Researchers at Mayo Clinic have identified a new type of sleep apnea called complex sleep apnea, which is a combination of obstructive and central sleep apneas. Complex sleep apnea patients often appear to have obstructive sleep apnea but do not fully respond to CPAP machines.
A study by Mayo Clinic researchers found that men who took nonsteroidal anti-inflammatory drugs (NSAIDs) had a 50 percent lower risk of developing an enlarged prostate and a 35 percent lower risk of moderate to severe urinary symptoms compared to non-users.
Researchers found that childhood polio survivors do not experience significant declines in strength as they age, with only moderate increases in weakness. The study suggests that polio survivors may not age differently than the general population and can expect years of stability without major lifestyle modifications.
The Mayo Clinic team has developed a consensus statement recommending the use of pamidronate over zoledronic acid for starting therapy, and stopping or reducing bisphosphonates after two years for safe management of multiple myeloma. The guidelines aim to minimize adverse reactions while maintaining effective bone disease prevention.
A large international study provides strong evidence that common genetic variants in the alpha-synuclein gene contribute to Parkinson's disease worldwide. Variability in this gene is associated with a 1.5 times greater risk for the disease, highlighting potential therapies to reduce alpha-synuclein protein production.
Researchers found that botulinum toxin injections in early healing phase improve scar appearance and prevent muscle movement wrinkling the wound site. The treatment shows promise for minimizing scarring and optimizing healing outcomes.
Researchers at Mayo Clinic have discovered an association between allergic rhinitis and the development of Parkinson's disease. The study found that people with allergic rhinitis are 2.9 times more likely to develop Parkinson's, highlighting a potential link between inflammation and the disease.
Researchers at the Mayo Clinic have engineered a modified measles virus that specifically targets and kills cancer cells by recognizing unique protein secretions. This breakthrough enhances the safety and effectiveness of oncolytic virotherapy, reducing the risk of unintended infections while improving cancer treatment outcomes.
A new study found that men with multiple sclerosis (MS) are more likely to pass the disease to their children than women. The researchers discovered that fathers with MS have twice as many children who develop MS as mothers with the disease.
Mayo Clinic researchers found robot-assisted, laparoscopic surgery to be effective in repairing vaginal vault prolapse. The procedure resulted in less recovery time, lower risk of bleeding and pain, and higher patient satisfaction compared to traditional open surgery.
Diastolic heart failure is increasingly common, now accounting for over half of heart failure cases. Women, particularly elderly women, are disproportionately affected. Therapies for diastolic heart failure may need to be distinct from those for systolic heart failure.
Researchers at Mayo Clinic have identified a gene mutation causing chaotic electrical activation of the heart muscle and atrial fibrillation. The study found that a specific genetic mutation in the KCNA5 gene leads to susceptibility for atrial fibrillation, providing new insight into its mechanism.
A new Mayo Clinic study finds that executive function, including concentration, decision-making, and higher-order problem solving, deteriorates after memory decline in Alzheimer's disease progression. This decline can cause people to become more impaired in daily activities.
Researchers have defined normal melanocyte numbers in sun-exposed skin, distinguishing sun damage from early melanoma. This finding allows for less tissue removal and trauma to the skin.
A new study using MRI scans has found that the drug donepezil slows brain deterioration in patients with mild cognitive impairment, a condition on the road to Alzheimer's disease. The treatment showed a positive effect on patients who carried the APOE 4 allele, which increases the risk of developing Alzheimer's.
Researchers discovered that women who develop dementia experience a decline in weight up to 10 years before memory loss. The study found that the brains of these women underwent changes before the onset of symptoms, potentially linked to postmenopausal hormonal changes or other factors.
A Mayo Clinic study found that older people and those with chronic illnesses have the highest rates of end-of-life intensive care unit (ICU) use. The study also found that expanding alternative health care settings, such as nursing homes or hospice care, might be a more cost-effective way to fund end-of-life care.
The study found that B7-H4, an immune system blocker, is present in aggressive kidney cancers and vessels, allowing the cancer to grow and spread. This discovery may lead to better treatment options for patients with renal cell carcinoma, a deadly form of kidney cancer.
The Mayo Clinic has pioneered a novel method of jaw reconstruction for oral cancer patients, utilizing distraction osteogenesis after tumor removal surgery. This approach enables patients to receive both radiation therapy and reconstruction concurrently, minimizing scar tissue and improving patient tolerance.
A Mayo Clinic study found that patients with widely fluctuating blood pressure during the first three hours in the emergency room were much less likely to survive more than 90 days after a stroke. The study suggests that managing blood pressure acutely after ischemic stroke is crucial to improve survival rates.
Researchers at Mayo Clinic have identified two cases of 'broken heart syndrome,' a rare condition that mimics a heart attack, resulting from opioid withdrawal and cocaine use. The findings highlight the importance of cautious medication management and patient education to prevent serious complications.
A study found that REM sleep behavior disorder is a precursor to neurodegenerative diseases such as Parkinson's disease and dementia with Lewy bodies. Patients with RBD are at increased risk for developing these conditions, which can lead to serious consequences like brain hemorrhages and death.
A recent study at Mayo Clinic suggests a strong association between REM sleep behavior disorder (RBD) in younger patients and antidepressant use. The study found that 80% of RBD patients under 50 years old used antidepressants, compared to 15% of those over 50.
A new study by Mayo Clinic researchers found that pesticide use increases the risk of Parkinson's disease in men, with a higher likelihood of exposure compared to women. The study matched individuals with Parkinson's disease to those without, assessing exposure via farming occupation or hobbies.
A Mayo Clinic study found that acupuncture significantly improved symptoms of fibromyalgia in patients, including fatigue and anxiety. The study's results lend credence to the effectiveness of non-traditional methods in improving health.
A recent study has shown that trastuzumab reduces recurrence of HER-2 positive breast cancer by 50 percent and does not add complications to radiation treatment. The study was conducted on 1,460 patients who received radiation in the original N9831 group, with no significant difference in side effects.
The study found that the average time to disease progression was approximately eight months for patients taking dexamethasone alone, while those on the Thal/Dex regimen had an average progression time exceeding 17 months. Researchers also reported more frequent side effects with the combination therapy.
Researchers at Mayo Clinic have found a significant association between acid reflux and esophageal cancer, with patients who experience acid reflux having a 30- to 125-fold increased risk of developing esophageal cancer. The study also discovered susceptibility genes in familial Barrett's esophagus and esophageal cancer.
Researchers identified two genes, CAV3 and RyR2, linked to SIDS. The study found molecular and functional evidence in these genes suggesting a possible explanation for the condition. The findings point to the heart as a critical area of investigation for SIDS.
A new study from the Mayo Clinic contradicts previous research suggesting a link between patent foramen ovale (PFO) and stroke risk. The study found that traditional cardiovascular risk factors are more important than PFOs in causing cryptogenic strokes in older adults, while younger patients may have a higher risk associated with PFOs.
A retrospective study found that closing PFOs and atrial septal defects with transcatheter devices is a safe treatment option for children and young adults who have had a stroke. Most patients remained symptom-free months after the procedure.
Mayo Clinic Proceedings editorial highlights need for further research on PFOs and stroke risk. Additional studies will help determine best course of treatment for patients with PFOs.
A study found that patients with rheumatoid arthritis treated with TNF-blocking antibodies are at a higher risk of developing cancer and serious infections. The drugs, which were previously thought to be safe, may interfere with the body's ability to fight off infection and cancer.
The Mayo Clinic study found that brains of people with mild cognitive impairment showed structural changes similar to Alzheimer's disease, but not as severe. The researchers believe this transitional state may indicate a person is on the road to developing Alzheimer's.
A Mayo Clinic study reveals that comas are often grossly misrepresented in movies, with inaccurate depictions of patients' appearances and care. The researchers propose solutions to improve accuracy in film portrayals, including collaborations between screenwriters and neurologists.
The study found no differences in visual acuity, contrast sensitivity, or perception of stray light between the two types of LASIK. Bladeless LASIK showed greater corneal backscatter initially, but patients perceived no difference in vision after three months.
The Mayo Clinic team has discovered that an echocardiography-guided genetic test can be more effective in identifying hypertrophic cardiomyopathy (HCM) mutations, particularly when combined with unique anatomical features of the heart. This approach can help physicians provide more accurate counseling to families and unlock new researc...
A study at Mayo Clinic found that patients treated with shock wave therapy for kidney stones were at higher risk of developing diabetes and hypertension, with risks nearly four times and one-and-a-half times respectively. The researchers believe the association may be due to damage inflicted on the pancreas or scarring in the kidneys.
A study published by Mayo Clinic researchers found that surgical ovary removal elevates the risk of dementia in younger women, possibly due to insufficient estrogen. Women who underwent the surgery at a younger age may be more susceptible to cognitive decline, highlighting the need for ongoing hormone replacement therapy.
A study by Mayo Clinic researchers found that epilepsy surgery is durable and effective, improving quality of life for patients with intractable epilepsy. The procedure removed the focal region of brain disease in 399 consecutive patients, with a 4% risk of complications.
Research identifies three estrogen-related gene variants associated with an increased risk of Parkinson's disease in women. The study found that these genetic variations affect 10-20% of the female population and could be used to predict disease risk using a simple blood test.
The authors outline a vision for a dynamic learning organizational system to ensure quality care at an affordable price. Key elements include professionalism, systems engineering, and information technology to provide universal coverage through a market-based model with government assistance.
Mild cognitive impairment affects 9% of those 70 to 79 and nearly 18% of those 80 to 89. Education years also impact risk: 25% for up to eight years, 14% for nine to 12 years, and 8.5% for greater than 16 years
The Mayo Clinic research identifies a signaling mechanism by which natural killer cells initiate a toxic response against cancers and viruses. The discovery provides crucial information for designing therapies to stop, reverse or protect against cancer.
Researchers found that waves in cancer cells selectively round up activated growth-promoting proteins, which can help terminate signals and prevent cancerous traits. This discovery provides new insights into the role of waves in cancer cell metastasis.
A Mayo Clinic study found that a specific gene profile of HOXB13 and IL17BR is an independent marker of early breast cancer relapse or death in lymph node-negative breast cancer. This discovery has significant clinical implications, suggesting the potential for improved treatment outcomes for high-risk patients.
A study by Mayo Clinic researchers identified 8 genes with significant under-expression and 3 with over-expression, strongly implicating them in prostate cancer development and progression. The findings suggest that these genes may serve as biomarkers for diagnosing and predicting prostate cancer, potentially improving treatment outcomes.
A study analyzing newspaper articles on neurologic diseases reveals 21% stigmatizing language and 20% medical errors or exaggerations, affecting public understanding and health care coverage. Researchers call for more mindful reporting to improve patient attitudes and overall health outcomes.
Researchers found significant and long-lasting heart benefits for bariatric surgery, including improved body weight, lipid levels, blood pressure, and fasting glucose. The study estimated that the surgery could prevent 16 cardiovascular events and 4 overall deaths per 100 patients compared to the control group.
Researchers at Mayo Clinic are testing a revolutionary classroom concept that promotes increased physical activity among children, using advanced technologies such as standing desks and wearable devices. The goal is to prevent childhood obesity by encouraging kids to move more during learning.