A pilot study by Mayo Clinic researchers found that flaxseed therapy decreased hot flashes in postmenopausal women by 50% and improved their quality of life. The study also showed improvements in mood, joint pain, and overall health.
The study found that women who had both ovaries removed but were treated with estrogen until age 50 did not have an increased risk of cognitive impairment or dementia. Women who had one or both ovaries removed before menopause faced a higher long-term risk of cognitive impairment or dementia compared to those who retained their ovaries.
Mayo Clinic researchers have discovered a new diagnostic test to detect infection in prosthetic joints, which samples bacteria adhering to the prosthesis surface. The new method detected more infected cases (78.5%) than conventional tests (60.8%), offering improved treatment options and patient outcomes.
Researchers discovered B7-H3, an immune molecule that predicts prostate cancer progression and recurrence after surgery. The biomarker can help individualize treatment plans for patients.
Reactivating a key gene, sFRP-1, has been shown to stop tumor growth and reduce metastasis in clear cell renal cell carcinoma. The study found that sFRP-1 controlled 13 tumor-promoting genes along the Wnt signaling pathway, which is linked to various cancers.
A recent study published in Mayo Clinic Proceedings found that patients prescribed cholesterol-lowering medications do not necessarily adopt unhealthy diets. Despite taking statins, patients made good faith efforts to improve their health through lifestyle changes.
A preliminary study of 85 patients with bipolar disorder shows that modafinil can improve depressive symptoms, with 44% of participants reporting improved symptoms and 39% experiencing remission after six weeks.
Mayo Clinic physicians found that obese patients who received an obesity diagnosis were more likely to form a weight loss management plan than those without a diagnosis. The study highlights the importance of proactive discussion between physicians and patients about obesity, a risk factor for diabetes and cardiovascular diseases.
A Mayo Clinic-led collaborative study finds that focused ultrasound treatment of uterine fibroids offers sustained symptom relief and durable outcomes. The more complete destruction of tumors by focused ultrasound results in improved quality of life and lower incidence of severe side effects.
A new therapy, certolizumab pegol, has been found to be effective in easing symptoms of patients with active Crohn's disease. The treatment was shown to improve clinical symptoms in both short-term and long-term maintenance therapies, offering a potential new option for managing the condition.
Mayo Clinic physicians have developed a new technique using real-time 3-D ultrasound to block nerve function in selected areas of the body prior to surgery. This allows patients to recover faster and with less need for pain medication. The technique has been successfully used in over 150 surgeries, showing improved outcomes for patients.
A study by Shinshu University Graduate School of Medicine found that high-intensity interval walking may protect against high blood pressure and decreased muscle strength in older adults. Walking is a legitimate mode of exercise that doesn't require special equipment or membership, according to Dr. James Levine.
A recent study published in the Journal of Clinical Oncology found that women with atypia in their breast tissue are nearly eight times more likely to develop breast cancer. The study, led by Mayo Clinic, improved risk prediction by taking into account age at diagnosis and multiple sites of atypical hyperplasia.
Researchers found that mice without CD38 were protected from high-fat diet-induced obesity and glucose intolerance. The study suggests that a CD38 deficiency has a protective effect against obesity, highlighting the importance of genes in regulating body weight.
A new study from Mayo Clinic researchers reveals that the joint effects of common DNA variations in several genes within a well-defined biological pathway largely explain why some people develop Parkinson’s disease. The findings also predict with great accuracy at what age people might develop their first symptoms.
Four-year data from two large clinical trials found that trastuzumab significantly improves disease-free survival and overall survival rates in women with HER2-positive breast cancer. The study showed a 52% decrease in the risk of disease recurrence and a 35% reduction in mortality rates compared to chemotherapy alone.
Researchers found vorinostat's anti-cancer activity in patients with recurrent glioblastoma multiforme, with a 15% patient success rate and improved median overall survival. The study aimed to explore the novel application of vorinostat in targeting brain cancer.
A Phase II study has shown that combining chemotherapy drugs with an antiangiogenic agent can significantly delay the spread of tumors in patients with metastatic melanoma. The treatment, which included paclitaxel and carboplatin with bevacizumab, prevented tumor growth for almost six months and improved survival rates.
Researchers at Mayo Clinic have discovered that low doses of gabapentin substantially reduce hot flashes in patients undergoing anti-hormonal treatment for prostate cancer. The study found that gabapentin reduced the frequency and intensity of hot flashes by up to 46% in men receiving androgen deprivation therapy.
Recent studies conducted at Mayo Clinic have found that MRI is superior to mammography in detecting additional tumors in the same breast and identifying new tumors in the healthy breast. The technology has also revealed distinct patterns between ipsilateral and contralateral tumors, guiding its use.
A pilot study by Mayo Clinic researchers found that high-dose American ginseng improves fatigue and vitality in cancer patients. Patients receiving the highest dose showed significant improvements in overall energy levels, mental, physical, spiritual, and emotional well-being.
A recent study by Mayo researchers found that about 40% of patients referred for a second opinion on long QT syndrome (LQTS) did not show sufficient evidence to merit the diagnosis. The study highlights the challenge in diagnosing LQTS, which can be lethal if not diagnosed correctly, and emphasizes the need for cautious evaluation by e...
A Mayo Clinic research team has developed a simple tool to enhance medication adherence in diabetes patients, with 84% of users showing improved compliance. The decision aid sparks conversation between doctors and patients about medication risks and benefits, leading to better-informed decisions.
Researchers at Mayo Clinic have successfully developed a protocol for performing coronary angiography on the same day as elective valve surgery, reducing the need for separate hospital visits and improving patient outcomes. The study, which evaluated 226 consecutive patients, showed that 28.3% had severe coronary artery disease requiri...
Researchers at Mayo Clinic have developed a new imaging technique called magnetic resonance elastography (MRE) to diagnose liver diseases. MRE accurately measures the hardness or elasticity of the liver, enabling non-invasive diagnosis of fibrosis and cirrhosis.
Researchers at Mayo Clinic have discovered a correlation between violent rapid eye movement sleep behavior disorder and eventual onset of parkinsonism or dementia. Patients with the disorder may be exhibiting early signs of an evolving neurodegenerative disease caused by abnormal synuclein protein clumps.
A recent study published in Mayo Clinic Proceedings found that two-thirds of people using herbs do so without following scientific guidelines. The study, which analyzed data from a 2002 National Health Interview Survey, highlights concerns about the potential adverse effects and interactions of herbal supplements with therapeutic drugs.
A study by Mayo Clinic found that adalimumab is an effective treatment for adults with Crohn’s disease who do not respond to infliximab therapy. The therapy was shown to achieve remission in 21% of patients and improve symptoms in 52%.
A new immunosuppression regimen for heart transplant patients has been found to improve kidney function and prevent transplant coronary artery disease. The study, led by Sudhir Kushwaha, used sirolimus as an alternative to calcineurin inhibitors, with consistent improvement in kidney function in stable patients.
Researchers identify mutations in moonlighting enzyme dihydrolipoamide dehydrogenase (DLD) that contribute to the reduction of frataxin production, leading to increased severity of Friedreich's ataxia. The study suggests DLD as a potential target for therapies of this condition.
Researchers found that a miscue in the body's genetic repair system may cause Huntington's disease, a fatal condition that destroys the nervous system. The study revealed that repeated tracts of replacement repair segments become toxic and accelerate cell death.
Researchers at Mayo Clinic have developed a breast cancer vaccine that successfully stimulated an anti-tumor T cell response in female mouse models, slowing or stopping the progression of breast cancer. The vaccine's effectiveness was achieved by combining synthetic peptides with a Toll-like receptor stimulant and anti-CD25 antibodies.
Scientists at Mayo Clinic have isolated an enzyme called SULF2, which appears to be overexpressed in nasopharyngeal cancers. High levels of SULF2 are associated with increased risk of early recurrence and death within 10 years after radiation therapy.
Researchers at Mayo Clinic Cancer Center have discovered that chaetocin, a by-product of common wood mold, is more effective than current therapies in killing multiple myeloma cells. The study found chaetocin induces oxidative stress and selectively kills myeloma cells with superior efficacy.
The new technology significantly improves the accuracy of radiologist interpretation by aligning 3D medical images in three-dimensional space. This enables quicker diagnoses and treatment for patients with diseases like cancer, reducing wait time and anxiety.
A detectable PSA level is first indicator of recurrent prostate cancer after radical prostatectomy, with a doubling time of less than three months indicating imminent death from prostate cancer. Patients with longer doubling times are at significant risk for disease recurrence and cancer-specific death.
Researchers analyzed data from 397 adults and children, finding that most asthma flare-ups led to step-up in medication doses. Fewer patients experienced step-down therapy changes when symptoms subsided, highlighting the need for more flexible treatment approaches for asthma patients.
The article examines the definition of pedophilia, characteristics of offenders, recidivism rates, and potential treatments. Researchers discuss how to determine pedophilic behavior and the impact of mandatory reporting laws on victims and abusers.
Researchers at Mayo Clinic have found that cryoablation is an effective treatment option for patients who are not good candidates for surgery due to size or location of the tumor. The procedure involves freezing the tumor with argon gas, resulting in short-term success in over 90% of selected patients.
Researchers design novel peptide-based drug to lower high blood pressure, targeting B-type natriuretic peptide (BNP) hormone, and create hybrid molecule for treating both heart and kidney impairment in acute heart failure.
A new Mayo Clinic study found that heart patients' likelihood of receiving a drug-eluting stent varies greatly by insurance type, hospital location, and procedural volume. Patients with private insurance are more likely to receive a drug-eluting stent than those with Medicare or Medicaid, while hospitals serving large numbers of Medica...
The FAST TRACK protocol dramatically reduces the time that elapses before patients undergo a life-saving procedure, saving both heart muscle and patient lives. The new system includes key elements such as single-call instant alerts, electrocardiograms within five minutes of arrival, and rapid loading by air ambulance.
A Mayo Clinic study found that using computerized reminders can increase mammography screening rates, with 64.3% of women in the intervention group getting a yearly mammogram compared to 55.3% in the control group. The program has expanded beyond mammograms to include other preventive services.
A study by Mayo Clinic researchers found that normal cell phone use has no noticeable impact on patient care equipment. The five-month test involving 300 calls and 192 medical devices revealed no problems incurred.
Researchers at Mayo Clinic are testing an engineered measles virus against multiple myeloma, a cancer of the bone marrow with no cure. The study aims to exploit the protein CD46 to target and kill cancer cells.
Mayo Clinic researchers successfully transplanted cardiac preprogrammed embryonic stem cells into diseased hearts, regenerating infarcted heart muscle without tumor formation. The study establishes a tumor-resistant approach to growing new heart tissue from an embryonic stem cell source.
A Mayo Clinic study has identified a genetic mutation associated with an inherited predisposition to atrial fibrillation, a type of irregular heartbeat. The discovery may lead to improved identification and treatment of younger patients affected by this condition.
A Mayo Clinic study found a link between dopamine agonist medications and compulsive gambling in RLS patients. The medication-induced behavior worsened with increasing doses, but was reversible when the dose was reduced or alternative medication was used.
The Mayo Clinic team has proposed a system of lung surgery quality indicators to demonstrate best practices for positive patient outcomes. The proposed measures include patient-centered processes prior to, during, and after surgery, such as pulmonary function testing, electrocardiogram, smoking history documentation, and timely pain co...
The Mayo Clinic suggests a reimbursement system based on value rather than traditional pay-for-performance, aiming to improve healthcare quality and reduce spending. The proposed system rewards hospitals for achieving good patient outcomes at lower costs, while penalizing those with worse outcomes.