MIT researchers have found a new way to create solid particles of highly concentrated antibodies, suspended in a solution, which can be injected using a standard syringe. This advance could make antibody treatments more convenient and accessible for patients, particularly older people with difficulty visiting hospitals.
A new robotic design uses vine-like structures to lift and grasp a variety of objects, including humans, with a gentler approach. The robot can snake around obstacles, squeeze through tight spaces, and even secure itself in a closed loop to create a sling.
Researchers at MIT have identified three clusters of pragmatic skills that are based on the same kinds of inferences and may have similar underlying neural processes. These skills include interpreting social conventions, understanding physical world knowledge, and distinguishing between tones to convey emphasis or emotion.
MIT researchers analyzed a recently discovered Pompeii construction site to shed new light on ancient Roman concrete, which has endured for thousands of years. They found that hot-mixing was indeed used by the Romans, contradicting ancient texts and providing valuable insights into a material with self-healing properties.
A new study identifies a practical and powerful prognostic marker that can help clinicians tailor treatment strategies to improve survival for patients with aggressive T-cell lymphoma. Researchers found that patients who relapse within 12 months of initial therapy have a dramatically declining chance of survival, making targeted therap...
New research by MIT researchers found that even with the same CO2 reduction, air travel causes about three times more damage to air quality than comparable electricity purchases. The study highlights the importance of considering co-pollutants and regional factors when evaluating climate actions.
The MIT team developed a new AI-based controller that enables the robot to follow gymnastic flight paths, such as executing continuous body flips. The robot's speed and acceleration increased by 450% and 250%, respectively, compared to previous demonstrations, making it comparable to insects in terms of agility.
Researchers developed instance-adaptive scaling framework that uses process reward model to estimate difficulty of question, enabling LLMs to spend more compute on promising solution paths. This approach achieves comparable accuracy with existing methods while reducing computational cost by up to one-half.
MIT chemists successfully synthesized verticillin A, a fungal compound that has shown potential as an anticancer agent. The researchers then generated derivatives of the compound and tested them against pediatric brain tumors, finding that some were effective against cancer cells with high levels of EZHIP protein.
A study by MIT researchers examines two policy approaches to expanding the US electricity grid: one focusing on regions with more renewable energy sources and another creating more interconnections across the country. The study found that a geographically unbalanced grid buildout would be less expensive, while reducing carbon emissions...
Researchers at MIT have developed a shoebox-sized device that can measure blood glucose levels using Raman spectroscopy, potentially replacing finger pricks for people with diabetes. The device's accuracy is similar to that of commercially available continuous glucose monitoring sensors.
MIT engineers developed artificial tendons made from hydrogel to connect lab-grown muscles with robotic skeletons. The tendons improved the robot's motion and force output by three times, enabling faster and more efficient biohybrid robots.
Large language models can learn to mistakenly link certain sentence patterns to specific topics, causing unexpected failures on new tasks. This shortcoming could reduce the reliability of LLMs used in safety-critical domains like handling customer inquiries and generating financial reports.
Researchers used NASA's IXPE telescope to study the innermost region of an intermediate polar, revealing a surprisingly high degree of X-ray polarization and an unexpected direction of polarization. The team found that X-rays were emitted from a column of white-hot material pulled in by the white dwarf's strong magnetic field.
Researchers developed a new approach called SEAL that enables large language models (LLMs) to update themselves permanently. This allows LLMs to learn from user input and improve their performance on tasks like question-answering and pattern-recognition. The technique improves accuracy and enables smaller models to outperform larger ones.
Researchers at MIT used CT scans to study 5,000-year-old slag waste from an ancient site in Iran, revealing fine details about structures within the pieces. The technique complements traditional methods of studying ancient artifacts, shedding light on materials used and technological sophistication of early metallurgists.
The algorithm identifies the minimum set of locations where field studies would guarantee finding the least expensive route, considering problem structure and uncertainty. This method can be applied to broad classes of structured decision-making problems under uncertainty.
MIT engineers have developed an ultrasonic device that vibrates at high frequency to shake out water molecules from a material, recovering clean drinking water in minutes. This design is 45 times more efficient than existing heat-based systems, which can take hours or days.
Researchers at MIT have developed a nearly impermeable polymer film that could protect solar panels and infrastructure from corrosion. The film, made using a solution-phase polymerization reaction, completely repels nitrogen and other gases, outperforming existing polymers.
Researchers have developed particles that can deliver an effective immune response at a much lower dose than traditional mRNA vaccines. The new particles, called AMG1541, use cyclic structures and ester groups to enhance mRNA delivery and improve biodegradability. This could potentially reduce vaccine costs and side effects.
Researchers have discovered new evidence of unconventional superconductivity in magic-angle twisted tri-layer graphene, a material that exhibits exotic electronic behavior. The team found that the material's superconducting gap looks very different from typical superconductors, suggesting a unique mechanism for its emergence.
Researchers at MIT have identified possible antigens for a new TB vaccine, stimulating a strong immune response in T cells. The study reveals 27 TB peptides that appear most often on infected cell surfaces and elicit a T cell response in at least some samples.
A new study by MIT researchers and their collaborators at national laboratories quantifies I-129 release under three different scenarios: direct disposal in deep underground repositories, dilution and release, and filters to capture I-129. France's practice of reprocessing releases 90% of I-129 into the biosphere, while U.S. approach l...
Researchers at MIT developed microscopic, wireless bioelectronics that can identify and travel to specific brain regions without human guidance. These implants provide focused treatment for brain diseases like Alzheimer's and multiple sclerosis by wirelessly powering electrical stimulation in precise areas.
MIT engineers have developed a programmable drug-delivery patch that can reduce damaged heart tissue by 50 percent and improve cardiac function. The patch is designed to release different drugs at specific times, promoting healing and regeneration of cardiac tissue.
A new physics-based approach predicts how lightning strikes aircraft, identifying vulnerable regions for protection. The tool can be applied to any shape of aircraft, including unconventional designs.
The new tool, called FSNet, combines machine learning and optimization to find feasible solutions quickly while ensuring constraints are met. It can unravel complex problems several times faster than traditional solvers and even outperform pure machine learning approaches.
MIT researchers use messenger RNA to activate an immune pathway in nearby immune cells, triggering the destruction of tumors. The approach combines existing immunotherapy drugs and avoids side effects associated with large doses of STING activators.
MIT researchers have developed new nanoparticles that deliver the immune-stimulating molecule IL-12 directly to ovarian tumors, eliciting a strong response and clearing tumors in over 80% of mice. This treatment combines with checkpoint inhibitors to launch an attack on cancer cells without causing side effects.
A new study reveals that laws restricting pain clinics, or 'pill mills,' where opioids were often prescribed, reduced risky opioid use by 5 percent. Enacting such laws near the onset of the crisis in the 1990s could have reduced risky use by 30 percent over time.
A new study by MIT researchers suggests that literacy screenings may not be effective due to inadequate teacher training and suboptimal testing conditions. The survey of over 250 teachers found that many lacked sufficient training, leading to difficulties in administering and interpreting the tests.
Researchers found that sleep-deprived individuals experience attentional failures coinciding with a flushing of CSF from the brain. During these lapses, physiological changes occur, including a flux of CSF out and then back in. The study suggests that the brain attempts to compensate for lost cleansing by initiating pulses of CSF flow.
Researchers developed a new method to probe an atom's nucleus using its own electrons as messengers within a molecule. They measured the energy of electrons whizzing around a radium atom in a molecule, detecting a slight energy shift and analyzing it to sense the internal structure of the nucleus.
A new computational method, DIGIT, enables optical microscopes to resolve individual atoms and zero in on their exact locations in a crystal structure. This technique can help guide the design of quantum devices and provide insights into advanced materials.
A study by MIT researchers found that design elements of data visualizations influence viewers' assumptions about the source of the information and its trustworthiness. Readers make these assessments primarily from design features like color palette or arrangement, rather than underlying data, often unintentionally by designers.
Researchers used a new high-resolution mapping technique to find small 3D loops connecting regulatory elements and genes that persist during cell division. These loops strengthen when chromosomes become more compact, potentially helping cells 'remember' interactions from one cell cycle to the next.
Researchers from MIT and the MIT-IBM Watson AI Lab have introduced a new training method that enables vision-language models to localize personalized objects in a scene. By using carefully prepared video-tracking data with contextual clues, the model is better able to identify the location of a specific object in a new image.
Researchers developed a technology to detach cells from surfaces on demand, reducing waste and improving workflow in industrial processes. The system uses electrochemically generated bubbles to separate cells without damaging them, paving the way for more efficient CO2 absorption and lifesaving cell therapies.
A new study by MIT researchers evaluates the scale-up potential of over 16,000 quantum materials, finding that those with high quantum fluctuation in electrons tend to be more expensive and environmentally damaging. The team identified promising candidates with an optimal balance between quantum functionality and sustainability for fur...
Researchers at MIT have developed a new system that allows for precise control over the expression of synthetic genes in cells. The DIAL system uses a promoter editing mechanism to establish desired protein levels, which can be edited after delivery. This technology has the potential to improve gene therapy and cell reprogramming appli...
A new AI tool, SpectroGen, uses generative AI to quickly assess material quality by generating spectra in less than one minute. It can replace traditional methods that take several hours or days, improving productivity and efficiency in industries such as manufacturing and pharmaceuticals.
Researchers at MIT have developed a new method to improve the stability of optical atomic clocks by reducing quantum noise and stabilizing a laser. The approach, known as global phase spectroscopy, doubles the precision of an optical atomic clock, enabling it to discern twice as many ticks per second compared to traditional setups.
Researchers at MIT have found a hidden atomic order in metals that changes their properties, including mechanical strength and heat capacity. The discovery reveals a new physical phenomenon explaining the persistent patterns and provides a simple model to predict chemical patterns in metals.
Researchers at MIT have developed a new way to engineer CAR-NK cells that are less likely to be rejected by the patient's immune system, making them a promising treatment for cancer. The cells can destroy most cancer cells while evading the host immune system, and may offer a better safety profile than traditional CAR-T cells.
Researchers at MIT have developed a 3D-printable aluminum alloy that is five times stronger than traditionally manufactured versions. This breakthrough could lead to lighter and more efficient aircraft parts, such as fan blades in jet engines, reducing energy consumption and costs.
Scientists at MIT developed a method to predict how plasma in a tokamak will behave during rampdown, achieving high accuracy with limited data. This new model could significantly improve the safety and reliability of future fusion power plants.
MIT researchers develop a new type of fluorescent molecule that can emit and absorb light in the red to near-infrared range, potentially enabling clearer images of tumors. The stabilized borenium ions have high quantum yields, making them suitable for biomedical imaging applications.
MIT researchers developed a new framework that helps engineers design complex systems explicitly accounting for uncertainty. The framework allows them to model the performance tradeoffs of a device with many interconnected parts, each of which could behave in unpredictable ways. This approach can help engineers develop complex systems ...
The Graffiti framework enables users to create personalized social apps that serve communities' needs, promoting healthier online interactions. With its flexible structure and decentralized infrastructure, Graffiti allows users to migrate between applications without losing their data or connections.
MIT researchers have developed a new model that explains lithium intercalation rates in lithium-ion batteries. The model suggests that lithium intercalation is governed by coupled ion-electron transfer, which could enable faster charging and more controlled reactions.