The Mayo Clinic has pioneered a novel method of jaw reconstruction for oral cancer patients, utilizing distraction osteogenesis after tumor removal surgery. This approach enables patients to receive both radiation therapy and reconstruction concurrently, minimizing scar tissue and improving patient tolerance.
A Mayo Clinic study found that patients with widely fluctuating blood pressure during the first three hours in the emergency room were much less likely to survive more than 90 days after a stroke. The study suggests that managing blood pressure acutely after ischemic stroke is crucial to improve survival rates.
Researchers at Mayo Clinic have identified two cases of 'broken heart syndrome,' a rare condition that mimics a heart attack, resulting from opioid withdrawal and cocaine use. The findings highlight the importance of cautious medication management and patient education to prevent serious complications.
A study found that REM sleep behavior disorder is a precursor to neurodegenerative diseases such as Parkinson's disease and dementia with Lewy bodies. Patients with RBD are at increased risk for developing these conditions, which can lead to serious consequences like brain hemorrhages and death.
A recent study at Mayo Clinic suggests a strong association between REM sleep behavior disorder (RBD) in younger patients and antidepressant use. The study found that 80% of RBD patients under 50 years old used antidepressants, compared to 15% of those over 50.
A new study by Mayo Clinic researchers found that pesticide use increases the risk of Parkinson's disease in men, with a higher likelihood of exposure compared to women. The study matched individuals with Parkinson's disease to those without, assessing exposure via farming occupation or hobbies.
A Mayo Clinic study found that acupuncture significantly improved symptoms of fibromyalgia in patients, including fatigue and anxiety. The study's results lend credence to the effectiveness of non-traditional methods in improving health.
A recent study has shown that trastuzumab reduces recurrence of HER-2 positive breast cancer by 50 percent and does not add complications to radiation treatment. The study was conducted on 1,460 patients who received radiation in the original N9831 group, with no significant difference in side effects.
The study found that the average time to disease progression was approximately eight months for patients taking dexamethasone alone, while those on the Thal/Dex regimen had an average progression time exceeding 17 months. Researchers also reported more frequent side effects with the combination therapy.
Researchers at Mayo Clinic have found a significant association between acid reflux and esophageal cancer, with patients who experience acid reflux having a 30- to 125-fold increased risk of developing esophageal cancer. The study also discovered susceptibility genes in familial Barrett's esophagus and esophageal cancer.
Researchers identified two genes, CAV3 and RyR2, linked to SIDS. The study found molecular and functional evidence in these genes suggesting a possible explanation for the condition. The findings point to the heart as a critical area of investigation for SIDS.
A new study from the Mayo Clinic contradicts previous research suggesting a link between patent foramen ovale (PFO) and stroke risk. The study found that traditional cardiovascular risk factors are more important than PFOs in causing cryptogenic strokes in older adults, while younger patients may have a higher risk associated with PFOs.
A retrospective study found that closing PFOs and atrial septal defects with transcatheter devices is a safe treatment option for children and young adults who have had a stroke. Most patients remained symptom-free months after the procedure.
Mayo Clinic Proceedings editorial highlights need for further research on PFOs and stroke risk. Additional studies will help determine best course of treatment for patients with PFOs.
A study found that patients with rheumatoid arthritis treated with TNF-blocking antibodies are at a higher risk of developing cancer and serious infections. The drugs, which were previously thought to be safe, may interfere with the body's ability to fight off infection and cancer.
The Mayo Clinic study found that brains of people with mild cognitive impairment showed structural changes similar to Alzheimer's disease, but not as severe. The researchers believe this transitional state may indicate a person is on the road to developing Alzheimer's.
A Mayo Clinic study reveals that comas are often grossly misrepresented in movies, with inaccurate depictions of patients' appearances and care. The researchers propose solutions to improve accuracy in film portrayals, including collaborations between screenwriters and neurologists.
The study found no differences in visual acuity, contrast sensitivity, or perception of stray light between the two types of LASIK. Bladeless LASIK showed greater corneal backscatter initially, but patients perceived no difference in vision after three months.
The Mayo Clinic team has discovered that an echocardiography-guided genetic test can be more effective in identifying hypertrophic cardiomyopathy (HCM) mutations, particularly when combined with unique anatomical features of the heart. This approach can help physicians provide more accurate counseling to families and unlock new researc...
A study at Mayo Clinic found that patients treated with shock wave therapy for kidney stones were at higher risk of developing diabetes and hypertension, with risks nearly four times and one-and-a-half times respectively. The researchers believe the association may be due to damage inflicted on the pancreas or scarring in the kidneys.
A study published by Mayo Clinic researchers found that surgical ovary removal elevates the risk of dementia in younger women, possibly due to insufficient estrogen. Women who underwent the surgery at a younger age may be more susceptible to cognitive decline, highlighting the need for ongoing hormone replacement therapy.
A study by Mayo Clinic researchers found that epilepsy surgery is durable and effective, improving quality of life for patients with intractable epilepsy. The procedure removed the focal region of brain disease in 399 consecutive patients, with a 4% risk of complications.
Research identifies three estrogen-related gene variants associated with an increased risk of Parkinson's disease in women. The study found that these genetic variations affect 10-20% of the female population and could be used to predict disease risk using a simple blood test.
The authors outline a vision for a dynamic learning organizational system to ensure quality care at an affordable price. Key elements include professionalism, systems engineering, and information technology to provide universal coverage through a market-based model with government assistance.
Mild cognitive impairment affects 9% of those 70 to 79 and nearly 18% of those 80 to 89. Education years also impact risk: 25% for up to eight years, 14% for nine to 12 years, and 8.5% for greater than 16 years
The Mayo Clinic research identifies a signaling mechanism by which natural killer cells initiate a toxic response against cancers and viruses. The discovery provides crucial information for designing therapies to stop, reverse or protect against cancer.
Researchers found that waves in cancer cells selectively round up activated growth-promoting proteins, which can help terminate signals and prevent cancerous traits. This discovery provides new insights into the role of waves in cancer cell metastasis.
A Mayo Clinic study found that a specific gene profile of HOXB13 and IL17BR is an independent marker of early breast cancer relapse or death in lymph node-negative breast cancer. This discovery has significant clinical implications, suggesting the potential for improved treatment outcomes for high-risk patients.
A study by Mayo Clinic researchers identified 8 genes with significant under-expression and 3 with over-expression, strongly implicating them in prostate cancer development and progression. The findings suggest that these genes may serve as biomarkers for diagnosing and predicting prostate cancer, potentially improving treatment outcomes.
A study analyzing newspaper articles on neurologic diseases reveals 21% stigmatizing language and 20% medical errors or exaggerations, affecting public understanding and health care coverage. Researchers call for more mindful reporting to improve patient attitudes and overall health outcomes.
Researchers found significant and long-lasting heart benefits for bariatric surgery, including improved body weight, lipid levels, blood pressure, and fasting glucose. The study estimated that the surgery could prevent 16 cardiovascular events and 4 overall deaths per 100 patients compared to the control group.
Researchers at Mayo Clinic are testing a revolutionary classroom concept that promotes increased physical activity among children, using advanced technologies such as standing desks and wearable devices. The goal is to prevent childhood obesity by encouraging kids to move more during learning.
Patients identified seven ideal physician behaviors: confident, empathetic, humane, personal, forthright, respectful, and thorough. Training physicians on interpersonal skills may improve patient outcomes.
A Mayo Clinic study found that patients with rheumatoid arthritis have preserved hearing and are no more susceptible to hearing loss than those without the disease. However, rheumatoid arthritis patients were more likely to perceive they had hearing problems due to their disability level.
A recent study published by the Mayo Clinic found that MPA was more effective than venlafaxine in reducing hot flashes by 79% versus 55%. The single dose of MPA showed long-lasting benefits, with many patients still experiencing a 90% reduction in symptoms after six months.
A study by the North Central Cancer Treatment Group found that reducing epoetin alfa dosing frequency from once weekly to every three weeks did not significantly impact hemoglobin levels or require transfusions. Patients in both treatment groups reported similar quality of life at the end of the 21-week study.
A study published in Mayo Clinic Proceedings found that 22.4% of people with chronic pain did not inform their physician about it, likely due to poor experiences or barriers to healthcare. The study highlights the need for better pain management and increased awareness among healthcare professionals.
Mayo Clinic researchers propose a new understanding of how sepsis arises, suggesting that normal body substances may cause some cases of the deadly condition. They identify a critical receptor that triggers the sepsis cycle, which could lead to new treatments.
The Mayo Clinic study found a significant association between high levels of HtrA1 in placental tissues and severe preeclampsia. The findings may lead to the development of a blood test to track HtrA1 levels, enabling early detection and management of preeclampsia.
The study found that infant transplant patients resisted infections despite having low T cell counts, a crucial component in fighting viruses and cancer tumors. This discovery could lead to improved treatments for AIDS, cancers, and diseases of aging related to declining immune function.
A study of 100 children with chronic daily headache and 100 children with episodic headache found that sleep disturbance was a common issue in both groups. The researchers suggest that addressing sleep problems may help alleviate headaches and prevent the progression from episodic to chronic daily headache.
The study reveals that MDC1 plays a critical role in amplifying distress calls from injured DNA, triggering the repair process. This discovery provides insights into how cancer researchers can design new treatments to manage DNA damage and resist tumor formation.
A Mayo Clinic study discovered a relationship between vertebroplasty and the development of new fractures, with patients' risk for new fractures in adjacent vertebrae being 4.62 times higher than nonadjacent vertebral fractures. The researchers recommend patients considering vertebroplasty be aware of potential long-term risks.
Researchers have identified a key gene involved in Meckel-Gruber syndrome type 3 (MKS3), a rare form of polycystic kidney disease. The discovery provides a breakthrough in understanding the disorder and developing new therapies.
A study published in Mayo Clinic Proceedings found that most snowmobiling injuries in children are caused by ejection, falls or collisions. Education on helmet use, reducing speeds and increasing state regulations can significantly reduce these types of injuries.
A study by Mayo Clinic researchers found that aggressive surgery greatly improves survival rates for patients with the most severe disease spread. Radical surgery was shown to improve five-year survival rates by 44% compared to non-radical surgery, indicating it aids in survival rather than increasing risk.
A study found that nearly half of patients treated with the PC combination experienced a clinical benefit, including stable disease and tumor size reduction. Researchers believe this combination has a beneficial role, especially for patients with poor treatment outcomes.
A Mayo Clinic study found that vertebroplasty significantly improved back pain and activity levels in patients with vertebral compression fractures. Patients' pain during rest and activity improved an average of seven points one week after treatment and remained improved for up to a year.
A recent study by Mayo Clinic researchers found that only about 4.5% of aggressive kidney tumors express KIT, a receptor kinase tyrosine, and no mutations were detected in most cases. This suggests that imatinib therapy may not be effective for these patients, despite previous studies suggesting its potential benefits.
A Mayo Clinic study found that women with a genetic change in the CYP2D6 enzyme are at higher risk of breast cancer relapse when treated with tamoxifen. This genetic variation can also reduce the development of hot flashes, a common side effect of tamoxifen treatment.