Researchers identified a single genetic mutation in the CUBN gene linked to albuminuria, a condition indicating kidney disease, in both diabetic and non-diabetic individuals. The study's findings have significant implications for understanding the mechanisms behind kidney disease and potentially leading to novel treatment targets.
A dry powder, live-attenuated measles vaccine was successfully tested in rhesus macaques, providing complete protection with a single dose. The novel vaccine can be shipped as powder and does not require reconstitution or special training to administer.
Researchers at Johns Hopkins Bloomberg School of Public Health found that black obese patients receive less weight-related counseling than white obese patients, regardless of the doctor's race. This disparity is particularly concerning given the increased risk of chronic diseases associated with obesity among blacks in the US.
A study published in the Journal of the American Medical Association found that prenatal iron-folic acid supplementation boosted children's cognition in Nepal. The research showed a positive association between maternal supplementation and improved general intellectual ability, executive function, and fine motor control.
A study by Johns Hopkins Bloomberg School of Public Health found that Indonesian children who watched Jalan Sesama, a local version of Sesame Street, showed significant improvement in literacy, math skills, safety knowledge, and social awareness compared to those with low exposure.
A study by researchers at the Johns Hopkins Bloomberg School of Public Health found that youth generally perceive community street outreach workers positively, regardless of personal experience. The majority of respondents reported successfully resolving conflicts and needing help with employment, education, and healthcare needs.
A new study found that parents have a limited impact on their children's eating habits, with complex factors like schools and peer influence playing a significant role. Researchers analyzed worldwide studies to conclude that correlations between parent-child dietary intakes have become weaker over time.
A new study by Johns Hopkins researchers reveals a large burden of syphilis infection and high-risk behaviors among male clients of female sex workers in Sichuan province. The study found that 30% of these males practiced consistent condom use, highlighting the need for effective interventions to prevent HIV transmission.
A geriatrician calls for improvements to primary care to meet the needs of older adults with multiple chronic conditions. Four processes and three models were identified as effective in providing comprehensive support, improving health outcomes, and patient satisfaction.
Hospitalizations for ATV injuries among US youth increased by 150% over a nine-year period, with significant increases seen in the South and Midwest. The study found that females ages 15 to 17 experienced the sharpest rise in ATV hospitalizations, despite males having the highest rate.
The Center for Injury Research and Policy at Johns Hopkins Bloomberg School of Public Health will conduct multi-center studies on treatment and outcomes of major orthopedic injuries. The expansion aims to establish treatment guidelines and improve outcomes for wounded warriors.
A computer model shows that the US is susceptible to MDR-TB epidemics when TB prevalence falls and case detection improves, even with high treatment compliance. This is attributed to the increased risk of drug-resistant TB spreading in populations with low drug-susceptible TB rates.
A new software, Myrna, uses cloud computing to analyze RNA sequencing data at an unprecedented speed and cost-effectiveness. The software calculated differential expression from 1.1 billion reads in under 2 hours for a cost of around $66.
Researchers reviewed data to assess immune responses to vaccines in HIV-infected children on HAART. Most children responded well to revaccination, but those with poorer immune systems and slower immune reconstitution may require additional doses to maintain protective immunity.
A new study by Johns Hopkins researchers finds that street outreach workers are a crucial tool for preventing and intervening in youth violence. The program, run by the United Teen Equality Center (UTEC), incorporates elements like peacemaking, resource provision, and community partnerships to achieve success.
Overweight American children and adolescents have experienced a significant increase in adiposity measures over the last decade. The study found that heavier children gained more abdominal fat, posing greater health risks than elevated BMI, particularly among black girls.
A new report from Johns Hopkins Bloomberg School of Public Health finds that trauma center care is cost-effective for patients with severe injuries and those younger than 55. The study estimates that trauma center care saves lives at a lower cost per life-year gained compared to non-trauma center care.
A new study by the Center on Alcohol Marketing and Youth found that youth exposure to alcohol advertising in magazines declined by 48 percent between 2001 and 2008. The largest brands still advertising in youth-oriented publications were those selling spirits.
A new study reveals falls as the leading cause of non-fatal injuries among older adults in China, with 70% of injuries occurring at home or on the street. The divorced and widowed elderly are identified as high-risk groups for injury, highlighting the need for targeted prevention programs.
A community-based maternal health delivery strategy known as the MOM Project increased access to maternal health care services for internally displaced women in eastern Burma. The study found a ten-fold increase in women assisted at delivery by emergency obstetric care workers, resulting in improved antenatal and postnatal care outcomes.
Physicians who provided Guided Care reported higher levels of satisfaction with patient/family communications and knowledge of their patients' clinical characteristics. The study found significant benefits to physicians in improving chronic care, including reduced costs and improved health outcomes.
A six-week intervention with Kilimani Sesame content significantly improved cognitive, social and health outcomes in Tanzanian children. The study found that increased exposure to the program led to higher scores on literacy and math tests, as well as greater knowledge about HIV/AIDS and malaria.
A study analyzing pro-eating disorder websites found that most were publicly accessible and featured calorie calculators. The sites also promoted eating disordered behaviors, such as extreme exercise and purging.
Researchers found that mortality rates were significantly lower among patients who received DOT from a nominated treatment supporter compared to self-monitored ART. The study suggests that social capital and emotional support provided by these supporters contributed to improved survival outcomes.
A new study published in The Lancet found that common blood tests for kidney function and urine protein levels can predict mortality risk. People with high levels of albumin in their urine were at a higher risk of mortality, with an increased risk of nearly 50% at certain thresholds.
Researchers found that biological differences between men and women can impact vaccine efficacy, with women typically generating a more robust protective immune response. This knowledge could inform strategies for optimizing vaccination programs, including the timing and dose of vaccines.
Vitamin A supplementation before, during, and after pregnancy significantly improved lung function in preadolescent children. Children whose mothers received vitamin A had a greater forced expiratory volume and vital capacity compared to those who received beta-carotene or placebo.
Preventable infectious diseases are the leading causes of child mortality worldwide. According to a new study published by The Lancet, these diseases are responsible for two-thirds of nearly 9 million child deaths globally in 2008. The analysis reveals that global efforts must be targeted to have maximum impact.
The Johns Hopkins Bloomberg School of Public Health has received a $100,000 Grand Challenges Explorations grant to develop an evolution-proof pesticide that could prevent malaria. The project aims to use a virus to instruct the mosquito to die after transmitting the malaria parasite, reducing the risk of resistance.
Survivors of Cyclone Nargis continue to face challenges in accessing relief and reconstruction efforts, with basic rights remaining unmet. Community-based organizations play a crucial role in responding to disasters in challenging settings like Burma.
Researchers found comparable obesity rates in white and black women living in similar social conditions. The study suggests that socioeconomic status and environmental factors play a significant role in explaining obesity disparities. Policies focusing on modifying social aspects of the environment may help reduce disparities among low...
A study published in Nature Genetics has identified four genes, including MAFB and ABCA4, linked to cleft lip and/or cleft palate. The genome-wide association study involved 1,900 families from diverse ancestry groups, revealing new insights into the causes of this congenital malformation.
African children with sickle-cell disease are at increased risk of bacterial illness, especially invasive pneumococcal disease. Vaccines against pneumococcus can improve quality of life and save lives among these vulnerable children.
A global study of over 65,000 individuals has identified more than a dozen genes associated with chronic kidney disease. The researchers found that common genetic variations in these genes were more frequent in people with poor kidney function or chronic kidney disease.
The Teen Years Explained: A Guide to Healthy Adolescent Development dispels myths about teens' behavior, physical changes, and risk-taking. The book emphasizes the importance of sleep, nutrition, and parental influence on adolescent development.
Significant increases in death rates from falls, motorcycle crashes, machinery use, and unintentional poisoning have been observed among older Americans. The overall change in injury mortality for individuals aged 65 years and older increased by three percent, with the greatest increase seen in whites.
A new study by Johns Hopkins researchers examines the potential influence that business connections between broiler chicken growers may have on the transmission of avian influenza, H5N1. The study found company affiliation to be the greatest driver of farm-to-farm disease transmission risk.
The Johns Hopkins Bloomberg School of Public Health will receive nearly $15 million in funding to renovate and modernize its laboratory space, enhancing its research capabilities. The grant supports the update of outdated facilities, including the 45-year-old Hume Wing, which houses 25% of the school's research laboratories.
Researchers analyzed data from 147 countries from 1990-2007 and found that receipt of GAVI support accelerated Hib vaccine adoption by 63%, while neighboring countries' use accelerated it by 50%. High vaccine prices hindered adoption, with lack of stable financing policies having a more detrimental effect.
Researchers found that HbA1c levels accurately predict future diabetes and stroke, heart disease, and all-cause mortality. The study identified people with HbA1c levels between 5.0 to 5.5 percent as within the normal range, while those at a level of 6.5 percent or greater are considered diabetic.
A study by researchers at Johns Hopkins Bloomberg School of Public Health suggests that mosquitoes played a primary role in spreading West Nile virus westward across the US. Genetic analysis detected widespread movement by Culex tarsalis populations, which were congruent with the pattern of West Nile virus infection across the country.
A new report by Johns Hopkins Bloomberg School of Public Health found that 66 percent of Marylanders without advance medical directives may face deficiencies in end-of-life care across the US. The results indicate a disconnect between what people want for their medical decisions and their actions to ensure those preferences are carried...
Chronic illness patients supported by nurse-physician teams rate primary care as significantly higher than usual care recipients. Guided Care improves coordination with specialists, self-management support, and goal-setting assistance.
A retrospective evaluation led by researchers at Johns Hopkins Bloomberg School of Public Health recommends improvements for scaling up child survival programs. The study found that coverage for effective treatment interventions and addressing causes of neonatal deaths and undernutrition are crucial for accelerating child survival.
A new study found that rural males are 47% more likely to die from injuries than their urban counterparts, while rural females face a 33% higher risk of injury-related mortality. The disparity is attributed to various factors such as unintentional suffocation in infants and suicide among older adults.
Researchers found that higher antiretroviral therapy adherence was associated with lower direct health care costs for HIV-infected adults in South Africa. This decrease in costs is largely attributed to reduced hospital use, saving a median monthly health care cost of $85 per patient.
A new strain of antibiotic-resistant tuberculosis has been identified as thriving in the presence of rifampin, a front-line drug. The bacteria grew poorly without rifampin and worsened with treatment regimens containing the drug, but recovered once rifampin was removed from the regimen.
Participating in social service activities like tutoring children can delay or reverse declining brain function in older adults. The study found that seniors made gains in key brain regions supporting cognitive abilities, improving daily life planning and organization.
A recent study found that more than 1,013 US patients are admitted to hospitals each year with aviation-related injuries, including lower limb fractures as a common injury among passengers and parachutists. The study highlights the need for improved aircraft design to prevent these injuries.
Despite concerns about decreased physical activity contributing to rising obesity rates, research suggests that physical activity levels may actually be increasing among US adolescents. While minority students and girls are less active than their peers, sedentary behaviors like screen time remain a concern.