Researchers found that combining CAP and PAW leads to a synergistic effect, increasing fungicidal efficiency. The mechanism involves damage to cell wall and membrane structure via ·OH and O2, followed by irreversible damage to mitochondria with ONOO- entry.
Researchers developed a simulation software to study radiation damage accumulation mechanisms in nanocrystalline materials. The results showed improved radiation resistance due to high grain boundary density, which serves as sinks for radiation-induced vacancies and self-interstitial atoms.
Researchers at Hefei Institutes of Physical Science, Chinese Academy of Sciences, have discovered a potent and selective colony stimulating factor 1 receptor kinase inhibitor. The new compound, IHMT-CSF1R-833, shows high selectivity over human kinases and suppresses tumor-associated macrophage survival and activation.
Scientists have successfully assembled linear metal nanoclusters using a novel strategy. The Ag-Cu alloy clusters exhibit spin transfer and distance-dependent spin coupling due to the interaction with sulfur ions. These findings open up new avenues for understanding nanocluster magnetism and developing functional materials.
Researchers at Hefei Institutes of Physical Science found that a novel mutant, low grain weight (lgw), affects grain size by regulating GW7 expression and cell elongation. The discovery sheds light on the molecular mechanisms controlling grain size in rice.
Researchers developed a nanopore-based method to detect microbes in immunocompromised cancer patients with high sensitivity, identifying bacterial infections, fastidious pathogens, and co-infections. The method reduces turnaround time to approximately 17.5 hours, enabling prompt diagnosis and timely treatment.
Researchers found that protein disulfide isomerase (PDI) regulates radio sensitivity through mitophagy, promoting tumor growth and metastasis. PDI inhibits mitophagy signaling by blocking the interaction of LC3II-PHB2, leading to increased mTOR pathway activation.
A new AI framework, M2YOLOF, has been proposed for fast and high-precision target detection. The framework reduces model complexity and inference time overhead by using a multi-input single-output approach.
A recent study has identified key factors influencing the eating quality of hybrid rice, including single-grain composition and physicochemical indicators. The research developed a novel technology to analyze these traits, enabling rapid and nondestructive detection of high-quality rice.
Researchers from Hefei Institutes of Physical Science developed a novel focusing quadrupole ion funnel to enhance PTR-MS sensitivity, increasing it by 13.8-87.9 times compared to conventional drift tubes. The FQ-IF also improved detection limits for volatile organic compounds.
Researchers found that introducing Ag9AlSe6 nanoparticles into N-type Bi2Te3.7Se0.3 improves thermoelectric performance by enhancing phonon scattering and reducing thermal conductivity. The composite sample exhibits a maximum ZT value of 1.2 at 423K, outperforming the original BTS alloy.
Physicists from Hefei Institutes of Physical Science successfully developed an effective calculation method for the ITER large-caliber magnetic field immunity testing system. The study revealed a novel formula to determine the allowable deviation of equipment coil, providing a theoretical basis for actual installation.
Researchers developed a high-sensitivity differential Helmholtz photoacoustic cell, achieving a minimum detection limit of 177 ppb in methane gas detection. The optimized cell structure and signal processing techniques improved performance by suppressing noise and enhancing photoacoustic signals.
A new type of spectrometer capable of simultaneous remote sensing of atmospheric methane, water vapor, and nitrous oxide has been developed. The spectrometer uses a micro-electro-mechanical system (MEMS) modulator to replace traditional mechanical choppers, making the system more stable and compact.
Researchers have found a novel topology-correlation interplay in an iridate superlattice-based system, leading to anomalous Hall effects and giant magnon gaps. This discovery could provide valuable insights for investigating topology-related physics in other correlated materials.
Researchers create novel material with dual pH sensitivity to deliver hydrophobic pesticide, showing excellent foliar adhesion performance and stability in various conditions. The system displays controlled release behavior, reducing loss and improving utilization rate.
The study investigates three pyrite-type IIB-VIA2 dichalcogenides with promising thermoelectric performances. The researchers found that localized high-frequency optical phonons and soft phonon modes contribute to low thermal conductivities and excellent electrical transport properties, leading to enhanced thermoelectric performance.
Researchers have discovered a way to electrically control the exchange bias effect in FePS3–Fe5GeTe2 van der Waals heterostructures. By introducing protons into the interface, they were able to switch the exchange bias effect on and off. The findings have significant implications for the development of spintronics devices.
Researchers create a new kind of nanozyme that can be triggered by near-infrared light to kill cancer cells through a synergistic cascade mechanism. The nanozyme generates hydroxyl radicals and oxidative stress, enhancing the therapeutic effect of chemodynamic therapy.
Researchers from Hefei Institutes of Physical Science developed a new method using a semiconductor optical amplifier to enhance the signal-to-noise ratio and improve the precision of atmospheric CO2 column measurements. The novel approach, published in Optics Letter, has great potential for remote sensing of atmospheric greenhouse gases.
Researchers identified two distinct stromal cell subsets in mouse lymph nodes, CD41+ Lyve1+ and CD41+ Lyve1-, with different functions. The CD41+ Lyve1- subset provides a microenvironment for immune cell interaction, while the CD41+ Lyve1+ subset is recycled throughout the body to replenish the subset in the lymph nodes.
A new type of filter capacitor is developed using structurally integrated carbon tube grids, achieving high frequency response performance and volumetric capacitance. The capacitors are expected to be used in electronic circuits for AC line-filtering, providing a solution to the limitations of traditional aluminum electrolytic capacitors.
A team from Hefei Institutes of Physical Science developed high-performance electrocatalytic nitrogen to ammonia (N2RR) catalysts by modifying metallic rhodium with dodecanethiol. This approach enhances NRR selectivity and performance, offering a promising alternative to the Haber-Bosch process.
Researchers at Hefei Institutes of Physical Science, Chinese Academy of Sciences developed an active and smart Terahertz electro-optic modulator based on VO2 film. The device achieved near-perfect antireflection and 180o phase switching, enabling accurate THz amplitude control.
Researchers developed a high-efficiency MK-7 synthetic strain using a bottom-up approach, improving synthesis efficiency and reducing by-product formation. The recombinant bacteria achieved 53.07 mg/L MK-7 production, surpassing native Bacillus subtilis 168.
Researchers used high-throughput sequencing to investigate the relationship between microorganisms and internal mildew in sunflower seeds. They found that Alternaria is the predominant mildew-causing pathogenic fungus and that low humidity conditions during storage can inhibit its growth.
A research team developed a multi-emitting europium metal organic framework fluorophore for the visual detection of gallic acid in tea and fruit juice. The probe exhibited high sensitivity, fast response, and low detection limit, making it suitable for practical samples.
Scientists have developed a novel single-atom-kernelled nanocluster catalyst that enhances the efficiency of carbon dioxide conversion. The catalyst, obtained through an 'anti-galvanic reaction' method, shows improved catalytic activity and selectivity compared to traditional methods.
Researchers developed a new method using cold atmospheric plasma (CAP) to treat atopic dermatitis, a chronic inflammatory skin disease. CAP inhibited skin inflammation, reduced symptoms and improved skin conditions in AD mice.
A team of scientists investigated the Cl-initiated oxidation of methacrolein (MACR) under NOx-free conditions, revealing key species and reaction pathways. The study found that MACR reacts with Cl atoms to form C4H5O and C4H6OCl radicals, which then react with O2 to produce peroxy radicals.
A novel method called On The Fly (OTF) accelerates Monte Carlo shielding simulation, making it applicable for complex fusion reactors. The OTF method achieved remarkable acceleration effects of 13 to 20 times compared to existing variance reduction methods.
Researchers developed a spectroscopic method to evaluate astaxanthin isomers' antioxidant activity against singlet oxygen. The study found that the 1O2 quenching capacity of cis-astaxanthin was significantly higher than all-trans astaxanthin, offering new insights into astaxanthin's practical application in the food industry.
FastGC-PTR-MS technology successfully separates and detects butanol isomers in latex paint, with tert-butanol concentration below maximum allowable limit
A team of scientists developed a new Surface-Enhanced Raman Spectroscopy (SERS) method that captures target molecules in small gaps, increasing sensitivity by 2-3 orders of magnitude. The method uses a multilayer nanoparticle film with natural gaps less than 3 nm, allowing for trace dynamic detection and monitoring of biological systems.
Researchers discovered that circVAPA modulates the miR-377-3p and miR-494-3p/IGF1R/AKT axis to promote SCLC progression. CircVAPA depletion enhances the inhibitory effects of an IGF1R kinase inhibitor, providing a potential therapeutic strategy.
Researchers have proposed a novel algorithm, InResSpectra, to accurately identify crop varieties using near-infrared spectroscopy. The model achieved high accuracy in identifying wheat and rice varieties, providing an effective method for authentic identification.
A team of scientists at the Hefei Institutes of Physical Science have fabricated ultrasensitive biosensors based on Surface-enhanced Raman Spectroscopy (SERS) to detect the PD-L1 biomarker. The probes were found to be highly sensitive and specific, allowing for the quantification of PD-L1 as low as 4.31 ag/mL.
A recent study found a honeycomb structure composed of oxygen-poor pores and surrounding net-like branches, which may become a nucleation point for pitting corrosion. The formation process was linked to low dissolved oxygen concentrations in the coolant.
Researchers used infrared and Raman spectroscopy to identify lysine acetylation features, providing a theoretical basis for protein acetylation structure analysis. The study found distinct vibrational spectral characteristics for each acetylation type, enabling accurate identification of acetylated lysine.
Researchers developed a rapid detection method for Arf6 GEF activity using 1D 19F NMR-based approach. The new strategy allows for the monitoring of conformational changes in sGTPases and detecting regulatory protein activities in physiological and pathological environments.
Scientists have developed a new method to synthesize stable diamane under high pressure, which can be used in two-dimensional electronic devices. The researchers found that doping with boron and nitrogen atoms enhances the stability of diamane at ambient conditions.
Scientists from Hefei Institutes of Physical Science, Chinese Academy of Sciences, found that Oct4A is the key factor in maintaining tumorigenic activity of glioblastoma stem cells. Palmitoylation mediated by ZDHHC17 preserves Oct4A protein stability and facilitates Sox4-Oct4A complex formation.
Researchers developed an interpretable radiomic model to predict radiotherapy treatment response in patients with brain metastases. The model, combining radiomics and SHAP methods, demonstrated good performance and interpretability.
A new nanosensor developed by Chinese scientists can detect mesna, a regional antidote for urinary system protection, in real-time with high sensitivity and selectivity. The platform features an upconversion-based sensor that eliminates background interference and offers a simple and reliable strategy for clinical drug monitoring.
A novel enzyme-free strategy was developed to detect organophosphorus pesticide residues like glyphosate in agricultural products. The new approach uses a ratiometric fluorescence sensor that can visualize and quantify glyphosate residues with high sensitivity, allowing for rapid detection and monitoring of pesticide residues.
Researchers found that low-energy helium plasmas pre-exposure creates nanostructures on material surfaces, reducing deuterium plasma-driven permeation flux. Theoretical calculations confirm that surface protrusions and near-surface helium bubbles reduce hydrogen isotope penetration through the material.
Researchers from Hefei Institutes of Physical Science found that singlet oxygen plays a crucial role in synergistic antimicrobial mechanism with other ROS generated by cold atmospheric plasma. This study improves understanding of fungicidal mechanism and provides theoretical guidance for applications of plasma technology.
Researchers developed zinc oxide/graphene oxide nanocomposites to detoxify cadmium poisoning, which competitively inhibited cellular Cd uptake and promoted Cd excretion. The compounds showed excellent detoxification capacity and biosafety, holding promise for treating occupational exposure populations.
A study found that silver nanowire films with better plasticity exhibit stronger shear fracture resistance. Adding an ultra-thin metal buffer layer can improve the films' stability without affecting their optical properties.
Researchers fabricated a nano-ruler with high spatial resolution to explore the longitudinal plasmonic field in nanocavities. The study found an unexpectedly large intensity gradient, shedding new light on understanding of plasmonics and SERS technology.