Researchers found that cells without genetic predisposition have a lower mutation rate in PIG-A gene, ranging from 1 in 3 million to 1 in 300,000. A new test for the mutation rate could identify individuals at high cancer risk and help prevent or treat it.
Researchers identify neuregulin gene as key factor in myelin production, enabling faster neural transmission. The discovery opens possibilities for repairing damaged spinal cords and brain tracts.
Researchers found that sensory deprivation prevented substantial synapse loss in growing mice, contradicting the widely-held notion that brain neurons naturally lose connections as they form new ones. The study's findings suggest a potential link between childhood experiences and long-lasting impacts on brain function.
Chronic wounds like bedsores affect millions in US, causing widespread infections and limb amputations. Researchers found skin cells get stuck in healing process due to overabundance of c-myc, a molecule that suppresses cell migration and causes thickened layers around the wound.
A new computer program, HipMask, uses brain scans to predict future Alzheimer's disease, offering a possible tool for early screening. The technique measures metabolic activity in the hippocampus, which diminishes in size as Alzheimer's progresses.
Researchers at NYU Langone Health have developed the first mucosal prion vaccine that protects mice from developing prion disease by up to 500 days. The vaccine uses proteins found on disease-causing organisms and has shown promising results in preventing the progression of prion diseases.
Scientists discover NKT cells primarily patrol liver blood vessels, showcasing agility and rapid movement. The study reveals surprises about NKT cell behavior, including their ability to survive without the CXCR6 gene.
Researchers expand the ABCD rule to recognize changing characteristics of early melanomas, especially nodular melanomas. The new guideline aims to improve detection and diagnosis of this aggressive form of skin cancer.
A small-scale study of GVG, a drug approved for epilepsy in Mexico, found that it can help patients with methamphetamine and cocaine addiction stay abstinent for up to four weeks without visual side effects. The results are promising, but more large-scale studies are needed to confirm the treatment's efficacy.
A new animal study suggests that antioxidant vitamins may increase the secretion of VLDL in liver cells, leading to higher levels of LDL cholesterol. The study found that vitamins hampered a process in the liver that prevents the production of harmful lipoproteins.
A study published in the American Journal of Psychiatry found that enhanced counseling, including individual and family therapy, reduced symptoms of depression among caregivers of loved ones with Alzheimer's disease. After one year, 29.8% of caregivers in the enhanced group showed significant improvement.
A new study found that children who stayed in the ICU for more than 48 hours after cardiac surgery were at a higher risk of developing post-traumatic stress disorder (PTSD). Five out of 43 children met diagnostic criteria for PTSD, with symptoms including disorganized behavior, nightmares, and concentration problems.
A recent study has revealed that bacteria do indeed inhabit the esophagus, with researchers discovering over 95 species of microbes in healthy tissue. The findings have significant implications for treating diseases such as gastroesophageal reflux disease (GERD) and may one day lead to new treatments using antibiotics.
A team of researchers has identified a protein called APC that regulates cell growth and limits the development of cancer. By controlling the levels of another protein Skp2, APC helps prevent cancer cells from growing uncontrollably.
A new clinical trial called TREE-2 is evaluating the safety and efficacy of three regimens of ELoxatin as a first-line treatment for patients with metastatic colorectal cancer. The study combines an effective anti-angiogenesis antibody with chemotherapy to improve treatment outcomes.
A study published in Nature Biotechnology found that the Sindbis virus is effective at killing tumors in mice, with varying time and injection schedules required. The virus targets tumor cells by binding to a specific receptor, making it a potential tracking device for cancer.
In a groundbreaking study, researchers at NYU School of Medicine found that young nerve cells can rewire their developmental timeline, defying long-held assumptions about brain development. This discovery opens up new possibilities for generating neural tissue for replacement therapies.
A new analysis has found that long-term exposure to air pollution is associated with a 31% increase in the risk of dying from ischemic heart disease. The risk is comparable to that of being a former smoker, according to researchers at NYU Langone Health.
Researchers at NYU School of Medicine developed a new technique to measure brain volume, identifying healthy individuals who would later develop memory impairment. The study found that the medial-temporal lobe shrank considerably more in people with Alzheimer's disease compared to those without it.
Researchers identified a bull's eye-shaped structure between white blood cells that enhances sensitivity to antigens but cuts off signaling beyond a threshold, preventing T-cell death. This adaptive control device enables the immune system to respond to signs of infection over a wide range of magnitudes.
A study led by NYU Langone Health found that epilepsy drug GVG helped hard-core cocaine addicts stay clean for over 60 days. Forty percent of participants achieved sobriety without leaving their environment, gaining weight and living with their families.
NYU researchers identify a gene, luxS, necessary for robust growth of the bacterium in test tubes. This discovery opens up new avenues for developing antagonists or inhibitors to control anthrax, a highly lethal bacterial infection.
A recent survey found that nearly half of primary care physicians feel uncertain in diagnosing adult ADHD, highlighting the need for better training and symptom assessment tools. The survey also revealed that only 34% of physicians report being knowledgeable about adult ADHD, compared to 92% for depression.
Researchers at NYU Langone Health have found that the new antibiotic linezolid is effective against multidrug-resistant tuberculosis (TB), a disease that affects millions worldwide. The drug was administered to five patients who had run out of other treatment options, and all showed significant improvement.
A new study by NYU Langone Health's cardiac surgeons found that off-pump coronary artery bypass grafting (OPCAB) reduces hospital mortality, stroke risk, and complication rates in high-risk patients with severe aortic atherosclerosis. OPCAB results in lower mortality rates (6.5% vs 11.4%) and shorter hospital stays compared to conventi...
Memantine, a new drug, has been found to slow the mental and physical deterioration of patients with moderate to severe Alzheimer's disease. The study, led by Dr. Barry Reisberg, showed that patients taking memantine experienced significantly less decline in cognition and daily life activities compared to those receiving a placebo.
Researchers have identified bone marrow stem cells with the ability to produce functional insulin-producing cells, offering a new potential avenue for treating diabetes. The study used a molecular biology technique called CRE-loxP to isolate and study these cells, which were found to exhibit characteristics of pancreatic beta cells.
A study published in the Proceedings of the National Academy of Sciences found an association between impaired glucose regulation and reduced hippocampal volume, leading to poorer memory performance. This suggests that improving glucose tolerance may have significant treatment implications for age-related cognitive decline.
Scientists have identified specific genes on chromosome 21 that contribute to Down syndrome, a condition affecting one in 800 live births. The discovery provides a roadmap for understanding the genetic causes of the disorder and potentially developing new therapies.
A study published in the Journal of the National Cancer Institute found that higher levels of the molecule HDM2 are associated with a better prognosis in patients with melanoma. Patients with high levels of HDM2 lived significantly longer after treatment than those with low levels, even ten years after diagnosis.
A new study published in PNAS found that the stomach-dwelling H. pylori bacterium has been present in humans for at least 11,000 years, with genetic variations consistent with Asian migration to the New World. The research provides strong evidence supporting the theory that migrating Asians introduced the bacteria to South America.
Researchers have found that a specific carcinogen in cigarette smoke causes mutations in the K-RAS gene, leading to lung cancer. The study uses a mapping technique pioneered by Dr. Tang to pinpoint the exact site of damage, providing concrete proof that smoking is a cause of lung cancer.
A new study confirms that children with ADHD have smaller brains than those without the disorder, but found that stimulant medications do not affect brain size. The research, led by Dr. F. Xavier Castellanos, also showed that brain development in children with ADHD is normal and healthy.
Researchers have found genes in Anopheles mosquitoes that enable them to resist infection by the deadly malaria parasite. The discovery could lead to new strategies to prevent malaria transmission by spreading the parasite-blocking genes among mosquito populations.
The development of a 3D animated heart took one and a half years to complete, using multiple ovine data sets from a Stanford University study. Medical animation software integrated into robotic systems will create a new modality in visualization for cardiac surgery.
Researchers discover that Staph's toxic shock toxin inhibits production of other toxic proteins, leading to reduced disease severity. This breakthrough understanding sheds light on the complex ways Staph causes life-threatening infections.
A vaccine has been shown to delay symptoms of prion brain disease in mice by inducing an immune response and producing antibodies. This breakthrough could potentially lead to a therapeutic response and prevent the disease in animals at risk.
A new study suggests that taking aspirin three or more times a week for six months may reduce the risk of developing non-small cell lung cancer in women. However, larger studies are needed to confirm these findings and determine the optimal dose due to potential side effects like gastrointestinal bleeding.
A nationwide study found long-term exposure to air pollution with high concentrations of tiny particles increases the risk of dying from lung cancer and heart disease. Fine particulate matter levels comparable to second-hand smoke pose significant health risks in polluted cities.
A new fund has been established to provide lifesaving surgery for European children, with generous contributions from private citizens in the US and Germany. The Children's Hope Fund, supported by NYU Medical Center, aims to save as many lives as possible through surgical interventions.
A new study using brain PET scans identifies metabolic changes in older adults that may indicate an increased risk of Alzheimer's disease. Researchers hope to develop a diagnostic tool to identify individuals at risk for the disease, allowing them to take preventive measures.
New York University researchers found an antibody that destroys platelets, which are essential for the blood to clot. The discovery may lead to new treatments for thrombocytopenia, a condition associated with HIV infection and other vascular diseases.
Researchers found that bisexual and homosexual Caucasian men with one copy of the delta-32 mutation have a 70% reduced risk of HIV infection compared to those without the mutation. The study, published in the Journal of Acquired Immune Deficiency Syndromes, provides insight into resistance to HIV infection among high-risk populations.
Researchers at NYU Langone Health successfully immunized mice against Alzheimer's disease using a new vaccine that reduces amyloid plaque and soluble beta levels. The vaccine, modeled on a modified peptide, appears to be non-toxic and shows great promise for the treatment of Alzheimer's disease.
Researchers have isolated a new version of a herpesvirus that kills cancer cells but spares normal tissue, dramatically reducing prostate cancer tumors in mice. The new virus contains an extra genetic mutation that enables more robust reproduction and prevents the cell from mounting a response to stop viral replication.
Researchers at NYU Langone Health discovered a link between a bladder gene and vesicoureteral reflux, a condition that causes urine to flow backward into the kidneys. The study suggests earlier detection and treatment of the condition could prevent kidney failure.
Researchers at NYU Langone Health and the University of Pennsylvania School of Medicine have discovered that hair follicles are the source of new cells for the skin's outermost layer, the epidermis. These stem cells reside in a protected area called the bulge, which migrates to the epidermis, replenishing the skin throughout life.
Scientists have discovered that the bone marrow is a source of mature liver cells, which could be used to develop new treatments for liver diseases. The findings suggest that healthy genes can be inserted into these stem cells to correct metabolic abnormalities.
A recent study published in the Proceedings of the National Academy of Sciences found that Jewish men share a common set of genetic signatures with non-Jews from the Middle East, including Palestinians, Syrians, and Lebanese. This suggests that Jews and Arabs are more closely related to one another than to non-Jews from other areas of ...
Researchers have identified a crucial molecule, DC-SIGN, that enables the AIDS virus to hijack dendritic cells, transporting it to immune system tissues where it infects T-lymphocytes. This breakthrough offers new avenues for developing treatments and potentially vaccines to prevent HIV infection.