Researchers at NYU Langone Health found that infection with a common virus helped mice repair damaged intestinal tissue and restore their immune defenses. The study suggests that the virome, or natural presence of viruses in the gut, plays a crucial role in maintaining health and fighting infections.
A study led by NYU Langone Medical Center found that a mother's soothing presence can alter gene activity in an infant's brain, reducing pain and promoting emotional development. This research offers new insights into the short-term effects of maternal caregiving on a developing brain.
Researchers have developed a new diagnostic technique using songbird courtship calls to safely map the human brain during complex neurosurgery. The technique, called focal intraoperative cooling, involves cooling specific regions of the brain while patients undergo surgery, reducing surgical risk for epilepsy and brain tumor patients.
Researchers at NYU Langone Medical Center found that calorie-restricted diets slowed the normal rise and fall of genes linked to aging and memory formation in the brain. The study used female mice fed food pellets with 30% fewer calories than controls, and tissue analyses showed a significant impact on gene expression.
A novel tool called 'telomerator' enables the creation of linear yeast chromosomes with precise telomere endings, improving gene study and engineering. This advancement allows researchers to test how genes interact with their chromosomes, promoting more realistic synthetic biology.
Researchers at NYU Langone Medical Center found that sleep apnea disrupts REM stage sleep, impairing spatial memory in humans. Sleep apnea can lead to longer completion times in a 3D maze, even when other sleep stages are intact.
Researchers at NYU Langone Health have made breakthroughs in treating T-cell acute lymphoblastic leukemia by blocking the action of an enzyme called JMJD3. The treatment, GSKJ4, has shown promising results in mice and human lab cells, with cancer cells dying when treated with the experimental drug.
Researchers at NYU Langone Medical Center are working on a five-year contract to discover fundamental immunology, microbial genetics, and protein structure of Staphylococcus aureus. The goal is to identify Sa antigens that are crucial for effective immune defenses.
Researchers at NYU Langone Medical Center have identified a protein known as Pcp4 as a regulator of the heart's rhythm in mouse models. Disruption of the Pcp4 gene leads to ventricular arrhythmias and increased mortality. The study suggests that targeting Pcp4 could lead to new treatments for arrhythmias.
A new study found that overuse of cardiac stress testing with imaging in the US leads to unnecessary radiation exposure, healthcare costs, and potential cancer risk. The researchers estimated that at least 34.6% of tests were probably inappropriate, resulting in $501 million annual costs and 491 future cases of cancer.
Researchers analyzed cultural and historical forces to estimate historic changes in UV exposure contributing to the rise in melanoma cases. Changes in fashion and clothing design, as well as increased leisure time and sun exposure, are identified as key factors.
Researchers found that the protein BRD4 plays a crucial role in regulating stem cell identity, holding promise for regenerating tissues and organs. The study suggests that inhibiting BRD4 could be used to reprogram stem cells into specific cell types, such as neurons.
Researchers at NYU Langone Health have discovered a highly efficient method for generating pluripotent stem cells, increasing yields by over 20-fold compared to standard protocols. The new technique uses vitamin C and two other compounds to modulate enzymes involved in cell reprogramming.
A new study by NYU Langone Medical Center identifies a specific neurobiological basis for key symptoms of post-traumatic stress disorder (PTSD), including sadness, emotional detachment, and listlessness. The research uses brain imaging to link an opioid receptor in the brain to these symptoms, suggesting a potential target for personal...
Researchers successfully harness a mouse's immune system to remove toxic proteins in the brain associated with Alzheimer's disease. The treatment approach, which stimulates the natural immune system, showed promise in reducing amyloid beta plaques and tau tangles.
Researchers at NYU Langone Medical Center found that technology-assisted weight loss interventions, including web-based applications and software, can be an effective option for primary care patients. These interventions resulted in average weight losses of up to 5.4 kilograms (12 pounds) over a 36-month period.
A new study suggests that early antibiotic exposure disrupts the gut microbiome, permanently altering metabolism in mice. Researchers found that mice exposed to low-dose penicillin during pregnancy or nursing were more susceptible to obesity and metabolic abnormalities than those exposed later in life.
A study published in Cell reveals that the thalamic reticular nucleus acts as a 'switchboard' directing sensory signals during wakefulness and internal information during sleep. This 'switchboard' is crucial in attention and sleep, with faulty cells potentially disrupting filtering of information in psychiatric disorders.
Researchers at NYU Langone Medical Center identified a possible new drug target, LUNAR1, for treating childhood blood cancer. Blocking LUNAR1's action stalled leukemia progression and may offer an alternative to standard chemotherapy.
Researchers from NYU Langone will present new findings on tau immunotherapy and its potential for treating Alzheimer's disease. The presentations focus on the role of mitochondria and death receptors in amyloid toxicity, which may lead to improved treatment options for patients.
Researchers found that maternal presence and social interactions directly mold infant brain activity and growth. The study showed that the mother's presence regulated and controlled electrical signaling in the infant pup's brain, leading to healthy brain development.
According to a recent study by NYU researchers, nearly 1 in 5 high school seniors use hookah. Hookah use is more common among students from higher socioeconomic backgrounds and those living in cities. Researchers caution that the increasing popularity of hookah pens may normalize their use, leading to potential health consequences.
Brain cancer specialists argue that current science is guiding compromising care, emphasizing the need for individualized treatment approaches. They identify five misconceptions that lead to poorer care, including assuming all tumor cell types act similarly and neglecting important biological differences.
Researchers found that even uninfected cells can trigger immune defenses against TB by transferring immune-stimulating proteins from infected dendritic cells. This discovery could lead to more effective vaccines, including the BCG vaccine for TB, which works on a similar principle.
A NYU Langone expert suggests reforms to improve the VA health system's administration, staffing, and management. Key proposals include changing the culture, creating new scheduling systems, and hiring more primary care physicians to meet the growing demand.
Researchers found that sleep after learning encourages the growth of dendritic spines in mice, which helps consolidate and strengthen new memories. The activity of brain cells during deep sleep is critical for this process, suggesting a physical mechanism for how sleep enhances memory formation.
Scientists have identified a compound, 2-PMAP, that reduces amyloid proteins in the brain by over half and may be safe enough to be taken daily. The researchers hope it could be used to ward off Alzheimer's disease.
Researchers at NYU Langone Health discovered a robust backup DNA repair mechanism in yeast cells that prevents common genetic mutations. This finding suggests a similar system may exist in humans, providing potential new targets for controlling some cancers and treating Aicardi-Goutieres syndrome.
A rare type of melanoma that affects darker skins is almost twice as likely to recur as other similar types of skin cancer. The study found that acral lentiginous melanoma has a high recurrence rate, especially in small tumors.
Researchers at NYU Langone Health found a link between autism and two biological pathways in mice with Mohawk-like hairstyles. The study suggests that reversing these effects could lead to potential treatments for the disease.
Researchers found that 69% of healthy Americans are infected with one or more of 109 HPV strains, most of which appear harmless. The study highlights the complexities of the HPV viral biome and the need for broader diagnostic tests to accurately assess infection status.
The procedure has been found to be highly effective in restoring people to fully functioning lives after physically disfiguring facial injuries, with most patients experiencing significant psychological improvements. However, the treatment still poses lifelong risks and complications, including rejection and infection.
A large-scale survey of 3.5 million Americans found that married people have a significantly lower risk of heart disease than singles, divorced, or widowed individuals. The study also revealed age-related differences in cardiovascular disease risk among married couples.
Researchers at NYU Langone Health have synthesized a fully functioning chromosome in yeast using computer-aided design, overcoming the biggest hurdle in synthetic biology. The seven-year effort built a chromosome with over 270,000 base pairs, enabling new capabilities and traits in yeast cells.
Researchers at NYU Langone Medical Center found that blocking the action of a key signaling molecule, Netrin-1, stalls chronic inflammation and insulin resistance tied to obesity. This could lead to further advances against diseases such as type II diabetes and atherosclerosis.
Researchers at NYU Langone Medical Center discovered that blocking Netrin-1 stalls chronic inflammation and insulin resistance, a link between obesity and type II diabetes. The study found that Netrin-1 signaling promotes macrophage buildup in fat tissue, leading to inflammation and insulin resistance.
Researchers at NYU Langone Health have found a biological weakness in mutant K-Ras, the most commonly mutated gene involved in human cancers. By blocking the activity of related genes H-Ras and N-Ras, chemotherapy drug irinotecan can stall tumor growth.
Researchers at NYU Langone Health discover how RNA polymerase patrols the genome for DNA damage and recruits partners to repair it, leading to fewer mutations and less disease. The study's findings have major implications for our understanding of DNA repair and its role in cancer and aging.
A large epidemiological study discovered a clear association between gut bacteria and colorectal cancer. Colorectal cancer patients had fewer beneficial bacteria and more harmful bacteria than healthy individuals.
Despite mandatory calorie postings, customers' purchasing habits and calorie intake remained unchanged. The study, conducted in Philadelphia and Baltimore, found that only a small percentage of customers noticed the labels, leading to minimal behavioral change.
Researchers found that Prevotella copri was more abundant in patients with newly diagnosed rheumatoid arthritis than healthy individuals or those with chronic, treated rheumatoid arthritis. The study suggests a possible link between the growth of this intestinal bacteria and the onset of autoimmune attacks on the joints.
Researchers from NYU Langone presented new findings on a drug called hydroxychloroquine, which shows promise in preventing recurrent heart disease in at-risk pregnancies. The study identified multiple genetic risk variants for congenital heart block and may lead to new therapies for autoimmune and rheumatic conditions.
Researchers at NYU Langone Medical Center discovered a mechanism by which Staphylococcus aureus bacteria attack and kill off immune cells. The toxin selectively binds to surface receptors on different types of white blood cells, including neutrophils and T-cells.
Researchers at NYU Langone are leading a $6.25 million, five-year research initiative to find targeted treatments for children with acute lymphoblastic leukemia (ALL), the most common form of childhood cancer. The project aims to improve the cure rate and reduce mortality rates among ALL patients.
A study led by NYU Langone researchers found that body fat and mortality due to cardiovascular disease differ between south and east Asians. A high BMI above 24.9 is a strong risk factor for death among East Asians, but not among South Asians.
A groundbreaking study led by NYU Langone Medical Center has identified nine specific genes with four completely new mutations associated with two severe forms of epilepsy: infantile spasms and Lennox-Gastaut syndrome. These genetic risk factors may lead to personalized therapy and drug development.
A mathematical model helps clinicians prioritize recommended preventive care methods, leading to enhanced care and potential lifesaving outcomes. The model, developed by NYU Langone researchers, takes into account individual patient needs and provides personalized recommendations.
NYU Langone researchers have identified the type of inhibitory interneurons responsible for oxytocin's effects on brain function. The study found that oxytocin increases the reliability of stimulated impulses, improving brain function and potentially relevant to autism-spectrum disorder.
A Swedish data-sharing campaign led to a significant decrease in unnecessary medical tests for low-risk prostate cancer patients. The study suggests that curtailing unneeded medical tests is achievable and offers insights into the importance of implementing guidelines and providing feedback to practitioners.
Experts from NYU Langone Medical Center will present new research on advanced treatments for neurodegenerative diseases, including Alzheimer's disease. The Comprehensive Center on Brain Aging is devoted to research and clinical advances toward the treatment and cure of all neurodegenerative diseases.