Medical ethicists propose a solution to the US organ shortage crisis by introducing an 'uncontrolled donation after circulatory determination of death' (UDCDD) approach. This method considers deceased individuals for donation even outside hospitals, allowing families to decide later if they want to preserve organs for potential donation.
A new study found that nearly all parents of overweight boys and approximately 88% of parents of overweight girls perceive their children as 'about the right weight'. The researchers also found that African-American families are more likely to misperceive their child's weight, while family income increases lead to correct perceptions.
Researchers at NYU Langone Medical Center identified a crucial role for calcium signaling in controlling inflammation during chronic lung infection caused by Mycobacterium tuberculosis. Calcium channels play a key role in shutting down the immune response and preventing injurious inflammation.
Researchers at NYU Langone discovered that mitochondria are essential for stem cell development, directly controlling the growth and maintenance of inner membranes inside mitochondria. The study found that blocking ATP synthase stalled egg cell development from stem cells in fruit flies.
A new study found that nearly 40% of multiple sclerosis patients who stopped taking their medication experienced some level of disease activity. Patients who stopped taking their medication were more likely to experience relapses and disability progression than those who continued treatment.
The new guidelines emphasize the importance of discussing treatment options with patients after a first seizure, weighing individual risks and benefits. Immediate treatment with an epilepsy drug may reduce recurrent seizures within two years, but its effectiveness decreases after three years.
A study of 1,964 patients found extending natalizumab dosing up to 8 weeks is well-tolerated and effective in treating MS disease activity. No cases of progressive multifocal leukoencephalopathy were reported in the extended dosing group.
Researchers discovered an unprecedentedly diverse collection of bodily bacteria in isolated Yanomami Indians, with a 40% lower diversity than those in industrialized countries. The study suggests a link between modern antibiotics and reduced microbiome diversity, potentially driving diseases like obesity and diabetes.
Researchers have discovered how oxytocin acts on individual brain cells to prompt specific social behaviors. Adding oxytocin to adult mice' brains allowed them to learn and perform social tasks, suggesting potential treatments for social anxiety and post-traumatic stress disorder.
In a deadly, rapidly spreading infectious disease like Ebola, traditional randomized clinical trials may be inadequate. Alternative trial designs can provide useful information and are morally justifiable, says a new article in the American Journal of Bioethics.
A pilot study published in Addiction journal found that extended-release naltrexone significantly reduced opioid relapse rates among mostly heroin-dependent men released from New York City jails. After one month, 88% of participants in the control group relapsed, compared to 38% in the treatment group.
The scientific community is facing a 'pollution problem' due to plagiarism, fraud, and predatory publishing, threatening the trustworthiness and reliability of research. Dr. Arthur Caplan proposes a national meeting to address this issue and promote sustainable publishing practices.
A molecular pathway permits stem cells to grow rapidly and aggressively in pediatric bone cancers, according to researchers at NYU Langone Health. The transcription factor Sox2 releases the floodgates in the Hippo pathway, allowing for the growth of highly aggressive tumor-forming stem cells.
Researchers tracked neuronal activity in dendritic nerve branches as mice learned motor tasks, finding that calcium ion spikes triggered changes in connection strengths. The study identified a unique cell type controlling lightning bolt patterns, which stored new information without disrupting existing memories.
A new study from NYU Langone Health has identified the most common causes of hospital readmissions following total hip and knee arthoplasty procedures. The study found that surgical complications accounted for 54% of readmissions, with an average cost of $36,038 for total hip replacements and $61,049 for total knee replacements.
Researchers at NYU Langone found that adolescent patients who undergo high-volume scoliosis surgery have significantly lower reoperation rates compared to those with low-volume surgeons. The study suggests that experienced spine surgeons can reduce complications and need for revision surgeries.
A study published by NYU Langone researchers found that patients with diabetes who undergo ankle fracture surgery have significantly longer lengths of stay and total hospital charges compared to non-diabetics. Patients with complicated disease also experience worse trends, with increased costs and prolonged hospital stays.
As the US population ages, chronic subdural hemorrhage (SDH) is expected to become the most common adult brain condition requiring neurosurgical intervention. By 2030, hospitals and neurosurgeons may be under-manned to handle the projected increase in patients with SDH.
A new survey from NYU Langone Medical Center found that most physicians believe diet is as important as statin therapy in preventing heart disease, and would welcome additional training in nutrition. The study suggests that improving physician knowledge on diet could lead to better patient outcomes.
A study of over 18,000 patients found that newer drug-coated stents have similar long-term rates of death as traditional bypass surgery. However, the stent group had slightly more heart attacks in the long term.
A new computational tool identifies 800 ways people are at increased risk for post-traumatic stress disorder (PTSD), allowing for personalized prediction guides. The algorithm, developed by NYU Langone Medical Center researchers, can predict PTSD risk less than two weeks after a traumatic event.
Researchers analyzed medical test records for over 300,000 people and found a significant link between fine-particulate-matter pollution and stenosis in internal carotid arteries. This study suggests that lowering pollution levels may reduce the incidence of carotid artery stenosis and stroke.
The new quality measures aim to improve detection and treatment of childhood obstructive sleep apnea (OSA) by tracking the quality of services provided by clinicians. The measures, endorsed by the American Association of Sleep Medicine, focus on five desirable processes for pediatric patients with suspected OSA.
A new study from NYU Langone Medical Center found that over 40% of low-risk prostate and breast cancer patients in certain US regions received inappropriate tests. The research suggests that regional culture and infrastructure play a significant role in the use of imaging tests, with some areas exhibiting more appropriate use than others.
Researchers found that brain cells coding for direction remained electrically active during deep sleep as they were during wake time, with visual and vestibular cues guiding them. This discovery could help develop navigational treatments for Alzheimer's and other neurological disorders.
Researchers are advancing blood biomarker capabilities using the Simoa technology, which offers unprecedented improvement in sensitivity proteins for detecting traumatic brain injury. The technology allows for more effective measurement of low concentrations of proteins such as tau, enabling more accurate diagnosis and treatment.
Researchers at NYU Langone Medical Center discovered that the specialized DNA-binding protein CTCF is essential for precise gene expression in developing embryos. The findings shed light on how Hox genes maintain cellular positioning and position-specific gene regulation.
A new study by NYU Langone Medical Center researchers found that locating full-service supermarkets in food deserts has no appreciable impact on household food availability or children's dietary intake. The introduction of a government-subsidized supermarket did not result in significant changes in dietary habits, despite the expectati...
The NYU Langone-Technion partnership aims to accelerate breakthroughs in cancer research through joint efforts. Funded by a $9 million gift, the partnership will support six cancer-focused research projects and establish a state-of-the-art research facility in Israel.
Two tiny bits of non-coding genetic material, miR-382 and miR-516b, have been found critical to stalling melanoma's spread in early-stage tumors. These microRNAs may help identify patients most likely to spread and benefit from more aggressive therapy.
Researchers at NYU Langone Health have discovered a new pathway to slow down tumor growth in cancers with BRCA1 and BRCA2 genetic mutations. By inhibiting the action of polymerase theta enzyme, cancer cell growth can be cut by more than half.
Researchers at NYU Langone Medical Center developed a novel eye-tracking device to diagnose concussion severity, tracking pupils for over 200 seconds while watching a music video. The study found that trauma patients with normal CT scans were slightly worse at 1-2 weeks after injury and recovered about one month later.
Researchers discovered that trauma-related cues from infancy can lower depressive-like behavior in adults, contrary to previous expectations. The study found that these cues altered the brain's serotonin levels, leading to mood uplift and alleviating depression in grown rats.
Researchers at NYU Langone Medical Center stress the importance of blink assessment in facial transplant procedures, as well as during and after surgery. Careful evaluation can help preserve vision and prevent complications such as corneal exposure and eyelid retraction.
Scientists at NYU Langone Health successfully vaccinated deer against chronic wasting disease (CWD), a fatal brain disorder caused by prions. The vaccine holds promise against similar brain infections in humans and may prevent the spread of CWD to U.S. livestock.
Researchers at NYU Langone Medical Center discovered that the gene AUTS2, linked to autism spectrum disorders, stimulates other genes in early brain development. The study suggests that AUTS2 may play a key role in controlling a transcriptional program during early brain development.
Researchers at NYU Langone Medical Center developed new technology that tracks eye movements to assess brain injuries, offering a potential biological marker for brain function and recovery. The study found abnormal eye movement ratios in patients with nerve damage or swelling in the brain, which were restored after surgery.
Researchers at NYU Langone Medical Center developed a genetically engineered pig model to study inherited arrhythmic syndrome, shedding light on the mechanisms of lethal arrhythmias. The model may lead to the development of better treatments for life-threatening arrhythmias and sudden cardiac death.
A new study shows that hospitals adopting robotic surgery between 2001-2004 performed partial nephrectomies more frequently, preserving organs for kidney cancer patients. This increase in partial nephrectomy rates is attributed to greater institutional experience with robotic surgery.
Researchers at NYU Langone Health found that infection with a common virus helped mice repair damaged intestinal tissue and restore their immune defenses. The study suggests that the virome, or natural presence of viruses in the gut, plays a crucial role in maintaining health and fighting infections.
A study led by NYU Langone Medical Center found that a mother's soothing presence can alter gene activity in an infant's brain, reducing pain and promoting emotional development. This research offers new insights into the short-term effects of maternal caregiving on a developing brain.
Researchers have developed a new diagnostic technique using songbird courtship calls to safely map the human brain during complex neurosurgery. The technique, called focal intraoperative cooling, involves cooling specific regions of the brain while patients undergo surgery, reducing surgical risk for epilepsy and brain tumor patients.
Researchers at NYU Langone Medical Center found that calorie-restricted diets slowed the normal rise and fall of genes linked to aging and memory formation in the brain. The study used female mice fed food pellets with 30% fewer calories than controls, and tissue analyses showed a significant impact on gene expression.
A novel tool called 'telomerator' enables the creation of linear yeast chromosomes with precise telomere endings, improving gene study and engineering. This advancement allows researchers to test how genes interact with their chromosomes, promoting more realistic synthetic biology.
Researchers at NYU Langone Medical Center found that sleep apnea disrupts REM stage sleep, impairing spatial memory in humans. Sleep apnea can lead to longer completion times in a 3D maze, even when other sleep stages are intact.
Researchers at NYU Langone Health have made breakthroughs in treating T-cell acute lymphoblastic leukemia by blocking the action of an enzyme called JMJD3. The treatment, GSKJ4, has shown promising results in mice and human lab cells, with cancer cells dying when treated with the experimental drug.
Researchers at NYU Langone Medical Center are working on a five-year contract to discover fundamental immunology, microbial genetics, and protein structure of Staphylococcus aureus. The goal is to identify Sa antigens that are crucial for effective immune defenses.
Researchers at NYU Langone Medical Center have identified a protein known as Pcp4 as a regulator of the heart's rhythm in mouse models. Disruption of the Pcp4 gene leads to ventricular arrhythmias and increased mortality. The study suggests that targeting Pcp4 could lead to new treatments for arrhythmias.
A new study found that overuse of cardiac stress testing with imaging in the US leads to unnecessary radiation exposure, healthcare costs, and potential cancer risk. The researchers estimated that at least 34.6% of tests were probably inappropriate, resulting in $501 million annual costs and 491 future cases of cancer.
Researchers analyzed cultural and historical forces to estimate historic changes in UV exposure contributing to the rise in melanoma cases. Changes in fashion and clothing design, as well as increased leisure time and sun exposure, are identified as key factors.