innovative antimalarial drug discovery.

Iodine-stabilized single-longitudinal-mode laser enhances atmospheric sensing and environmental monitoring

A compact all-solid-state CW SLM laser with high frequency stability was developed using iodine-based frequency locking, advancing its application in atmospheric remote sensing and environmental monitoring. The laser achieves long-term frequency stability with a drift of 4 MHz over a continuous 7-hour period.

New strategy suggested to boost performance of all-solid-state ion-selective electrodes

Researchers propose a novel strategy to improve all-solid-state ion-selective electrodes by designing transduction layer materials with high hydrophobicity and large capacitance. The study reveals that ion-selective membranes constrain capacitive material performance, hindering sensor reliability.

Advanced aerogel composite developed for extreme environments

Researchers at Hefei Institutes of Physical Science developed advanced aerogel composites with high-temperature insulation and mechanical load-bearing capabilities. The composites achieved controllable fabrication of large-size samples and demonstrated strong potential for future thermal protection applications.

SourceHefei Institutes of Physical Science, Chinese Academy of Sciences·JournalJournal of Materials Research and Technology·DateJul 7, 2025

Low-temperature plasma technique boosts nanozyme innovation for tackling antibiotics

Researchers developed CoNi-MOF nanozymes with laccase-like activity using a gas-liquid interface dielectric barrier discharge (DBD) low-temperature plasma (LTP) technique, exhibiting high catalytic degradation of tetracycline. The novel approach offers an eco-friendly strategy for addressing antibiotic pollution in the environment.

SourceHefei Institutes of Physical Science, Chinese Academy of Sciences·JournalJournal of Hazardous Materials·DateJul 7, 2025

High-performance 3D-printed graphene composites developed for efficient ice control

A research team at the Chinese Academy of Sciences has developed high-performance 3D-printed graphene composites with improved thermal and electrical conductivity. The composites achieved an in-plane thermal conductivity of 4.54 W/(m·K) and showed enhanced photothermal conversion efficiency.