Research highlights the benefits of omega-3 fatty acids for cardiovascular health, particularly among those diagnosed with coronary artery disease. The consumption of fish oil supplements or algae supplements can provide these essential fatty acids.
Researchers found that Asian Indians have higher insulin resistance and mitochondrial function than Northern Europeans, despite being non-obese. This study suggests that urbanization and diet changes may contribute to the increased risk of type 2 diabetes in Asian Indians.
A Mayo Clinic analysis of autopsy results over two decades reveals a long-term decline in coronary disease has ended, with some data suggesting an upward trend. The study's findings are based on the examination of 515 Olmsted County residents who died between 1981 and 2004.
The US donor organ allocation system, MELD score, and its impact on liver transplant outcomes are discussed. Early referral for liver transplant evaluation is found to offer advantages unrelated to waiting time, including early detection and treatment of liver cancer.
Researchers at Mayo Clinic have developed a new technique using two small flexible tubes to stage lung cancer, achieving a 93% accuracy rate in finding malignant lymph nodes. This method is less invasive and more precise than traditional surgical methods, allowing patients to recover the same day.
Antioxidant supplements were found to have no beneficial effects on reducing cancer risk, while beta carotene supplementation was linked to increased risk of smoking-related cancers. The study also provides practical guidelines for workplace drug screening and concludes that nasal spray flu vaccine is a safe and effective way to preven...
Researchers at Mayo Clinic Jacksonville have identified three genes on chromosome 10 associated with Alzheimer's disease. Blood levels of amyloid beta proteins were significantly elevated in asymptomatic young individuals from extended families, indicating a substantial genetic risk factor.
A new Mayo Clinic study identified several gene variations that predict people at high risk for ALS and Parkinson's disease. The researchers found a high-risk prediction factor for ALS (2,000 times greater than average) and for Parkinson's disease (nearly 400 times greater than average).
A new Mayo Clinic study found that removing the entire kidney from younger patients with small kidney tumors may lead to decreased overall survival. In contrast, partial nephrectomy resulted in a 10-year overall survival rate of 93%. The study's findings highlight the importance of considering long-term health consequences for patients...
Physicians must not participate in executions as it contradicts the core concept of ethics in medicine. Lethal injections used in executions raise concerns about pain and human suffering, with experts calling for improved procedures to ensure humane treatment. The Mayo Clinic Proceedings provides a forum for debate on this critical issue.
Researchers designed a technique that uses the body's own cells and a virus to destroy cancer cells, which could lead to a new cancer vaccine. The study shows promising results in treating melanoma, lung cancer, and colorectal cancer by targeting tumor cells in the lymph nodes.
Researchers found that grade 2 and 3 tumors are more common in HER2+ and triple negative cancers, which have a higher risk of growth and relapse. Cancer came back frequently in these subtypes, with a death rate higher in triple negative breast cancer.
A Mayo Clinic program has reduced delays between abnormal mammograms and diagnosis, improving outcomes for women with cancer. The clinic's multidisciplinary breast clinic helped overcome barriers such as lack of transportation and childcare, providing timely care to underserved women.
Two studies from Mayo Clinic found that ER/PR negative breast cancers have the worst overall outcomes when spreading to the brain, resulting in shorter median survival times. Women with triple negative tumors and HER2+ tumors without estrogen or progesterone receptors have poor outcomes due to aggressive brain metastasis.
A new study published by Mayo Clinic researchers found that Herceptin helps women with HER2+ type of breast cancer independent of whether they have extra copies of chromosome 17. The analysis showed significant benefits for patients with polysomy 17, including a disease-free survival rate of 89% after three years of treatment.
New research from the Mayo Clinic suggests that shingles and its complications may have a greater impact on healthy adults than previously thought. The study found that shingles affects at least 1 in every 278 adults each year, with post-herpetic neuralgia being the most common complication, especially among older adults.
A phase II trial of Cybor-D, a combination therapy including cyclophosphamide, bortezomib, and dexamethasone, showed an improved response rate compared to traditional lenalidomide-dexamethasone therapy. The treatment resulted in a rapid initial decline and percentage reduction in M protein levels.
A retrospective study found a link between erythropoiesis-stimulating agents and leukemic transformation in primary myelofibrosis patients. The research confirmed clinical and laboratory variables associated with leukemia development, including specific treatments that increased the risk of leukemic transformation.
A clinical trial by Mayo Clinic found a lower dose of steroids to be as effective as the standard high-dose treatment in improving overall survival rates for multiple myeloma patients. The new regimen, lenalidomide plus low-dose dexamethasone, showed significantly better results with less toxicity.
A recent study by Mayo Clinic found that relatives of patients with Parkinson's disease are at increased risk for developing depression and anxiety disorders. The risk is particularly elevated in families where the patient develops Parkinson's before age 75.
Researchers at Mayo Clinic have developed a new imaging technology called magnetic resonance elastography (MRE) that can provide images of affected muscles with greater clarity than traditional MRI. This technology measures tissue elasticity and can detect abnormal hardening of tissues, which is a hallmark of myofascial pain syndrome.
A Mayo Clinic study shows cryoablation can provide durable pain relief for patients with bone metastases. Eighty percent of patients experienced significant pain reduction after the treatment, which also improved their quality of life.
A review of 62 Mayo Clinic patients who underwent cryoablation to treat cancerous kidney tumors found that all patients remained cancer-free for up to two and a half years after the procedure. The treatment's effectiveness was demonstrated by the successful elimination of 89 out of 91 tumors in a single treatment session.
Researchers evaluated mycophenolate mofetil to reduce lupus flares in SLE patients and found significant reductions, especially for severe flares. The treatment was effective even with reduced use of anti-inflammatory drug prednisone.
Researchers at Mayo Clinic developed a simple approach to predict heart disease in rheumatoid arthritis patients, finding 85% of those 60-69 year olds had a 1 in 5 chance of developing serious cardiovascular events. The study emphasizes the importance of comprehensive cardiovascular risk assessment for all newly diagnosed patients.
Mayo Clinic researchers will study renal vascular disease caused by atherosclerosis to find new ways to diagnose and treat the condition. The study aims to develop novel imaging tools to predict, detect, and evaluate the disease, with the goal of preventing renal deterioration.
A Mayo Clinic study reveals that over half of heart attack patients discontinue taking prescribed medications within three years. Smokers are more likely to stop taking all their medications in the short term, while those in cardiac rehabilitation programs tend to continue medication at a higher rate than non-participants.
The study found that patients who arrived at the hospital within one to two hours of onset had a 77% higher rate of receiving reperfusion therapy, compared to those who waited 11-12 hours. Delayed arrival resulted in lower rates of reperfusion therapy and poorer treatment outcomes.
Researchers at Mayo Clinic found no link between diabetes treatment and survival rates after a heart attack. The study, which analyzed data from over 2,700 patients, suggests that commonly used medications for managing blood sugar levels do not reduce the likelihood of survival after a heart attack.
A Mayo Clinic study found that modest weight gain in lean, healthy young adults impairs blood vessel function, but shedding the weight restores proper functioning. Visceral fat is a key predictor of this disorder, also known as endothelial dysfunction, which can lead to heart attacks and strokes.
Three anesthesiologists and a medical ethicist discuss whether doctors should participate in state-ordered executions, citing technical problems with lethal injection. They argue that doctors can minimize suffering, but others propose replacing anesthesia-related drugs with alternative personnel.
Mayo Clinic researchers found that 2ME2 can effectively target breast cancer cells, prevent the spread of breast cancer to bone and protect bone from osteolysis. The study's findings suggest that 2ME2 could be a new therapy in treating advanced breast cancer.
A new study by Mayo Clinic researchers found that massage therapy decreases pain levels for patients after heart surgery. In a pilot study of 58 patients, those who received massage had mean pain scores less than 1 on a scale of 1 to 10, compared to an average rating of 3 among the control group.
Researchers at Mayo Clinic Jacksonville found that partial breast irradiation can expose as much lung and heart tissue to potentially toxic radiation as whole breast irradiation. This suggests that both methods carry equivalent risks and benefits.
Researchers at Mayo Clinic Jacksonville have found that tiny radioactive spheres can effectively treat cancer that has spread to the liver, halting tumor growth in 71% of patients. The treatment works by delivering radiation directly to tumors using millions of tiny polymer beads containing yttrium-90.
Researchers found that younger patients with colon cancer have shorter telomeres than expected, suggesting a possible biomarker for early detection. The study also found gender differences in the incidence of colon cancer among young people.
A new Mayo Clinic study presents a chromosome test called 'FISH' as a better method for identifying genetic abnormalities in patients with plasma cell malignancies. This improved analysis may help physicians assess patient prognosis and treatment response more accurately.
A Phase II trial of a new combination therapy for patients with platinum-resistant ovarian cancer showed a 33% overall response rate, twice as high as traditional chemotherapy regimens. The therapy combines flavopiridol and cisplatin and is promising for developing more effective treatments for this disease.
Research suggests viruses like Human Ad-36 may play a role in causing obesity in humans, with evidence showing weight gain and fat storage in infected animals. Studies also found connections between viral infections and obesity in human subjects, including exposure to the Ad-36 virus.
Primary central nervous system vasculitis is a rare and poorly understood disorder that can lead to stroke or death. A recent Mayo Clinic study provides clarification on the methods of diagnosis and treatment, suggesting a combined diagnostic approach using angiography, brain biopsy, and laboratory studies.
Researchers at Mayo Clinic have discovered an antibody that can repair the damaged myelin sheath in laboratory mouse models, a crucial step towards treating multiple sclerosis and related disorders. The antibody promotes remyelination with a single dose, paving the way for potential new treatments.
A literature review published in Mayo Clinic Proceedings finds that many patients with chronic heart failure can engage in sexual activity with proper screening and treatment. The authors analyzed studies on the impact of sexual activity on heart rate and blood pressure, showing moderate oxygen consumption levels comparable to normal d...
A Mayo Clinic review of patients' responses to droperidol found no proven cases of complications directly attributable to the drug's use. The study suggests that alternative medications may not be as effective in controlling nausea and vomiting, leading some anesthesiologists to resume low-dose use of droperidol.
Most diabetes drug trials prioritize reducing blood sugar levels over patient-relevant outcomes like complication risk and quality of life. This can lead to ineffective treatments that cause more harm than good.
Researchers at Mayo Clinic discovered that loss of progranulin gene causes errant splicing of a protein that disrupts normal functioning of neurons. Accumulation of toxic TDP-43 proteins is found in several neurodegenerative diseases, including Alzheimer's Disease and Frontotemporal Dementia.
A recent study suggests that an abnormal amount of inflammatory cells in the duodenum may be responsible for nonulcer dyspepsia, a condition characterized by chronic or recurrent abdominal pain. The researchers propose targeted anti-inflammatory medicine as a potential treatment option.
A Mayo Clinic study of nearly 5,000 children with ADHD found that treatment with prescription stimulants was associated with improved long-term academic success. The study also showed that girls with untreated ADHD were equally vulnerable to poor school outcomes as boys and may be at risk for being undertreated.
Researchers discovered that first-degree relatives of PBC patients have a higher prevalence of anti-mitochondrial antibodies, a biomarker indicative of the disease. This finding enables early screening and assessment of high-risk family members through simple blood tests, potentially leading to better outcomes for PBC patients.
A new Mayo Clinic study published in Value in Health found no significant difference between abciximab and eptifibatide in hospital stay length or cardiovascular event rates. The study provides data to guide treatment decisions for heart patients undergoing angioplasty.
Anesthesiologists and medical ethicist discuss pros and cons of doctors participating in state-ordered executions. Some argue that humane methods can be used to minimize suffering, while others believe it violates the Hippocratic oath and compromises medical professionalism.