Researchers at IU School of Medicine will use advanced neuroimaging techniques to study high school athletes and understand the impact of concussions on brain blood flow. The study aims to improve understanding of concussion symptoms, cognitive functioning, and detection methods.
A recent study found that nearly half of hospitalized adults aged 65 and older require assistance making decisions due to cognitive impairment. Family members or children often fill this role, with significant implications for patient care and outcomes.
A new IU study explores social learning dynamics and finds that being surrounded by copycats can lead to better problem-solving success. The researchers created a virtual problem landscape using a computer game and found that imitators often make their own improvements, which are then adopted and improved upon by others.
Delirium in older patients is frequently overlooked due to the lack of screening tools in emergency departments. The condition can lead to prolonged hospital stays, increased mortality rates, and a higher risk of developing dementia. Researchers call for the development of emergency department-specific screening instruments to improve ...
A study found that cognitive training can benefit older adults for up to 10 years, improving their ability to conduct everyday tasks. The training was effective in reducing difficulty with tasks such as using the phone, tracking medication use, and managing finances.
A new study finds that heavy viewers of 'Teen Mom' and '16 and Pregnant' have unrealistic perceptions of teen mothers' quality of life, income, and involved fathers. The research, led by Indiana University professors, suggests that these shows lead to a distorted view of reality TV and teen parenthood.
Researchers have identified a key protein, GCN5b, necessary for the Toxoplasma parasite to replicate, offering new targets for drug therapies. Disabling this complex halted parasite replication, suggesting its potential as a treatment for toxoplasmosis and malaria.
Researchers discovered the largest example of horizontal gene transfer in any organism, where <i> Amborella </i> acquired foreign genes from green algae and other plants. The study provides insight into the evolution of mitochondrial fusion and its role in horizontal gene transfer.
Researchers found that retinoblastoma protein malfunction enables TGF-β to stimulate pancreatic cancer cell proliferation. Abnormal pathways activated by TGF-β and Wnt7b can be disrupted with drugs, providing potential therapeutic targets.
A novel role for S100β has been identified as a biomarker for delirium duration in critically ill patients, which may have implications for refining treatment in intensive care units. Delirium duration is associated with increased mortality rates, and higher levels of S100β on day 1 or day 8 are linked to longer delirium duration.
A study analyzing 5.5 million research papers and 27.3 million authorships found that female authors were underrepresented, receiving fewer citations than their male counterparts. The findings highlight the need for policies to address systemic inequalities in science, particularly through international collaborations.
A team of researchers at Indiana University has successfully detected peptidoglycan in the bacterial cell wall of Chlamydiae, a common target for antibiotics. The discovery could lead to new strategies for developing drugs against this leading cause of STD and other diseases.
A new study from Indiana University and Brazil's Oswaldo Cruz Foundation found that indigenous hunting with fire maintains ecological integrity and sustains vegetation recovery in areas previously deforested by agribusiness. This practice effectively manages carbon emissions over the long term.
Researchers found significant differences in brain white matter between varsity football and hockey players and non-contact-sport athletes. The study suggests that repeated blows to the head without concussions may cause cognitive decline, warranting further investigation into identifying susceptible athletes.
Researchers analyzed minute movements to diagnose autism and determine its severity in children and young adults. The study found that fluctuations in hand movements can indicate the degree of autism spectrum disorder, allowing for subtyping and improved diagnosis. This breakthrough may lead to more tailored treatments.
The Radiological Society of North America (RSNA) and the Regenstrief Institute are collaborating on a project to harmonize and unify terms for radiology procedures. The goal is to produce a single unified source of names and codes for radiology procedures, promoting common understanding, simplifying clinical processes, and enhancing da...
Researchers unveil an immersive digital experience of Hadrian's Villa, featuring interactive exploration and historically accurate avatars. The virtual world simulation combines scholarly studies with cutting-edge technology to recreate the ancient site.
A study by Indiana University and Regenstrief Institute found that cognitively impaired older adults released from the hospital are less likely to be rehospitalized within 30 days if they go to a nursing home. In contrast, those returned to their own homes or family members are more likely to experience readmission.
A study published in Medical Care found that high-volume ERCP providers had lower failure rates and hospitalization rates compared to low-volume providers. The authors suggest establishing quality improvement guidelines and credentialing processes to improve patient outcomes.
The Child Health Improvement through Computer Automation (CHICA) system has improved autism screening rates by identifying at-risk children at the 24-month visit. This personalized and automated patient screening process prompts pediatricians to follow up in needed areas, leading to timely diagnosis and treatment.
A study by Regenstrief Institute and Indiana University found that older adults with severe mental illness have a higher rate of medical emergency department visits and longer hospital stays. The study highlights the need for more intensive care models that consider psychosocial factors.
A study by Indiana University cognitive scientists reveals that 1-year-olds and their parents coordinate visual attention to objects through hand-eye coordination, rather than just following gaze. This new mechanism has implications for language learning and the treatment of children with early social-communication impairment.
A study found a disconnect between public health campaigns promoting STI testing and actual conversations between lovers, particularly among college-age individuals. Conversations about STIs can influence behavior and decision-making, but many participants reported limited discussions or no testing.
A new strategy using a 'ditty bag' of condoms and lubricants, along with homework assignments, improves condom use among young men who have sex with men. The study found increased motivation to use condoms correctly and consistently, as well as better fit-and-feel issues.
A new study by Indiana University researchers found that access to healthcare in counties with more dentists and pharmacists is associated with higher rates of opioid abuse. The study concludes that the structure of local healthcare systems plays a key role in determining community-level access to opioids.
Residents in a low-income urban neighborhood on Indy's east side have higher rates of diabetes, hypertension, and heart disease compared to other areas. The study suggests that limited access to healthy food contributes to these health disparities.
A lack of state-level coordination and organization is hindering efforts to address cervical cancer, according to a new Indiana University study. The researchers identified numerous obstacles, including a paucity of inter-agency influence and a failure to establish streamlined systems of care.
A new paper by Tim Lemper argues that the Supreme Court's decision in National Federation of Independent Business v. Sebelius established new limits on Congress' power to regulate commerce and use federal funds to coerce states. The court's decision placed groundbreaking limits on federal regulation, setting a precedent for future cases.
Researchers at Indiana University have developed a molecule combining GLP-1 and GIP peptides, which shows improved therapeutic effects in controlling glucose levels and weight loss. The study demonstrates the potential of this combination as an effective treatment for adult-onset diabetes and obesity.
A new study found that higher-ranking group members manipulate perceived threats to preserve their rank, while average individuals may underestimate real threats. This study highlights the dark side of cooperation and self-sacrifice in groups.
The OPTIMISTIC study, a healthcare initiative from Indiana University and the Regenstrief Institute, is underway in 19 Central Indiana nursing facilities. The program focuses on improving care coordination, palliative care, and chronic disease management to reduce avoidable hospitalizations.
Researchers analyzed conversations between chronic pain patients and their physicians about opioid treatment, revealing three patterns of physician responses: reassurance, avoidance, and gathering information. The study emphasizes the crucial role of a strong therapeutic alliance in discussing risks and benefits of opioid treatment.
A recent study using dental fossils suggests that the common ancestor of Neanderthals and modern humans diverged nearly 1 million years ago, contradicting previous molecular evidence. The researchers found no known hominin species matches the expected dental morphology of the last common ancestor.
A special issue of Preventive Medicine explores common misconceptions about the HPV vaccine, including concerns about sexual disinhibition and vaccine safety. Studies show that these fears are largely unfounded, and that the vaccine can help prevent cervical cancer and other HPV-associated cancers.
IU researchers and collaborators found two new targets, Rac GTPase and Pak, that can be inhibited to kill leukemia cells. The study aims to improve treatment options for patients with mast cell leukemia and acute myeloid leukemia.
Research attributes high smoking rates among mentally ill to brain susceptibility to addiction, not self-medication. The study found that psychiatric disease makes the brain more vulnerable to nicotine addiction, which has severe health consequences.
A new Indiana University study found that preterm birth is strongly linked to infant and young adult mortality, autism, and ADHD. However, it also suggests that other associated issues, such as severe mental illness and economic woes, may be related to shared family factors rather than preterm birth itself.
A new study uses a computer-based decision support system to deliver personalized evidence-based recommendations for pediatricians, increasing the likelihood of accurate ADHD diagnoses. The system, CHICA, also prompts physicians to screen for anxiety and depression.
A newly discovered role for a protein family could provide a path to modifying crop traits. The discovery reveals that this protein regulates gene expression in response to light color changes, potentially allowing for new approaches to trait modification in agriculturally significant plant species.
Researchers at Indiana University have developed a novel vaccine that effectively reduces the shedding of genital herpes virus, potentially providing a new treatment option for those affected. The vaccine, GEN-003, is one of the first to target viral shedding, which is often how the disease is spread.
Researchers have identified the ancient ancestor of the tulip tree line, which diverged from magnolias over 100 million years ago. The discovery sheds light on the evolution of this iconic Eastern North American species.
A new study found that Minnesota's Performance-based Incentive Payment Program improves critical areas of nursing home care, including falls, quality of life, and rehospitalizations. The program promotes local solutions to local problems and focuses on provider-initiated and evidence-based practices.
Researchers at Indiana University found that asexual lineages are more susceptible to extinction due to fast-paced gene conversion processes. This process exposes pre-existing deleterious recessive mutations, contributing to the decline of asexual populations.
A study published in Molecular Psychiatry found RNA biomarkers in blood associated with suicidal thoughts in patients with bipolar disorder. The researchers identified SAT1 and other markers that were significantly elevated in the blood of both bipolar disorder patients and those who had committed suicide.
A study found that surrogate decision-makers consider both the patient's interests and their own needs when making medical decisions, highlighting the complexity of this process. The researchers suggest greater advance care planning to address this issue.
A study by Indiana University found that higher-performing elementary school students received more diverse and abundant resources from their parents, including extracurricular activities and networking opportunities. Lower-performing students, however, only received targeted resources to improve their academic performance.
An Indiana University study analyzed 537 million tweets to find a correlation between the number of tweets about a candidate and their vote count. The research suggests that social media behavior can be used as an indicator of real-world political behavior, providing a new tool for analyzing election outcomes.
A new study by Indiana University found that student loan debt significantly affects college students' experiences, leading to three distinct categories: play-hard, disengaged, and serious students. Students with debt tend to prioritize social life over academics, while those without debt live a more balanced lifestyle.
Researchers have produced detailed descriptions of human folate receptor proteins, aiding in the design of new drugs that can target cancer cells without harming healthy ones. The findings could lead to effective treatments for ovarian cancers and inflammatory diseases such as rheumatoid arthritis.
A new study by Indiana University found that schools implementing coordinated school health programs saw increases in students' physical activity levels. The programs included before- and after-school walking programs, classroom activity breaks with physical activity, and club sports.