A recent study has identified specific genetic mutations that lead to drug resistance and relapse in childhood leukemia. Researchers found 20 relapse-specific mutations, including a mutation in the NT5C2 gene, which may help doctors detect early signs of relapse and switch treatment strategies.
Researchers found that a virulent strain of H. pylori reduced the risk of deaths from stroke by 55% and lung cancer by 45%. The study, which analyzed data from nearly 10,000 individuals, also found no association between H. pylori positivity or cagA-positivity and all-cause mortality.
A study analyzing national survey data found a biomarker for higher risk of heart and kidney disease in children and adolescents associated with BPA exposure. The study suggests that even low levels of BPA increase oxidative stress and inflammation, promoting protein leakage into the urine.
A new study suggests that maraviroc, an HIV treatment drug, could be effective in treating Staphylococcus aureus infections. The discovery was made through a serendipitous finding and further confirmed using mouse models, showing that blocking CCR5 receptor can help control the infection.
Researchers at NYU Langone Medical Center have identified two genes, Hoxa5 and Hoxc5, that establish the neuronal circuits required for breathing. The discovery could advance treatments for spinal cord injuries and neurodegenerative diseases like ALS.
Renowned immunologist Dan R. Littman, MD, PhD, has been elected a member of the Institute of Medicine for his seminal contributions to immune recognition, HIV pathogenesis, and commensal bacteria in immune system development. His work has major impact in both immunology and virology.
Researchers have discovered a specific marker, fibulin-3, that is four to five times higher in the plasma of patients with mesothelioma compared to those exposed to asbestos. The protein demonstrates high sensitivity and specificity for diagnosing mesothelioma, potentially leading to earlier treatment and improved patient outcomes.
A study by NYU School of Medicine found a significant association between higher urinary BPA concentrations and obesity in children and adolescents. Exposure to BPA, a synthetic chemical banned from sippy cups and baby bottles, was linked to increased body mass in white children and adolescents.
A new study reveals that metabolic syndrome is associated with impaired brain function in adolescents, including lower math and spelling scores, decreased attention span, and reduced brain structure. The findings emphasize the importance of addressing childhood obesity to prevent long-term cognitive and brain impairments.
Researchers found that early exposure to antibiotics can alter the gut microbiome, leading to increased fat mass and percent body fat in mice. The study suggests a potential link between antibiotic use in childhood and later development of obesity. Further research is needed to confirm this theory.
A study of over 10,000 children found a correlation between early antibiotic exposure and increased body mass percentile in childhood. Children exposed to antibiotics from birth to 5 months old were more likely to be overweight by 38 months of age.
Researchers at NYU School of Medicine are enrolling patients in a clinical trial testing the use of worm eggs to relieve symptoms of ulcerative colitis. The trial aims to understand how worm eggs may improve symptoms by altering the lining of the intestine and changing the type of bacteria attached.
Experts from NYU Langone Medical Center will present research on non-invasive evaluation of tau targeted immunotherapy, physician intention to screen for dementia, and remission of pre-mild cognitive impairment. These studies aim to improve diagnosis and treatment of Alzheimer's disease.
Researchers at NYU School of Medicine have made a key discovery about the progression of pancreatic cancer, revealing how it escapes immune detection. By targeting a protein called GM-CSF, they found that immune cells can be unleashed to attack and halt tumor development.
Researchers discovered a process that turns off key pathway required for immune system to attack foreign bodies, preventing maternal immune rejection of the developing fetus. Epigenetic modifications in decidua cells silence chemokine genes, inhibiting T cell recruitment and immune response.
Researchers identified a single gene AUF1 controlling inflammation, aging and cancer. The study found that deleting the gene led to accelerated aging.
Scientists at NYU School of Medicine identified a pathway that, if deactivated, may help slow the development of multiple myeloma. By targeting this pathway's cellular transcription process, researchers hope to find an effective treatment for the disease.
A new study suggests that policies to reduce healthcare costs may compromise quality care by depriving patients of needed services. The research found that regions with high rates of inappropriate imaging also had high rates of appropriate imaging, highlighting the need for a more nuanced approach.
A new research survey found that the Bangladeshi community in NYC experiences significant barriers to diabetes care, including low English proficiency and limited awareness. The study also showed a high willingness among respondents to participate in community health programs for prevention and care.
Researchers found an association between H. pylori bacteria and elevated levels of glycosylated hemoglobin (HbA1c), a biomarker for blood glucose levels and diabetes. Obesity was a significant risk factor, suggesting the bacteria may play a role in developing diabetes in adults.
A study published in European Journal of Nutrition found that serum taurine intake was associated with significantly lower coronary heart disease risk among women with high total cholesterol levels. Higher taurine intake was linked to a 60% lower risk of developing or dying from CHD.
A study found that fathers with depressive symptoms are associated with an increased risk of emotional or behavioral problems in children. The research identified factors such as poverty, unemployment, living with a child with special health care needs, and maternal depression as predictors of paternal depressive symptoms.
Researchers have discovered a mechanism by which the immune system tries to halt HIV's spread, focusing on a protein called SAMHD1 that protects cells from viral hijacking. By understanding this mechanism, scientists may find new ways to stop or slow the virus' ability to infect.
The department's second annual analysis of orthopaedic procedures reveals focus areas such as VTE prevention, MRSA control, and reducing readmission rates. NYU Langone Medical Center aims to embed quality and patient safety in every aspect of its work.
A new study found that children who received family intervention during early childhood had significantly lower rates of obesity compared to those in the control group. The intervention, ParentCorps, helped parents develop more effective discipline strategies and increase positive interactions with their children.
Experts from NYU Langone Medical Center will present their latest research on diseases of the muscle, tendon, bone, and joint. The focus includes reverse total shoulder arthroplasty, platelet-rich fibrin matrix for rotator cuff healing, and effects of partial medial meniscectomy on tibiofemoral position and stability.
A recent study published in Stroke journal found that high triglyceride levels are a stronger predictor of stroke risk in postmenopausal women than previously thought. Researchers analyzed data from over 90,000 women and discovered that those with the highest triglyceride levels were nearly twice as likely to suffer an ischemic stroke.
A new study by NYU School of Medicine reveals that positive affirmation, combined with patient education, improves medication adherence rates among hypertensive African-Americans. The study found a 22% increase in adherence rates among participants who received the intervention.
Researchers identify genetic alterations in T-ALL that work together to cause the devastating childhood cancer, providing new potential treatment strategies. The study reveals a dynamic interplay between Notch and PRC2 function, showing how deregulation of PRC2 fuels the development of T-ALL.
A new study by NYU Langone Medical Center researchers identified netrin-1 as a molecule that blocks the normal migration of macrophages out of arteries, causing them to accumulate and promote atherosclerosis. Genetically deleting netrin-1 can minimize atherosclerosis, reduce macrophage levels in plaque, and promote macrophage migration.
Researchers discovered how statins promote the breakdown of plaque by activating a cell surface receptor, forcing macrophages out of plaque. The study supports clinical findings that high-dose statins reduce cholesterol levels and plaque amount in arteries.
A study led by Dr. Charles Marmar found that police recruits with higher cortisol awakening responses were more likely to experience acute stress symptoms in response to trauma years later. The study suggests that measuring cortisol levels could be a potential indicator for identifying those at high risk for PTSD.
Experts from NYU Langone's Department of Radiology will present on various topics, including genitourinary evaluations and breast MRI outcomes. The department is a leader in advanced diagnostic imaging with over 100 board-certified radiologists.
Researchers have discovered the FBXO11 gene as a novel tumor suppressor in B-cells, which regulates BCL6 protein levels. Deletions or mutations of FBXO11 contribute to DLBCL's development, with reconstitution of its expression inhibiting proliferation and inducing cell death.
Researchers found that high levels of dendritic cells in the pancreas can alleviate cellular stress caused by severe inflammation, while low levels are associated with exacerbated pancreas injury. Dendritic cells play a critical protective role in pancreatic organ survival.
A new animal study led by NYU Langone researchers shows that the sense of smell can be improved through training. The study found that rats trained to discriminate between similar odors could develop distinct brain activity patterns, while those not trained lost their ability to distinguish.
Researchers at NYU Langone Medical Center have discovered a protein called TAT-5 that inhibits the budding of extracellular vesicles from cells, affecting tumor spread, blood clotting, and inflammation. The study reveals new potential strategies to manipulate diseases like cancer.
A recent study by NYU School of Medicine reveals that hydrogen sulfide (H2S) plays a crucial role in protecting bacteria from various antibiotics. By targeting bacterial gas defenses, researchers aim to develop new strategies for increasing antibiotic efficacy and combating antibiotic resistance.
Experts from the Rusk Institute of Rehabilitation Medicine will discuss advances in personalized medicine for neuromuscular care, as well as treatment strategies for traumatic brain injuries. They will also explore the integration of handheld technologies into practice management.
NYU Langone experts will present research on brain networks, cognition, and memory at the annual meeting. The institution's Neuroscience Institute connects scientists with clinicians to tackle complex healthcare issues.
Sudden unexpected death in epilepsy (SUDEP) affects 2.7 million Americans, with a high risk associated with chronic and severe cases. Increased awareness, improved prevention, and better treatments can help reduce SUDEP rates through devices that detect seizures and understanding its mechanisms.
Dr. Abramson is recognized for his research and contributions to the field of rheumatology, with over 200 publications in top-tier journals. He has also held key positions in academic institutions and regulatory agencies.
Experts from NYU Langone Medical Center presented new research findings on osteoarthritis, lupus, and rheumatoid arthritis at the American College of Rheumatology 2011 Annual Scientific Meeting. A study found that increased prescription of narcotic analgesics for OA in the elderly is associated with increased falls and fractures.
Researchers at NYU Langone Health have identified the CK1 protein as a key player in cancer cell development. Inhibiting this enzyme may provide a new approach to treating cancer cells, particularly those with malfunctioning mTOR signaling pathways.
Researchers at NYU Langone Health have identified microRNA-33a/b as a novel therapeutic target to suppress triglyceride levels and increase high-density lipoprotein cholesterol (HDL-C). The study shows that inhibition of miR-33a/b markedly suppresses triglycerides and causes a sustained increase in HDL-C.
Researchers at NYU Langone Medical Center explore how gut bacteria influence cancer risk, suggesting early exposures to H. pylori may protect against gastric cancers later in life. The study also highlights the estrobolome, a framework for understanding estrogen's impact on cancer development.
Researchers at NYU Langone Health identified a hidden cause of heart attacks in women without significant coronary artery disease. Plaque disruption, a rupture or ulceration of cholesterol plaque in a coronary artery, was found to be the mechanism behind myocardial infarction in some women.
Scientists found an antidepressant and antipsychotic that effectively combat prion infections in mice, potentially treating human prion diseases like Creutzfeldt-Jakob disease. The compounds also reduced disease symptoms and delayed symptom onset.
Researchers deciphered the sparse genome of segmented filamentous bacteria (SFB), a key player in regulating the immune system of mice. The study suggests SFB is genetically distinct from other bacterial genomes, with a unique role in promoting immune responses that protect against infection but also spur inflammation.
Researchers discovered dendritic cells play a protective role in the liver against acetaminophen-induced acute liver failure. High levels of dendritic cells are associated with protection, while low levels exacerbate liver damage and death.